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Growth and Development

Our group is dedicated to paediatric research. We are interested in rare respiratory and endocrinological diseases, and also in common paediatric problems such as normal growth, asthma, neonatal pathology and imaging diagnosis, as well as minority diseases. Our goal is to transfer the findings of clinical and genetic studies to the widespread clinical practice and the general population, with the long-term objective of obtaining better diagnoses, implementing better therapeutic practices and improving the health of children.

Our group is part of CIBERER (Biomedical Research Networking Centre on Rare Diseases) (CIBERER U712) and European Reference Networks (ERN) for rare diseases ERN LUNG and Endo-ERN.

Team

Nuria  Servalls Rozas

Nuria Servalls Rozas

Growth and Development
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Rocio  Lecegui  Alfonso

Rocio Lecegui Alfonso

Administration and Management
Growth and Development
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SILVIA GARTNER TIZZANO

SILVIA GARTNER TIZZANO

Main researcher
Growth and Development
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Nuria  Servalls Rozas

Nuria Servalls Rozas

Growth and Development
Read more
Rocio  Lecegui  Alfonso

Rocio Lecegui Alfonso

Administration and Management
Growth and Development
Read more
SILVIA GARTNER TIZZANO

SILVIA GARTNER TIZZANO

Main researcher
Growth and Development
Read more

Publications

Addressing the unmet needs in patients with type 2 inflammatory diseases: when quality of life can make a difference.

PMID: 38026127
Journal:
Year: 2023
Reference: Front Allergy. 2023 Nov 9;4:1296894. doi: 10.3389/falgy.2023.1296894. eCollection 2023.
Impact factor:
Publication type: Paper in international publication
Authors: Aceituno-Lopez, Maria Angeles; Alobid, Isam; Camprodon-Gomez, Maria; Del-Toro-Riera, Mireia; Espinosa, Miriam; Gomez de la Fuente, Enrique; Lara-Fernandez, Roser; Luca de Tena, Africa; Marti-Beltran, Sergi; Moreno-Galdo, Antonio et al.
DOI: 10.3389/falgy.2023.1296894

Geographic distribution and phenotype of European people with cystic fibrosis carrying A1006E mutation.

PMID: 35032736
Journal: RESPIRATORY MEDICINE
Year: 2022
Reference: Respir Med. 2022 Feb;192:106736. doi: 10.1016/j.rmed.2022.106736. Epub 2022 Jan 6.
Impact factor: 3.415
Publication type: Paper in international publication
Authors: Calderazzo, Maria Adelaide, Pizzamiglio, Giovanna, Castillo-Corullon, Silvia, Alvarez-Fernandez, Antonio, Gartner, Silvia, Padoan, Rita, Carnovale, Vincenzo, Salvatore, Marco, Moya-Quiles, M feminine Rosa, Orenti, Annalisa et al.
DOI: 10.1016/j.rmed.2022.106736

Transition of adolescents with severe asthma from pediatric to adult care in Spain: the STAR consensus.

PMID: 35029151
Journal: JOURNAL OF INVESTIGATIONAL ALLERGOLOGY AND CLINICAL IMMUNOLOGY
Year: 2022
Reference: J Investig Allergol Clin Immunol. 2022 Jan 12:0. doi: 10.18176/jiaci.0780.
Impact factor: 7.033
Publication type: Paper in international publication
Authors: Valverde-Molina, J, Fernandez-Nieto, M, Torres-Borrego, J, Lozano Blasco, J, de Mir-Messa, I, Blanco-Aparicio, M, Figuerola Mulet, J, Moure, A L, Sanchez-Herrero, M G, Sanchez-Garcia, S et al.
DOI: 10.18176/jiaci.0780

Diagnosis of Genetic White Matter Disorders by Singleton Whole-Exome and Genome Sequencing Using Interactome-Driven Prioritization.

