Clinical Pharmacology

The aim of our group is to investigate the use of medicines and evaluate its benefit/risk relationship in usual clinical practice. Our group coordinates the Catalan centre of the Spanish System of Pharmacovigilance. Research activities on pharmacology and pharmacoepidemiology are coupled with undergraduate teaching at the Autonomous University of Barcelona Medical School, training of specialists in clinical pharmacology, and continuous education of health professionals on therapeutics.

The group is a Special Group of Research recognized by AGAUR GenCat. It is a partner of “The European Consortium “EU PE&PV Network” (European Pharmacoepidemiology and Pharmacovigilance Network)” and it is part of the European Network of Centres for Pharmacoepidemiology and Pharmacovigilance (ENCePP). It gives institutional support to the Clinical Research Ethical Committee of the University hospital Vall d’Hebron (UHVH), the Drug and Pharmacotherapeutic Committee of the UHVH, and also to the Drug and Pharmacotherapeutic Committee of the Institut Català de la Salut.

Team

Montse Bosch Ferrer

Clinical Pharmacology
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Bellas Fernandez, Lucia

Predoctoral researcher
Clinical Pharmacology
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Camacho Arteaga, Lina Fernanda

Research technician
Clinical Pharmacology
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Emilie Anderssen Nordahl

Main researcher
Clinical Pharmacology
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Mata Ley, Suyvan Esther

Predoctoral researcher
Clinical Pharmacology
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Alba Vimes Fortis

Research assistant
Clinical Pharmacology
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Montse Bosch Ferrer

Clinical Pharmacology
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Bellas Fernandez, Lucia

Predoctoral researcher
Clinical Pharmacology
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Camacho Arteaga, Lina Fernanda

Research technician
Clinical Pharmacology
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Emilie Anderssen Nordahl

Main researcher
Clinical Pharmacology
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Mata Ley, Suyvan Esther

Predoctoral researcher
Clinical Pharmacology
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Alba Vimes Fortis

Research assistant
Clinical Pharmacology
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Research lines

PROTECT (Pharmacoepidemiological Research on Outcome of Therapeutics by a European ConsorTium

The goal of this project is to strengthen the monitoring of benefit-risk of medicines in Europe by developing innovative methods that will enhance the early detection and assessment of adverse drug reaction from different data sources (clinical trials, spontaneous reporting and observational studies). Our group is responsible for working on the use of national drug utilisation data. The specific tasks are to build and update an inventory of data sources on the consumption of the medicines of interest, to evaluate and disseminate methodologies for drug utilisation studies in order to estimate the potential public health impact of adverse drug reactions.

IP: PROTECT (Pharmacoepidemiological Research on Outcome of Therapeutics by a European ConsorTium, PROTECT (Pharmacoepidemiological Research on Outcome of Therapeutics by a European ConsorTium

Risk of blood dyscrasias associated with the use of medicines

IP: -

Study of drug-induced liver disease

IP: -

Projects

Aquest any no hi ha projectes actius.

Publications

Use of antibiotics in the early COVID-19 pandemic in Poland, the Netherlands and Spain, from erraticism to (more) logic.

PMID: 39017693
Journal: EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY
Year: 2024
Reference: Eur J Clin Pharmacol. 2024 Jul 17. doi: 10.1007/s00228-024-03726-1.
Impact factor:
Publication type: Paper in international publication
Authors: Ballarin, Maria Elena; de Groot, Mark; Gardarsdottir, Helga; Kwa, Marcel; Leufkens, Hubert; Opalska, Aleksandra; Sabate, Monica; Wojkowska-Mach, Jadwiga et al.
DOI: 10.1007/s00228-024-03726-1

Falls in hospitalized older adults and the use of fall risk-increasing drugs and anticholinergic medications in Colombia: a case?control study.

PMID: 39021833
Journal: Frontiers in Pharmacology
Year: 2024
Reference: Front Pharmacol. 2024 Jul 3;15:1369200. doi: 10.3389/fphar.2024.1369200. eCollection 2024.
Impact factor:
Publication type: Paper in international publication
Authors: Camacho-Arteaga, Lina; Machado-Alba, Jorge E; Machado-Duque, Manuel E; Sabate, Monica; Vidal-Guitart, Xavier et al.
DOI: 10.3389/fphar.2024.1369200

Women's health in focus: Real-world data on valproate prescriptions during pregnancy - a cohort study in Catalonia (Spain).

PMID: 39134441
Journal: BMJ Open
Year: 2024
Reference: BMJ Open. 2024 Aug 12;14(8):e085167. doi: 10.1136/bmjopen-2024-085167.
Impact factor:
Publication type: Paper in international publication
Authors: Aguilera, Cristina; Agusti, Antonia; Bellas, Lucia; Camacho-Arteaga, Lina; Giner-Soriano, Maria; Prats-Uribe, Albert; Vedia Urgell, Cristina et al.
DOI: 10.1136/bmjopen-2024-085167

Correction to: Use of antibiotics in the early COVID-19 pandemic in Poland, the Netherlands and Spain, from erraticism to (more) logic.

