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Research Group on Status Epilepticus and Acute Seizures

The Research Group on Status Epilepticus and Acute Seizures is a young and emerging team, consolidated in national and international clinical research and in the comprehensive and multidisciplinary approach to epilepsy. The scientific challenge of the group is based on understanding, improving and strengthening knowledge about the different fields of epilepsy and how to help solve problems related to epileptic seizures and their consequences.

Among the different projects of the group, it is worth mentioning the search for new biomarkers related to the mechanisms of epileptogenesis, obtaining tools and biomarkers to help diagnose status epilepticus and predict its prognosis, the acquisition of neuroimaging parameters and their relationship with the cognitive status of patients, and other studies to accelerate the diagnostic processes and optimize the therapeutic management of patients with drug-resistant epilepsy. 

Team

Elena Fonseca Hernandez

Elena Fonseca Hernandez

Main researcher
Research Group on Status Epilepticus and Acute Seizures
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Manuel Quintana Luque

Manuel Quintana Luque

Research technician
Research Group on Status Epilepticus and Acute Seizures
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Manuel Toledo Argany

Manuel Toledo Argany

Research Group on Status Epilepticus and Acute Seizures
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Enric Bellido Castillo

Enric Bellido Castillo

Research technician
Research Group on Status Epilepticus and Acute Seizures
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LAURA ABRAIRA DEL FRESNO

LAURA ABRAIRA DEL FRESNO

Main researcher
Research Group on Status Epilepticus and Acute Seizures
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Lallana  Serrano, Sofia

Lallana Serrano, Sofia

Predoctoral researcher
Research Group on Status Epilepticus and Acute Seizures
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Elena Fonseca Hernandez

Elena Fonseca Hernandez

Main researcher
Research Group on Status Epilepticus and Acute Seizures
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Manuel Quintana Luque

Manuel Quintana Luque

Research technician
Research Group on Status Epilepticus and Acute Seizures
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Manuel Toledo Argany

Manuel Toledo Argany

Research Group on Status Epilepticus and Acute Seizures
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Enric Bellido Castillo

Enric Bellido Castillo

Research technician
Research Group on Status Epilepticus and Acute Seizures
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LAURA ABRAIRA DEL FRESNO

LAURA ABRAIRA DEL FRESNO

Main researcher
Research Group on Status Epilepticus and Acute Seizures
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Lallana  Serrano, Sofia

Lallana Serrano, Sofia

Predoctoral researcher
Research Group on Status Epilepticus and Acute Seizures
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Projects

Evaluación multimodal mediante biomarcadores para la predicción y manejo personalizado de la epilepsia secundaria a subaracnoidea aneurismática

IP: Santamarina Pérez, Estevo
Collaborators: Perez Lasarte, Laia, Campos Fernández, Daniel
Funding agency: Fundació Institut de Recerca HUVH
Funding: 117000
Reference: GDORADO/DANIEL_CF
Duration: 08/06/2023 - 07/06/2025

ESTUDIO DE BIOMARCADORES RELACIONADOS CON EPILEPSIA EN LA HEMORRAGIA SUBARACNOIDEA

IP: ABRAIRA DEL FRESNO, LAURA
Collaborators: Penalba Morenilla, Anna, Toledo Argany, Manuel, Sánchez Corral, Anna, Fonseca Hernandez, Elena, Campos Fernández, Daniel, Santamarina Pérez, Estevo, Quintana Luque, Manuel
Funding agency: Fundación Eugenio Rodríguez Pascual
Funding: 24990
Reference: FERP-2022-FERP-2022-1
Duration: 01/01/2023 - 31/12/2024

Grup de Recerca de l'estat epilèptic i crisis agudes

IP: Santamarina Pérez, Estevo
Collaborators: Sánchez López, Javier, Toledo Argany, Manuel, ABRAIRA DEL FRESNO, LAURA, Fonseca Hernandez, Elena, Bellido Castillo, Enric, Campos Fernández, Daniel, Quintana Luque, Manuel
Funding agency: AGAUR no fer servir-correcte 4301-37
Funding: 0.01
Reference: 2021 SGR 00047
Duration: 01/01/2022 - 31/12/2024

USO DE MARCADORES EN LA DETECCIÓN DE CRISIS EPILÉPTICAS DE MAL PRONÓSTICO

IP: Santamarina Pérez, Estevo
Collaborators: Sueiras Gil, Maria, Fonseca Hernandez, Elena, Quintana Luque, Manuel, Restrepo Vera, Juan Luis
Funding agency: Instituto de Salud Carlos III
Funding: 73810
Reference: PI19/01575
Duration: 01/01/2020 - 30/06/2024

Publications

Association of Mortality and Risk of Epilepsy With Type of Acute Symptomatic Seizure After Ischemic Stroke and an Updated Prognostic Model.

PMID: 37036702
Journal: JAMA Neurology
Year: 2023
Reference: JAMA Neurol. 2023 Apr 10. doi: 10.1001/jamaneurol.2023.0611.
Impact factor:
Publication type: Paper in international publication
Authors: Abraira, Laura; Alvarez-Sabin, Jose; Baumann, Christian R; Bayona-Ortiz, Hernan; Bentes, Carla; Bicciato, Giulio; Brigo, Francesco; Conrad, Julian; Dohler, Nico; Duncan, John S et al.
DOI: 10.1001/jamaneurol.2023.0611

Wall enhancement as a biomarker of intracranial aneurysm instability: a histo-radiological study.

