About the VHIR
Here at the Vall d'Hebron Research Institute (VHIR) we promote biomedical research, innovation and teaching. Over 1,800 people are seeking to understand diseases today so the treatment can be improved tomorrow.
Research
We are working to understand diseases, to find out how they operate and to create better treatments for patients. Get to know about our groups and their lines of research.
People
People are the centre of the Vall d'Hebron Research Institute (VHIR). This is why we are bound by the principles of freedom of research, gender equality and professional attitudes that HRS4R promotes.
Clinical trials
Our work is not just basic or translational; we are leaders in clinical research. Enter and find about the clinical trials we are conducting and why we are a world reference in this field.
Progress
Our aim is to make the research carried out at the Vall d’Hebron Research Institute (VHIR) a driving force for transformation. How? By identifying new channels and solutions for the promotion of people's health and well-being.
Core facilities
We offer specialist support for researchers, internal and external alike, ranging from specific services to preparing complete projects. All this, from a perspective of quality and speed of response.
News
We offer you a gateway for staying up to date on everything going on at the Vall d’Hebron Research Institute (VHIR), from the latest news to future solidarity activities and initiatives that we are organising.
The aim of our group is to investigate the use of medicines and evaluate its benefit/risk relationship in usual clinical practice. Our group coordinates the Catalan centre of the Spanish System of Pharmacovigilance. Research activities on pharmacology and pharmacoepidemiology are coupled with undergraduate teaching at the Autonomous University of Barcelona Medical School, training of specialists in clinical pharmacology, and continuous education of health professionals on therapeutics.
The group is a Special Group of Research recognized by AGAUR GenCat. It is a partner of “The European Consortium “EU PE&PV Network” (European Pharmacoepidemiology and Pharmacovigilance Network)” and it is part of the European Network of Centres for Pharmacoepidemiology and Pharmacovigilance (ENCePP). It gives institutional support to the Clinical Research Ethical Committee of the University hospital Vall d’Hebron (UHVH), the Drug and Pharmacotherapeutic Committee of the UHVH, and also to the Drug and Pharmacotherapeutic Committee of the Institut Català de la Salut.
In this line of research, studies of the use of drugs in real clinical practice are mainly carried out, such as monitoring the use of outpatient hospital drugs and medicines evaluated for their special conditions of use (e.g. off-label and compassionate use).
In addition, research is being carried out into the use of medicines within a European consortium led by Utrecht University EU PE&PV, and at the request of the European Medicines Agency (e.g. use of retinoids in women of childbearing age).
IP: Immaculada Danes Carreras, Mònica Sabaté Gallego
Primarily focused on the analysis of acute and chronic postoperative pain and neuropathic pain.
IP: Francisco Javier Medel Rebollo
Analysis of the spontaneous reported adverse drug reactions at the Hospital, in order to improve knowledge of the safety profile of new commercialized drugs and to be able to estimate the incidence of their adverse drug reactions. Analysis of the drug use in the real world setting in order to improve the prevention of adverse drug reactions.
IP: Maria Antònia Agustí Escasany, Cristina Aguilera Martin
In collaboration with three hospitals of the Metropolitan Area of Barcelona the group performs two studies to identify hospital admissions due to acute renal failure and hospital-acquired acute renal failure related to rennin-angiotensin-aldosterone system and other drugs with in-hospital use. The aim is to estimate the incidence rate and the severity, to describe the clinic characteristics and clinical course, the drugs involved, other associated risk factors, the length of the hospital stay, and the economical impact.
