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03/07/2014

VHIR and the Probitas Foundation install in Angola the first automatic system to diagnose multidrug-resistant tuberculosis

2014_0152_2014_0152_IMATGE

03/07/2014

With the GenXpert, results are available in less than two hours

The Vall d’Hebron Institute of Research (VHIR) and the "http://www.fundacionprobitas.org/?lang=en" Probitas Foundation implemented in the "http://hospitalnsdelapaz.blogspot.com.es/" Nossa Senhora da Paz Hospital in Cubal, in the east central part of Angola, a fast and automatic genotypic test that will, for the first time in the country, diagnose tuberculosis and determine whether is multidrug-resistant. The Xpert MTB/RIF (GenXpert Cepheid) equipment can identify the disease with sputum samples in 1 hour 45 minutes. With the incorporation of this technology, the diagnostic time of multidrug-resistant tuberculosis will be remarkably reduced: until now the diagnostic was done by clinical suspicion or after microbiological failure in the 5th month of the treatment. Dr. Israel Molina, director of the International Health Programme of the Catalan Institute of Health (PROSICS) and researcher of the Infectious Diseases group at VHIR, is convinced that “the patient’s survival rate will improve because the treatment will be administered sooner, and for that reason, the time of contagiousness will be also reduced”.The researchers of the Microbiology group at VHIR, led by Dr. Tomàs Pumarola, will receive over 500 samples from the hospital in Cubal in order to undertake a pioneer study on the prevalence of multidrug-resistant tuberculosis in the area. They will analyze the drug sensitivity through conventional means, following the recommended flow chart. The epidemiological knowledge of multidrug-resistant tuberculosis will help to establish therapeutic guidelines with the aim to reduce the morbidity and mortality rate of the disease within the area. The World Health Organization have recommended since 2010 the GenXpert system to diagnose tuberculosis, a disease that in Angola affects 300 out of 100.000 inhabitants and has a cure rate of the 70%, one of the worst in Africa. With the arrival of the technology to the hospital, the equipment and the knowledge of the professionals from Vall d’Hebron and PROSICS will be transferred and kept by the local partner that will integrate the system in the national public health network.The project is a part of the collaboration with the national program against tuberculosis. The Angolan government will provide the second-line drugs which are needed for the treatment of the patients diagnosed.

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