About the VHIR
Here at the Vall d'Hebron Research Institute (VHIR) we promote biomedical research, innovation and teaching. Over 1,800 people are seeking to understand diseases today so the treatment can be improved tomorrow.
Research
We are working to understand diseases, to find out how they operate and to create better treatments for patients. Get to know about our groups and their lines of research.
People
People are the centre of the Vall d'Hebron Research Institute (VHIR). This is why we are bound by the principles of freedom of research, gender equality and professional attitudes that HRS4R promotes.
Clinical trials
Our work is not just basic or translational; we are leaders in clinical research. Enter and find about the clinical trials we are conducting and why we are a world reference in this field.
Progress
Our aim is to make the research carried out at the Vall d’Hebron Research Institute (VHIR) a driving force for transformation. How? By identifying new channels and solutions for the promotion of people's health and well-being.
Core facilities
We offer specialist support for researchers, internal and external alike, ranging from specific services to preparing complete projects. All this, from a perspective of quality and speed of response.
News
We offer you a gateway for staying up to date on everything going on at the Vall d’Hebron Research Institute (VHIR), from the latest news to future solidarity activities and initiatives that we are organising.
The group of Physiology and Pathophysiology of the Digestive Tract focuses its research activity on the functioning of the digestive tract as a whole, including the functions of secretion, motility, absorption and barrier both in healthy individuals and in the presence of disease. The application of knowledge to clinical practice is a priority for the group.
Research in digestive motility encompasses disorders of visceral sensitivity, the brain-gut axis and intestinal allergy. Research on inflammation also includes the pancreas.
We have also launched a cross-sectional research program that focuses on the role of the gut microbiota in inflammation and gut function.
The human microbiome is the collective genomes of all microorganisms living at the multiple sites of the human body (oral cavity, skin, nasal cavity, gastrointestinal tract (GI) and vagina). Human (Homo sapiens) and their commensal microorganisms have evolved together over the last 200,000 years and have become dependent on one another. Interaction between humans and their symbiotic bacteria is essential to many aspects of normal ‘mammalian’ physiology, ranging from metabolic activity to immune homeostasis, and ecological or genetic changes that disturb this mutualism can result in disease. It reflects the evolutionary selection pressures acting at both the levels of the host and the microbial cells and has a direct profound impact on human health. This line of research aims at understanding the role of the gut microbiome in intestinal disorders using ‘omics approaches.
Our research group proposes a service-collaboration in Microbiome analysis.
You can find further information on our prices at the following URL.
IP: Chaysavanh Manichanh
Research has been focused on the origin and mechanisms of the disorders of digestive function. Major advancements have been achieved in relation to the diagnostic methods to detect neuro-myopathic disorders of the digestive tract. Specifically, an overload test has been developed that increases the sensitivity of intestinal manometry to the detect small bowel motor dysfunction. Non-invasive evaluation of intestinal motility has been approached using an original program of endoluminal image analysis using computer learning techniques and automatic learning methods to videos obtained by means of capsule endoscopy. Furthermore, the possible mechanisms involved in symptoms without apparent cause have been investigated; specifically, the mechanism of abdominal distention has been identified by means of morpho-volumetric analysis of the abdominal; The effects of food and diet on gut function amnd perception in health and disease have been addressed.
IP: Fernando Azpiroz Vidaur
This research programme includes five projects (supported by Spanish and European public research agencies) aimed at the investigation of the cross-talk and effects of live bacteria of the gut microbiota on the intestinal mucosa. In addition, the programme includes four clinical/physiological studies that address the potential application of new knowledge gained in basic research on inflammatory bowel diseases.
IP: Francisco Guarner Aguilar
The irritable bowel syndrome (IBS), the group of microscopical enteritides, food allergy, gastrointestinal eosinophilopaties, and other functional disorders of the gastrointestinal tract represent more than 50% of digestive consultations. Clinical course is chronic and recurrent. However, sensitive and specific diagnostic biological markers are lacking and clinical management is suboptimal as well. Interestingly, a common finding in the intestine of these patients is the presence of barrier dysfunction, mucosal inflammation and immune activation. Moreover, this finding may be related to the onset and severity of some major clinical symptoms, particularly in IBS.
Therefore, our group pursues the detailed comprehension (genetic/gender, immunological, metabolic, cellular and molecular basis) of the mechanisms connecting environmental determinants (stress and infections) to the development of intestinal mucosal microscopical inflammation, with special focus in IBS.
