About the VHIR
Here at the Vall d'Hebron Research Institute (VHIR) we promote biomedical research, innovation and teaching. Over 1,800 people are seeking to understand diseases today so the treatment can be improved tomorrow.
Research
We are working to understand diseases, to find out how they operate and to create better treatments for patients. Get to know about our groups and their lines of research.
People
People are the centre of the Vall d'Hebron Research Institute (VHIR). This is why we are bound by the principles of freedom of research, gender equality and professional attitudes that HRS4R promotes.
Clinical trials
Our work is not just basic or translational; we are leaders in clinical research. Enter and find about the clinical trials we are conducting and why we are a world reference in this field.
Progress
Our aim is to make the research carried out at the Vall d’Hebron Research Institute (VHIR) a driving force for transformation. How? By identifying new channels and solutions for the promotion of people's health and well-being.
Core facilities
We offer specialist support for researchers, internal and external alike, ranging from specific services to preparing complete projects. All this, from a perspective of quality and speed of response.
News
We offer you a gateway for staying up to date on everything going on at the Vall d’Hebron Research Institute (VHIR), from the latest news to future solidarity activities and initiatives that we are organising.
The Systemic Diseases group performs translational research based on at least 300 patients with systemic lupus erytomatosus (SLE), antiphospholipid syndrome (APS), systemic sclerosis, vasculitis, dermatomyitis, Sjörgen syndrome or autoinflammatory syndromes in order to better understand their pathogenesis (both at the immunological and genetic regulation level), study their clinical and biological expression (through the detection of new markers that help characterize each of the autoimmune diseases), study morbimortality (through epidemiological studies) and analyse patients' response to medications. With these goals in mind, we seek to improve the diagnosis, clinical monitoring, and prognosis of our patients.
PMID: 33811358 Journal: ALLERGY Year: 2021 Reference: Allergy. 2021 Oct;76(10):2952-2964. doi: 10.1111/all.14838. Impact factor: 13.146 Publication type: Paper in international publication Authors: Bosnic-Anticevich, Sinthia, Agache, Ioana, Blain, Hubert, Jutel, Marek, Ventura, Maria Teresa, Worm, Margitta, Del Giacco, Stefano, Benetos, Athanasios, Bilo, M Beatrice, Czarlewski, Wienczyslawa et al. DOI: 10.1111/all.14838
PMID: 32423687 Journal: MEDICINA CLINICA Year: 2021 Reference: Med Clin (Barc). 2021 Apr 9;156(7):362-363. doi: 10.1016/j.medcli.2020.01.040. Epub 2020 May 16. Impact factor: 1.725 Publication type: Letter or abstract Authors: Vega-Cano, Sharela, Cordero-Vazquez, Efrain, Mestre-Torres, Jaume et al. DOI: 10.1016/j.medcli.2020.01.040
PMID: 33655502 Journal: ALLERGY Year: 2021 Reference: Allergy. 2021 Aug;76(8):2433-2446. doi: 10.1111/all.14797. Epub 2021 Mar 27. Impact factor: 13.146 Publication type: Review in international publication Authors: Skypala, Isabel J, Bartra, Joan, Ebo, Didier G, Antje Faber, Margaretha, Fernandez-Rivas, Montserrat, Gomez, Francisca, Luengo, Olga, Till, Stephen J, Asero, Riccardo, Barber, Domingo et al. DOI: 10.1111/all.14797
PMID: 33766615 Journal: AUTOIMMUNITY REVIEWS Year: 2021 Reference: Autoimmun Rev. 2021 May;20(5):102793. doi: 10.1016/j.autrev.2021.102793. Epub 2021 Mar 22. Impact factor: 9.754 Publication type: Letter or abstract Authors: Rubio-Rivas, Manuel, Corbella, Xavier, Guillen-Del-Castillo, Alfredo, Vilella, Carles Tolosa, Arguelles, Dolores Colunga, Aznar, Carmen Pilar Simeon, Pla, Vicent Fonollosa, Trigo, Sabela Sanchez, de la Puebla Gimenez, Rafael Angel Fernandez, Argibay, Ana et al. DOI: 10.1016/j.autrev.2021.102793
PMID: 30955224 Journal: ALLERGY Year: 2019 Reference: Allergy. 2019 Nov;74(11):2087-2102. doi: 10.1111/all.13805. Epub 2019 Jul 15. Impact factor: 6.771 Publication type: Paper in international publication Authors: Wallace, D, Caraballo, L, Cardona, V, Casale, T, Cecchi, L, Chu, D K, Costa, E, Cruz, A A, Czarlewski, W, Durham, S R et al. DOI: 10.1111/all.13805
PMID: 30907380 Journal: Revista Espanola de Salud Publica Year: 2019 Reference: Rev Esp Salud Publica. 2019 Mar 25;93. Impact factor: 0.635 Publication type: Letter or abstract Authors: Arraiza, Antonio, Casado, Paloma, Codesido, Maria, Pascual, Cesar, Saldana, Roberto, Gil, Angel, Palau, Javier, Hinojosa, Joaquin, Marsal, Sara, Puig, Lluis et al. DOI:
PMID: 30893475 Journal: EUROPEAN JOURNAL OF IMMUNOLOGY Year: 2019 Reference: Eur J Immunol. 2019 Jul;49(7):1107-1116. doi: 10.1002/eji.201848065. Epub 2019 Apr 2. Impact factor: 4.695 Publication type: Paper in international publication Authors: Medina-Varo, Fermin, Rodriguez, Carmen, Anez, Gustavo A, Campos-Caro, Antonio, Rodriguez-Bayona, Beatriz, de la Varga-Martinez, Raquel et al. DOI: 10.1002/eji.201848065
PMID: 30872671 Journal: Scientific Reports Year: 2019 Reference: Sci Rep. 2019 Mar 14;9(1):4579. doi: 10.1038/s41598-019-40874-2. Impact factor: 4.011 Publication type: Paper in international publication Authors: Arostegui, Juan I, Rabionet, Raquel, Remesal, Agustin, Mensa-Vilaro, Anna, Murias, Sara, Alcobendas, Rosa, Gonzalez-Roca, Eva, Ruiz-Ortiz, Estibaliz, Anton, Jordi, Iglesias, Estibaliz et al. DOI: 10.1038/s41598-019-40874-2
PMID: 28079503 Journal: CLINICAL AND EXPERIMENTAL RHEUMATOLOGY Year: 2017 Reference: Clin Exp Rheumatol. 2017 Nov-Dec;35 Suppl 108(6):27-31. Epub 2017 Jan 9. Impact factor: 2.634 Publication type: Paper in international publication Authors: Bujan-Rivas, Segundo, Basagana, Maria, Sena, Francisca, Mendez, Maria, Dordal, Maria Teresa, Gonzalez-Roca, Eva, Ruiz-Ortiz, Estibaliz, Mensa-Vilaro, Anna, Plaza, Susana, Modesto, Consuelo et al. DOI:
PMID: 28041642 Journal: AMERICAN JOURNAL OF HUMAN GENETICS Year: 2017 Reference: Am J Hum Genet. 2017 Jan 5;100(1):64-74. doi: 10.1016/j.ajhg.2016.11.013. Epub 2016 Dec 29. Impact factor: 9.025 Publication type: Paper in international publication Authors: Schonau, Verena, Monach, Paul A, Castaneda, Santos, Solans, Roser, Morado, Inmaculada C, Narvaez, Javier, Ramentol-Sintas, Marc, Pease, Colin T, Dasgupta, Bhaskar, Watts, Richard et al. DOI: 10.1016/j.ajhg.2016.11.013
PMID: 28052319 Journal: BRITISH JOURNAL OF PHARMACOLOGY Year: 2017 Reference: Br J Pharmacol. 2017 Mar;174(5):345-369. doi: 10.1111/bph.13702. Epub 2017 Feb 1. Impact factor: 5.491 Publication type: Review in national publication Authors: Castro-Marrero, Jesus, Saez-Francas, Naia, Santillo, Dafna, Alegre, Jose et al. DOI: 10.1111/bph.13702
PMID: 27999855 Journal: Journal of Nutrition Health & Aging Year: 2017 Reference: J Nutr Health Aging. 2017;21(1):92-104. doi: 10.1007/s12603-016-0803-1. Impact factor: 2.772 Publication type: Paper in international publication Authors: Siciliano, P, Goswami, N, Guldemond, N A, Henderson, D, Hinkema, M J, Liotta, G, Mair, A, Molloy, W, Monaco, A, Monsonis-Paya, I et al. DOI: 10.1007/s12603-016-0803-1
PMID: 24461380 Journal: J AUTOIMMUN Year: 2014 Reference: J Autoimmun. 2014 Feb-Mar;48-49:118-21. doi: 10.1016/j.jaut.2014.01.025. Epub 2014 Jan 22. Impact factor: 7.018 Publication type: Review in international publication Authors: Milisenda, J C, Selva-O'Callaghan, A, Grau, J M et al. DOI: 10.1016/j.jaut.2014.01.025
PMID: 24452223 Journal: INT J CARDIOL Year: 2014 Reference: Int J Cardiol. 2014 Mar 1;172(1):127-31. doi: 10.1016/j.ijcard.2013.12.169. Epub 2014 Jan 8. Impact factor: 6.175 Publication type: Paper in international publication Authors: Formiga, Francesc, Chivite, David, Conde, Alicia, Ruiz-Laiglesia, Fernando, Franco, Alvaro Gonzalez, Bocanegra, Carmen Perez, Manzano, Luis, Perez-Barquero, Manuel Montero et al. DOI: 10.1016/j.ijcard.2013.12.169
PMID: 24438879 Journal: ARCH GERONTOL GERIAT Year: 2014 Reference: Arch Gerontol Geriatr. 2014 May-Jun;58(3):460-4. doi: 10.1016/j.archger.2013.12.006. Epub 2014 Jan 2. Impact factor: 1.525 Publication type: Paper in international publication Authors: San-Jose, Antonio, Agusti, Antonia, Vidal, Xavier, Barbe, Jose, Torres, Olga H, Ramirez-Duque, Nieves, Garcia, Juana, Fernandez-Moyano, Antonio, Lopez-Soto, Alfonso, Formiga, Francesc et al. DOI: 10.1016/j.archger.2013.12.006
PMID: 24356492 Journal: DERMATOLOGY Year: 2014 Reference: Dermatology. 2014;228(1):27-30. doi: 10.1159/000356779. Epub 2013 Dec 14. Impact factor: 1.685 Publication type: Paper in international publication Authors: Pinal-Fernandez, Iago, Solans-Laque, Roser et al. DOI: 10.1159/000356779
The new technology allows more sensitive detection of scleroderma patients' autoantibodies, which are related to the severity and progression of the disease.
Researchers have used an innovative protocol to identify people with this autoimmune disease who have a higher risk of cancer.
It will allow the promotion of research on systemic autoimmune-based diseases that especially affect women of childbearing age and, therefore, can also appear during pregnancy.
