About the VHIR
Here at the Vall d'Hebron Research Institute (VHIR) we promote biomedical research, innovation and teaching. Over 1,800 people are seeking to understand diseases today so the treatment can be improved tomorrow.
Research
We are working to understand diseases, to find out how they operate and to create better treatments for patients. Get to know about our groups and their lines of research.
People
People are the centre of the Vall d'Hebron Research Institute (VHIR). This is why we are bound by the principles of freedom of research, gender equality and professional attitudes that HRS4R promotes.
Clinical trials
Our work is not just basic or translational; we are leaders in clinical research. Enter and find about the clinical trials we are conducting and why we are a world reference in this field.
Progress
Our aim is to make the research carried out at the Vall d’Hebron Research Institute (VHIR) a driving force for transformation. How? By identifying new channels and solutions for the promotion of people's health and well-being.
Core facilities
We offer specialist support for researchers, internal and external alike, ranging from specific services to preparing complete projects. All this, from a perspective of quality and speed of response.
News
We offer you a gateway for staying up to date on everything going on at the Vall d’Hebron Research Institute (VHIR), from the latest news to future solidarity activities and initiatives that we are organising.
The Infection and Immunity in pediatric patients research group is a multidisciplinary pediatric research group made up of health professionals involved in translational research in the field of pediatric infectious diseases and immunodeficiencies, two related fields in terms of pathophysiology and clinical implications. It is a consolidated research group recognized by the AGAUR and is the only one with the accreditation of the Jeffrey Modell Foundation in research in the field of primary immunodeficiencies throughout the state.
The group was officially created in 2010, belongs to the area of Infectious Diseases and participates in the transversal programs of Advanced Translational Immunology and Rare Diseases and actively participates in national and international competitive projects, carries out multiple academic and industry-linked clinical trials and has increased the number and quality in recent years. In addition, it has its own laboratory specially dedicated to advanced immune studies.
IP: Roger Colobran Oriol Collaborators: Aina Aguiló Cucurull, Marina García Prat, Clara Franco Jarava, Andrea Martín Nalda, Laura Batlle Masó Funding agency: Instituto de Salud Carlos III Funding: 159720 Reference: PI20/00761 Duration: 01/01/2021 - 30/06/2025
IP: Antoni Soriano Arandes Collaborators: Jorgina Vila Soler, Joan Balcells Ramirez, Núria Worner Tomasa, Clara Franco Jarava, Cristina Andrés Vergés Funding agency: Fundació La Marató de TV3 Funding: 161075 Reference: 202134 Duration: 23/09/2021 - 22/09/2024
IP: Juan Jose Gonzalez Lopez Collaborators: Manuel Hernández González, Jose Angel Rodrigo Pendás, Aina Aguiló Cucurull, Alba Mir Cros, Albert Moreno Mingorance, Andrea Martín Nalda, Nuria Serre Delcor, Josep Roca Grande, Laura Batlle Masó Funding agency: Instituto de Salud Carlos III Funding: 123420 Reference: PI21/00132 Duration: 01/01/2022 - 31/12/2024
IP: Pere Soler Palacín Collaborators: Miriam Gonzalez Amores, Berta Sofia Fernandez Ledesma, Tamara Del Rio Higueras, Ariadna Martín Balcells, Amaia Latasa Arrazubi, Laura Roig Soria, Noemí Giménez Sanz Funding agency: EUROPEAN COMMISSION Funding: 475000 Reference: RBDCOV_HE-HLTH-CORONA2021 Duration: 01/12/2021 - 31/05/2024
