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Stroke Research

The search for quality and innovation has always been an inherent part of the activity of the Stroke Research Group and represents the common thread that leads us to excellence and continuous improvement.

In recent years, the Stroke Research Group has established itself as a leader in the management, recruitment and international coordination of multicenter clinical trials, as well as in the development of patents for new thrombectomy devices and the creation of new technological solutions and digital platforms to improve the diagnosis, treatment and follow-up of stroke patients. Robust strategic alliances have also been consolidated with public and private entities that ensure the viability and scalability of the research projects initiated in our group.

The Stroke Research Group is made up of a transversal and multidisciplinary team that shares a common idea: to contribute from its area of knowledge to the care and management of stroke through the effective transfer of knowledge and the complementarity of the processes of clinical research.

Team

Maria Victoria Sala Sanz de Madrid

Maria Victoria Sala Sanz de Madrid

Administration and Management
Stroke research
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Paredes Deiros, Carolina

Paredes Deiros, Carolina

Research technician
Stroke research
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Renato Simonetti

Renato Simonetti

Predoctoral researcher
Stroke research
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Rivera Sanchez, Laura

Rivera Sanchez, Laura

Administration and Management
Stroke research
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Alejandro Tomasello Weitz

Alejandro Tomasello Weitz

Stroke research
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Alvaro Garcia Tornel Garcia Camba

Alvaro Garcia Tornel Garcia Camba

Senior researcher
Stroke research
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Maria Victoria Sala Sanz de Madrid

Maria Victoria Sala Sanz de Madrid

Administration and Management
Stroke research
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Paredes Deiros, Carolina

Paredes Deiros, Carolina

Research technician
Stroke research
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Renato Simonetti

Renato Simonetti

Predoctoral researcher
Stroke research
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Rivera Sanchez, Laura

Rivera Sanchez, Laura

Administration and Management
Stroke research
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Alejandro Tomasello Weitz

Alejandro Tomasello Weitz

Stroke research
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Alvaro Garcia Tornel Garcia Camba

Alvaro Garcia Tornel Garcia Camba

Senior researcher
Stroke research
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Research lines

Innovation in clinical processes for cerebral reperfusion

Responsible: Dr. Carlos Molina

IP: -

Innovation in clinical research nursing processes in stroke

Responsible: Dra. Estela Sanjuan

IP: -

Innovation platforms in communication technology and telemedicine

Responsible: Dr. Marc Ribo

IP: -

Innovative designs and implementation of clinical trials in stroke

Responsible: Dr. Carlos Molina

IP: -

Projects

Development and validation of an artificial intelligence model for the prehospital management of patients with a suspected acute ischemic stroke

IP: Marc Ribó Jacobi
Collaborators: Alvaro Garcia Tornel Garcia Camba, Judit Álvarez González
Funding agency: Instituto de Salud Carlos III
Funding: 180000
Reference: JR22/00046
Duration: 01/01/2023 - 31/12/2026

HARMONICS. Harmonization and Implementation of High Value Stroke Care

IP: Carlos Molina Cateriano
Collaborators: Maria Baladas Orti, Ester Sanchez Gavilan, Cristina Guirao Martinez, Estefania Montiel, Marina Jimenez Iglesias, Lidia Garcia Guillamón, Judith Cendrero Correa, Federica Rizzo, Marta Aurora Rubiera Del Fueyo, David Rodriguez Luna, Renato Simonetti
Funding agency: EUROPEAN COMMISSION
Funding: 468090
Reference: HARMONICS_EIT-HEALTH-BP2022
Duration: 01/01/2022 - 31/12/2024

Clinical trial to evaluate the administration of ApTOLL in ambulances and the neuroprotective effect in stroke patients. RACETOLL

IP: Marc Ribó Jacobi
Collaborators: Marta Aurora Rubiera Del Fueyo, Carlos Molina Cateriano, Federica Rizzo
Funding agency: Ministerio de Ciencia e Innovación-MICINN
Funding: 437334
Reference: CPP2021-008378
Duration: 01/03/2022 - 28/02/2025

Ministerio de Ciencia

Caracterización de la DIScapacidad y la COgnición en sujetos con Esclerosis múltiple a partir de secuencias de Resonancia magnética convencional (DISCOvER).

