About the VHIR
Here at the Vall d'Hebron Research Institute (VHIR) we promote biomedical research, innovation and teaching. Over 1,800 people are seeking to understand diseases today so the treatment can be improved tomorrow.
Research
We are working to understand diseases, to find out how they operate and to create better treatments for patients. Get to know about our groups and their lines of research.
People
People are the centre of the Vall d'Hebron Research Institute (VHIR). This is why we are bound by the principles of freedom of research, gender equality and professional attitudes that HRS4R promotes.
Clinical trials
Our work is not just basic or translational; we are leaders in clinical research. Enter and find about the clinical trials we are conducting and why we are a world reference in this field.
Progress
Our aim is to make the research carried out at the Vall d’Hebron Research Institute (VHIR) a driving force for transformation. How? By identifying new channels and solutions for the promotion of people's health and well-being.
Core facilities
We offer specialist support for researchers, internal and external alike, ranging from specific services to preparing complete projects. All this, from a perspective of quality and speed of response.
News
We offer you a gateway for staying up to date on everything going on at the Vall d’Hebron Research Institute (VHIR), from the latest news to future solidarity activities and initiatives that we are organising.
The Systemic Diseases group performs translational research based on at least 300 patients with systemic lupus erytomatosus (SLE), antiphospholipid syndrome (APS), systemic sclerosis, vasculitis, dermatomyitis, Sjörgen syndrome or autoinflammatory syndromes in order to better understand their pathogenesis (both at the immunological and genetic regulation level), study their clinical and biological expression (through the detection of new markers that help characterize each of the autoimmune diseases), study morbimortality (through epidemiological studies) and analyse patients' response to medications. With these goals in mind, we seek to improve the diagnosis, clinical monitoring, and prognosis of our patients.
PMID: 33742673 Journal: RHEUMATOLOGY Year: 2021 Reference: Rheumatology (Oxford). 2021 Dec 24;61(1):154-162. doi: 10.1093/rheumatology/keab279. Impact factor: 7.58 Publication type: Paper in international publication Authors: Bellocchi, Chiara, Callejas-Moraga, Authors' Names Eduardo Luis, Del-Castillo, Alfredo Guillen-, Perurena-Prieto, Janire, Sanz-Martinez, Maria Teresa, Fonollosa-Pla, Vicente, Lorite-Gomez, Karen, Severino, Adriana, Simeon-Aznar, Carmen P, Mahler, Michael et al. DOI: 10.1093/rheumatology/keab279
PMID: 33738082 Journal: Journal of Extracellular Vesicles Year: 2021 Reference: J Extracell Vesicles. 2021 Mar;10(5):e12058. doi: 10.1002/jev2.12058. Epub 2021 Mar 12. Impact factor: 25.841 Publication type: Paper in international publication Authors: Seras-Franzoso, Joaquin, Diaz-Riascos, Zamira V, Corchero, Jose Luis, Gonzalez, Patricia, Garcia-Aranda, Natalia, Mandana, Monica, Riera, Roger, Boullosa, Ana, Mancilla, Sandra, Grayston, Alba et al. DOI: 10.1002/jev2.12058
PMID: 33730365 Journal: ALLERGY Year: 2021 Reference: Allergy. 2021 Aug;76(8):2354-2366. doi: 10.1111/all.14815. Epub 2021 May 14. Impact factor: 13.146 Publication type: Paper in international publication Authors: Cingi, Cemal, Hagemann, Jan, Onorato, Gabrielle L, Jutel, Marek, Akdis, Cezmi A, Agache, Ioana, Zuberbier, Torsten, Czarlewski, Wienczyslawa, Mullol, Joaquim, Bedbrook, Anna et al. DOI: 10.1111/all.14815
PMID: 32593414 Journal: MEDICINA CLINICA Year: 2021 Reference: Med Clin (Barc). 2021 Mar 26;156(6):263-269. doi: 10.1016/j.medcli.2020.04.030. Epub 2020 Jun 24. Impact factor: 1.725 Publication type: Paper in national publication Authors: San-Jose, Antonio, Perez-Bocanegra, Carmen, Agusti, Antonia, Laorden, Helena, Gost, Jordi, Vidal, Xavier, Oropeza, Vanessa, Romero, Rosa et al. DOI: 10.1016/j.medcli.2020.04.030