PMID: 39168875
Journal: EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY
Year: 2024
Reference: Eur J Clin Pharmacol. 2024 Aug 22. doi: 10.1007/s00228-024-03742-1.
Impact factor:
Publication type: Other (letters to the editor, abstracts, corrigendum, etc.)
Authors: Ballarin, Maria Elena; de Groot, Mark; Gardarsdottir, Helga; Kwa, Marcel; Leufkens, Hubert; Opalska, Aleksandra; Sabate, Monica; Wojkowska-Mach, Jadwiga et al.
DOI: 10.1007/s00228-024-03742-1

Impact of the 2018 revised Pregnancy Prevention Programme by the European Medicines Agency on the use of oral retinoids in females of childbearing age in Denmark, Italy, Netherlands, and Spain: an interrupted time series analysis.

PMID: 37663263
Journal: Frontiers in Pharmacology
Year: 2023
Reference: Front Pharmacol. 2023 Aug 17;14:1207976. doi: 10.3389/fphar.2023.1207976. eCollection 2023.
Impact factor:
Publication type: Paper in international publication
Authors: Abtahi, Shahab; Alsina, Ema; Andersen, Morten; Ballarin, Elena; Bartolini, Claudia; Duran, Carlos E; Gamba, Magdalena; Garcia-Poza, Patricia; Garcia-Sempere, Anibal; Gini, Rosa et al.
DOI: 10.3389/fphar.2023.1207976

The challenges of access to innovative medicines with limited evidence in the European Union.

PMID: 37719853
Journal: Frontiers in Pharmacology
Year: 2023
Reference: Front Pharmacol. 2023 Aug 31;14:1215431. doi: 10.3389/fphar.2023.1215431. eCollection 2023.
Impact factor:
Publication type: Review in international publication
Authors: Agusti, Antonia; Agusti, Antonia; Agusti, Antonia; Pontes, Caridad; Vallano, Antonio; Vallano, Antonio et al.
DOI: 10.3389/fphar.2023.1215431

Long-term survival after cardiac arrest in patients undergoing emergent coronary angiography.

PMID: 37793964
Journal: Cardiovascular revascularization medicine : includ
Year: 2023
Reference: Cardiovasc Revasc Med. 2023 Sep 28:S1553-8389(23)00827-8. doi: 10.1016/j.carrev.2023.09.008.
Impact factor:
Publication type: Paper in international publication
Authors: Abdul-Jawad, Omar; Abdul-Jawad, Omar; Andrea, Rut; Angiolillo, Dominick J; Brugaletta, Salvatore; Cardenas, Merida; Carrillo, Xavier; Cepas-Guillen, Pedro Luis; de Diego, Oriol; Freixa, Xavier et al.
DOI: 10.1016/j.carrev.2023.09.008

Safety and immunogenicity of the protein-based PHH-1V compared to BNT162b2 as a heterologous SARS-CoV-2 booster vaccine in adults vaccinated against COVID-19: a multicentre, randomised, double-blind, non-inferiority phase IIb trial.

PMID: 37131861
Journal: The Lancet regional health. Europe
Year: 2023
Reference: Lancet Reg Health Eur. 2023 May;28:100613. doi: 10.1016/j.lanepe.2023.100613. Epub 2023 Apr 14.
Impact factor:
Publication type: Paper in international publication
Authors: Alvarez-Mon, Melchor; Anagua, Jesse Omar; Arana-Arri, Eunate; Arribas, Jose R; Bailon, Lucia; Barreiro, Antonio; Benet, Susana; Blanch-Lombarte, Oscar; Blanco, Julia; Borobia, Alberto M et al.
DOI: 10.1016/j.lanepe.2023.100613

Management of Cancer-Associated Myositis.

PMID: 36313478
Journal: Current treatment options in rheumatology
Year: 2022
Reference: Curr Treatm Opt Rheumatol. 2022;8(4):91-104. doi: 10.1007/s40674-022-00197-2. Epub 2022 Oct 21.
Impact factor:
Publication type: Review in international publication
Authors: Agusti, Antonia; Alvarado-Cardenas, Marcelo; Gil-Vila, Albert; Lostes, Julia; Pinal-Fernandez, Iago; Riera-Arnau, Judit; Ros, Javier; Ros, Javier; Selva-O'Callaghan, Albert; Trallero-Araguas, Ernesto et al.
DOI: 10.1007/s40674-022-00197-2

Incidence and characteristics of adverse drug reactions in a cohort of patients treated with PD-1/PD-L1 inhibitors in real-world practice.

PMID: 36072949
Journal: Frontiers in Medicine
Year: 2022
Reference: Front Med (Lausanne). 2022 Aug 22;9:891179. doi: 10.3389/fmed.2022.891179. eCollection 2022.
Impact factor:
Publication type: Paper in international publication
Authors: Agusti Escasany, Antonia; Brana, Irene; Carles Galceran, Joan; Carreras Soler, Maria-Josep; Farriols Danes, Anna; Felip, Enriqueta; Garcia Dolade, Nuria; Morales Barrera, Rafael; Munoz-Couselo, Eva; Perez Esquirol, Eulalia et al.
DOI: 10.3389/fmed.2022.891179

Reactogenicity to the mRNA-1273 Booster According to Previous mRNA COVID-19 Vaccination.

PMID: 36016105
Journal: Vaccines
Year: 2022
Reference: Vaccines (Basel). 2022 Jul 29;10(8). pii: vaccines10081217. doi: 10.3390/vaccines10081217.
Impact factor:
Publication type: Paper in international publication
Authors: Aguilera, Cristina; Agusti, Antonia; Armadans, Lluis; Borras-Bermejo, Blanca; Campins, Magda; Cossio-Gil, Yolima; Martinez-Gomez, Xavier; Otero, Susana; Pares-Badell, Oleguer; Pinos, Laia et al.
DOI: 10.3390/vaccines10081217

Humoral and cellular response in convalescent COVID-19 lupus patients.

