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Clinical Pharmacology

The aim of our group is to investigate the use of medicines and evaluate its benefit/risk relationship in usual clinical practice. Our group coordinates the Catalan centre of the Spanish System of Pharmacovigilance. Research activities on pharmacology and pharmacoepidemiology are coupled with undergraduate teaching at the Autonomous University of Barcelona Medical School, training of specialists in clinical pharmacology, and continuous education of health professionals on therapeutics.

The group is a Special Group of Research recognized by AGAUR GenCat.  It is a partner of “The European Consortium “EU PE&PV Network” (European Pharmacoepidemiology and Pharmacovigilance Network)” and it is part of the European Network of Centres for Pharmacoepidemiology and Pharmacovigilance (ENCePP). It gives institutional support to the Clinical Research Ethical Committee of the University hospital Vall d’Hebron (UHVH), the Drug and Pharmacotherapeutic Committee of the UHVH, and also to the Drug and Pharmacotherapeutic Committee of the Institut Català de la Salut. 

Team

Lina Fernanda Camacho Arteaga

Lina Fernanda Camacho Arteaga

Research technician
Clinical Pharmacology
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Montse Bosch Ferrer

Montse Bosch Ferrer

Clinical Pharmacology
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Bellas Fernandez, Lucia

Bellas Fernandez, Lucia

Predoctoral researcher
Clinical Pharmacology
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Camacho Arteaga, Lina Fernanda

Camacho Arteaga, Lina Fernanda

Research technician
Clinical Pharmacology
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Mata  Ley, Suyvan Esther

Mata Ley, Suyvan Esther

Predoctoral researcher
Clinical Pharmacology
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Alba Vimes Fortis

Alba Vimes Fortis

Research assistant
Clinical Pharmacology
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Lina Fernanda Camacho Arteaga

Lina Fernanda Camacho Arteaga

Research technician
Clinical Pharmacology
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Montse Bosch Ferrer

Montse Bosch Ferrer

Clinical Pharmacology
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Bellas Fernandez, Lucia

Bellas Fernandez, Lucia

Predoctoral researcher
Clinical Pharmacology
Read more
Camacho Arteaga, Lina Fernanda

Camacho Arteaga, Lina Fernanda

Research technician
Clinical Pharmacology
Read more
Mata  Ley, Suyvan Esther

Mata Ley, Suyvan Esther

Predoctoral researcher
Clinical Pharmacology
Read more
Alba Vimes Fortis

Alba Vimes Fortis

Research assistant
Clinical Pharmacology
Read more

Research lines

PROTECT (Pharmacoepidemiological Research on Outcome of Therapeutics by a European ConsorTium

The goal of this project is to strengthen the monitoring of benefit-risk of medicines in Europe by developing innovative methods that will enhance the early detection and assessment of adverse drug reaction from different data sources (clinical trials, spontaneous reporting and observational studies). Our group is responsible for working on the use of national drug utilisation data. The specific tasks are to build and update an inventory of data sources on the consumption of the medicines of interest, to evaluate and disseminate methodologies for drug utilisation studies in order to estimate the potential public health impact of adverse drug reactions.

IP: Joan-Ramon Laporte Roselló, Luisa Ibáñez Mora

Risk of blood dyscrasias associated with the use of medicines

IP: -

Study of drug-induced liver disease

IP: -

Projects

Detección de falsos positivos en pacientes con alertas electrónicas de alergia a betalactámicos en las historias clínicas

IP: Victòria Cardona Dahl
Collaborators: Maria Antònia Agustí Escasany, Laura Gomez Ganda
Funding agency: Instituto de Salud Carlos III
Funding: 30250
Reference: PI19/01656
Duration: 01/01/2020 - 30/06/2024

Publications

Validation of the Spanish version of DYsphagia in MUltiple Sclerosis questionnaire (DYMUS).

PMID: 37086636
Journal: Multiple Sclerosis and Related Disorders
Year: 2023
Reference: Mult Scler Relat Disord. 2023 Apr 17;74:104724. doi: 10.1016/j.msard.2023.104724.
Impact factor:
Publication type: Paper in international publication
Authors: Aldevert, Mireia; Anglada, Elisenda; Arevalo, Maria Jesus; Bascunana, Helena; Curto, Gemma; Feliu, Patricia; Galan, Ingrid; Garcia, Itziar; Garcia, Montserrat; Gonzalo, Lorena et al.
DOI: 10.1016/j.msard.2023.104724

Tractional Retinal Detachment Related to Hemoglobin C Trait Retinopathy: A Case Report.