PMID: 30861336 Journal: Arthritis & Rheumatology Year: 2019 Reference: Arthritis Rheumatol. 2019 Aug;71(8):1371-1376. doi: 10.1002/art.40883. Epub 2019 Jun 18. Impact factor: 9.002 Publication type: Paper in international publication Authors: Pinal-Fernandez, Iago, Amici, David R, Parks, Cassie A, Derfoul, Assia, Casal-Dominguez, Maria, Pak, Katherine, Yeker, Richard, Plotz, Paul, Milisenda, Jose C, Selva-O'Callaghan, Albert et al. DOI: 10.1002/art.40883
PMID: 30847342 Journal: Frontiers in Medicine Year: 2019 Reference: Front Med (Lausanne). 2019 Feb 21;6:28. doi: 10.3389/fmed.2019.00028. eCollection 2019. Impact factor: 3.113 Publication type: Paper in international publication Authors: Veronez, Camila Lopes, Aabom, Anne, Martin, Renan Paulo, Filippelli-Silva, Rafael, Goncalves, Rozana Fatima, Nicolicht, Priscila, Mendes, Agatha Ribeiro, Da Silva, Jane, Guilarte, Mar, Grumach, Anete Sevciovic et al. DOI: 10.3389/fmed.2019.00028
PMID: 30808881 Journal: Scientific Reports Year: 2019 Reference: Sci Rep. 2019 Feb 26;9(1):2777. doi: 10.1038/s41598-019-39113-5. Impact factor: 4.011 Publication type: Paper in international publication Authors: Espinosa, Gerard, Burillo-Sanz, Sergio, Montes-Cano, Marco-Antonio, Garcia-Lozano, Jose-Raul, Olivas-Martinez, Israel, Ortego-Centeno, Norberto, Garcia-Hernandez, Francisco-Jose, Julia, Maria Rosa, Solans, Roser, Blanco, Ricardo et al. DOI: 10.1038/s41598-019-39113-5
PMID: 30789234 Journal: RHEUMATOLOGY Year: 2019 Reference: Rheumatology (Oxford). 2019 Jul 1;58(7):1299-1301. doi: 10.1093/rheumatology/kez015. Impact factor: 5.149 Publication type: Paper in international publication Authors: Simeon, Carmen Pilar, Carreria, Patricia, Ortego-Centeno, Norberto, Vicente, Esther, Worthington, Jane, Herrick, Ariane L, Martin, Javier, Teruel, Maria, Lopez-Isac, Elena, Duffus, Kate et al. DOI: 10.1093/rheumatology/kez015
PMID: 24351900 Journal: J NEUROL SCI Year: 2014 Reference: J Neurol Sci. 2014 Feb 15;337(1-2):167-72. doi: 10.1016/j.jns.2013.12.003. Epub 2013 Dec 7. Impact factor: 2.262 Publication type: Paper in international publication Authors: Saez-Francas, Naia, Hernandez-Vara, Jorge, Corominas-Roso, Margarita, Alegre, Jose, Jacas, Carlos, Casas, Miguel et al. DOI: 10.1016/j.jns.2013.12.003
PMID: 24162151 Journal: RHEUMATOLOGY Year: 2014 Reference: Rheumatology (Oxford). 2014 Feb;53(2):321-31. doi: 10.1093/rheumatology/ket349. Epub 2013 Oct 25. Impact factor: 4.435 Publication type: Paper in international publication Authors: Ripoll, Mar, Pinilla, Blanca, Akasbi, Miriam, Fonseca, Eva, Canora, Jesus, Nadal, Maria-Elvira, Red, Gloria de la, Fernandez-Regal, Ines, Jimenez-Heredia, Iratxe, Bosch, Josep-Angel et al. DOI: 10.1093/rheumatology/ket349
PMID: 24022944 Journal: ARTHRIT CARE RES Year: 2014 Reference: Arthritis Care Res (Hoboken). 2014 Feb;66(2):334. doi: 10.1002/acr.22157. Impact factor: 4.039 Publication type: Letter whit IF Authors: Ortego-Centeno, Norberto, Simeon-Aznar, Carmen-Pilar, Callejas-Rubio, Jose-Luis, Rios-Fernandez, Raquel et al. DOI: 10.1002/acr.22157
PMID: 24354303 Journal: ANAL CHEM Year: 2014 Reference: Anal Chem. 2014 Jan 21;86(2):1160-9. doi: 10.1021/ac403110u. Epub 2013 Dec 31. Impact factor: 5.825 Publication type: Paper in international publication Authors: Alonso, Arnald, Rodriguez, Miguel A, Vinaixa, Maria, Tortosa, Raul, Correig, Xavier, Julia, Antonio, Marsal, Sara et al. DOI: 10.1021/ac403110u
The new technology allows more sensitive detection of scleroderma patients' autoantibodies, which are related to the severity and progression of the disease.
Researchers have used an innovative protocol to identify people with this autoimmune disease who have a higher risk of cancer.
It will allow the promotion of research on systemic autoimmune-based diseases that especially affect women of childbearing age and, therefore, can also appear during pregnancy.