IP: Deborah Pareto Onghena
Collaborators: Ingrid Galán Cartaña, Juan Fco. Corral Gamez, Herena Eixarch Ahufinger, M Jesus Arevalo Navines, Andrea De Barros Figueredo, Neus Mongay Ochoa, Giorgio Colangelo
Funding agency: Instituto de Salud Carlos III
Funding: 87120
Reference: PI22/01709
Duration: 01/01/2023 - 31/12/2025

Publications

Derivation and validation of three intracerebral hemorrhage expansion scores using different CT modalities.

PMID: 37059906
Journal: EUROPEAN RADIOLOGY
Year: 2023
Reference: Eur Radiol. 2023 Sep;33(9):6045-6053. doi: 10.1007/s00330-023-09621-0. Epub 2023 Apr 15.
Impact factor:
Publication type: Paper in international publication
Authors: Boned, Sandra; Boned, Sandra; Coscojuela, Pilar; Coscojuela, Pilar; Garcia-Tornel, Alvaro; Garcia-Tornel, Alvaro; Juega, Jesus M; Juega, Jesus M; Lozano, Prudencio; Molina, Carlos A et al.
DOI: 10.1007/s00330-023-09621-0

Cryptogenic stroke as a working diagnosis: the need for an early and comprehensive diagnostic work-up.

PMID: 37060045
Journal: BMC Neurology
Year: 2023
Reference: BMC Neurol. 2023 Apr 14;23(1):153. doi: 10.1186/s12883-023-03206-6.
Impact factor:
Publication type: Letter or abstract
Authors: Acampa, Maurizio; Lattanzi, Simona; Lazzerini, Pietro Enea; Rubiera, Marta et al.
DOI: 10.1186/s12883-023-03206-6

Neurophysiological monitoring during endovascular treatment of brain arteriovenous malformations: A meta-analysis.

PMID: 37170611
Journal: INTERVENTIONAL NEURORADIOLOGY
Year: 2023
Reference: Interv Neuroradiol. 2023 May 11:15910199231175195. doi: 10.1177/15910199231175195.
Impact factor:
Publication type: Review in international publication
Authors: Abdalkader, Mohamad; Caroff, Jildaz; Cuevas, Jose Luis; Da Ros, Valerio; Diana, Francesco; Forestier, Geraud; Hernandez, David; Hernandez, David; Lascuevas, Marta De Dios; Mounayer, Charbel et al.
DOI: 10.1177/15910199231175195

Sex and gender differences in acute stroke care: metrics, access to treatment and outcome. A territorial analysis of the Stroke Code System of Catalonia.

PMID: 37231687
Journal: European Stroke Journal
Year: 2023
Reference: Eur Stroke J. 2023 Jun;8(2):557-565. doi: 10.1177/23969873231156260. Epub 2023 Mar 2.
Impact factor:
Publication type: Paper in international publication
Authors: Abilleira, Sonia; Almendros, Mari Cruz; Canovas, David; Carrion, Dolors; Catena, Esther; Cocho, Dolores; Colom, Carla; Costa, Xavier; Deulofeu, Anna; Diaz, Gloria et al.
DOI: 10.1177/23969873231156260

Mechanical thrombectomy with a novel device: initial clinical experience with the ANATM thrombectomy device.

PMID: 33340641
Journal: JOURNAL OF NEURORADIOLOGY
Year: 2022
Reference: J Neuroradiol. 2022 Jun;49(4):324-328. doi: 10.1016/j.neurad.2020.11.003. Epub 2020 Dec 16.
Impact factor: 2.423
Publication type: Paper in international publication
Authors: Ribo, Marc; Tomasello, Alejandro; Hernandez, David; Requena, Manuel; Liebeskind, David S; Nogueira, Raul G; Jovin, Tudor; Andersson, Tommy; Cognard, Christoph; Siddiqui, Adnan et al.
DOI: 10.1016/j.neurad.2020.11.003

Correction to: Increased Number of Passes and Double Stent Retriever Technique Induces Cumulative Injury on Arterial Wall After Mechanical Thrombectomy in a Swine Model.

