This is a multicentre study supported by the Systemic Autoimmune Diseases Group (GEAS) from the Spanish Internal Medicine Society (SEMI). The aim of the study is to describe the different clinical forms of presentation of these diseases, the response to the conventional treatment of the different subtypes of vasculitides, and the prognostic factors and survival in our country. This study includes 17 Hospitals from Spain with a cohort of 300 patients. We are the study coordinator Centre.

Cardiac involvement is one of the most important causes of dead in EGPE. The aim of this study is to investigate the prevalence of silent cardiac involvement in patients with EGPE, and if some chemotaxins (eotaxins 1, 2 and 3) may play a key role in its development, in order to establish an early tretament.