The communication is part of a study aimed at identifying the mechanisms of progression of Familial Hypomagnesemia with Hypercalciuria and Nephrocalcinosis, a rare disease that affects the kidneys.

"Patients with familial hypomagnesemia with hypercalciuria and nephrocalcinosis present miRNA profiles in urinary extracellular vesicles associated with disease progression" was the awarded work.

Researchers at the VHIR have carried out a study showing that the ClC-5 protein regulates collagen levels through the β-catenin pathway and lysosomal degradation.

The research will perform a functional analysis of phenotype-modifying genetic variants in patients affected by familial hypomagnesaemia with hypercalciuria and nephrocalcinosis (HFHNC).

The project, which has received funding from the Association for Genetic Kidney Disease Information and Research, aims to help develop new therapies for familial hypomagnesemia with hypercalciuria and nephrocalcinosis.

The association supports the Kidney Pathophysiology group at VHIR since 2015 to investigate familial hypomagnesemia with hypercalciuria and nephrocalcinosis.

Dr. Conxita Jacobs' research has been awarded in the clinical project category, while Dr. Anna Meseguer's research has been recognised in the basic research category.

Over the course of two days, experts presented the latest advances in vectors, different gene modification techniques and their transfer to clinical practice.

The researcher of the Renal Pathophysiology group at VHIR investigates the role of ClC-5 protein in the development of this rare kidney disease.

The association renews its commitment to the research of the Renal Pathophysiology group of VHIR in this rare disease that affects the kidneys.

The head of the Renal Pathophysiology group at VHIR was part of a round table on how research can help to meet the needs of patients with rare diseases.

The research describes the clinical characteristics and management of patients with this rare kidney disease in 55 hospitals in 21 European countries.

Dr. Gerard Cantero, a researcher at VHIR, is one of the authors of the study that determines the possible starting point of the development of this inflammatory bowel disease.

Researchers have generated a female and male pig model of ischemia/reperfusion renal injury and organ regeneration to study sex differences.

El donatiu permetrà continuar impulsant la recerca en hipomagnesèmia familiar del grup CIBBIM-Nanomedicina-Fisiopatologia Renal del VHIR.

Dr. Gerard Cantero, who is now a researcher at the CIBBIM-Nanomedicine - Kidney Physiopathology at VHIR, participated in the work led by CRG and IMIM.