PMID: 35012964
Journal: NEUROLOGY
Year: 2022
Reference: Neurology. 2022 Mar 1;98(9):e912-e923. doi: 10.1212/WNL.0000000000013278. Epub 2022 Jan 10.
Impact factor: 9.91
Publication type: Paper in international publication
Authors: Giros, Marisa, Schluter, Agatha, Rodriguez-Palmero, Agusti, Verdura, Edgard, Velez-Santamaria, Valentina, Ruiz, Montserrat, Fourcade, Stephane, Planas-Serra, Laura, Martinez, Juan Jose, Guilera, Cristina et al.
DOI: 10.1212/WNL.0000000000013278

Respiratory outcomes of "new" bronchopulmonary dysplasia in adolescents: A multicenter study.

PMID: 33314679
Journal: PEDIATRIC PULMONOLOGY
Year: 2021
Reference: Pediatr Pulmonol. 2021 May;56(5):1205-1214. doi: 10.1002/ppul.25226. Epub 2020 Dec 22.
Impact factor: 3.039
Publication type: Paper in international publication
Authors: Vidal, Roser Ayats, Perez-Tarazona, Santiago, Esteban, Santiago Rueda, Garcia, Maria Luz Garcia, Sanchez, Maria Arroyas, Messa, Ines De Mir, Valarezo, Tatiana Acevedo, Medina, Orlando Mesa, Callejon, Alicia Callejon, Calderin, Elisa Maria Canino et al.
DOI: 10.1002/ppul.25226

[Use of high flow nasal cannula in Spanish neonatal units].

PMID: 33771459
Journal: ANALES DE PEDIATRIA
Year: 2021
Reference: An Pediatr (Engl Ed). 2021 Mar 23. pii: S1695-4033(21)00145-4. doi: 10.1016/j.anpedi.2021.02.012.
Impact factor: 1.5
Publication type: Paper in national publication
Authors: Rodriguez Losada, Olalla, Montaner Ramon, Alicia, Gregoraci Fernandez, Angela, Flores Espana, Vanessa, Gros Turpin, Anna, Comunas Gomez, Juan Jose, Castillo Salinas, Felix et al.
DOI: 10.1016/j.anpedi.2021.02.012

Delineating the neurological phenotype in children with defects in the ECHS1 or HIBCH gene.

PMID: 32677093
Journal: JOURNAL OF INHERITED METABOLIC DISEASE
Year: 2021
Reference: J Inherit Metab Dis. 2021 Mar;44(2):401-414. doi: 10.1002/jimd.12288. Epub 2020 Aug 16.
Impact factor: 4.982
Publication type: Paper in international publication
Authors: Artuch, R, Dionisi-Vici, C, Gonzalez-Gutierrez-Solana, L, Correa-Vela, M, Ortigoza-Escobar, J D, Sanchez-Montanez, A, Vazquez, E, Delgado, I, Aguilera-Albesa, S, Yoldi, M E et al.
DOI: 10.1002/jimd.12288

Implementation of a Gene Panel for Genetic Diagnosis of Primary Ciliary Dyskinesia.

PMID: 32253119
Journal: ARCHIVOS DE BRONCONEUMOLOGIA
Year: 2021
Reference: Arch Bronconeumol. 2021 Mar;57(3):186-194. doi: 10.1016/j.arbres.2020.02.010. Epub 2020 Apr 3.
Impact factor: 4.872
Publication type: Paper in national publication
Authors: Baz-Redon, Noelia, Fernandez-Cancio, Monica, Moreno-Galdo, Antonio, Camats-Tarruella, Nuria, Tizzano, Eduardo, Amaro-Rodriguez, Rosanel, Rovira-Amigo, Sandra, Paramonov, Ida, Castillo-Corullon, Silvia, Cols Roig, Maria et al.
DOI: 10.1016/j.arbres.2020.02.010

Less Invasive Surfactant Administration in Spain: A Survey Regarding Its Practice, the Target Population, and Premedication Use.

PMID: 30716788
Journal: AMERICAN JOURNAL OF PERINATOLOGY
Year: 2020
Reference: Am J Perinatol. 2020 Feb;37(3):277-280. doi: 10.1055/s-0039-1678534. Epub 2019 Feb 4.
Impact factor: 1.474
Publication type: Paper in international publication
Authors: Fernandez, Cristina, Boix, Hector, Camba, Fatima, Comunas, Juan Jose, Castillo, Felix et al.
DOI: 10.1055/s-0039-1678534

[Graves disease with negative TSH receptor antibodies: A presentation of 5 cases].