PMID: 37870045
Journal:
Year: 2023
Reference: Turk J Ophthalmol. 2023 Oct 19;53(5):318-321. doi: 10.4274/tjo.galenos.2023.48672.
Impact factor:
Publication type: Paper in international publication
Authors: Agusti, Antonia; Bertolani, Yann; Buck, Paul; Cereza, Gloria; de Abajo, Francisco J; Garcia, Sandra Banderas; Garcia-Arumi, Claudia; Garcia-Arumi, Jose; Garrell-Salat, Xavier; Macia, Miguel A et al.
DOI: 10.4274/tjo.galenos.2023.48672

Common and specific proteins and pathways in heart and cerebral ischemia.

PMID: 37944280
Journal: Journal of Stroke & Cerebrovascular Diseases
Year: 2023
Reference: J Stroke Cerebrovasc Dis. 2023 Nov 7;33(1):107467. doi: 10.1016/j.jstrokecerebrovasdis.2023.107467.
Impact factor:
Publication type: Paper in international publication
Authors: Agudelo, Victor Hugo; Alonso, Javier Robles; Alvarez, Maria Eugenia Vazquez; Amat-Santos, Ignacio J; Andraka, Leire; Anton, Salvador Alvarez; Aquino, Rosa Sanchez; Arellano, Manuel Vizcaino; Arroyo, Jose Ramon Ruiz; Arzamendi, Dabit et al.
DOI: 10.1016/j.jstrokecerebrovasdis.2023.107467

EHS guidelines for inguinal hernia repair. The reality of the current situation in Spain. A proposal to standardize its implementation during surgical training.

PMID: 37951469
Journal: Cirugia espanola
Year: 2023
Reference: Cir Esp (Engl Ed). 2023 Nov 9:S2173-5077(23)00192-8. doi: 10.1016/j.cireng.2023.01.008.
Impact factor:
Publication type: Paper in international publication
Authors: Alfonso, Fernando; Casanova-Sandoval, Juan; Fernandez-Portales, Javier; Garcia Del Blanco, Bruno; Garcia-Touchard, Arturo; Gonzalo, Nieves; Hernandez-Garcia, Jose Maria; Jimenez-Mazuecos, Jesus; Lopez Cano, Manuel; Lopez-Pais, Javier et al.
DOI: 10.1016/j.cireng.2023.01.008

Regulatory and clinical development to support the approval of advanced therapies medicinal products in Japan.

PMID: 35762253
Journal: EXPERT OPINION ON BIOLOGICAL THERAPY
Year: 2022
Reference: Expert Opin Biol Ther. 2022 Jul;22(7):831-842. doi: 10.1080/14712598.2022.2093637. Epub 2022 Jul 4.
Impact factor: 4.388
Publication type: Paper in international publication
Authors: Antonio, Vallano; Merce, Obach; Antonia, Agusti; Carolina, Iglesias-Lopez et al.
DOI: 10.1080/14712598.2022.2093637

Immunogenic dynamics and SARS-CoV-2 variant neutralisation of the heterologous ChAdOx1-S/BNT162b2 vaccination: Secondary analysis of the randomised CombiVacS study.

PMID: 35795713
Journal: EClinicalMedicine
Year: 2022
Reference: EClinicalMedicine. 2022 Jul 1;50:101529. doi: 10.1016/j.eclinm.2022.101529. eCollection 2022 Aug.
Impact factor: 0
Publication type: Paper in international publication
Authors: Castano, Luis; Borobia, Alberto M; Castillo de la Osa, Maria; Gonzalez-Perez, Maria; Garcia-Perez, Javier; Bertran, Maria Jesus; Campins, Magdalena; Lora, David; Perez-Olmeda, Mayte; Alcami, Jose et al.
DOI: 10.1016/j.eclinm.2022.101529

Impact of home CPAP treated obstructive sleep apnea on COVID-19 outcomes in hospitalized patients.