PMID: 35962159
Journal: Scientific Reports
Year: 2022
Reference: Sci Rep. 2022 Aug 12;12(1):13787. doi: 10.1038/s41598-022-17334-5.
Impact factor:
Publication type: Paper in international publication
Authors: Cortes-Hernandez, Josefina; Domingo, Sandra; Sole, Cristina; Vidal, Xavier et al.
DOI: 10.1038/s41598-022-17334-5

Adverse Drug Reactions in Pediatric Oncohematology: A Systematic Review.

PMID: 35185536
Journal: Frontiers in Pharmacology
Year: 2021
Reference: Front Pharmacol. 2022 Feb 3;12:777498. doi: 10.3389/fphar.2021.777498. eCollection 2021.
Impact factor:
Publication type: Review in international publication
Authors: Agusti, Antonia; Amaro-Hosey, Kristopher; Danes, Immaculada et al.
DOI: 10.3389/fphar.2021.777498

Real-World Management and Clinical Outcomes of Stroke Survivors With Atrial Fibrillation: A Population-Based Cohort in Spain.

PMID: 34966283
Journal: Frontiers in Pharmacology
Year: 2021
Reference: Front Pharmacol. 2021 Dec 13;12:789783. doi: 10.3389/fphar.2021.789783. eCollection 2021.
Impact factor:
Publication type: Paper in international publication
Authors: Bejarano-Quisoboni, Daniel; Hurtado, Isabel; Riera-Arnau, Judit; Rodriguez-Bernal, Clara L; Sanchez-Saez, Francisco; Sanfelix-Gimeno, Gabriel et al.
DOI: 10.3389/fphar.2021.789783

Local and Systemic Adverse Reactions to mRNA COVID-19 Vaccines Comparing Two Vaccine Types and Occurrence of Previous COVID-19 Infection.

PMID: 34960209
Journal: Vaccines
Year: 2021
Reference: Vaccines (Basel). 2021 Dec 10;9(12). pii: vaccines9121463. doi: 10.3390/vaccines9121463.
Impact factor:
Publication type: Paper in international publication
Authors: Aguilera, Cristina; Agusti, Antonia; Borras-Bermejo, Blanca; Campins, Magda; Cossio-Gil, Yolima; Martinez-Gomez, Xavier; Otero-Romero, Susana; Pares-Badell, Oleguer; Pinos, Laia; Rodrigo-Pendas, Jose Angel et al.
DOI: 10.3390/vaccines9121463

Methodological Characteristics of Clinical Trials Supporting the Marketing Authorisation of Advanced Therapies in the European Union.

PMID: 34916948
Journal: Frontiers in Pharmacology
Year: 2021
Reference: Front Pharmacol. 2021 Nov 29;12:773712. doi: 10.3389/fphar.2021.773712. eCollection 2021.
Impact factor:
Publication type: Review in international publication
Authors: Agusti, Antonia; Iglesias-Lopez, Carolina; Obach, Merce; Vallano, Antonio et al.
DOI: 10.3389/fphar.2021.773712

Genome-Wide Association Study of Metamizole-Induced Agranulocytosis in European Populations.

PMID: 33138277
Journal: Genes
Year: 2020
Reference: Genes (Basel). 2020 Oct 29;11(11). pii: genes11111275. doi: 10.3390/genes11111275.
Impact factor:
Publication type: Paper in international publication
Authors: Amstutz, Ursula; Bonadies, Nicolas; Carvajal, Alfonso; Cismaru, Anca Liliana; Eriksson, Niclas; EuDAC Collaborators; Hallberg, Par; Haschke, Manuel; Ibanez, Luisa; Krahenbuhl, Stephan et al.
DOI: 10.3390/genes11111275

High-Throughput Sequencing to Investigate Associations Between HLA Genes and Metamizole-Induced Agranulocytosis.

PMID: 32973882
Journal: Frontiers in Genetics
Year: 2020
Reference: Front Genet. 2020 Aug 21;11:951. doi: 10.3389/fgene.2020.00951. eCollection 2020.
Impact factor:
Publication type: Paper in international publication
Authors: Amstutz, Ursula; Bonadies, Nicolas; Cismaru, Anca Liliana; Grimm, Livia; Hallberg, Par; Haschke, Manuel; Ibanez, Luisa; Kreutz, Reinhold; Largiader, Carlo R; Liakoni, Evangelia et al.
DOI: 10.3389/fgene.2020.00951

Telemonitoring in Chronic Pain Management Using Smartphone Apps: A Randomized Controlled Trial Comparing Usual Assessment against App-Based Monitoring with and without Clinical Alarms.

PMID: 32916983
Journal: International Journal of Environmental Research and Public Health
Year: 2020
Reference: Int J Environ Res Public Health. 2020 Sep 9;17(18). pii: ijerph17186568. doi: 10.3390/ijerph17186568.
Impact factor:
Publication type: Paper in international publication
Authors: Castilla, Diana; Garcia-Palacios, Azucena; Medel, Javier; Mesas, Angela; Server, Anna; Suso-Ribera, Carlos; Zaragoza, Irene et al.
DOI: 10.3390/ijerph17186568

Corrigendum: Influence of Polymorphisms Involved in Platelet Activation and Inflammatory Response on Aspirin-Related Upper Gastrointestinal Bleeding: A Case-Control Study.