PMID: 32094085
Journal: ANALES DE PEDIATRIA
Year: 2020
Reference: An Pediatr (Barc). 2020 Dec;93(6):417-419. doi: 10.1016/j.anpedi.2020.01.008. Epub 2020 Feb 21.
Impact factor: 1.313
Publication type: Letter whit IF
Authors: Scatti Regas, Aina, Pujol Borrell, Ricard, Ferrer Costa, Roser, Puerto Carranza, Elsa, Clemente Leon, Maria et al.
DOI: 10.1016/j.anpedi.2020.01.008

Molecular basis of CYP19A1 deficiency in a 46, XX patient with R550W mutation in POR: Expanding the PORD phenotype.

PMID: 32060549
Journal: JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
Year: 2020
Reference: J Clin Endocrinol Metab. 2020 Apr 1;105(4). pii: 5736381. doi: 10.1210/clinem/dgaa076.
Impact factor: 5.399
Publication type: Paper in international publication
Authors: Udhane, Sameer S, Parween, Shaheena, Fernandez-Cancio, Monica, Benito-Sanz, Sara, Camats, Nuria, Velazquez, Maria Natalia Rojas, Lopez-Siguero, Juan-Pedro, Audi, Laura, Pandey, Amit V, Fluck, Christa E et al.
DOI: 10.1210/clinem/dgaa076

Pediatric minor head injury imaging practices: results from an ESPR survey.

PMID: 31828360
Journal: NEURORADIOLOGY
Year: 2020
Reference: Neuroradiology. 2020 Feb;62(2):251-255. doi: 10.1007/s00234-019-02326-6. Epub 2019 Dec 11.
Impact factor: 2.238
Publication type: Paper in international publication
Authors: Argyropoulou, Maria I, Alexiou, George A, Xydis, Vassileios G, Adamsbaum, Catherine, Chateil, Jean-Francois, Rossi, Andrea, Girard, Nadine, Vazquez, Elida, Astrakas, Loukas G et al.
DOI: 10.1007/s00234-019-02326-6

[Pubertal growth of 1,453 healthy children according to age at pubertal growth spurt onset. The Barcelona longitudinal growth study].

PMID: 29475798
Journal: ANALES DE PEDIATRIA
Year: 2018
Reference: An Pediatr (Barc). 2018 Sep;89(3):144-152. doi: 10.1016/j.anpedi.2017.11.018. Epub 2018 Feb 21.
Impact factor: 1.318
Publication type: Paper in national publication
Authors: Carrascosa, Antonio, Yeste, Diego, Moreno-Galdo, Antonio, Gussinye, Miquel, Ferrandez, Angel, Clemente, Maria, Fernandez-Cancio, Monica et al.
DOI: 10.1016/j.anpedi.2017.11.018

Progress in Definition, Prevention and Treatment of Fungal Infections in Cystic Fibrosis.

PMID: 28762125
Journal: MYCOPATHOLOGIA
Year: 2018
Reference: Mycopathologia. 2018 Feb;183(1):21-32. doi: 10.1007/s11046-017-0182-0. Epub 2017 Jul 31.
Impact factor: 1.476
Publication type: Review in national publication
Authors: Barry, Peter James, Schwarz, Carsten, Hartl, Dominik, Eickmeier, Olaf, Hector, Andreas, Benden, Christian, Durieu, Isabelle, Sole, Amparo, Gartner, Silvia, Milla, Carlos E et al.
DOI: 10.1007/s11046-017-0182-0

Invasive Pulmonary Fungal Infections in Cystic Fibrosis.

PMID: 28864921
Journal: MYCOPATHOLOGIA
Year: 2018
Reference: Mycopathologia. 2018 Feb;183(1):33-43. doi: 10.1007/s11046-017-0199-4. Epub 2017 Sep 1.
Impact factor: 1.476
Publication type: Paper in international publication
Authors: Schwarz, Carsten, Brandt, Claudia, Whitaker, Paul, Sutharsan, Sivagurunathan, Skopnik, Heino, Gartner, Silvia, Smazny, Christina, Rohmel, Jobst F et al.
DOI: 10.1007/s11046-017-0199-4

Oral glucose tolerance test and continuous glucose monitoring to assess diabetes development in cystic fibrosis patients.