PMID: 37595686 Journal: Transplantation and cellular therapy Year: 2023 Reference: Transplant Cell Ther. 2023 Aug 16:S2666-6367(23)01473-2. doi: 10.1016/j.jtct.2023.08.016. Impact factor: Publication type: Paper in international publication Authors: Belendez, Cristina; Benitez, Isabel; Bueno, David; de Heredia, Cristina Diaz; Echecopar, Carlos; Estival, Pablo; Fuentes, Carolina; Fuster, Jose Luis; Galan, Victor; Margarit, Adriana et al. DOI: 10.1016/j.jtct.2023.08.016
PMID: 37612182 Journal: Farmacia hospitalaria : organo oficial de expresion cientifica de la Sociedad Espanola de Farmacia H Year: 2023 Reference: Farm Hosp. 2023 Aug 21:S1130-6343(23)00102-2. doi: 10.1016/j.farma.2023.07.010. Impact factor: Publication type: Paper in national publication Authors: Campanario, Sonia Terradas; Herrero, David Campany; Larrosa-Garcia, Maria; Parra, Alba Pau; Polo, Aurora Fernandez; Ramirez, Carme Canete et al. DOI: 10.1016/j.farma.2023.07.010
PMID: 37723198 Journal: Communications Biology Year: 2023 Reference: Commun Biol. 2023 Sep 18;6(1):949. doi: 10.1038/s42003-023-05320-0. Impact factor: Publication type: Paper in international publication Authors: Berlanga, Pablo; Cairo, Stefano; Calvo, Julien; Casanova, Michela; Chastagner, Pascal; Cherkaoui, Sarah; Daudigeos-Dubus, Estelle; Delattre, Olivier; Dessen, Philippe; Droit, Robin et al. DOI: 10.1038/s42003-023-05320-0
PMID: 37164827 Journal: Anales de pediatria Year: 2023 Reference: An Pediatr (Engl Ed). 2023 May 8:S2341-2879(23)00097-2. doi: 10.1016/j.anpede.2023.04.006. Impact factor: Publication type: Paper in international publication Authors: Martin Begue, Nieves; Melendo Perez, Susana; Mirabet Mas, Julia; Morell Daniel, Mariona et al. DOI: 10.1016/j.anpede.2023.04.006
PMID: 35784294 Journal: Frontiers in Immunology Year: 2022 Reference: Front Immunol. 2022 Jun 17;13:897975. doi: 10.3389/fimmu.2022.897975. eCollection 2022. Impact factor: 7.561 Publication type: Letter or abstract Authors: Valenzuela, Irene; Franco-Jarava, Clara; Colobran, Roger; Batlle-Maso, Laura; Castells, Neus; Dieli-Crimi, Romina; Martinez-Gallo, Monica; Garcia-Prat, Marina; Riviere, Jacques G; Soler-Palacin, Pere et al. DOI: 10.3389/fimmu.2022.897975
PMID: 35708626 Journal: JOURNAL OF EXPERIMENTAL MEDICINE Year: 2022 Reference: J Exp Med. 2022 Aug 1;219(8). pii: 213287. doi: 10.1084/jem.20220131. Epub 2022 Jun 16. Impact factor: 14.307 Publication type: Paper in international publication Authors: El Baghdadi, Jamila, Bohlen, Jonathan, Liu, Zhiyong, Moncada-Velez, Marcela, Kendir-Demirkol, Yasemin, Jing, Huie, Bizien, Lucy, Marchal, Astrid, Abolhassani, Hassan, Delafontaine, Selket et al. DOI: 10.1084/jem.20220131
PMID: 35043109 Journal: Year: 2022 Reference: Res Sq. 2022 Jan 14. doi: 10.21203/rs.3.rs-1225906/v1. Impact factor: 0 Publication type: Letter or abstract Authors: Riviere, Jacques G, Garcia-Prat, Marina, Parra-Martinez, Alba, Soler-Palacin, Pere et al. DOI: 10.21203/rs.3.rs-1225906/v1
PMID: 35486339 Journal: JOURNAL OF CLINICAL IMMUNOLOGY Year: 2022 Reference: J Clin Immunol. 2022 Apr 29. pii: 10.1007/s10875-022-01257-x. doi: 10.1007/s10875-022-01257-x. Impact factor: 8.317 Publication type: Paper in international publication Authors: Martin-Nalda, Andrea, Alsina, Laia, Neth, Olaf, Olbrich, Peter, Martinez Pomar, Natalia, Lopez-Corbeto, Mireia, Garcia-Garcia, Ana, Kanderova, Veronika, Deya-Martinez, Angela, Riviere, Jaques G et al. DOI: 10.1007/s10875-022-01257-x
PMID: 34089457 Journal: JOURNAL OF CLINICAL IMMUNOLOGY Year: 2021 Reference: J Clin Immunol. 2021 Oct;41(7):1457-1462. doi: 10.1007/s10875-021-01078-4. Epub 2021 Jun 5. Impact factor: 8.317 Publication type: Paper in international publication Authors: Riviere, Jacques G, Malle, Louise, Bastard, Paul, Martin-Nalda, Andrea, Carpenter, Taya, Bush, Douglas, Patel, Roosheel, Colobran, Roger, Soler-Palacin, Pere, Casanova, Jean-Laurent et al. DOI: 10.1007/s10875-021-01078-4