PMID: 32765275
Journal: Frontiers in Pharmacology
Year: 2020
Reference: Front Pharmacol. 2020 Jul 17;11:1072. doi: 10.3389/fphar.2020.01072. eCollection 2020.
Impact factor:
Publication type: Letter or abstract
Authors: Aguirre, Carmelo; Dominguez-Munoz, J Enrique; Figueiras, Adolfo; Ibanez, Luisa; Ibarra-Garcia, Eguzkine; Macias-Garcia, Fernando; Mallah, Narmeen; Martin-Arias, Luis; Palacios-Zabalza, Itziar; Pineiro-Lamas, Maria et al.
DOI: 10.3389/fphar.2020.01072

Lactic acidosis associated with metformin in patients with moderate to severe chronic kidney disease: study protocol for a multicenter population-based case-control study using health databases.

PMID: 31146690
Journal: BMC Nephrology
Year: 2019
Reference: BMC Nephrol. 2019 May 30;20(1):193. doi: 10.1186/s12882-019-1389-8.
Impact factor:
Publication type: Paper in international publication
Authors: Aguilar, Monica; Aguilera, Cristina; Alonso, Virginia; Antonijoan, Rosa; Avila, Monica; Avila, Monica; Barriocanal, Ana Maria; Corbella, Xavier; Delgado, Claudia E; Estevez, Jose C et al.
DOI: 10.1186/s12882-019-1389-8

Rivaroxaban Versus Vitamin K Antagonist in Antiphospholipid Syndrome: A Randomized Noninferiority Trial.

PMID: 31610549
Journal: ANNALS OF INTERNAL MEDICINE
Year: 2019
Reference: Ann Intern Med. 2019 Nov 19;171(10):685-694. doi: 10.7326/M19-0291. Epub 2019 Oct 15.
Impact factor:
Publication type: Paper in international publication
Authors: Castro-Salomo, Antoni; Cortes-Hernandez, Josefina; Cuquet-Pedragosa, Jordi; Mauri-Plana, Montserrat; Ordi-Ros, Josep; Ortiz-Santamaria, Vera; Perez-Conesa, Mercedes; Riera-Mestre, Antoni; Saez-Comet, Luis; Sole, Cristina et al.
DOI: 10.7326/M19-0291

Regulatory Framework for Advanced Therapy Medicinal Products in Europe and United States.

PMID: 31543814
Journal: Frontiers in Pharmacology
Year: 2019
Reference: Front Pharmacol. 2019 Aug 30;10:921. doi: 10.3389/fphar.2019.00921. eCollection 2019.
Impact factor:
Publication type: Paper in international publication
Authors: Agusti, Antonia; Iglesias-Lopez, Carolina; Obach, Merce; Vallano, Antonio et al.
DOI: 10.3389/fphar.2019.00921

Urinary Neuropilin-1: A Predictive Biomarker for Renal Outcome in Lupus Nephritis.

PMID: 31533337
Journal: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Year: 2019
Reference: Int J Mol Sci. 2019 Sep 17;20(18). pii: ijms20184601. doi: 10.3390/ijms20184601.
Impact factor:
Publication type: Paper in international publication
Authors: Cortes-Hernandez, Josefina; Hotter, Georgina; Moline, Teresa; Ordi-Ros, Josep; Sanchis, Mireia; Sola, Anna; Sole, Cristina; Torres-Salido, Maria Teresa; Vidal, Marta; Vidal, Xavier et al.
DOI: 10.3390/ijms20184601

Gabapentin and Pregabalin and Risk of Atrial Fibrillation in the Elderly: A Population-Based Cohort Study in an Electronic Prescription Database.

PMID: 29956217
Journal: DRUG SAFETY
Year: 2018
Reference: Drug Saf. 2018 Dec;41(12):1325-1331. doi: 10.1007/s40264-018-0695-6.
Impact factor:
Publication type: Paper in international publication
Authors: Asensio, Carmen; Carbonell, Pere; Escoda, Nuria; Laporte, Joan-Ramon; Lopez, Pilar; Ortiz de Landaluce, Leticia et al.
DOI: 10.1007/s40264-018-0695-6

Prevalence of use of antipsychotic drugs in the elderly in Catalonia.

PMID: 29796874
Journal: EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY
Year: 2018
Reference: Eur J Clin Pharmacol. 2018 Sep;74(9):1185-1186. doi: 10.1007/s00228-018-2469-6. Epub 2018 May 23.
Impact factor:
Publication type: Letter or abstract
Authors: Asensio, Carmen; Carbonell, Pere; Escoda, Nuria; Laporte, Joan-Ramon; Lopez, Pilar; Sabate, Monica et al.
DOI: 10.1007/s00228-018-2469-6

Sulfasalazine-induced agranulocytosis is associated with the human leukocyte antigen locus.

PMID: 28762467
Journal: CLINICAL PHARMACOLOGY & THERAPEUTICS
Year: 2018
Reference: Clin Pharmacol Ther. 2018 May;103(5):843-853. doi: 10.1002/cpt.805. Epub 2017 Sep 28.
Impact factor:
Publication type: Paper in international publication
Authors: Axelsson, Tomas; Bengtsson, Mats; Bondon-Guitton, Emmanuelle; Carvajal, Alfonso; Eriksson, Niclas; Hallberg, Par; Ibanez, Luisa; Kohnke, Hugo; Kreutz, Reinhold; Lucena, M Isabel et al.
DOI: 10.1002/cpt.805

[Biological and biosimilar drugs: Clarifying concepts].

