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Nephrology and kidney transplantation

Our research group is accredited by the Agency for Management of University and Research Grants (AGAUR) in Catalonia, and focuses on two main areas of interest which are related to Solid Organ Transplantation and especially Kidney, and in clinical Nephrology. We tackle these areas from an innovative perspective, both basic-experimental and mechanistic, always with a translational goal. On the one hand, we investigate, develop, and use novel diagnostic and therapeutic technologies to decipher and target main molecular and immune mechanisms of transplant rejection as well as the immune susceptibility to opportunistic infections and malignancies. Also, a main task force of the group is devoted to better understand the main mechanisms involved in certain autoimmune glomerular diseases and idiopathic nephrotic syndrome as well as in diabetic kidney disease, having a specific interest in the role of the renin-angiotensin system. Our ultimate goal is to improve the management and care of patients suffering from kidney diseases as well as their quality of life, reducing associated morbidity and mortality.

Team

Irene Agraz Pamplona

Irene Agraz Pamplona

Senior researcher
Nephrology and kidney transplantation
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Joana Sellarés Roig

Joana Sellarés Roig

Main researcher
Nephrology and kidney transplantation
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M Antonieta Azancot Rivero

M Antonieta Azancot Rivero

Postdoctoral researcher
Nephrology and kidney transplantation
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Manel  Perelló Carrascosa

Manel Perelló Carrascosa

Senior researcher
Nephrology and kidney transplantation
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Nestor Gabriel Toapanta Gaibor

Nestor Gabriel Toapanta Gaibor

Predoctoral researcher
Nephrology and kidney transplantation
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Irene Sanchez Marquez

Irene Sanchez Marquez

Research technician
Nephrology and kidney transplantation
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Irene Agraz Pamplona

Irene Agraz Pamplona

Senior researcher
Nephrology and kidney transplantation
Read more
Joana Sellarés Roig

Joana Sellarés Roig

Main researcher
Nephrology and kidney transplantation
Read more
M Antonieta Azancot Rivero

M Antonieta Azancot Rivero

Postdoctoral researcher
Nephrology and kidney transplantation
Read more
Manel  Perelló Carrascosa

Manel Perelló Carrascosa

Senior researcher
Nephrology and kidney transplantation
Read more
Nestor Gabriel Toapanta Gaibor

Nestor Gabriel Toapanta Gaibor

Predoctoral researcher
Nephrology and kidney transplantation
Read more
Irene Sanchez Marquez

Irene Sanchez Marquez

Research technician
Nephrology and kidney transplantation
Read more

Projects

Creación de un método de referencia para detectar Apo-lb por espectrometría de masas dirigida y validación clínica de su potencial como biomarcadore para el síndrome nefrótico idiopático

IP: Concepció Jacobs Cachá
Collaborators: Laura Conesa Milian, Yolanda Villena Ortiz, Joan López Hellin, Mireia Salvadó Pau, Carmen Llorens Cebriá, Juan Carlos León Román
Funding agency: Instituto de Salud Carlos III
Funding: 71250
Reference: PI24/01573
Duration: 01/01/2025 - 31/12/2027

ROL DE LA APELINA EN LA ENFERMEDAD RENAL DIABÉTICA: DEL RATÓN AL HUMANO

IP: Maria Jose Soler Romeo
Collaborators: Sara Nuñez Delgado, Marina Lopez Martinez, Jordi Vilardell Vila, Irene Martinez Diaz, Sheila Bermejo Garcia, Vicent Muñoz Vaño, Carmen Llorens Cebriá, M Antonieta Azancot Rivero, Enzamaría Fidilio Meli, Juan Carlos León Román
Funding agency: Instituto de Salud Carlos III
Funding: 190000
Reference: PI24/01510
Duration: 01/01/2025 - 31/12/2027

RESETTING THE IMMUNOLOGICAL SYSTEM OF HYPERSENSITIZED TRANSPLANT CANDIDATES TO ALLOW ACCESS TO HLA COMPATIBLE KIDNEY TRANSPLANTATION (RESET TRIAL)

IP: Oriol Bestard Matamoros
Collaborators: Ana Pérez González, RESETTING THE IMMUNOLOGICAL SYSTEM OF HYPERSENSITIZED TRANSPLANT CANDIDATES TO ALLOW ACCESS TO HLA COMPATIBLE KIDNEY TRANSPLANT, Elena Isabel Crespo Gimeno, Laura Donadeu Casassas, RESETTING THE IMMUNOLOGICAL SYSTEM OF HYPERSENSITIZED TRANSPLANT CANDIDATES TO ALLOW ACCESS TO HLA COMPATIBLE KIDNEY TRANSPLANT, Maria Antonia Emilia Meneghini, Delphine Kervella, Cristina Font Miñarro
Funding agency: Instituto de Salud Carlos III
Funding: 465456.69
Reference: ICI24/00066
Duration: 01/01/2025 - 31/12/2029

Nova proteïna de fusió bi-específica de segona generació per prevenir el rebuig dels trasplantaments

IP: Oriol Bestard Matamoros
Collaborators: Anna Martinez Lacalle, Delphine Kervella
Funding agency: Generalitat de Catalunya - Departament de Salut
Funding: 165165
Reference: SLT036/24/000043
Duration: 21/12/2024 - 20/12/2026

Blog

News

Antibody-mediated rejection remains one of the leading causes of graft loss following kidney transplantation. A VHIR study investigating a novel therapeutic strategy to address this challenge has been recognized with the Young Investigator Award 2026.

The distinction from the Catalan Transplant Society will allow her to become a member of the Royal Academy of Medicine of Catalonia.

The Department of Health of the Generalitat de Catalunya grants subsidies for carrying out validation tests on innovative projects in the field of health that are in the early stages of development.