Skip to main content

Kidney Physiopathology

Our main scientific interest is to understand, from a multidisciplinary and translational approach, the molecular and cellular processes leading to renal dysfunction in several kidney pathologies. Specifically, our research lines are

  • to study the pathophysiology of inherited rare renal tubulopathies
  • to understand the mechanisms of kidney injury and regeneration
  • to study the development of clear cell renal cell carcinoma (ccRCC)
  • the study the impact of androgens on those processes.

We are experts on the following areas:

  • the generation of cellular disease models carrying specific gene alterations,
  • genetically modified animal models and gene therapies,
  • life-imaging high-resolution microscopy
  • working with patients’ samples for translational research.

To sum up, our research main objective is to combine –omic data from cellular and animal models with patients’ data to identify novel biomarkers and possible treatments for several renal diseases.

Team

Meritxell Ibernon Vilaró

Meritxell Ibernon Vilaró

Kidney Physiopathology
Read more
Nicolas Jose Valdes  Figueroa

Nicolas Jose Valdes Figueroa

Predoctoral researcher
Kidney Physiopathology
Read more
Raquel Arias Gonzalez

Raquel Arias Gonzalez

Kidney Physiopathology
Read more
Meritxell Ibernon Vilaró

Meritxell Ibernon Vilaró

Kidney Physiopathology
Read more
Nicolas Jose Valdes  Figueroa

Nicolas Jose Valdes Figueroa

Predoctoral researcher
Kidney Physiopathology
Read more
Raquel Arias Gonzalez

Raquel Arias Gonzalez

Kidney Physiopathology
Read more
Blog

News

Funding has been obtained for 43 projects under the calls for Health R&D&I Projects, Health Technology Development, and Independent Clinical Research

The aim of the project is to establish kidney organoids derived from patients with familial hypomagnesaemia with hypercalciuria and nephrocalcinosis, which will be essential tools for studying the disease and testing new treatments.

The work identifies variants in genes such as NFU1 that, combined with the disease-causing mutation, can accelerate kidney deterioration.