PMID: 29605234
Journal: Atencion Primaria
Year: 2018
Reference: Aten Primaria. 2018 Jun - Jul;50(6):323-324. doi: 10.1016/j.aprim.2018.01.002. Epub 2018 Mar 28.
Impact factor:
Publication type: Editorail in international publication
Authors: Asensio Ostos, Carmen; Rodriguez Cumplido, Dolores et al.
DOI: 10.1016/j.aprim.2018.01.002

[Characteristics of potentially inappropriate prescribing of drugs in elderly polypathological patients].

PMID: 27486035
Journal: Gaceta Sanitaria
Year: 2017
Reference: Gac Sanit. 2017 Jul - Aug;31(4):327-331. doi: 10.1016/j.gaceta.2016.06.013. Epub 2016 Jul 30.
Impact factor:
Publication type: Paper in national publication
Authors: Agusti, Antonia; Formiga, Francesc; Garcia, Juana; Gomez Hernandez, Mercedes; Lopez-Soto, Alfonso; Ramirez-Duque, Nieves; Rivas-Cobas, Paula Carlota; San-Jose, Antonio; Torres, Olga H; Vidal, Xavier et al.
DOI: 10.1016/j.gaceta.2016.06.013

Adaptive Pathways: Possible Next Steps for Payers in Preparation for Their Potential Implementation.

PMID: 28878667
Journal: Frontiers in Pharmacology
Year: 2017
Reference: Front Pharmacol. 2017 Aug 23;8:497. doi: 10.3389/fphar.2017.00497. eCollection 2017.
Impact factor:
Publication type: Review in national publication
Authors: Arickx, Francis; Bezmelnitsyna, Liudmila; Bochenek, Tomasz; Bucsics, Anna; Bybau, Alexander; Diogene, Eduardo; Eriksson, Irene; Ermisch, Michael; Furst, Jurij; Gad, Mohamed et al.
DOI: 10.3389/fphar.2017.00497

A new risk of bias checklist applicable to randomized trials, observational studies and systematic reviews was developed and validated to be used for systematic reviews focusing on drug adverse events.

PMID: 28487158
Journal: JOURNAL OF CLINICAL EPIDEMIOLOGY
Year: 2017
Reference: J Clin Epidemiol. 2017 Jun;86:168-175. doi: 10.1016/j.jclinepi.2017.04.023. Epub 2017 May 6.
Impact factor:
Publication type: Paper in international publication
Authors: Ballarin, Elena; Berkemeyer, Shoma; Castells, Xavier; Driot, Damien; Faillie, Jean-Luc; Ferrer, Pili; Gouverneur, Amandine; Huerta, Consuelo; Ibanez, Luisa; Martinez-Zapata, Maria Jose et al.
DOI: 10.1016/j.jclinepi.2017.04.023

Enteric-coated mycophenolate sodium versus azathioprine in patients with active systemic lupus erythematosus: a randomised clinical trial.

PMID: 28450313
Journal: ANNALS OF THE RHEUMATIC DISEASES
Year: 2017
Reference: Ann Rheum Dis. 2017 Sep;76(9):1575-1582. doi: 10.1136/annrheumdis-2016-210882. Epub 2017 Apr 27.
Impact factor:
Publication type: Paper in international publication
Authors: Castro Salomo, Antoni; Cortes-Hernandez, Josefina; Cuquet Pedragosa, Jordi; Mauri Plana, Montserrat; Mitjavila, Francesca; Ordi-Ros, Josep; Ortiz-Santamaria, Vera; Perez-Conesa, Mercedes; Saez-Comet, Luis; Vidal, Xavier et al.
DOI: 10.1136/annrheumdis-2016-210882

Multi-centre, multi-database studies with common protocols: lessons learnt from the IMI PROTECT project.

PMID: 27038361
Journal: PHARMACOEPIDEMIOLOGY AND DRUG SAFETY
Year: 2016
Reference: Pharmacoepidemiol Drug Saf. 2016 Mar;25 Suppl 1:156-65. doi: 10.1002/pds.3968.
Impact factor:
Publication type: Paper in international publication
Authors: de Groot, Mark C H; Grimaldi, Lamiae; Groenwold, Rolf H H; Ibanez, Luisa; Klungel, Olaf H; Kurz, Xavier; Reynolds, Robert F; Schlienger, Raymond G; Tcherny-Lessenot, Stephanie et al.
DOI: 10.1002/pds.3968

Coping is Important for Spouses Too: Impulsive Coping Moderates the Relationship Between Spouses' Perception of the Patients' Pain Intensity and Spouses' Physical Health.

PMID: 26710226
Journal: CLINICAL JOURNAL OF PAIN
Year: 2016
Reference: Clin J Pain. 2016 Sep;32(9):755-62. doi: 10.1097/AJP.0000000000000328.
Impact factor:
Publication type: Paper in international publication
Authors: Ribera-Canudas, M Victoria; Suso-Ribera, Carlos; Yakobov, Esther et al.
DOI: 10.1097/AJP.0000000000000328

Polypharmacy in elderly people with diabetes admitted to hospital.

PMID: 26607825
Journal: ACTA DIABETOLOGICA
Year: 2016
Reference: Acta Diabetol. 2016 Oct;53(5):857-8. doi: 10.1007/s00592-015-0818-9. Epub 2015 Nov 25.
Impact factor:
Publication type: Letter or abstract
Authors: Agusti, Antonia; Formiga, Francesc; Jose, Antonio San et al.
DOI: 10.1007/s00592-015-0818-9

Inappropriate prescribing in elderly people with diabetes admitted to hospital.

