About the VHIR
Here at the Vall d'Hebron Research Institute (VHIR) we promote biomedical research, innovation and teaching. Over 1,800 people are seeking to understand diseases today so the treatment can be improved tomorrow.
Research
We are working to understand diseases, to find out how they operate and to create better treatments for patients. Get to know about our groups and their lines of research.
People
People are the centre of the Vall d'Hebron Research Institute (VHIR). This is why we are bound by the principles of freedom of research, gender equality and professional attitudes that HRS4R promotes.
Clinical trials
Our work is not just basic or translational; we are leaders in clinical research. Enter and find about the clinical trials we are conducting and why we are a world reference in this field.
Progress
Our aim is to make the research carried out at the Vall d’Hebron Research Institute (VHIR) a driving force for transformation. How? By identifying new channels and solutions for the promotion of people's health and well-being.
Core facilities
We offer specialist support for researchers, internal and external alike, ranging from specific services to preparing complete projects. All this, from a perspective of quality and speed of response.
News
We offer you a gateway for staying up to date on everything going on at the Vall d’Hebron Research Institute (VHIR), from the latest news to future solidarity activities and initiatives that we are organising.
The Biomedical Research in Urology group is interested in the study of hormone-dependent cancers, in particular prostate cancer (but not limited to it).
Our efforts are focused on finding, on the one hand, tools that help us in the early diagnosis of the disease, in the best differentiation of tumors according to their aggressiveness and their response to therapy, and finally in finding effective therapies against it.
From a molecular point of view, we focus our studies mainly on cell signaling processes related to the cell cycle and mitosis (with kinesins, kinases and ubiquitin ligases as main targets).
Our multidisciplinary group is made up of molecular biologists and urologists, and we collaborate with oncologists, pathologists and specialists in other diseases when required.
We work with in silico data obtained with different "omics" techniques, samples and clinical data from patients, in vitro and in vivo models, to answer the questions raised.
PMID: 37760511 Journal: Cancers Year: 2023 Reference: Cancers (Basel). 2023 Sep 13;15(18):4543. doi: 10.3390/cancers15184543. Impact factor: Publication type: Paper in international publication Authors: Abascal, Jose M; Abascal, Jose M; Aisian, Ignacio; Celma, Anna; Celma, Anna; Manuel, Gemma Garcia-de; Morote, Juan; Morote, Juan; Munoz-Rivero, Marta V; Munoz-Rodriguez, Jesus et al. DOI: 10.3390/cancers15184543
PMID: 35471698 Journal: Molecular Diagnosis & Therapy Year: 2022 Reference: Mol Diagn Ther. 2022 May;26(3):273-281. doi: 10.1007/s40291-022-00584-4. Epub 2022 Apr 26. Impact factor: Publication type: Review in international publication Authors: Campistol, Miriam; Celma, Ana; Morote, Juan; Planas, Jacques; Regis, Lucas; Trilla, Enrique et al. DOI: 10.1007/s40291-022-00584-4