Our approach includes experimental studies in animal models and humans as well, yet remains inherently translational in search for better targets helpful for the diagnosis, prevention and treatment of IBS and related disorders. In addition, preclinical and clinical assays are also being carried out.
IP: Fco Javier Santos Vicente
IP: Chaysavanh Manichanh Collaborators: Zaida Soler Luque, Laura Campderros Traver, Sara Vega Abellaneda, Luis Fernando Mayorga Ayala Funding agency: Ministerio de Ciencia e Innovación-MICINN Funding: 237500 Reference: PID2023-147387OB-I00 Duration: 01/09/2024 - 31/08/2027
IP: Fco Javier Santos Vicente Collaborators: Natalia Borruel Sainz, Ana Maria Gonzalez Castro Funding agency: Ministerio de Ciencia e Innovación-MICINN Funding: 218513 Reference: CPP2022-009979 Duration: 01/12/2023 - 30/11/2026
IP: - Collaborators: Santiago Pérez Hoyos, Joaquin Balsells Valls Funding agency: Ministerio de Ciencia e Innovación-MICINN Funding: 293321 Reference: CPP2022- 009592 Duration: 01/10/2023 - 30/09/2026
IP: - Collaborators: Raquel Ibañez Ferrer Funding agency: Cystic Fibrosis Foundation Funding: 300565.29 Reference: CFTR_CFF_RESEARCH GRANTS - FALL 2021 Duration: 01/05/2022 - 30/04/2024
PMID: 38178712 Journal: EUROPEAN PSYCHIATRY Year: 2024 Reference: Eur Psychiatry. 2024 Jan 5:1-31. doi: 10.1192/j.eurpsy.2023.2480. Impact factor: Publication type: Paper in international publication Authors: Amoretti, Silvia; Berge, Daniel; Bernardo, Miguel; Clougher, Derek; de la Serna, Elena; Fico, Giovanna; Forte, Maria Florencia; G Segura, Alex; Gasso, Patricia; Gonzalez-Pinto, Ana et al. DOI: 10.1192/j.eurpsy.2023.2480
PMID: 36900054 Journal: Diagnostics Year: 2023 Reference: Diagnostics (Basel). 2023 Feb 28;13(5):910. doi: 10.3390/diagnostics13050910. Impact factor: Publication type: Paper in international publication Authors: Azpiroz, Fernando; Bendezu, Alvaro; Malagelada, Carolina; Monclus, Eva; Navazo, Isabel; Orellana, Bernat et al. DOI: 10.3390/diagnostics13050910
PMID: 36919658 Journal: REVISTA ESPANOLA DE ENFERMEDADES DIGESTIVAS Year: 2023 Reference: Rev Esp Enferm Dig. 2023 Mar 15;115. doi: 10.17235/reed.2023.9568/2023. Impact factor: Publication type: Paper in international publication Authors: Albillos Martinez, Agustin; Bejarano Garcia, Ana; Casado Martin, Marta; Ceballos Santos, Daniel; Fernandez Vazquez, Inmaculada; Gomez Rodriguez, Rafael Angel; Iglesias Garcia, Julio; Malagelada Prats, Carolina; Malagelada Prats, Carolina; Orive Calzada, Aitor et al. DOI: 10.17235/reed.2023.9568/2023
PMID: 36936239 Journal: Frontiers in Medicine Year: 2023 Reference: Front Med (Lausanne). 2023 Mar 2;10:1089099. doi: 10.3389/fmed.2023.1089099. eCollection 2023. Impact factor: Publication type: Review in international publication Authors: Borruel, Natalia; Herrera-deGuise, Claudia; Lastiri, Ernesto; Lastiri, Ernesto; Serra-Ruiz, Xavier et al. DOI: 10.3389/fmed.2023.1089099
PMID: 36961016 Journal: NEUROGASTROENTEROLOGY AND MOTILITY Year: 2023 Reference: Neurogastroenterol Motil. 2023 Jun;35(6):e14566. doi: 10.1111/nmo.14566. Epub 2023 Mar 24. Impact factor: Publication type: Paper in international publication Authors: Andresen, Viola; Bangdiwala, Shrikant I; Benninga, Marc A; Bonaz, Bruno; Choi, Suck Chei; Corazziari, Enrico S; Fang, Xuicai; Fukudo, Shin; Hreinsson, Johann P; Kanazawa, Motoyori et al. DOI: 10.1111/nmo.14566