PMID: 26333026
Journal: DIABETIC MEDICINE
Year: 2016
Reference: Diabet Med. 2016 May;33(5):655-62. doi: 10.1111/dme.12894. Epub 2015 Oct 18.
Impact factor:
Publication type: Paper in international publication
Authors: Aguilera, Cristina; Agusti, A; Ballarin, Elena; Ballesteros, Isabel; Barbe, J; Bocanegra, Carmen Perez; Bosch, Xavier; Cabot, Carme; Chivite, D; Cobas, Paula-Carlota Rivas et al.
DOI: 10.1111/dme.12894

Dronedarone and renal impairment: evaluation of Spanish postmarketing reports and review of literature.

PMID: 25967281
Journal: EXPERT OPIN DRUG SAF
Year: 2015
Reference: Expert Opin Drug Saf. 2015 Jun;14(6):807-13. doi: 10.1517/14740338.2015.1036857. Epub 2015 May 12.
Impact factor:
Publication type: Review in national publication
Authors: Cereza, Gloria; Figueras, Albert; Tarapues, Monica et al.
DOI: 10.1517/14740338.2015.1036857

Association of individual non-steroidal anti-inflammatory drugs and chronic kidney disease: a population-based case control study.

PMID: 25880729
Journal: PLOS ONE
Year: 2015
Reference: PLoS One. 2015 Apr 16;10(4):e0122899. doi: 10.1371/journal.pone.0122899. eCollection 2015.
Impact factor:
Publication type: Paper in international publication
Authors: Arcoraci, Vincenzo; Fontana, Andrea; Giorgianni, Francesco; Ibanez, Luisa; Ingrasciotta, Ylenia; Perrotta, Margherita; Santangelo, Antonio; Santoro, Domenico; Sultana, Janet; Tari, Daniele Ugo et al.
DOI: 10.1371/journal.pone.0122899

Quality indicators as a tool in improving the introduction of new medicines.

PMID: 25052464
Journal: BASIC CLIN PHARMACOL
Year: 2015
Reference: Basic Clin Pharmacol Toxicol. 2015 Feb;116(2):146-57. doi: 10.1111/bcpt.12295. Epub 2014 Sep 19.
Impact factor:
Publication type: Paper in international publication
Authors: Campbell, Stephen M; Diogene, Eduardo; Furst, Jurij; Godman, Brian; Gustafsson, Lars L; MacBride-Stewart, Sean; Malmstrom, Rickard E; Pedersen, Hanne; Selke, Gisbert; van Woerkom, Menno et al.
DOI: 10.1111/bcpt.12295

Sales of macrolides, lincosamides, streptogramins, and amoxicillin/clavulanate in the in- and outpatient setting in 10 European countries, 2007-2010.

PMID: 26543747
Journal: SpringerPlus
Year: 2015
Reference: Springerplus. 2015 Oct 15;4:612. doi: 10.1186/s40064-015-1398-4. eCollection 2015.
Impact factor:
Publication type: Paper in international publication
Authors: Ballarin, Elena; Ferrer, Pili; Fortuny, Joan; Ibanez, Luisa; Laporte, Joan-Ramon; Rottenkolber, Marietta; Sabate, Monica; Schmiedl, Sven et al.
DOI: 10.1186/s40064-015-1398-4

Antiepileptic drugs and suicide: a systematic review of adverse effects.

PMID: 24401764
Journal: NEUROEPIDEMIOLOGY
Year: 2014
Reference: Neuroepidemiology. 2014;42(2):107-20. doi: 10.1159/000356807. Epub 2014 Jan 3.
Impact factor:
Publication type: Paper in international publication
Authors: Amelio, Justyna; Ballarin, Elena; Ferrer, Pili; Hasford, Joerg; Ibanez, Luisa; Rottenkolber, Marietta; Sabate, Monica; Schmiedl, Sven; Vidal, Xavier et al.
DOI: 10.1159/000356807

[Off-label drug use in hospitals].

PMID: 24183116
Journal: MEDICINA CLINICA
Year: 2014
Reference: Med Clin (Barc). 2014 Oct 7;143(7):327-8. doi: 10.1016/j.medcli.2013.09.003. Epub 2013 Oct 30.
Impact factor:
Publication type: Letter whit IF
Authors: Alerany, Carmen; Danes, Imma; Ferrer, Anna; Vallano, Antoni et al.
DOI: 10.1016/j.medcli.2013.09.003

Utilisation and off-label prescriptions of respiratory drugs in children.

PMID: 25180704
Journal: PLoS One
Year: 2014
Reference: PLoS One. 2014 Sep 2;9(9):e105110. doi: 10.1371/journal.pone.0105110. eCollection 2014.
Impact factor:
Publication type: Paper in international publication
Authors: Fischer, Rainald; Fortuny, Joan; Gerlach, Roman; Hasford, Joerg; Ibanez, Luisa; Klungel, Olaf H; Reynolds, Robert; Rottenkolber, Marietta; Schmiedl, Sven; Tauscher, Martin et al.
DOI: 10.1371/journal.pone.0105110

Dabigatran - a continuing exemplar case history demonstrating the need for comprehensive models to optimize the utilization of new drugs.