IP: Maria Antònia Agustí Escasany
IP: - Collaborators: - Funding agency: Fundación Mutual Médica Funding: 25000 Reference: FMM/BMM/2022/ANDERSSEN Duration: 25/11/2022 - 25/11/2024
IP: Maria Antònia Agustí Escasany Collaborators: Ángeles Mesas Idáñez, Xavier Vidal Guitart, María Gloria Cereza García, Cristina Aguilera Martin, Maria Elena Ballarin Alins, Judit Riera Arnau, Immaculada Danes Carreras, Carla Sans Pola, Francisco Javier Medel Rebollo, Eulàlia Pérez Esquirol, Eduard Diogène Fadini, Mònica Sabaté Gallego, Montse Bosch Ferrer, Lourdes Vendrell Bosch, Lina Fernanda Camacho Arteaga, Lina Fernanda Camacho Arteaga Funding agency: Agència Gestió Ajuts Universitaris i de Recerca Funding: 0.01 Reference: 2021 SGR 00848 Duration: 01/01/2022 - 30/06/2025
IP: Cristina Aguilera Martin Collaborators: - Funding agency: Generalitat de Catalunya - Departament de Salut Funding: 5520 Reference: SLT021/21/000068 Duration: 01/06/2022 - 31/12/2024
PMID: 37334659 Journal: EuroIntervention Year: 2023 Reference: EuroIntervention. 2023 May 19:EIJ-D-23-00204. doi: 10.4244/EIJ-D-23-00204. Impact factor: Publication type: Paper in international publication Authors: Adlam, David; Adriaenssens, Tom; Banning, Amerjeet S; Berry, Colin; Bogaerts, Kris; Buera, Irene; Erglis, Andrejs; Flather, Marcus; Gershlick, Anthony H; Gracey, Jay et al. DOI: 10.4244/EIJ-D-23-00204
PMID: 37663263 Journal: Frontiers in Pharmacology Year: 2023 Reference: Front Pharmacol. 2023 Aug 17;14:1207976. doi: 10.3389/fphar.2023.1207976. eCollection 2023. Impact factor: Publication type: Paper in international publication Authors: Abtahi, Shahab; Alsina, Ema; Andersen, Morten; Ballarin, Elena; Bartolini, Claudia; Duran, Carlos E; Gamba, Magdalena; Garcia-Poza, Patricia; Garcia-Sempere, Anibal; Gini, Rosa et al. DOI: 10.3389/fphar.2023.1207976
PMID: 37793964 Journal: Cardiovascular revascularization medicine : includ Year: 2023 Reference: Cardiovasc Revasc Med. 2023 Sep 28:S1553-8389(23)00827-8. doi: 10.1016/j.carrev.2023.09.008. Impact factor: Publication type: Paper in international publication Authors: Abdul-Jawad, Omar; Abdul-Jawad, Omar; Andrea, Rut; Angiolillo, Dominick J; Brugaletta, Salvatore; Cardenas, Merida; Carrillo, Xavier; Cepas-Guillen, Pedro Luis; de Diego, Oriol; Freixa, Xavier et al. DOI: 10.1016/j.carrev.2023.09.008
PMID: 37131861 Journal: The Lancet regional health. Europe Year: 2023 Reference: Lancet Reg Health Eur. 2023 May;28:100613. doi: 10.1016/j.lanepe.2023.100613. Epub 2023 Apr 14. Impact factor: Publication type: Paper in international publication Authors: Alvarez-Mon, Melchor; Anagua, Jesse Omar; Arana-Arri, Eunate; Arribas, Jose R; Bailon, Lucia; Barreiro, Antonio; Benet, Susana; Blanch-Lombarte, Oscar; Blanco, Julia; Borobia, Alberto M et al. DOI: 10.1016/j.lanepe.2023.100613
PMID: 35114859 Journal: ANNALS OF MEDICINE Year: 2022 Reference: Ann Med. 2022 Dec;54(1):379-392. doi: 10.1080/07853890.2021.2016940. Impact factor: 4.709 Publication type: Paper in international publication Authors: Figueiras, Adolfo; Salgado, Angel; Mallah, Narmeen; Zapata-Cachafeiro, Maruxa; Aguirre, Carmelo; Ibarra-Garcia, Eguzkine; Palacios-Zabalza, Itziar; Macias-Garcia, Fernando; Pineiro-Lamas, Maria; Ibanez, Luisa et al. DOI: 10.1080/07853890.2021.2016940
PMID: 33846003 Journal: MEDICINA CLINICA Year: 2022 Reference: Med Clin (Barc). 2022 Feb 11;158(3):111-117. doi: 10.1016/j.medcli.2020.12.041. Epub 2021 Apr 9. Impact factor: 1.725 Publication type: Paper in national publication Authors: Crespo-Fresno, Almudena; Vidal-Guitart, Xavier; Sanchez-Raya, Judith; Pages-Bolibar, Esther; Cuxart-Fina, Ampar et al. DOI: 10.1016/j.medcli.2020.12.041
PMID: 35127085 Journal: Molecular and clinical oncology Year: 2022 Reference: Mol Clin Oncol. 2022 Mar;16(3):60. doi: 10.3892/mco.2022.2493. Epub 2022 Jan 12. Impact factor: 0 Publication type: Letter or abstract Authors: Hernando, Jorge; Riera-Arnau, Judit; Roca, Maria; Garcia, Alejandro; Capdevila, Jaume et al. DOI: 10.3892/mco.2022.2493