PMID: 35417652 Journal: JOURNAL OF MEDICINAL CHEMISTRY Year: 2022 Reference: J Med Chem. 2022 Apr 28;65(8):6070-6087. doi: 10.1021/acs.jmedchem.1c01941. Epub 2022 Apr 13. Impact factor: Publication type: Paper in international publication Authors: Alarcon, Helena; Borrell, Jose I; Bou-Petit, Elisabeth; Cano-Galietero, Marta; Estrada-Tejedor, Roger; Fuentes, Pedro; Guijarro, Pedro J; Hummer, Stefan; Munoz, Maria Jose; Ramon Y Cajal, Santiago et al. DOI: 10.1021/acs.jmedchem.1c01941
PMID: 35406600 Journal: Cancers Year: 2022 Reference: Cancers (Basel). 2022 Apr 5;14(7). pii: cancers14071828. doi: 10.3390/cancers14071828. Impact factor: Publication type: Paper in international publication Authors: Borque-Fernando, Angel; Celma, Anna; de Torres, Ines M; Esteban, Luis M; Mast, Richard; Morote, Juan; Planas, Jacques; Regis, Lucas; Santamaria, Anna; Semidey, Maria E et al. DOI: 10.3390/cancers14071828
PMID: 35366849 Journal: BMC CANCER Year: 2022 Reference: BMC Cancer. 2022 Apr 2;22(1):357. doi: 10.1186/s12885-022-09355-0. Impact factor: Publication type: Review in international publication Authors: Celma, Ana; Cuadras, Merce; de Torres, Ines M; Morote, Juan; Planas, Jacques; Regis, Lucas; Semidey, M Eugenia; Trilla, Enrique et al. DOI: 10.1186/s12885-022-09355-0
PMID: 34944822 Journal: Cancers Year: 2021 Reference: Cancers (Basel). 2021 Dec 9;13(24). pii: cancers13246202. doi: 10.3390/cancers13246202. Impact factor: 6.639 Publication type: Paper in international publication Authors: Santamaria, Anna, Rodriguez-Barrueco, Ruth, Morote, Juan, de la Cruz, Xavier, Olivan, Mireia, Garcia, Marta, Suarez, Leticia, Guiu, Marc, Gros, Laura, Mendez, Olga et al. DOI: 10.3390/cancers13246202
PMID: 33607371 Journal: EUROPEAN JOURNAL OF RADIOLOGY Year: 2021 Reference: Eur J Radiol. 2021 Apr;137:109589. doi: 10.1016/j.ejrad.2021.109589. Epub 2021 Feb 12. Impact factor: 3.528 Publication type: Paper in international publication Authors: Salazar, Aina, Planas, Jacques, Celma, Ana, Cuadras, Merce, Roche, Sarai, Mast, Richard, Morote, Juan, Trilla, Enrique, Regis, Lucas et al. DOI: 10.1016/j.ejrad.2021.109589
PMID: 32247519 Journal: Actas Urologicas Espanolas Year: 2020 Reference: Actas Urol Esp. 2020 May;44(4):245-250. doi: 10.1016/j.acuro.2019.11.006. Epub 2020 Apr 1. Impact factor: Publication type: Paper in national publication Authors: Arevalo, J; de Torres, I; Lorente, D; Meseguer, A; Morote, J; Salcedo, M T; Trilla, E et al. DOI: 10.1016/j.acuro.2019.11.006
PMID: 32203842 Journal: CANCER TREATMENT REVIEWS Year: 2020 Reference: Cancer Treat Rev. 2020 Jun;86:102000. doi: 10.1016/j.ctrv.2020.102000. Epub 2020 Mar 13. Impact factor: Publication type: Review in international publication Authors: Carles, Joan; Gonzalez, Macarena; Maldonado, Xavier; Mateo, Joaquin; Morales-Barrera, Rafael; Morote, Juan; Raventos, Carles; Serra, Ester; Suarez, Cristina; Valverde, Claudia et al. DOI: 10.1016/j.ctrv.2020.102000
