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Jose Manuel Fort López-Barajas

Institutions of which they are part

General Surgery
Vall Hebron Institut de Recerca
Endocrine, Metabolic, and Bariatric Surgery
General Hospital

Research lines

Endocrine, bariatric and metabolic surgery

123 Research focus The endocrine, bariatric and metabolic surgery research group seeks to improve knowledge of the diseases included in this general surgery subspecialty. Therefore, knowledge of aspects of relationships with endocrine diseases like thyroid disease, adrenal and obesity are part of the interest of its members. Sub-lines: 1. Surgery for morbid obesity: 1. Longitudinal expression analyses of genes related to lipid metabolism within the liver, visceral and subcutaneous adipose, gastric mucosa and intestine tissues from morbidly obese patients undergoing bariatric surgery; Evaluation of the associated comorbidities; 2. Analysis of sexual dysfunction in patients with morbid obesity; 3. Pressure changes evaluation in gastric sleeve and its possible implications; 4. Expression of tumour growth factors in morbidly obese patients (tumour necrosis factor (TNF)-a, granulocyte-macrophage Colony-Stimulating Factor, Interferon-?, interleukin (IL)-1b, IL-2, IL-4, IL -5, IL-6, IL-8, IL-10, vascular endothelial growth factor, hepatocyte growth factor, TNF-receptors I and II (TNF-RI, TNF-RII), death receptor 5, Leptin and adiponectin), and study of their evolution with changes related to weight loss. 2. Metabolic Surgery: Fat features’ changes in morbidly obese patients. 3. Thyroid gland surgery: 1. Utility of the neuronal neuromonitorization during in thyroid surgery; 2. Cervical ultrasound done by the surgeon: does it bring something?; 3. Utility of the cervicoscopy in the pathology of thyroid and parathyroid; 4. Thyroid cancer; 5. Evaluation and clinical validity of the selective sentinel node biopsy in the diagnosis of extension of papillary thyroid cancer; 6. rTSH mRNA usefulness in the diagnosis of follicular thyroid carcinoma. 4. Parathyroid glands surgery: Analysis of the usefulness of determining PTH concentrations intra-operatively in hyperparathyroidism treatment. 5. Adrenal gland surgery: Adrenal metastases treatment (techniques and indications). 6. Robotic Surgery: 1. Applicability and safety of robotic surgery in obese pathology (study carried out in collaboration with the Colorectal Surgery Unit and the Gynecology, Urology and Pediatric Surgery Divisions, and coordinated by the HUVH CAHTA). 7. Transumbilical surgery: Transumbulical surgery in acute appendicitis (multicenter study conducted in collaboration with the Department of Surgery Faculty of Medicine of Istanbul, Turkey, and the General Surgery Division of the University Hospital of Cairo, Egypt). 8. Transumbilical cholecystectomy: Multicenter study conducted in conjunction with the Department of Surgery Faculty of Medicine of Istanbul (Turkey).

IP: Jose Manuel Fort López-Barajas

Projects

Función de la Sex Hormone-Binding Globulin en el Tejido Adiposo: Caracterización de la Expresión, Regulación e Implicaciones Terapéuticas.

IP: David Martinez Selva
Collaborators: Jose Manuel Fort López-Barajas, Lorena Ramos Pérez
Funding agency: Instituto de Salud Carlos III
Funding: 177265
Reference: PI15/00823
Duration: 01/01/2016 - 30/09/2019

Evaluación y validación clínica de la biopsia selectiva del ganglio centinela en el diagnóstico de extensión ganglionar del cáncer papilar de tiroides

IP: Oscar González López
Collaborators: Joan Castell Conesa, Amparo García Burillo, Carles Zafon Llopis, Jose Manuel Fort López-Barajas, Xavier Serres Créixams, Ramón Vilallonga Puy
Funding agency: Instituto de Salud Carlos III
Funding: 41436
Reference: PI09/90440
Duration: 01/01/2010 - 31/12/2012

Síndrome de apneas-hipopneas del sueño en mujeres premenopáusicas con obesidad mórbida incluidas en un programa de cirugía bariátrica. Influencia sobre los factores de riesgo cardiovascular: activación simpática, inflamación y resistencia a la insulina

IP: -
Collaborators: Odile Romero Santo-Tomas, Jose Manuel Fort López-Barajas, Gabriel Sampol Rubio
Funding agency: Instituto de Salud Carlos III
Funding: 25410
Reference: PI060476
Duration: 01/01/2007 - 30/12/2009

Co -morbilidades asociadas a la obesidad mórbida y evolución con la cirugía bariatrica: alteraciones del metabolismo lipídico, esteatosis hepática, trombofilia y factores de saciedad.

IP: -
Collaborators: Victor Manuel Vargas Blasco, Jose Manuel Fort López-Barajas
Funding agency: Instituto de Salud Carlos III
Funding: 25300
Reference: PI030042
Duration: 01/01/2003 - 31/05/2007

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