PMID: 29137964
Journal: Endocrinologia, diabetes y nutricion
Year: 2018
Reference: Endocrinol Diabetes Nutr. 2018 Jan;65(1):45-51. doi: 10.1016/j.endinu.2017.08.008. Epub 2017 Nov 12.
Impact factor: 0
Publication type: Paper in national publication
Authors: Clemente Leon, Maria, Bilbao Gasso, Laura, Moreno-Galdo, Antonio, Campos Martorrell, Ariadna, Gartner Tizzano, Silvia, Yeste Fernandez, Diego, Carrascosa Lezcano, Antonio et al.
DOI: 10.1016/j.endinu.2017.08.008

Achievement of metabolic control among children and adolescents with type 1 diabetes in Spain.

PMID: 28421336
Journal: ACTA DIABETOLOGICA
Year: 2017
Reference: Acta Diabetol. 2017 Jul;54(7):677-683. doi: 10.1007/s00592-017-0991-0. Epub 2017 Apr 18.
Impact factor: 3.34
Publication type: Paper in international publication
Authors: Rica, Itxaso, Mingorance, Andres, Gomez-Gila, Ana Lucia, Clemente, Maria, Gonzalez, Isabel, Caimari, Maria, Garcia-Cuartero, Beatriz, Barrio, Raquel et al.
DOI: 10.1007/s00592-017-0991-0

Discordant Genotypic Sex and Phenotype Variations in Two Spanish Siblings with 17alpha-Hydroxylase/17,20-Lyase Deficiency Carrying the Most Prevalent Mutated CYP17A1 Alleles of Brazilian Patients.

PMID: 28376482
Journal: Sexual Development
Year: 2017
Reference: Sex Dev. 2017;11(2):70-77. doi: 10.1159/000468160. Epub 2017 Apr 4.
Impact factor: 1.972
Publication type: Paper in international publication
Authors: Tizzano, Eduardo, Carrascosa, Antonio, Audi, Laura, Garcia-Arumi, Elena, Nishi, Mirian Y, Fernandez-Cancio, Monica, Garcia-Garcia, Emilio, Gonzalez-Cejudo, Carmen, Martinez-Maestre, Maria-Angeles, Mangas-Cruz, Miguel-Angel et al.
DOI: 10.1159/000468160

Pulmonary arterial hypertension in children after neonatal arterial switch operation.

PMID: 28115472
Journal: HEART
Year: 2017
Reference: Heart. 2017 Aug;103(16):1244-1249. doi: 10.1136/heartjnl-2016-310624. Epub 2017 Jan 23.
Impact factor: 6.059
Publication type: Paper in international publication
Authors: Berger, Rolf Mf, Zijlstra, Willemijn Mh, Elmasry, Ola, Pepplinkhuizen, Shari, Ivy, D Dunbar, Bonnet, Damien, Luijendijk, Paul, Levy, Marilyne, Gavilan, Jose Luis, Torrent-Vernetta, Alba et al.
DOI: 10.1136/heartjnl-2016-310624

Diagnosis of Cystic Fibrosis in Screened Populations.

PMID: 28129810
Journal: JOURNAL OF PEDIATRICS
Year: 2017
Reference: J Pediatr. 2017 Feb;181S:S33-S44.e2. doi: 10.1016/j.jpeds.2016.09.065.
Impact factor: 3.874
Publication type: Clinical guide
Authors: Blau, Hannah, Gartner, Silvia, McColley, Susanna A, Sermet-Gaudelus, Isabelle, Wilschanski, Michael, Rock, Michael J, Farrell, Philip M, White, Terry B, Howenstine, Michelle S, Munck, Anne et al.
DOI: 10.1016/j.jpeds.2016.09.065

Blog

News

Es va reconèixer la tasca de més de 70 professionals dedicades a aquesta malaltia pulmonar, tant assistencial com de recerca.

The two studies awarded has been the research for a the ciliary dyskinesia diagnosis led by the VHIR’s Growth and Development Group and the EPISCAN II, in which Dr. Miravitlles has participated.

An international clinical trial has demonstrated the effectiveness of dupilumab in reducing patients’ asthmatic exacerbations, improving their and their relatives quality of life