PMID: 31586544 Journal: UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONS Year: 2020 Reference: Urol Oncol. 2020 Feb;38(2):40.e9-40.e15. doi: 10.1016/j.urolonc.2019.09.007. Epub 2019 Oct 2. Impact factor: Publication type: Paper in international publication Authors: Ajami, Tarek; Bonet, Xavier; Carrion, Albert; Diaz, Fernando; Dominguez, Arturo; Freixa, Roger; Huguet, Jorge; Lozano, Fernando; Mayordomo, Olga; Morote, Juan et al. DOI: 10.1016/j.urolonc.2019.09.007
PMID: 32089360 Journal: EUROPEAN UROLOGY Year: 2020 Reference: Eur Urol. 2020 May;77(5):e138-e139. doi: 10.1016/j.eururo.2020.02.010. Epub 2020 Feb 20. Impact factor: Publication type: Letter or abstract Authors: Celma, Anna; Morote, Juan; Planas, Jacques et al. DOI: 10.1016/j.eururo.2020.02.010
PMID: 30420112 Journal: Actas Urologicas Espanolas Year: 2019 Reference: Actas Urol Esp. 2019 Apr;43(3):137-142. doi: 10.1016/j.acuro.2018.07.003. Epub 2018 Nov 9. Impact factor: Publication type: Paper in national publication Authors: Celma, A; Cuadras, M; Lorente, D; Miret, E; Morote, J; Placer, J; Planas, J; Regis, L; Roche, S; Salazar, A et al. DOI: 10.1016/j.acuro.2018.07.003
PMID: 30844807 Journal: UROLOGIA INTERNATIONALIS Year: 2019 Reference: Urol Int. 2019;102(3):277-283. doi: 10.1159/000496802. Epub 2019 Mar 7. Impact factor: Publication type: Paper in international publication Authors: Carrion, Albert; Diaz, Fernando; Lozano, Fernando; Morote, Juan; Pinero, Adria; Raventos, Carles et al. DOI: 10.1159/000496802
PMID: 30922918 Journal: CANCER LETTERS Year: 2019 Reference: Cancer Lett. 2019 Jun 28;452:158-167. doi: 10.1016/j.canlet.2019.03.019. Epub 2019 Mar 25. Impact factor: Publication type: Paper in international publication Authors: Canovas, Veronica; Ciudad, Carlos J; de Torres, Ines; Felix, Alex J; Gomez, Valenti; Maggio, Valentina; Morote, Juan; Noe, Veronique; Paciucci, Rosanna; Semidey, Maria Eugenia et al. DOI: 10.1016/j.canlet.2019.03.019
PMID: 30783029 Journal: NEPHRON Year: 2019 Reference: Nephron. 2019;142(2):125-134. doi: 10.1159/000497119. Epub 2019 Feb 15. Impact factor: Publication type: Paper in international publication Authors: Cruzado, Josep M; Guiteras, Roser; Manonelles, Anna; Morote, Juan; Narvaez Barros, Alonso; Sola, Anna et al. DOI: 10.1159/000497119
PMID: 27815896 Journal: Methods in molecular biology (Clifton, N.J.) Year: 2017 Reference: Methods Mol Biol. 2017;1524:65-74. Impact factor: Publication type: Paper in international publication Authors: Dulla, Kalyan; Margalef, Anna Santamaria et al. DOI: 10.1007/978-1-4939-6603-5_4
PMID: 23455324 Journal: ONCOGENE Year: 2014 Reference: Oncogene. 2014 Feb 27;33(9):1124-34. doi: 10.1038/onc.2013.51. Epub 2013 Mar 4. Impact factor: Publication type: Paper in international publication Authors: Abasolo, I; Bermudo, R; Canovas, V; Castellon, E; Celia-Terrassa, T; Contreras, H; de Torres, I; Fernandez, P L; Fernandez, Y; Marques, N et al. DOI: 10.1038/onc.2013.51
PMID: 24636074 Journal: Actas Urologicas Espanolas Year: 2014 Reference: Actas Urol Esp. 2014 Oct;38(8):552-6. doi: 10.1016/j.acuro.2014.02.004. Epub 2014 Mar 11. Impact factor: Publication type: Paper in national publication Authors: Cantarell, C; Celma, A; Lorente, D; Moreso, F; Morote, J; Placer, J; Planas, J; Salvador, C; Seron, D; Trilla, E et al. DOI: 10.1016/j.acuro.2014.02.004