PMID: 34751672 Journal: AMERICAN JOURNAL OF GASTROENTEROLOGY Year: 2022 Reference: Am J Gastroenterol. 2022 Jan 1;117(1):147-157. doi: 10.14309/ajg.0000000000001541. Impact factor: 10.864 Publication type: Paper in international publication Authors: Eskazan, Tugce; Cremon, Cesare; Barbaro, Maria Raffaella; Salvi, Daniele; Cacciari, Giulia; Kagramanova, Anna; Bordin, Dmitry; Drug, Vasile; Miftode, Edgidia; Fusaroli, Pietro et al. DOI: 10.14309/ajg.0000000000001541
PMID: 34023479 Journal: Gastroenterologia y Hepatologia Year: 2022 Reference: Gastroenterol Hepatol. 2022 Feb;45(2):155-163. doi: 10.1016/j.gastrohep.2021.03.013. Epub 2021 May 21. Impact factor: 2.102 Publication type: Review in national publication Authors: Alcala-Gonzalez, L G; Serra, X; Barba, E et al. DOI: 10.1016/j.gastrohep.2021.03.013
PMID: 35126668 Journal: Therapeutic Advances in Gastroenterology Year: 2022 Reference: Therap Adv Gastroenterol. 2022 Feb 2;15:17562848221074204. doi: 10.1177/17562848221074204. eCollection 2022. Impact factor: 4.409 Publication type: Paper in international publication Authors: Racca, Francesca; Lucendo, Alfredo J; Santander, Cecilio; Savarino, Edoardo; Guagnozzi, Danila; Perez-Martinez, Isabel; Perello, Antonia; Guardiola-Arevalo, Antonio; Barrio, Jesus; Elena Betore-Glaria, Maria et al. DOI: 10.1177/17562848221074204
PMID: 35143108 Journal: NEUROGASTROENTEROLOGY AND MOTILITY Year: 2022 Reference: Neurogastroenterol Motil. 2022 Mar;34(3):e14333. doi: 10.1111/nmo.14333. Epub 2022 Feb 10. Impact factor: 3.598 Publication type: Review in international publication Authors: Serra, Jordi et al. DOI: 10.1111/nmo.14333
PMID: 35099124 Journal: United European Gastroenterology Journal Year: 2021 Reference: United European Gastroenterol J. 2021 Sep;9(7):883-884. doi: 10.1002/ueg2.12090. Epub 2021 Jul 14. Impact factor: 4.623 Publication type: Letter or abstract Authors: Pohl, Daniel, Mulak, A, Serra, J, Enck, P, Tack, J, Accarino, Anna, Barbara, Giovanni, Bor, Serhat, Coffin, Benoit, Corsetti, Maura et al. DOI: 10.1002/ueg2.12090
PMID: 34960094 Journal: Nutrients Year: 2021 Reference: Nutrients. 2021 Dec 18;13(12). pii: nu13124542. doi: 10.3390/nu13124542. Impact factor: 5.719 Publication type: Paper in international publication Authors: Neve, Boris Le, Martinez-De la Torre, Adrian, Tap, Julien, Ruiz, Adoracion Nieto, Derrien, Muriel, Cotillard, Aurelie, Faurie, Jean-Michel, Barba, Elizabeth, Mego, Marianela, Dornic, Quentin et al. DOI: 10.3390/nu13124542
PMID: 34944998 Journal: Cancers Year: 2021 Reference: Cancers (Basel). 2021 Dec 20;13(24). pii: cancers13246378. doi: 10.3390/cancers13246378. Impact factor: 6.639 Publication type: Paper in international publication Authors: Sanchez, Ariadna, Bujanda, Luis, Cuatrecasas, Miriam, Bofill, Alex, Alvarez-Urturi, Cristina, Hernandez, Goretti, Aguilera, Lara, Carballal, Sabela, Llach, Joan, Herrera-Pariente, Cristina et al. DOI: 10.3390/cancers13246378