PMID: 35134393 Journal: JOURNAL OF AFFECTIVE DISORDERS Year: 2022 Reference: J Affect Disord. 2022 Apr 15;303:131-137. doi: 10.1016/j.jad.2022.02.001. Epub 2022 Feb 5. Impact factor: 4.839 Publication type: Paper in international publication Authors: van Dijk, L; Camacho-Arteaga, L F; Gardarsdottir, H; Ibanez, L; Souverein, P C; Ballarin, E; Sabate, M; Vidal, X; Hek, K et al. DOI: 10.1016/j.jad.2022.02.001
PMID: 34830495 Journal: Journal of Clinical Medicine Year: 2021 Reference: J Clin Med. 2021 Nov 9;10(22). pii: jcm10225213. doi: 10.3390/jcm10225213. Impact factor: 4.242 Publication type: Paper in international publication Authors: Sempere, Abiu, Salvador, Fernando, Monforte, Arnau, Sampol, Julia, Espinosa-Pereiro, Juan, Miarons, Marta, Bosch-Nicolau, Pau, Guillen-Del-Castillo, Alfredo, Aznar, Maria Luisa, Campos-Varela, Isabel et al. DOI: 10.3390/jcm10225213
PMID: 34768461 Journal: Journal of Clinical Medicine Year: 2021 Reference: J Clin Med. 2021 Oct 26;10(21). pii: jcm10214941. doi: 10.3390/jcm10214941. Impact factor: 4.242 Publication type: Paper in international publication Authors: Sans-Pola, Carla, Agusti, Antonia, Bosch, Josep Angel, Agraz, Irene, Alerany, Carmen, Danes, Immaculada et al. DOI: 10.3390/jcm10214941
PMID: 34464214 Journal: Journal of Managed Care & Specialty Pharmacy Year: 2021 Reference: J Manag Care Spec Pharm. 2021 Sep;27(9):1210-1220. doi: 10.18553/jmcp.2021.27.9.1210. Impact factor: 2.903 Publication type: Paper in international publication Authors: Charlton, Alethea, Vidal, Xavier, Sabate, Monica, Bailarin, Elena, Martinez, Lina Maria Leguizamo, Ibanez, Luisa et al. DOI: 10.18553/jmcp.2021.27.9.1210
PMID: 34232478 Journal: CLINICAL DRUG INVESTIGATION Year: 2021 Reference: Clin Drug Investig. 2021 Aug;41(8):701-710. doi: 10.1007/s40261-021-01058-x. Epub 2021 Jul 7. Impact factor: 2.859 Publication type: Paper in international publication Authors: Jouanjus, Emilie, Sans-Pola, Carla, Mainoli, Beatrice, Javid, Farideh A, Ekheden, Isabella, Guillen, Elena, Freixo, Cristiana, Alcubilla, Pau, Mazhar, Faizan, Turner, Richard et al. DOI: 10.1007/s40261-021-01058-x
PMID: 31065742 Journal: EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY Year: 2019 Reference: Eur J Clin Pharmacol. 2019 Aug;75(8):1161-1176. doi: 10.1007/s00228-019-02684-3. Epub 2019 May 8. Impact factor: 2.774 Publication type: Paper in international publication Authors: Alonso RamÃrez, Javier, Fernández Oropesa, Carlos, López Varona, Mª José, AcÃn Gerico, Mª Teresa, Sanz Alvarez, Emilio, MartÃn de la Sierra, MarÃa Ãngeles, Peñalver, MarÃa José, Falomir Gómez, Teresa, Ruiz Salazar, Jesús, Rivas, Gabriela Elizondo et al. DOI: 10.1007/s00228-019-02684-3
PMID: 30565019 Journal: DRUG SAFETY Year: 2019 Reference: Drug Saf. 2019 May;42(5):683-687. doi: 10.1007/s40264-018-0768-6. Impact factor: 3.526 Publication type: Paper in international publication Authors: Sultana, Janet, Moretti, Ugo, Addis, Antonio, Caduff, Pia, Capuano, Annalisa, Kant, Agnes, Laporte, Joan-Ramon, Lindquist, Marie, Raine, June, Sartori, Daniele et al. DOI: 10.1007/s40264-018-0768-6
PMID: 29956217 Journal: DRUG SAFETY Year: 2018 Reference: Drug Saf. 2018 Dec;41(12):1325-1331. doi: 10.1007/s40264-018-0695-6. Impact factor: 3.585 Publication type: Paper in international publication Authors: Ortiz de Landaluce, Leticia, Carbonell, Pere, Asensio, Carmen, Escoda, Nuria, Laporte, Joan-Ramon, Lopez, Pilar et al. DOI: 10.1007/s40264-018-0695-6
PMID: 29887173 Journal: MEDICINA CLINICA Year: 2018 Reference: Med Clin (Barc). 2018 Dec 21;151(12):498-502. doi: 10.1016/j.medcli.2018.05.008. Epub 2018 Jun 7. Impact factor: 1.168 Publication type: Paper in national publication Authors: Peremiquel-Trillas, Paula, Leguizamo, Lina Maria, Asensio Ostos, Carmen, Martinez-Gomez, Xavier et al. DOI: 10.1016/j.medcli.2018.05.008