PMID: 24959145
Journal: FRONT PHARMACOL
Year: 2014
Reference: Front Pharmacol. 2014 Jun 10;5:109. doi: 10.3389/fphar.2014.00109. eCollection 2014.
Impact factor:
Publication type: Letter or abstract
Authors: Alvarez-Madrazo, Samantha; Baumgartel, Christoph; Brzezinska, Anna; Bucsics, Anna; Campbell, Stephen; Cars, Thomas; Diogene, Eduardo; Eriksson, Irene; Finlayson, Alexander; Furst, Jurij et al.
DOI: 10.3389/fphar.2014.00109

Association of musculoskeletal complaints and gliptin use: review of spontaneous reports.

PMID: 23960039
Journal: PHARMACOEPIDEMIOLOGY AND DRUG SAFETY
Year: 2013
Reference: Pharmacoepidemiol Drug Saf. 2013 Oct;22(10):1115-8. doi: 10.1002/pds.3503. Epub 2013 Aug 19.
Impact factor:
Publication type: Paper in international publication
Authors: Cereza, Gloria; Figueras, Albert; Tarapues, Monica et al.
DOI: 10.1002/pds.3503

New statins also produce fatigue: spontaneous reporting as a complementary system to increase safety knowledge.

PMID: 23400662
Journal: JAMA internal medicine
Year: 2013
Reference: JAMA Intern Med. 2013 Feb 11;173(3):247-8. doi: 10.1001/jamainternmed.2013.1614.
Impact factor:
Publication type: Letter or abstract
Authors: Cereza, Gloria; Figueras, Albert; Tarapues, Monica et al.
DOI: 10.1001/jamainternmed.2013.1614

High prevalence of confirmed, but also of potential and believed, neuropathic pain in pain clinics.

PMID: 22927200
Journal: EUROPEAN JOURNAL OF PAIN
Year: 2013
Reference: Eur J Pain. 2013 Mar;17(3):347-56. doi: 10.1002/j.1532-2149.2012.00204.x. Epub 2012 Aug 24.
Impact factor:
Publication type: Paper in international publication
Authors: Barutell, C; Failde, I; Galvez, R; Mico, J A; Perez, C; Ribera, M V; Sanchez-Magro, I; Stern, A et al.
DOI: 10.1002/j.1532-2149.2012.00204.x

Available evidence and outcome of off-label use of rituximab in clinical practice.

PMID: 23700188
Journal: EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY
Year: 2013
Reference: Eur J Clin Pharmacol. 2013 Sep;69(9):1689-99. doi: 10.1007/s00228-013-1518-4. Epub 2013 May 23.
Impact factor:
Publication type: Paper in international publication
Authors: Agusti, A; Alerany, C; Bosch, J A; Cortes-Hernandez, J; Danes, I; Ferrer, A; Lopez, A; Martinez, J; Vallano, A et al.
DOI: 10.1007/s00228-013-1518-4

Nightmares induced by montelukast in children and adults.

PMID: 23204025
Journal: EUROPEAN RESPIRATORY JOURNAL
Year: 2012
Reference: Eur Respir J. 2012 Dec;40(6):1574-5. doi: 10.1183/09031936.00092812.
Impact factor:
Publication type: Letter whit IF
Authors: Cereza, Gloria; Garcia Dolade, Nuria; Laporte, Joan-Ramon et al.
DOI: 10.1183/09031936.00092812

Pregnancy after treatment of breast cancer in young women does not adversely affect the prognosis.

PMID: 22018510
Journal: BREAST
Year: 2012
Reference: Breast. 2012 Jun;21(3):272-5. doi: 10.1016/j.breast.2011.10.001. Epub 2011 Oct 21.
Impact factor:
Publication type: Paper in international publication
Authors: ; ; ; ; ; ; et al.
DOI: 10.1016/j.breast.2011.10.001

[Disease modifying drugs in multiple sclerosis and pregnancy.]

PMID: 22743277
Journal: MEDICINA CLINICA
Year: 2012
Reference: Med Clin (Barc). 2012 Sep 22;139(7):316-8. doi: 10.1016/j.medcli.2012.04.021. Epub 2012 Jun 27.
Impact factor:
Publication type: Editorial in national publication
Authors: ; ; et al.
DOI: 10.1016/j.medcli.2012.04.021

[The crisis and medicines policy.]

PMID: 22578399
Journal: Atencion Primaria
Year: 2012
Reference: Aten Primaria. 2012 Jun;44(6):306-8. doi: 10.1016/j.aprim.2012.03.006. Epub 2012 May 10.
Impact factor:
Publication type: Editorial in national publication
Authors: ; et al.
DOI: 10.1016/j.aprim.2012.03.006

Lipid-lowering drugs in ischaemic heart disease: A quasi-experimental uncontrolled before-and-after study of the effectiveness of clinical practice guidelines.

PMID: 21816068
Journal: BMC Cardiovascular Disorders
Year: 2011
Reference: BMC Cardiovasc Disord. 2011 Aug 4;11:47.
Impact factor:
Publication type: Paper in international publication
Authors: ; ; ; ; ; ; ; ; et al.
DOI: 10.1186/1471-2261-11-47

Republished editorial: What public policies have been more effective in promoting rational prescription of drugs?

PMID: 21788233
Journal: POSTGRADUATE MEDICAL JOURNAL
Year: 2011
Reference: Postgrad Med J. 2011 Aug;87(1030):507-8.
Impact factor:
Publication type: Editorail in international publication
Authors: Diogene, Eduard; Figueras, Albert et al.
DOI: 10.1136/pgmj.2009.101311rep

Paracetamol in therapeutic dosages and acute liver injury: causality assessment in a prospective case series.