PMID: 35749034
Journal: Translational Stroke Research
Year: 2022
Reference: Transl Stroke Res. 2022 Jun 24. pii: 10.1007/s12975-022-01054-z. doi: 10.1007/s12975-022-01054-z.
Impact factor: 6.829
Publication type: Letter or abstract
Authors: Tomasello, Alejandro; Ribo, Marc; Gil, Alberto; Li, Jiahui; Esteves, Marielle; Coscojuela, Pilar; de Dios, Marta; Pinana, Carlos; Requena, Manuel; Gramegna, Laura Ludovica et al.
DOI: 10.1007/s12975-022-01054-z

Experience and results after the implementation of a radiology day unit in a reference hospital.

PMID: 35767122
Journal: Insights into Imaging
Year: 2022
Reference: Insights Imaging. 2022 Jun 29;13(1):109. doi: 10.1186/s13244-022-01251-2.
Impact factor: 5.231
Publication type: Paper in international publication
Authors: Escobar, Manuel; Tomasello, Alejandro; Perez Lafuente, Mercedes; Andreu, Jordi; Grinon, Jesus; Sanchez-Tirado, Cristina; Mast, Richard; Antolin, Andreu; Roson, Nuria et al.
DOI: 10.1186/s13244-022-01251-2

International Controlled Study of Revascularization and Outcomes Following COVID-Positive Mechanical Thrombectomy.

PMID: 35818781
Journal: EUROPEAN JOURNAL OF NEUROLOGY
Year: 2022
Reference: Eur J Neurol. 2022 Jul 12. doi: 10.1111/ene.15493.
Impact factor: 6.089
Publication type: Paper in international publication
Authors: Youssef, Patrick P, Pandey, Aditya S, Sweid, Ahmad, Piotin, Michel, Bekelis, Kimon, Sourour, Nader, Raz, Eytan, Vela-Duarte, Daniel, Linfante, Italo, Dabus, Guilherme et al.
DOI: 10.1111/ene.15493

Direct to Angiography Suite Without Stopping for Computed Tomography Imaging for Patients With Acute Stroke: A Randomized Clinical Trial.

PMID: 34338742
Journal: JAMA Neurology
Year: 2021
Reference: JAMA Neurol. 2021 Sep 1;78(9):1099-1107. doi: 10.1001/jamaneurol.2021.2385.
Impact factor: 18.302
Publication type: Paper in international publication
Authors: Requena, Manuel, Olive-Gadea, Marta, Muchada, Marian, Hernandez, David, Rubiera, Marta, Boned, Sandra, Pinana, Carlos, Deck, Matias, Garcia-Tornel, Alvaro, Diaz-Silva, Humberto et al.
DOI: 10.1001/jamaneurol.2021.2385

Automated Perfusion Calculations vs. Visual Scoring of Collaterals and CBV-ASPECTS : Has the Machine Surpassed the Eye?

PMID: 33216157
Journal: Clinical Neuroradiology
Year: 2021
Reference: Clin Neuroradiol. 2021 Jun;31(2):499-506. doi: 10.1007/s00062-020-00974-3. Epub 2020 Nov 20.
Impact factor: 3.649
Publication type: Paper in international publication
Authors: Kabiri, Reza, Flottmann, Fabian A, Menon, Bijoy K, Horn, Mackenzie, Liebeskind, David S, Honda, Tristan, Ribo, Marc, Ruiz, Manuel Requena, Kabbasch, Christoph, Lichtenstein, Thorsten et al.
DOI: 10.1007/s00062-020-00974-3

Direct to Angiography vs Repeated Imaging Approaches in Transferred Patients Undergoing Endovascular Thrombectomy.