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PMID: 31156839 Journal: European Journal of Hospital Pharmacy-Science and Practice Year: 2016 Reference: Eur J Hosp Pharm. 2016 May;23(3):161-165. doi: 10.1136/ejhpharm-2015-000770. Epub 2015 Oct 28. Impact factor: 0.432 Publication type: Paper in international publication Authors: Salat, D, Llop, R, Aguilera, C, Danes, I, Bosch, M, Asensio, C, Castaneda, F, Esterlich, E, Vallano, A et al. DOI: 10.1136/ejhpharm-2015-000770
PMID: 26707367 Journal: BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY Year: 2016 Reference: Basic Clin Pharmacol Toxicol. 2016 Jul;119(1):3-9. doi: 10.1111/bcpt.12550. Epub 2016 Feb 3. Impact factor: 3.097 Publication type: Paper in international publication Authors: Ferrer, Pili, Amelio, Justyna, Ballarin, Elena, Sabate, Monica, Rottenkolber, Marietta, Schmiedl, Sven, Laporte, Joan-Ramon, Ibanez, Luisa, Vidal, Xavi et al. DOI: 10.1111/bcpt.12550
PMID: 26799344 Journal: PHARMACOEPIDEMIOLOGY AND DRUG SAFETY Year: 2016 Reference: Pharmacoepidemiol Drug Saf. 2016 Jun;25(6):725-32. doi: 10.1002/pds.3967. Epub 2016 Jan 22. Impact factor: 2.908 Publication type: Paper in international publication Authors: Laporte, Joan-Ramon et al. DOI: 10.1002/pds.3967
PMID: 27151175 Journal: BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY Year: 2016 Reference: Basic Clin Pharmacol Toxicol. 2016 Nov;119(5):476-484. doi: 10.1111/bcpt.12615. Epub 2016 May 25. Impact factor: 3.097 Publication type: Paper in international publication Authors: Villar, Maria M, Iavecchia, Lujan, Safiya, Ahmad, Salat, David, Sabate, Monica, Bosch, Montse, Biarnes, Alfons, Camps, Angels, Castella, Dolors, Lalueza, Pilar et al. DOI: 10.1111/bcpt.12615
PMID: 26543747 Journal: SpringerPlus Year: 2015 Reference: Springerplus. 2015 Oct 15;4:612. doi: 10.1186/s40064-015-1398-4. eCollection 2015. Impact factor: 0 Publication type: Paper in international publication Authors: Rottenkolber, Marietta, Ferrer, Pili, Sabate, Monica, Ballarin, Elena, Fortuny, Joan, Ibanez, Luisa, Laporte, Joan-Ramon, Schmiedl, Sven et al. DOI: 10.1186/s40064-015-1398-4
PMID: 24625054 Journal: BMC research notes Year: 2014 Reference: BMC Res Notes. 2014 Mar 13;7:143. doi: 10.1186/1756-0500-7-143. Impact factor: Publication type: Letter or abstract Authors: Reynolds, R F, Sabate, Monica, Pacheco, Juan Fernando, Ballarin, Elena, Ferrer, Pili, Petri, Hans, Hasford, Joerg, Schoonen, Marieke Wilma, Rottenkolber, Marietta, Fortuny, Joan et al. DOI: 10.1186/1756-0500-7-143
PMID: 24875352 Journal: INT J PUBLIC HEALTH Year: 2014 Reference: Int J Public Health. 2014 Oct;59(5):877-87. doi: 10.1007/s00038-014-0564-8. Epub 2014 May 30. Impact factor: 1.966 Publication type: Paper in international publication Authors: Ferrer, Pili, Ballarin, Elena, Sabate, Monica, Laporte, Joan-Ramon, Schoonen, Marieke, Rottenkolber, Marietta, Fortuny, Joan, Hasford, Joerg, Tatt, Iain, Ibanez, Luisa et al. DOI: 10.1007/s00038-014-0564-8
PMID: 23276615 Journal: MEDICINA CLINICA Year: 2013 Reference: Med Clin (Barc). 2013 Mar 2;140(5):229-31. doi: 10.1016/j.medcli.2012.10.015. Epub 2012 Dec 29. Impact factor: 1.399 Publication type: Paper in national publication Authors: Bosch, Montserrat, Llop, Roser, Lalueza, Pilar, Villar, Maria del Mar et al. DOI: 10.1016/j.medcli.2012.10.015
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PhD student: Carolina Iglesias Lòpez Director/s: Maria Antònia Agustí Escasany, Antoni Vallano Ferraz University: Universitat Autònoma de Barcelona Year: 2023
PhD student: Lina Fernanda Camacho Arteaga, Lina Fernanda Camacho Arteaga Director/s: Mònica Sabaté Gallego, Xavier Vidal Guitart University: Universidad Autònoma de Barcelona Year: 2022
The creation of hybrid digital-human interaction spaces between avatars and people offers new opportunities for personalized medicine
The study by physician Emilie Anderssen seeks to optimize the medicalization of people living in nursing homes.