PMID: 37589724
Journal: ACTA NEUROCHIRURGICA
Year: 2023
Reference: Acta Neurochir (Wien). 2023 Aug 17. doi: 10.1007/s00701-023-05739-8.
Impact factor:
Publication type: Paper in international publication
Authors: Arikan, Fuat; Coscojuela, Pilar; De Barros, Andrea; Dinia, Lavinia; Gandara, Dario; Gramegna, Laura Ludovica; Hernandez, David; Luzi, Michele; Martinez-Saez, Elena; Quintana, Manuel et al.
DOI: 10.1007/s00701-023-05739-8

Response: "Which is the risk of unprovoked seizures after acute symptomatic status epilepticus?".

PMID: 37804071
Journal: EPILEPSIA
Year: 2023
Reference: Epilepsia. 2023 Oct 7. doi: 10.1111/epi.17790.
Impact factor:
Publication type: Letter or abstract
Authors: Abraira, Laura; Abraira, Laura; Campos-Fernandez, Daniel; Fonseca, Elena; Fonseca, Elena; Gomez-Dabo, Laura; Lallana, Sofia; Quintana, Manuel; Quintana, Manuel; Rodrigo-Gisbert, Marc et al.
DOI: 10.1111/epi.17790

Implications of starting antiepileptic treatment prior to electroencephalography in first epileptic seizures.

PMID: 37858895
Journal: Neurologia
Year: 2023
Reference: Neurologia (Engl Ed). 2023 Oct 17:S2173-5808(23)00054-8. doi: 10.1016/j.nrleng.2021.02.010.
Impact factor:
Publication type: Paper in international publication
Authors: Abraira, L; Ballve, A; Campos, D; Costa E Silva, Matheus; Dienstmann, Rodrigo; Fonseca, E; Gil Ferreira, Carlos; Llaurado, A; Lopes David, Bruna Bianca; Nazareth Aguiar Junior, Pedro et al.
DOI: 10.1016/j.nrleng.2021.02.010

Interictal brain activity changes in temporal lobe epilepsy: A quantitative electroencephalogram analysis.

PMID: 34687043
Journal: ACTA NEUROLOGICA SCANDINAVICA
Year: 2022
Reference: Acta Neurol Scand. 2022 Feb;145(2):239-248. doi: 10.1111/ane.13543. Epub 2021 Oct 22.
Impact factor: 3.209
Publication type: Paper in international publication
Authors: Fonseca, Elena; Quintana, Manuel; Seijo-Raposo, Ivan; Ortiz de Zarate, Zurine; Abraira, Laura; Santamarina, Estevo; Toledo, Manuel; Alvarez-Sabin, Jose et al.
DOI: 10.1111/ane.13543

Epileptic seizures in the emergency room: clinical and electroencephalographic findings associated with brain perfusion patterns on computed tomography.

PMID: 35152335
Journal: JOURNAL OF NEUROLOGY
Year: 2022
Reference: J Neurol. 2022 Jul;269(7):3761-3769. doi: 10.1007/s00415-022-11005-1. Epub 2022 Feb 13.
Impact factor: 4.849
Publication type: Paper in international publication
Authors: Coscojuela, P; Fonseca, E; Quintana, M; Sarria-Estrada, S; Santamarina, E; Abraira, L; Sueiras, M; Thonon, V; Alvarez-Sabin, J; Toledo, M et al.
DOI: 10.1007/s00415-022-11005-1

'Leukodystrophy-Like' Phenotype in anti-MOG antibody-associated disorders.

PMID: 35030636
Journal: NEUROPEDIATRICS
Year: 2022
Reference: Neuropediatrics. 2022 Apr;53(2):147-148. doi: 10.1055/a-1740-9649. Epub 2022 Jan 14.
Impact factor: 1.947
Publication type: Paper in international publication
Authors: Gomez-Andres, David, Armangue, Thais, Sanchez-Montanez, Angel, Ortiz de Zarate Caballero, Zurine, Felipe-Rucian, Ana et al.
DOI: 10.1055/a-1740-9649

Implications of initiating antiseizure drugs prior to the performance of EEG in first epileptic seizures.

PMID: 33875301
Journal: NEUROLOGIA
Year: 2021
Reference: Neurologia (Engl Ed). 2021 Apr 16. pii: S0213-4853(21)00053-0. doi: 10.1016/j.nrl.2021.02.014.
Impact factor: 3.109
Publication type: Paper in national publication
Authors: Llaurado, A, Quintana, M, Fonseca, E, Abraira, L, Toledo, M, Requena, M, Olive, M, Ballve, A, Campos, D, Sueiras, M et al.
DOI: 10.1016/j.nrl.2021.02.014

Thesis

Carga asistencial, mortalidad y coste de la epilepsia desde su diagnóstico en pacientes adultos. Factores asociados tras un seguimiento a largo plazo.

PhD student: Manuel Quintana Luque
Director/s: Manuel Toledo Argany, José Alvarez Sabin
University:
Year: 2022

ESTUDIO DE LOS CAMBIOS EN VOLUMETRÍA CEREBRAL EN PACIENTES CON EPILEPSIA Y SU RELACIÓN CON LA ESFERA COGNITIVO-CONDUCTUAL

PhD student: Elena Fonseca Hernandez
Director/s: José Alvarez Sabin
University: Universidad Autònoma de Barcelona
Year: 2021

Job offers

Clinical Researcher-Research Group on Status Epilepticus and Acute Seizures.
Start date:
19/12/2023
End date:
01/01/2024
Document: Download
Clinical Researcher-Research Group on Status Epilepticus and Acute Seizures.
Start date:
12/06/2023
End date:
26/06/2023
Document: Download
Clinical Trial Coordinator-Research Group on Status Epilepticus and Acute Seizures.
Start date:
16/06/2022
End date:
30/06/2022
Document: Download