PMID: 24529539 Journal: Actas Urologicas Espanolas Year: 2014 Reference: Actas Urol Esp. 2014 May;38(4):270-5. doi: 10.1016/j.acuro.2013.10.001. Epub 2014 Feb 14. Impact factor: Publication type: Paper in national publication Authors: Bastaros, J; Celma, A; Morote, J; Placer, J; Planas, J et al. DOI: 10.1016/j.acuro.2013.10.001
PMID: 23650874 Journal: BJU INTERNATIONAL Year: 2014 Reference: BJU Int. 2014 Mar;113(3):367-75. doi: 10.1111/bju.12110. Epub 2013 Apr 12. Impact factor: Publication type: Paper in international publication Authors: Carles, Joan; Maldonado, Xavier; Morales-Barrera, Rafael; Morote, Juan; Nunez, Isaac; Planas, Jacques; Ramos, Victor; Suarez, Cristina; Valverde, Claudia et al. DOI: 10.1111/bju.12110
PMID: 23411068 Journal: Actas Urologicas Espanolas Year: 2013 Reference: Actas Urol Esp. 2013 Jun;37(6):383-6. doi: 10.1016/j.acuro.2012.11.008. Epub 2013 Feb 12. Impact factor: Publication type: Paper in national publication Authors: Lorente, D; Moreso, J; Morote, J; Seron, D; Trilla, E et al. DOI: 10.1016/j.acuro.2012.11.008
PMID: 23352434 Journal: EUROPEAN JOURNAL OF CANCER Year: 2013 Reference: Eur J Cancer. 2013 May;49(8):2034-47. doi: 10.1016/j.ejca.2012.12.020. Epub 2013 Jan 23. Impact factor: Publication type: Paper in international publication Authors: Blanco, Albert; Cuadros, Thais; de Torres, Ines; Itarte, Emilio; Lopez-Hellin, Joan; Meseguer, Anna; Messaoud, Nabil Ben; Mir, Carmen; Morote, Juan; Ramon Y Cajal, Santiago et al. DOI: 10.1016/j.ejca.2012.12.020
PMID: 23235105 Journal: UROLOGIA INTERNATIONALIS Year: 2013 Reference: Urol Int. 2013;90(1):41-4. doi: 10.1159/000342814. Epub 2012 Dec 12. Impact factor: Publication type: Paper in international publication Authors: Agreda, F; Lopez, M A; Morote, J; Placer, J; Planas, J; Salvador, C; Trilla, E et al. DOI: 10.1159/000342814
PMID: 22863066 Journal: JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY Year: 2013 Reference: J Am Acad Dermatol. 2013 Jan;68(1):73-82. doi: 10.1016/j.jaad.2012.05.029. Epub 2012 Aug 3. Impact factor: Publication type: Paper in international publication Authors: de Torres, Ines; Ferrandiz-Pulido, Carla; Garcia-Patos, Vicente; Hernandez-Losa, Javier; Lloveras, Belen; Masferrer, Emili; Mojal, Sergio; Morote, Juan; Pujol, Ramon M; Ramon Y Cajal, Santiago et al. DOI: 10.1016/j.jaad.2012.05.029
PMID: 20215818 Journal: UROLOGIA INTERNATIONALIS Year: 2010 Reference: Urol Int. 2010;84(2):153-158. Epub 2010 Mar 4. Impact factor: Publication type: Paper in international publication Authors: ; ; ; ; ; ; et al. DOI: 10.1159/000277591
PMID: 20139762 Journal: AMERICAN JOURNAL OF SURGICAL PATHOLOGY Year: 2010 Reference: Am J Surg Pathol. 2010 Mar;34(3):371-6. Impact factor: Publication type: Paper in international publication Authors: ; ; ; ; ; ; ; ; ; et al. DOI: 10.1097/PAS.0b013e3181cd385b
On World Cancer Research Day, we highlight research aimed at improving treatments for both pediatric and adult cancers through innovative techniques.
The work led by Dr. Regis demonstrates that performing robotic reconstruction after radical prostatectomy is associated with better urinary control.
A clinical trial with the prototype of the device shows that the use of this technology improves patient monitoring by nurses and reduces post-surgical complications.