PMID: 35404224
Journal: Journal of Clinical Sleep Medicine
Year: 2022
Reference: J Clin Sleep Med. 2022 Jul 1;18(7):1857-1864. doi: 10.5664/jcsm.10016.
Impact factor: 4.062
Publication type: Paper in international publication
Authors: Sampol, Julia, Saez, Maria, Marti, Sergi, Pallero, Mercedes, Barrecheguren, Miriam, Ferrer, Jaume, Sampol, Gabriel, Vimes Fortis, Alba, Guillen Del Castillo, Alfredo, et al.
DOI: 10.5664/jcsm.10016

Incidence and risk factors for early readmission after hospitalization for SARS-CoV-2 infection: results from a retrospective cohort study.

PMID: 34331263
Journal: INFECTION
Year: 2022
Reference: Infection. 2022 Apr;50(2):371-380. doi: 10.1007/s15010-021-01662-1. Epub 2021 Jul 30.
Impact factor: 3.553
Publication type: Paper in international publication
Authors: Kirkegaard, Cristina, Falco-Roget, Anna, Sanchez-Montalva, Adrian, Valls, Angel, Clofent, David, Campos-Varela, Isabel, Garcia-Garcia, Sonia, Leguizamo, Lina Maria, Sellares-Nadal, Julia, Eremiev, Simeon et al.
DOI: 10.1007/s15010-021-01662-1

The role of liver steatosis as measured with transient elastography and transaminases on hard clinical outcomes in patients with COVID-19.

PMID: 34104210
Journal: Therapeutic Advances in Gastroenterology
Year: 2021
Reference: Therap Adv Gastroenterol. 2021 May 30;14:17562848211016567. doi: 10.1177/17562848211016567. eCollection 2021.
Impact factor: 4.409
Publication type: Paper in international publication
Authors: Campos-Varela, Isabel, Villagrasa, Ares, Simon-Talero, Macarena, Riveiro-Barciela, Mar, Ventura-Cots, Meritxell, Aguilera-Castro, Lara, Alvarez-Lopez, Patricia, Nordahl, Emilie A, Rivera-Esteban, Jesus M, Romero, Alba et al.
DOI: 10.1177/17562848211016567

Withdrawal of hospital outpatient treatments in severe diseases due to unacceptable toxicity: A retrospective study from the Register of Patients and Treatments.

PMID: 33216993
Journal: BRITISH JOURNAL OF CLINICAL PHARMACOLOGY
Year: 2021
Reference: Br J Clin Pharmacol. 2021 Jun;87(6):2549-2557. doi: 10.1111/bcp.14665. Epub 2020 Dec 3.
Impact factor: 4.34
Publication type: Paper in international publication
Authors: Vendrell, Lourdes, Aller, Marta B, Boixareu, Nuria, Garcia-Dolade, Nuria, Diogene, Eduard, Perez, Eulalia, Danes, Immaculada, Bosch, Montserrat, Aguilera, Cristina, Agusti, Antonia et al.
DOI: 10.1111/bcp.14665

Nonsteroidal anti-inflammatory drug use during pregnancy.

PMID: 33627229
Journal: MEDICINA CLINICA
Year: 2021
Reference: Med Clin (Barc). 2021 Jun 11;156(11):568-572. doi: 10.1016/j.medcli.2021.01.009. Epub 2021 Feb 21.
Impact factor: 1.725
Publication type: Paper in national publication
Authors: Sans-Pola, Carla, Guillen, Elena, Aguilera, Cristina et al.
DOI: 10.1016/j.medcli.2021.01.009

Progressive multifocal leukoencephalopathy in the era of new disease-modifying treatments for multiple sclerosis.

PMID: 33431183
Journal: MEDICINA CLINICA
Year: 2021
Reference: Med Clin (Barc). 2021 May 21;156(10):509-514. doi: 10.1016/j.medcli.2020.10.015. Epub 2021 Jan 9.
Impact factor: 1.725
Publication type: Paper in national publication
Authors: Bosch Ferrer, Montserrat, Rodriguez-Acevedo, Breogan, Riera-Arnau, Judit, Filippi-Arriaga, Francesca et al.
DOI: 10.1016/j.medcli.2020.10.015

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