PMID: 34938418 Journal: Computational and Structural Biotechnology Journal Year: 2021 Reference: Comput Struct Biotechnol J. 2021 Dec 2;19:6481-6489. doi: 10.1016/j.csbj.2021.11.037. eCollection 2021. Impact factor: 7.271 Publication type: Paper in international publication Authors: Serrano-Gomez, Gerard, Mayorga, Luis, Oyarzun, Inigo, Roca, Joaquim, Borruel, Natalia, Casellas, Francesc, Varela, Encarna, Pozuelo, Marta, Machiels, Kathleen, Guarner, Francisco et al. DOI: 10.1016/j.csbj.2021.11.037
PMID: 31912956 Journal: LIVER INTERNATIONAL Year: 2020 Reference: Liver Int. 2020 Mar;40(3):638-645. doi: 10.1111/liv.14375. Epub 2020 Jan 22. Impact factor: Publication type: Paper in international publication Authors: Aguilera-Castro, Lara; Albillos, Agustin; Alvarez-Fuente, Maria; Del Cerro, Maria Jesus; Garrido-Gomez, Elena; Garrido-Lestache Rodriguez-Monte, Elvira; Rodriguez de Santiago, Enrique; Tellez, Luis et al. DOI: 10.1111/liv.14375
PMID: 33130417 Journal: COMPUTERIZED MEDICAL IMAGING AND GRAPHICS Year: 2020 Reference: Comput Med Imaging Graph. 2020 Dec;86:101794. doi: 10.1016/j.compmedimag.2020.101794. Epub 2020 Oct 3. Impact factor: 3.75 Publication type: Paper in international publication Authors: Laiz, Pablo, Vitria, Jordi, Wenzek, Hagen, Malagelada, Carolina, Azpiroz, Fernando, Segui, Santi et al. DOI: 10.1016/j.compmedimag.2020.101794
PMID: 32968096 Journal: Scientific Reports Year: 2020 Reference: Sci Rep. 2020 Sep 23;10(1):15880. doi: 10.1038/s41598-020-69895-y. Impact factor: 3.998 Publication type: Letter or abstract Authors: Plancade, Sandra, Clark, Allison, Philippe, Catherine, Helbling, Jean-Christophe, Moisan, Marie-Pierre, Esquerre, Diane, Le Moyec, Laurence, Robert, Celine, Barrey, Eric, Mach, Nuria et al. DOI: 10.1038/s41598-020-69895-y
PMID: 31811952 Journal: Clinical Gastroenterology and Hepatology Year: 2020 Reference: Clin Gastroenterol Hepatol. 2020 Oct;18(11):2463-2470.e1. doi: 10.1016/j.cgh.2019.11.048. Epub 2019 Dec 4. Impact factor: 8.549 Publication type: Paper in international publication Authors: Huaman, Jose-Walter, Bendezu, Alvaro, Monrroy, Hugo, Samino, Sara, Accarino, Anna, Saperas, Esteban, Azpiroz, Fernando, Mego, Marianela et al. DOI: 10.1016/j.cgh.2019.11.048
PMID: 30707681 Journal: CLINICAL CHEMISTRY AND LABORATORY MEDICINE Year: 2019 Reference: Clin Chem Lab Med. 2019 Jun 26;57(7):1093-1101. doi: 10.1515/cclm-2018-1189. Impact factor: Publication type: Paper in international publication Authors: Aranda Nevado, M Cruz; Bayes-Genis, Antoni; Cediel, German; de Diego, Oriol; Ferrer, Marc; Garcia-Garcia, Cosme; Labata, Carlos; Lupon, Josep; Oliveras, Teresa; Revuelta Lopez, Elena et al. DOI: 10.1515/cclm-2018-1189
PMID: 30338693 Journal: REVISTA ESPANOLA DE ENFERMEDADES DIGESTIVAS Year: 2019 Reference: Rev Esp Enferm Dig. 2019 Jan;111(1):63-70. doi: 10.17235/reed.2018.5662/2018. Impact factor: 1.858 Publication type: Review in international publication Authors: Martinez, Javier, Aguilera, Lara, Albillos, Agustin et al. DOI: 10.17235/reed.2018.5662/2018
PMID: 30430456 Journal: Patient-Patient Centered Outcomes Research Year: 2019 Reference: Patient. 2019 Jun;12(3):307-317. doi: 10.1007/s40271-018-0345-1. Impact factor: 2.673 Publication type: Paper in international publication Authors: Orozco-Beltran, Domingo, de Toro, Javier, Galindo, Maria J, Marin-Jimenez, Ignacio, Casellas, Francesc, Fuster-RuizdeApodaca, Maria J, Garcia-Vivar, Maria L, Hormigo-Pozo, Antonio, Guilabert, Mercedes, Sanchez-Vega, Nuria et al. DOI: 10.1007/s40271-018-0345-1
