Skip to main content

Clinical Biochemistry, Drug Delivery & Therapy

The Clinical Biochemistry, Drug Delivery & Therapy (CB-DDT) group arises from the merger of two VHIR groups, the Clinical Biochemistry group and the Drug Delivery and Targeting group, which they develop preclinical and clinical research in the diagnosis and therapy of different diseases.

With a direct link to the Biochemistry service of the Vall d'Hebron Hospital, our scope of action ranges from the analysis of massive data coming from the service, the development of diagnostic and prognostic biomarkers, evaluation of existing therapies and the development of new therapeutic strategies based on nanotechnology.

In terms of specific pathologies or indications, the group has an extensive track record in basic and applied research in cancer (new biomarkers, therapeutic targets and new treatments), metabolopathies (biomarkers and improvements in enzyme replacement therapy), kidney disease and liver disease.

Team

Laura García Latorre

Laura García Latorre

Research technician
Clinical Biochemistry, Drug Delivery & Therapy (CB-DDT)
Read more
Marina Giralt Arnaiz

Marina Giralt Arnaiz

Predoctoral researcher
Clinical Biochemistry, Drug Delivery & Therapy (CB-DDT)
Read more
Sandra Mancilla Zamora

Sandra Mancilla Zamora

Research technician
Clinical Biochemistry, Drug Delivery & Therapy (CB-DDT)
Read more
Fernando Moreno Flores

Fernando Moreno Flores

Predoctoral researcher
Clinical Biochemistry, Drug Delivery & Therapy (CB-DDT)
Read more
Ana Cindric

Ana Cindric

Senior researcher
Clinical Biochemistry, Drug Delivery & Therapy (CB-DDT)
Read more
Ana Maria Casas Guerrero

Ana Maria Casas Guerrero

Research technician
Clinical Biochemistry, Drug Delivery & Therapy (CB-DDT)
Read more
Laura García Latorre

Laura García Latorre

Research technician
Clinical Biochemistry, Drug Delivery & Therapy (CB-DDT)
Read more
Marina Giralt Arnaiz

Marina Giralt Arnaiz

Predoctoral researcher
Clinical Biochemistry, Drug Delivery & Therapy (CB-DDT)
Read more
Sandra Mancilla Zamora

Sandra Mancilla Zamora

Research technician
Clinical Biochemistry, Drug Delivery & Therapy (CB-DDT)
Read more
Fernando Moreno Flores

Fernando Moreno Flores

Predoctoral researcher
Clinical Biochemistry, Drug Delivery & Therapy (CB-DDT)
Read more
Ana Cindric

Ana Cindric

Senior researcher
Clinical Biochemistry, Drug Delivery & Therapy (CB-DDT)
Read more
Ana Maria Casas Guerrero

Ana Maria Casas Guerrero

Research technician
Clinical Biochemistry, Drug Delivery & Therapy (CB-DDT)
Read more

Projects

Hidrogeles Inteligentes y Biodegradables como Sistemas de Depósito para la Liberación Intraperitoneal Sostenida de Quimioterapéuticos para el Tratamiento Local del Cáncer de Ovario Avanzado (Smart-InOva)

IP: Diana Fernandes de Rafael
Collaborators: Julia German Cortes, Fco Javier De la Torre Fdez de Vega, Simon Schwartz Navarro, Sandra Mancilla Zamora, Belen Garcia Prats
Funding agency: Instituto de Salud Carlos III
Funding: 177500
Reference: PI24/00745
Duration: 01/01/2025 - 31/12/2027

Resistencia a la insulina en la diabetes tipo 2: clarificando el mecanismo patogénico de la resistencia a la insulina miocárdica y los efectos de tratamientos con GLP-1 RA y SGLT2i

IP: José Raul Herance Camacho
Collaborators: Sofia Rodriguez Fernandez, Sergi Velasco Vila, Clara Ramírez Serra, Azahara Maria Palomar Muñoz, Cristina Gamez Cenzano, Jana Vidal Otero, Carolina Aparicio Gomez, Alberto Roque Pérez, Mercè Abad Martín, Olga Simó Servat, Pedro Alejandro Gil Millán, Emily Betancourt Fernández, Martha Sahylí Ortega Pijeira, Maria Nazarena Pizzi, Enrique Franky Vargas
Funding agency: Instituto de Salud Carlos III
Funding: 252500
Reference: PI24/01356
Duration: 01/01/2025 - 31/12/2027

EXPAND-EV: EXPANDing the value of Extracellular Vesicles as carriers of biomarker and therapy in precision healhcare

IP: Joaquin Seras Franzoso
Collaborators: -
Funding agency: EUROPEAN COMMISSION
Funding: 82800
Reference: EXPAND-EV/EC/MSCA-SE/2024/SERAS
Duration: 01/01/2025 - 31/12/2028

SPM4.0: Autonomous Scanning Probe Microscopy for Life Sciences and Medicine powered by Artificial Intelligence

IP: Diana Fernandes de Rafael
Collaborators: Vincenzo Montanarella
Funding agency: EUROPEAN COMMISSION
Funding: 251971.2
Reference: SPM40_F.ANDRADE_MSCA-DN2023
Duration: 01/11/2024 - 31/10/2028

Blog

News

The project’s 4th annual meeting was recently held as part of the Fortalece–Salud programme of the Carlos III Health Institute.

The families of the professionals had the opportunity to visit the facilities and discover how we work at the institution.

The new system, made of cellulose and chitosan, enables sustained release of docetaxel and has demonstrated antitumor activity in preclinical models of ovarian cancer and glioblastoma.