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Clinical Biochemistry, Drug Delivery & Therapy

The Clinical Biochemistry, Drug Delivery & Therapy (CB-DDT) group arises from the merger of two VHIR groups, the Clinical Biochemistry group and the Drug Delivery and Targeting group, which they develop preclinical and clinical research in the diagnosis and therapy of different diseases.

With a direct link to the Clinical Biochemistry service of the Vall d'Hebron Hospital, our scope of action ranges from the analysis of massive data coming from the service, the development of diagnostic and prognostic biomarkers, evaluation of existing therapies and the development of new therapeutic strategies based on nanotechnology.

In terms of specific pathologies or indications, the group has an extensive track record in basic and applied research in cancer (new biomarkers, therapeutic targets and new treatments), metabolopathies (biomarkers and improvements in enzyme replacement therapy), kidney disease and liver disease.

Team

Diego Baranda Martínez-Abasca

Diego Baranda Martínez-Abasca

Predoctoral researcher
Clinical Biochemistry, Drug Delivery & Therapy (CB-DDT)
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Belen Garcia Prats

Belen Garcia Prats

Research technician
Clinical Biochemistry, Drug Delivery & Therapy (CB-DDT)
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Clara Ramírez Serra

Clara Ramírez Serra

Predoctoral researcher
Clinical Biochemistry, Drug Delivery & Therapy (CB-DDT)
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Laura García Latorre

Laura García Latorre

Research technician
Clinical Biochemistry, Drug Delivery & Therapy (CB-DDT)
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Marina Giralt Arnaiz

Marina Giralt Arnaiz

Predoctoral researcher
Clinical Biochemistry, Drug Delivery & Therapy (CB-DDT)
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Sandra Mancilla Zamora

Sandra Mancilla Zamora

Research technician
Clinical Biochemistry, Drug Delivery & Therapy (CB-DDT)
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Diego Baranda Martínez-Abasca

Diego Baranda Martínez-Abasca

Predoctoral researcher
Clinical Biochemistry, Drug Delivery & Therapy (CB-DDT)
Read more
Belen Garcia Prats

Belen Garcia Prats

Research technician
Clinical Biochemistry, Drug Delivery & Therapy (CB-DDT)
Read more
Clara Ramírez Serra

Clara Ramírez Serra

Predoctoral researcher
Clinical Biochemistry, Drug Delivery & Therapy (CB-DDT)
Read more
Laura García Latorre

Laura García Latorre

Research technician
Clinical Biochemistry, Drug Delivery & Therapy (CB-DDT)
Read more
Marina Giralt Arnaiz

Marina Giralt Arnaiz

Predoctoral researcher
Clinical Biochemistry, Drug Delivery & Therapy (CB-DDT)
Read more
Sandra Mancilla Zamora

Sandra Mancilla Zamora

Research technician
Clinical Biochemistry, Drug Delivery & Therapy (CB-DDT)
Read more

Research lines

Disseny, síntesi i caracterització de nanosistemes terapèutics biodegradables

IP: Disseny, síntesi i caracterització de nanosistemes terapèutics biodegradables

Estudi de les bases moleculars i cel·lulars del càncer

IP: Joaquin Seras Franzoso

Estudi i Millora del procés de fecundació in vitro

IP: Maria del Pilar Reimundo Diaz-Fierros

Obtenció i us de vesícules extracel·lulars com vehicles per proteïnes i biomolècules

IP: Obtenció i us de vesícules extracel·lulars com vehicles per proteïnes i biomolècules

Projects

Hidrogeles Inteligentes y Biodegradables como Sistemas de Depósito para la Liberación Intraperitoneal Sostenida de Quimioterapéuticos para el Tratamiento Local del Cáncer de Ovario Avanzado (Smart-InOva)

IP: Diana Fernandes de Rafael
Collaborators: Fco Javier De la Torre Fdez de Vega, Simon Schwartz Navarro, Sandra Mancilla Zamora, Belen Garcia Prats
Funding agency: Instituto de Salud Carlos III
Funding: 177500
Reference: PI24/00745
Duration: 01/01/2025 - 31/12/2027

Resistencia a la insulina en la diabetes tipo 2: clarificando el mecanismo patogénico de la resistencia a la insulina miocárdica y los efectos de tratamientos con GLP-1 RA y SGLT2i

IP: José Raul Herance Camacho
Collaborators: Sofia Rodriguez Fernandez, Sergi Velasco Vila, Clara Ramírez Serra, Azahara Maria Palomar Muñoz, Cristina Gamez Cenzano, Jana Vidal Otero, Carolina Aparicio Gomez, Alberto Roque Pérez, Mercè Abad Martín, Olga Simó Servat, Pedro Alejandro Gil Millán, Maria Nazarena Pizzi, Emily Betancourt Fernández, Enrique Franky Vargas, Martha Sahylí Ortega Pijeira, Emily Betancourt Fernández
Funding agency: Instituto de Salud Carlos III
Funding: 252500
Reference: PI24/01356
Duration: 01/01/2025 - 31/12/2027

EXPAND-EV: EXPANDing the value of Extracellular Vesicles as carriers of biomarker and therapy in precision healhcare

IP: Joaquin Seras Franzoso
Collaborators: -
Funding agency: EUROPEAN COMMISSION
Funding: 82800
Reference: EXPAND-EV/EC/MSCA-SE/2024/SERAS
Duration: 01/01/2025 - 31/12/2028

SPM4.0: Autonomous Scanning Probe Microscopy for Life Sciences and Medicine powered by Artificial Intelligence

IP: -
Collaborators: -
Funding agency: EUROPEAN COMMISSION
Funding: 251971.2
Reference: SPM40_F.ANDRADE_MSCA-DN2023
Duration: 01/11/2024 - 31/10/2028

Blog

News

The study results show that the local presence of IL-1β promotes the development of myeloid cells with an immunosuppressive function.

The grants promote new therapeutic strategies and diagnostic tools in highly complex tumors such as glioblastoma, triple-negative breast cancer, and endometrial cancer.

The project aims to improve prevention, diagnosis, and treatment through computational biomedicine, innovative therapies, and the transfer of knowledge into clinical practice.