PMID: 21762481
Journal: BMC GASTROENTEROLOGY
Year: 2011
Reference: BMC Gastroenterol. 2011 Jul 15;11:80.
Impact factor:
Publication type: Paper in international publication
Authors: ; ; ; ; ; ; ; ; ; et al.
DOI: 10.1186/1471-230X-11-80

Synergism between Prior Anisakis simplex Infections and Intake of NSAIDs, on the Risk of Upper Digestive Bleeding: A Case-Control Study.

PMID: 21738810
Journal: PLoS Neglected Tropical Diseases
Year: 2011
Reference: PLoS Negl Trop Dis. 2011 Jun;5(6):e1214. Epub 2011 Jun 28.
Impact factor:
Publication type: Paper in international publication
Authors: Aguirre, Carmelo; Anadon, Ana M; Carvajal, Alfonso; Figueiras, Adolfo; Ibanez, Luisa; Lopez-Goikoetxea, Maria Jose; Ortega, Sara; Salgado, Angel; Ubeira, Florencio M et al.
DOI: 10.1371/journal.pntd.0001214

Effect of an intervention on the features of adverse drug reactions spontaneously reported in a hospital.

PMID: 20552176
Journal: EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY
Year: 2010
Reference: Eur J Clin Pharmacol. 2010 Sep;66(9):937-45. Epub 2010 Jun 16.
Impact factor:
Publication type: Paper in international publication
Authors: ; ; ; ; ; ; ; et al.
DOI: 10.1007/s00228-010-0856-8

Consent in clinical trials: What do patients know?

PMID: 20462521
Journal: Contemporary Clinical Trials
Year: 2010
Reference: Contemp Clin Trials. 2010 Sep;31(5):443-6. Epub 2010 May 10.
Impact factor:
Publication type: Paper in international publication
Authors: ; ; ; ; ; et al.
DOI: 10.1016/j.cct.2010.05.004

Use of non-specific intravenous human immunoglobulins in Spanish hospitals; need for a hospital protocol.

PMID: 20204337
Journal: EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY
Year: 2010
Reference: Eur J Clin Pharmacol. 2010 Jun;66(6):633-41. Epub 2010 Mar 5.
Impact factor:
Publication type: Paper in international publication
Authors: ; ; ; ; ; ; ; ; ; et al.
DOI: 10.1007/s00228-010-0800-y

Efficacy of psychostimulant drugs for cocaine dependence.

PMID: 20166094
Journal: Cochrane Database of Systematic Reviews
Year: 2010
Reference: Cochrane Database Syst Rev. 2010 Feb 17;2:CD007380.
Impact factor:
Publication type: Review in international publication
Authors: Capella, Dolors; Casas, Miguel; Castells, Xavier; Perez-Mana, Clara; Roncero, Carlos; Vidal, Xavier et al.
DOI: 10.1002/14651858.CD007380.pub3

[The need to select drugs: the responsibility of choosing]

PMID: 19828213
Journal: Atencion Primaria
Year: 2009
Reference: Aten Primaria. 2009 Dec;41(12):657-8.
Impact factor:
Publication type: Letter or abstract
Authors: Abaurrea, Pilar; Agreda, Javier; Alonso, Rosario; Asensio Ostos, Carmen; Botija, Pilar; Castro, Jose Antonio; Corredera, Angel; Daza, Pablo; de la Figuera, Enrique; Diogene Fadini, Eduard et al.
DOI: 10.1016/j.aprim.2009.09.003

Efficacy of opiate maintenance therapy and adjunctive interventions for opioid dependence with comorbid cocaine use disorders: a systematic review and meta-analysis of controlled clinical trials.

PMID: 20180662
Journal: Am J Drug Alcohol Abuse
Year: 2009
Reference: Am J Drug Alcohol Abuse. 2009;35(5):339-49.
Impact factor:
Publication type: Letter or abstract
Authors: Capella, Dolors; Casas, Miguel; Castells, Xavier; Colom, Joan; Kosten, Thomas R; Vidal, Xavier et al.
DOI: 10.1080/00952990903108215

Randomized clinical trial of the effectiveness of a home-based intervention in patients with heart failure: the IC-DOM study.

PMID: 19401125
Journal: REVISTA ESPANOLA DE CARDIOLOGIA
Year: 2009
Reference: Rev Esp Cardiol. 2009 Apr;62(4):400-8.
Impact factor:
Publication type: Paper in national publication
Authors: Alegre, Jose; Ballarin, Elena; Brotons, Carlos; Casanovas, Jordi; Cata, Teresa; Falces, Carles; Martinez, Mireia; Moral, Irene; Ortiz, Jacint; Perez, Eulalia et al.
DOI:

Prevalence of CYP2C9 polymorphisms in the south of Europe.

PMID: 19381164
Journal: PHARMACOGENOMICS JOURNAL
Year: 2009
Reference: Pharmacogenomics J. 2009 Oct;9(5):306-10.
Impact factor:
Publication type: Paper in international publication
Authors: Aguirre, Carmelo; Blanco, Adoracion; Carracedo, Angel; Estany-Gestal, Ana; Figueiras, Adolfo; Ibanez, Luisa; Passiu, Marianna; Provezza, Lisa; Ramos-Ruiz, Ricardo; Ruiz, Borja et al.
DOI: 10.1038/tpj.2009.16

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