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Childhood Cancer and Blood Disorders

The research group is focused on finding new molecular therapeutic targets and biomarkers based on knowledge of the biology of paediatric tumours, leukemias and hematologic diseases. The experience of the group in recent years has permitted the identification of new molecular targets that are very close to the clinical phase. In this stage, we have consolidated collaborations with the biotechnological industry in order to develop small molecules able to inhibit pro-oncogenic processes such as invasion or proliferation, with the aim of providing patients with innovative and more specific biological evidence-based therapies.

Another line of research is based on the study of liquid biopsy to develop a system based on NGS to monitor the probability of relapses.

Furthermore, we have implemented a personalized medicine program to guide the management of patients based on the molecular alterations of their tumours

Team

Carlota Aguilera Ordoñez

Carlota Aguilera Ordoñez

Research technician
Childhood Cancer and Blood Disorders
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Gabriela Guillén Burrieza

Gabriela Guillén Burrieza

Predoctoral researcher
Childhood Cancer and Blood Disorders
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Juan Manuel López Oliva

Juan Manuel López Oliva

Research technician
Childhood Cancer and Blood Disorders
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Anna Collado Gimbert

Anna Collado Gimbert

Predoctoral researcher
Childhood Cancer and Blood Disorders
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Espinosa Lopez, Blanca

Espinosa Lopez, Blanca

Predoctoral researcher
Childhood Cancer and Blood Disorders
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Lorena Valero Arrese

Lorena Valero Arrese

Childhood Cancer and Blood Disorders
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Carlota Aguilera Ordoñez

Carlota Aguilera Ordoñez

Research technician
Childhood Cancer and Blood Disorders
Read more
Gabriela Guillén Burrieza

Gabriela Guillén Burrieza

Predoctoral researcher
Childhood Cancer and Blood Disorders
Read more
Juan Manuel López Oliva

Juan Manuel López Oliva

Research technician
Childhood Cancer and Blood Disorders
Read more
Anna Collado Gimbert

Anna Collado Gimbert

Predoctoral researcher
Childhood Cancer and Blood Disorders
Read more
Espinosa Lopez, Blanca

Espinosa Lopez, Blanca

Predoctoral researcher
Childhood Cancer and Blood Disorders
Read more
Lorena Valero Arrese

Lorena Valero Arrese

Childhood Cancer and Blood Disorders
Read more

Projects

RealiseD: Comprehensive methodological and operational approach to clinical trials in rare and ultra-rare diseases

IP: M Mar Mañu Pereira
Collaborators: -
Funding agency: EUROPEAN COMMISSION
Funding: 188587.5
Reference: REALISED
Duration: 01/01/2025 - 31/12/2029

Targeting chromatin remodelers for cancer therapy

IP: Miguel Segura Ginard
Collaborators: Maria Jose Pérez García, Marta Miera Maluenda, Adria Molero Valenzuela, Lucas Moreno Martín-Retortillo
Funding agency: Agència Gestió Ajuts Universitaris i de Recerca
Funding: 150000
Reference: 2024 PROD 00054
Duration: 02/12/2024 - 01/06/2026

HemaFAIR: Fostering F.A.I.R. Data and Standards in Rare Hematological Diseases

IP: M Mar Mañu Pereira
Collaborators: -
Funding agency: EUROPEAN COMMISSION
Funding: 221875
Reference: HEMAFAIR/EC/WIDERA-2023-ACCESS-02-01/2023/MAÑU
Duration: 01/06/2024 - 30/06/2027

ERDERA: European Rare Disease Research Alliance

IP: M Mar Mañu Pereira
Collaborators: Augusto Cesar Sao Aviles, Patricia González Ruiz, Claire Diot, Miguel Chillon Rodriguez, Simon Schwartz Navarro, Sara Isabel Reidel
Funding agency: EUROPEAN COMMISSION
Funding: 1252083.33
Reference: ERDERA/EC/HLTH-2023-DISEASE-07-01/2023/MAÑU
Duration: 01/09/2024 - 31/08/2031

Blog

News

The initiative will enable young people aged 12 to 18 to collaborate with campus researchers in the design, development and communication of scientific projects, placing patients and families at the centre of the research process.

The REACH5 study confirms that the efficacy and safety results observed in previous studies are maintained after three years of follow-up.

In-depth knowledge of tumours helps identify specific alterations and enables the provision of targeted therapies for each patient.