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Circadian Rhythms and Ageing

The group combines cutting-edge models of ageing and cancer with targeted circadian rhythm disruption and circadian-omics to define how ageing impinges upon the circadian biology of cancer. By doing so, they hope to provide a roadmap for identifying interventions that diminish cancer risk later in life, and contribute to refining and expanding the burgeoning field of cancer chronotherapy. 

Objectives: 

- Determine how ageing affects the tumourigenicity of circadian rhythm disruption 
- Characterise how ageing reshapes tumour circadian biology and circadian tumour-host interactions 
- Define the source(s) of tumour circadian biology ‘ageing’ 
- Enhance tissue circadian clocks to dissect and mitigate the ageing process

Team

Thomas Mortimer

Thomas Mortimer

Head of group
Circadian Rhythms and Ageing Laboratory
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Thomas Mortimer

Thomas Mortimer

Head of group
Circadian Rhythms and Ageing Laboratory
Read more