PMID: 31628021 Journal: EBioMedicine Year: 2019 Reference: EBioMedicine. 2019 Oct;48:630-641. doi: 10.1016/j.ebiom.2019.10.002. Epub 2019 Oct 15. Impact factor: 6.68 Publication type: Paper in international publication Authors: Lleal, Marina, Sarrabayrouse, Guillaume, Willamil, Joseane, Santiago, Alba, Pozuelo, Marta, Manichanh, Chaysavanh et al. DOI: 10.1016/j.ebiom.2019.10.002
PMID: 29158075 Journal: Revista espanola de cardiologia (English ed.) Year: 2018 Reference: Rev Esp Cardiol (Engl Ed). 2018 Aug;71(8):638-642. doi: 10.1016/j.rec.2017.10.018. Epub 2017 Nov 20. Impact factor: Publication type: Paper in international publication Authors: Bayes-Genis, Antoni; Berastegui, Elisabet; Camara, Maria-Luisa; Ferrer, Marc; Garcia-Garcia, Cosme; Just, Maria-Soledad; Labata, Carlos; Oliveras, Teresa; Romero, Bernat; Rueda, Ferran et al. DOI: 10.1016/j.rec.2017.10.018
PMID: 29299814 Journal: JOURNAL OF GENERAL INTERNAL MEDICINE Year: 2018 Reference: J Gen Intern Med. 2018 May;33(5):668-677. doi: 10.1007/s11606-017-4244-2. Epub 2018 Jan 3. Impact factor: Publication type: Paper in international publication Authors: Bobadilla, Raudel; Liang, Yuanyuan; Rodriguez, Natalia; Simmonds, Maureen J; Turner, Barbara J; Yin, Zenong et al. DOI: 10.1007/s11606-017-4244-2
PMID: 29622456 Journal: INTERNATIONAL JOURNAL OF CARDIOLOGY Year: 2018 Reference: Int J Cardiol. 2018 Jun 1;260:7-10. doi: 10.1016/j.ijcard.2018.02.013. Impact factor: Publication type: Paper in international publication Authors: Bayes-Genis, Antoni; Carrillo, Xavier; Cediel, German; de Diego, Oriol; Ferrer, Marc; Garcia-Garcia, Cosme; Labata, Carlos; Oliveras, Teresa; Rueda, Ferran; Serra, Jordi et al. DOI: 10.1016/j.ijcard.2018.02.013
PMID: 30029826 Journal: European Journal of Obstetrics & Gynecology and Reproductive Biology Year: 2018 Reference: Eur J Obstet Gynecol Reprod Biol. 2018 Sep;228:331. doi: 10.1016/j.ejogrb.2018.06.012. Epub 2018 Jun 15. Impact factor: Publication type: Other (letters to the editor, abstracts, corrigendum, etc.) Authors: Chiantera, Antonio; Colacurci, Nicola; Scambia, Giovanni; Vicario, Maria; Viora, Elsa et al. DOI: 10.1016/j.ejogrb.2018.06.012
PMID: 28088505 Journal: JOURNAL OF PAIN Year: 2017 Reference: J Pain. 2017 Jun;18(6):628-636. doi: 10.1016/j.jpain.2016.12.019. Epub 2017 Jan 12. Impact factor: Publication type: Paper in international publication Authors: Liang, Yuanyuan; Potter, Jennifer S; Rochat, Andrea; Rodriguez, Natalia; Turner, Barbara J; Valerio, Melissa A; Winkler, Paula et al. DOI: 10.1016/j.jpain.2016.12.019
PMID: 29275366 Journal: Journal of the American Heart Association Year: 2017 Reference: J Am Heart Assoc. 2017 Dec 23;6(12):e007252. doi: 10.1161/JAHA.117.007252. Impact factor: Publication type: Paper in international publication Authors: Bayes-Genis, Antoni; Bodi, Vicent; Cediel, German; Ferrer, Marc; Garcia, Cosme; Labata, Carlos; Lupon, Josep; Nunez, Julio; Oliveras, Teresa; Rueda, Ferran et al. DOI: 10.1161/JAHA.117.007252
PMID: 27935079 Journal: MUSCLE & NERVE Year: 2017 Reference: Muscle Nerve. 2017 Sep;56(3):386-392. doi: 10.1002/mus.25507. Epub 2017 Apr 4. Impact factor: 2.713 Publication type: Paper in international publication Authors: Casal-Dominguez, Maria, Pinal-Fernandez, Iago, Mego, Marianela, Accarino, Anna, Jubany, Lluis, Azpiroz, Fernando, Selva-O'Callaghan, Albert et al. DOI: 10.1002/mus.25507
