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Clinical Biochemistry, Drug Delivery & Therapy

The Clinical Biochemistry, Drug Delivery & Therapy (CB-DDT) group arises from the merger of two VHIR groups, the Clinical Biochemistry group and the Drug Delivery and Targeting group, which they develop preclinical and clinical research in the diagnosis and therapy of different diseases.

With a direct link to the Clinical Biochemistry service of the Vall d'Hebron Hospital, our scope of action ranges from the analysis of massive data coming from the service, the development of diagnostic and prognostic biomarkers, evaluation of existing therapies and the development of new therapeutic strategies based on nanotechnology.

In terms of specific pathologies or indications, the group has an extensive track record in basic and applied research in cancer (new biomarkers, therapeutic targets and new treatments), metabolopathies (biomarkers and improvements in enzyme replacement therapy), kidney disease and liver disease.

Team

Fernando Moreno Flores

Fernando Moreno Flores

Clinical Biochemistry, Drug Delivery & Therapy (CB-DDT)
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Ana Maria Casas Guerrero

Ana Maria Casas Guerrero

Research technician
Clinical Biochemistry, Drug Delivery & Therapy (CB-DDT)
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Andjelo Beletic

Andjelo Beletic

Predoctoral researcher
Clinical Biochemistry, Drug Delivery & Therapy (CB-DDT)
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Andrea Dorado Martín

Andrea Dorado Martín

Research technician
Clinical Biochemistry, Drug Delivery & Therapy (CB-DDT)
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Concepció Jacobs Cachá

Concepció Jacobs Cachá

Main researcher
Clinical Biochemistry, Drug Delivery & Therapy (CB-DDT)
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Eirini Kyriakopoulou

Eirini Kyriakopoulou

Predoctoral researcher
Clinical Biochemistry, Drug Delivery & Therapy (CB-DDT)
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Fernando Moreno Flores

Fernando Moreno Flores

Clinical Biochemistry, Drug Delivery & Therapy (CB-DDT)
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Ana Maria Casas Guerrero

Ana Maria Casas Guerrero

Research technician
Clinical Biochemistry, Drug Delivery & Therapy (CB-DDT)
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Andjelo Beletic

Andjelo Beletic

Predoctoral researcher
Clinical Biochemistry, Drug Delivery & Therapy (CB-DDT)
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Andrea Dorado Martín

Andrea Dorado Martín

Research technician
Clinical Biochemistry, Drug Delivery & Therapy (CB-DDT)
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Concepció Jacobs Cachá

Concepció Jacobs Cachá

Main researcher
Clinical Biochemistry, Drug Delivery & Therapy (CB-DDT)
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Eirini Kyriakopoulou

Eirini Kyriakopoulou

Predoctoral researcher
Clinical Biochemistry, Drug Delivery & Therapy (CB-DDT)
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Projects

Project-COMFORT: Patient-Centric blOod saMpling FOr impRoved healThcare

IP: Simon Schwartz Navarro
Collaborators: Roser Ferrer Costa, Concepció Jacobs Cachá
Funding agency: EUROPEAN COMMISSION
Funding: 288262.5
Reference: COMFORT- HE--JU-IHI-2023-04
Duration: 01/11/2024 - 30/04/2028

ERDERA: European Rare Disease Research Alliance

IP: M Mar Mañu Pereira
Collaborators: Augusto Cesar Sao Aviles, Patricia González Ruiz, Claire Diot, Miguel Chillon Rodriguez, Simon Schwartz Navarro, Sara Isabel Reidel
Funding agency: EUROPEAN COMMISSION
Funding: 1252083.33
Reference: ERDERA/EC/HLTH-2023-DISEASE-07-01/2023/MAÑU
Duration: 01/09/2024 - 31/08/2031

Evaluation of an innovative strategy based on nanoparticles-loaded hydrogels as a safe and sustained intraperitoneal chemotherapy in mucinous adenocarcinomas

IP: -
Collaborators: Roser Ferrer Costa, Diana Fernandes de Rafael
Funding agency: Asociación Española Contra el Cáncer
Funding: 10000
Reference: SNRGS247164DASI
Duration: 01/06/2024 - 31/05/2026

ARTEMIs: AcceleRating the Translation of virtual twins towards a pErsonalised Management of fatty lIver patients

IP: José Raul Herance Camacho
Collaborators: Beatriz Minguez Rosique, Clara Ramírez Serra, Cristina Gamez Cenzano, Juan Manuel Pericàs Pulido, Nuria Roson Gradaille, Andreea Ciudin Mihai, Alberto Roque Pérez, ARTEMIs: AcceleRating the Translation of virtual twins towards a pErsonalised Management of fatty lIver patients, Maria Nazarena Pizzi, Ramón Vilallonga Puy, Enrique Franky Vargas, Carolina Aparicio Gomez
Funding agency: EUROPEAN COMMISSION
Funding: 724000
Reference: ARTEMIS_HE-HLTH2023
Duration: 01/01/2024 - 31/12/2027

Blog

News

The study results show that the local presence of IL-1β promotes the development of myeloid cells with an immunosuppressive function.

The grants promote new therapeutic strategies and diagnostic tools in highly complex tumors such as glioblastoma, triple-negative breast cancer, and endometrial cancer.

The project aims to improve prevention, diagnosis, and treatment through computational biomedicine, innovative therapies, and the transfer of knowledge into clinical practice.