PMID: 34125153
Journal: JAMA Neurology
Year: 2021
Reference: JAMA Neurol. 2021 Aug 1;78(8):916-926. doi: 10.1001/jamaneurol.2021.1707.
Impact factor: 18.302
Publication type: Paper in international publication
Authors: Maali, Laith, Radaideh, Yazan, Reddy, Sujan Teegala, Parsha, Kaushik Niranjan, Alenzi, Bader, Abdulrazzak, Mohammad Ammar, Greco, Jonathan, Hoit, Daniel, Martin-Schild, Sheryl B, Song, Sarah et al.
DOI: 10.1001/jamaneurol.2021.1707

EXPRESS: Cerebrovascular events and outcomes in hospitalized patients with COVID-19: The SVIN COVID-19 Multinational Registry.

PMID: 32852257
Journal: International Journal of Stroke
Year: 2021
Reference: Int J Stroke. 2021 Jun;16(4):437-447. doi: 10.1177/1747493020959216. Epub 2020 Sep 30.
Impact factor: 5.266
Publication type: Paper in international publication
Authors: Siegler, James E, Cardona, Pere, Arenillas, Juan F, Talavera, Blanca, Nunez Guillen, Ana, Chavarria-Miranda, Alba, De Lera, Mercedes, Khandelwal, Priyank, Bach, Ivo, Patel, Pratit et al.
DOI: 10.1177/1747493020959216

How soon should urgent EEG be performed following a first epileptic seizure?

PMID: 32694039
Journal: EPILEPSY & BEHAVIOR
Year: 2020
Reference: Epilepsy Behav. 2020 Oct;111:107315. doi: 10.1016/j.yebeh.2020.107315. Epub 2020 Jul 18.
Impact factor: 2.508
Publication type: Paper in international publication
Authors: Toledo, M, Quintana, M, Abraira, L, Llaurado, A, Santamarina, E, Fonseca, E, Olive, M, Requena, M, Sueiras, M, Guzman, L et al.
DOI: 10.1016/j.yebeh.2020.107315

Preliminary Experience Using a Covered Stent Graft in Patients with Acute Ischemic Stroke and Carotid Tandem Lesion.

PMID: 32676962
Journal: CARDIOVASCULAR AND INTERVENTIONAL RADIOLOGY
Year: 2020
Reference: Cardiovasc Intervent Radiol. 2020 Nov;43(11):1679-1686. doi: 10.1007/s00270-020-02594-3. Epub 2020 Jul 16.
Impact factor: 2.034
Publication type: Paper in international publication
Authors: Pinana, Carlos, Gramegna, Laura Ludovica, Folleco, Edgar, Requena, Manuel, Hernandez, David, Tomasello Weitz, Alejandro et al.
DOI: 10.1007/s00270-020-02594-3

Screening of Embolic Sources by Point-of-Care Ultrasound in the Acute Phase of Ischemic Stroke.

PMID: 32532655
Journal: ULTRASOUND IN MEDICINE AND BIOLOGY
Year: 2020
Reference: Ultrasound Med Biol. 2020 Sep;46(9):2173-2180. doi: 10.1016/j.ultrasmedbio.2020.05.009. Epub 2020 Jun 10.
Impact factor: 2.514
Publication type: Paper in international publication
Authors: Juega, Jesus, Pagola, Jorge, Gonzalez-Alujas, Teresa, Rodriguez-Luna, David, Rubiera, Marta, Rodriguez-Villatoro, Noelia, Garcia-Tornel, Alvaro, Requena, Manuel, Deck, Matias, Sero, Laia et al.
DOI: 10.1016/j.ultrasmedbio.2020.05.009

Mechanical thrombectomy with a novel stent retriever with multifunctional zones: Initial Clinical Experience with the NeVa thrombectomy device.