PMID: 33775582 Journal: ANALES DE PEDIATRIA Year: 2021 Reference: An Pediatr (Engl Ed). 2021 Jan 27. pii: S1695-4033(21)00012-6. doi: 10.1016/j.anpedi.2021.01.006. Impact factor: 1.5 Publication type: Letter whit IF Authors: Bassets-Bosch, Alba, Raya-Munoz, Judith, Worner-Tomasa, Nuria, Melendo-Perez, Susana, Gonzalez-Peris, Sebastia et al. DOI: 10.1016/j.anpedi.2021.01.006
PMID: 32229130 Journal: ENFERMEDADES INFECCIOSAS Y MICROBIOLOGIA CLINICA Year: 2021 Reference: Enferm Infecc Microbiol Clin. 2021 Mar;39(3):134-138. doi: 10.1016/j.eimc.2020.02.015. Epub 2020 Mar 27. Impact factor: 1.731 Publication type: Paper in national publication Authors: Melendo, Susana, Fernandez-Polo, Aurora, Castellnou Asens, Ivette, Mendoza-Palomar, Natalia, Barnes-Mayolas, Meritxell, Soler-Palacin, Pere, Soler Palacin, Pere, Melendo Perez, Susana, Mendoza Palomar, Natalia, Nieves Larrosa Escartin, M et al. DOI: 10.1016/j.eimc.2020.02.015
PMID: 33462728 Journal: JOURNAL OF CLINICAL IMMUNOLOGY Year: 2021 Reference: J Clin Immunol. 2021 May;41(4):748-755. doi: 10.1007/s10875-020-00961-w. Epub 2021 Jan 18. Impact factor: 8.317 Publication type: Paper in international publication Authors: Alonso, Laura, Mendez-Echevarria, Ana, Rudilla, Francesc, Mozo, Yasmina, Soler-Palacin, Pere, Sisinni, Luisa, Bueno, David, Riviere, Jacques, de Paz, Raquel, Sanchez-Zapardiel, Elena et al. DOI: 10.1007/s10875-020-00961-w
PMID: 31887391 Journal: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY Year: 2020 Reference: J Allergy Clin Immunol. 2020 May;145(5):1452-1463. doi: 10.1016/j.jaci.2019.12.896. Epub 2019 Dec 27. Impact factor: 10.228 Publication type: Paper in international publication Authors: Tesch, Victoria Katharina, Abolhassani, Hassan, Shadur, Bella, Zobel, Joachim, Mareika, Yuliya, Sharapova, Svetlana, Karakoc-Aydiner, Elif, Riviere, Jacques G, Garcia-Prat, Marina, Moes, Nicolette et al. DOI: 10.1016/j.jaci.2019.12.896
PMID: 32335674 Journal: JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY Year: 2020 Reference: J Antimicrob Chemother. 2020 Aug 1;75(8):2264-2271. doi: 10.1093/jac/dkaa149. Impact factor: 5.439 Publication type: Paper in international publication Authors: Mendoza-Palomar, Natalia, Soques, Elena, Benitez-Carabante, Maria Isabel, Gonzalez-Amores, Miriam, Fernandez-Polo, Aurora, Renedo, Berta, Martin, Maria Teresa, Soler-Palacin, Pere, Diaz-de-Heredia, Cristina et al. DOI: 10.1093/jac/dkaa149
PMID: 32291562 Journal: JOURNAL OF CLINICAL IMMUNOLOGY Year: 2020 Reference: J Clin Immunol. 2020 May;40(4):602-609. doi: 10.1007/s10875-020-00775-w. Epub 2020 Apr 15. Impact factor: 6.78 Publication type: Paper in international publication Authors: Ridao-Manonellas, Saida, Fabregas-Bofill, Anna, Nunez-Rueda, Gloria, Gonzalez-Amores, Miriam, Garcia-Prat, Marina, Lopez-Seguer, Laura, Riviere, Jacques G, Martin-Nalda, Andrea, Mendoza-Palomar, Natalia, Melendo-Perez, Susana et al. DOI: 10.1007/s10875-020-00775-w
PMID: 31799703 Journal: CLINICAL AND EXPERIMENTAL IMMUNOLOGY Year: 2020 Reference: Clin Exp Immunol. 2020 Apr;200(1):61-72. doi: 10.1111/cei.13405. Epub 2020 Jan 19. Impact factor: 3.532 Publication type: Paper in international publication Authors: Alonso, Laura, Riviere, Jacques G, Soler-Palacin, Pere, Colobran, Roger, Sayos, Joan, Martinez-Gallo, Monica, Franco-Jarava, Clara, Ossowski, Stephan, Drechsel, Oliver, Magallon-Lorenz, Miriam et al. DOI: 10.1111/cei.13405
The results show that, in some patients with mutations in the X chromosome, the healthy gene is inactivated and the mutated gene manifests itself, which favors the onset of the disease.
The study, which is part of the European RECOMB project, is currently recruiting volunteers.
This clinical trial is part of the European project RBDCOV, led by HIPRA in which Vall d'Hebron participates, whose recruitment is still open.