PMID: 30951765
Journal: JOURNAL OF NEURORADIOLOGY
Year: 2020
Reference: J Neuroradiol. 2020 Jun;47(4):301-305. doi: 10.1016/j.neurad.2019.03.007. Epub 2019 Apr 2.
Impact factor: 2.423
Publication type: Paper in international publication
Authors: Ribo, M, Requena, M, Macho, J, Zamarro, J, Machi, P, Hernandez, D, Blasco, J, Tomasello, A et al.
DOI: 10.1016/j.neurad.2019.03.007

When to Stop.

PMID: 31177974
Journal: STROKE
Year: 2019
Reference: Stroke. 2019 Jul;50(7):1781-1788. doi: 10.1161/STROKEAHA.119.025088. Epub 2019 Jun 10.
Impact factor: 6.046
Publication type: Paper in international publication
Authors: Olive-Gadea, Marta, Garcia-Tornel, Alvaro, Requena, Manuel, Rubiera, Marta, Muchada, Marian, Pagola, Jorge, Rodriguez-Luna, David, Deck, Matias, Juega, Jesus, Rodriguez-Villatoro, Noelia et al.
DOI: 10.1161/STROKEAHA.119.025088

Farmalarm: Application for Mobile Devices Improves Risk Factor Control After Stroke

PMID: 31167621
Journal: STROKE
Year: 2019
Reference: Stroke. 2019 Jul;50(7):1819-1824. doi: 10.1161/STROKEAHA.118.024355. Epub 2019 Jun 6.
Impact factor: 6.046
Publication type: Paper in international publication
Authors: Juega, Jesus, Garcia-Tornel, Alvaro, Rodriguez-Luna, David, Pagola, Jorge, Rubiera, Marta, Molina, Carlos A, Ribo, Marc, Rodriguez-Villatoro, Noelia, Lopez, Rosa, Boned, Sandra et al.
DOI: 10.1161/STROKEAHA.118.024355

Predictors of response to endovascular treatment of posterior circulation stroke.

PMID: 31153569
Journal: EUROPEAN JOURNAL OF RADIOLOGY
Year: 2019
Reference: Eur J Radiol. 2019 Jul;116:219-224. doi: 10.1016/j.ejrad.2019.05.001. Epub 2019 May 2.
Impact factor: 2.948
Publication type: Paper in international publication
Authors: Tomasello, Alejandro, Molina, Carlos, Rovira, Alex, Rubiera, Marta, Gramegna, Laura Ludovica, Requena, Manuel, Dinia, Lavinia, Melendez, Fernando, Hernandez, David, Coscojuela, Pilar et al.
DOI: 10.1016/j.ejrad.2019.05.001

Outcome, efficacy and safety of endovascular thrombectomy in ischaemic stroke according to time to reperfusion: data from a multicentre registry.

PMID: 30944585
Journal: Therapeutic Advances in Neurological Disorders
Year: 2019
Reference: Ther Adv Neurol Disord. 2019 Mar 27;12:1756286419835708. doi: 10.1177/1756286419835708. eCollection 2019.
Impact factor: 3.58
Publication type: Paper in international publication
Authors: Gralla, Jan, Meinel, Thomas Raphael, Kaesmacher, Johannes, Mordasini, Pasquale, Mosimann, Pascal J, Jung, Simon, Arnold, Marcel, Heldner, Mirjam Rachel, Michel, Patrik, Hajdu, Steven D et al.
DOI: 10.1177/1756286419835708

Blog

News

The Consortium will create a platform to facilitate a personalised management for stroke patients, enabling a more efficient personalized monitoring and patient follow up.

Funding is key to bringing the neuroprotective drug ApTOLL to market and providing a new therapeutic option for the patients.

The award is a recognition for his significant contribution to the development of research in multiple sclerosis within the Catalan Institute of Health.

Job offers

Research engineer - Medical Image & AI
Start date:
23/10/2023
End date:
26/11/2023
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Research Nurse/ Study Coordinator_20h/week
Start date:
03/07/2023
End date:
19/07/2023
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Research Nurse/ Study Coordinator_40h/week
Start date:
03/07/2023
End date:
19/07/2023
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