PMID: 27680592 Journal: JOURNAL OF CLINICAL GASTROENTEROLOGY Year: 2017 Reference: J Clin Gastroenterol. 2017 Aug;51(7):619-625. doi: 10.1097/MCG.0000000000000723. Impact factor: 3.163 Publication type: Paper in international publication Authors: Azpiroz, Fernando, Molne, Laura, Mendez, Sara, Nieto, Adoracion, Manichanh, Chaysavanh, Mego, Marianela, Accarino, Anna, Santos, Javier, Sailer, Manuela, Theis, Stephan et al. DOI: 10.1097/MCG.0000000000000723
PMID: 26670684 Journal: Year: 2016 Reference: Infect Dis (Lond). 2016;48(5):343-9. doi: 10.3109/23744235.2015.1122225. Epub 2015 Dec 15. Impact factor: Publication type: Paper in international publication Authors: Balandin, Barbara; Fernandez, Inmaculada; Galdos, Pedro; Garcia, Elena; Lobo, Beatriz; Martinez, Rocio; Orden, Beatriz; Ortega, Alfonso; Roman, Federico; Valdivia, Miguel et al. DOI: 10.3109/23744235.2015.1122225
PMID: 27138605 Journal: ADVANCES IN THERAPY Year: 2016 Reference: Adv Ther. 2016 Jun;33(6):877-93. doi: 10.1007/s12325-016-0336-3. Epub 2016 Apr 30. Impact factor: 2.503 Publication type: Review in international publication Authors: Malagelada, Juan R, Malagelada, Carolina et al. DOI: 10.1007/s12325-016-0336-3
PMID: 27147122 Journal: GASTROENTEROLOGY Year: 2016 Reference: Gastroenterology. 2016 May;150(6):1380-92. doi: 10.1053/j.gastro.2016.02.011. Impact factor: 18.187 Publication type: Review in international publication Authors: Stanghellini, Vincenzo, Chan, Francis K L, Hasler, William L, Malagelada, Juan R, Suzuki, Hidekazu, Tack, Jan, Talley, Nicholas J et al. DOI: 10.1053/j.gastro.2016.02.011
PMID: 26556786 Journal: NEUROGASTROENTEROLOGY AND MOTILITY Year: 2016 Reference: Neurogastroenterol Motil. 2016 Apr;28(4):463-86. doi: 10.1111/nmo.12717. Epub 2015 Nov 11. Impact factor: 3.587 Publication type: Paper in international publication Authors: Santos, J, Pigrau, M, Rodino-Janeiro, B K, Casado-Bedmar, M, Lobo, B, Vicario, M, Alonso-Cotoner, C et al. DOI: 10.1111/nmo.12717
PMID: 25853874 Journal: JOURNAL OF CLINICAL GASTROENTEROLOGY Year: 2015 Reference: J Clin Gastroenterol. 2015 May-Jun;49(5):370-8. doi: 10.1097/MCG.0000000000000307. Impact factor: 3.498 Publication type: Paper in international publication Authors: Malfertheiner, Peter, Salis, Graciela, Sharma, Prateek, Sifrim, Daniel, Vakil, Nimish, Le Mair, Anton, Lindberg, Greger, Kahrilas, Peter, Fried, Michael, De Looze, Danny et al. DOI: 10.1097/MCG.0000000000000307
PMID: 31040957 Journal: Clinical liver disease Year: 2015 Reference: Clin Liver Dis (Hoboken). 2015 May 7;5(4):86-90. doi: 10.1002/cld.454. eCollection 2015 Apr. Impact factor: 0 Publication type: Review in international publication Authors: Guarner, Francisco et al. DOI: 10.1002/cld.454
PMID: 26541659 Journal: REVISTA ESPANOLA DE ENFERMEDADES DIGESTIVAS Year: 2015 Reference: Rev Esp Enferm Dig. 2015 Nov;107(11):686-96. doi: 10.17235/reed.2015.3846/2015. Impact factor: 1.414 Publication type: Review in international publication Authors: Salvo Romero, Eloisa, Alonso Cotoner, Carmen, Pardo Camacho, Cristina, Casado Bedmar, Maite, Vicario, Maria et al. DOI: 10.17235/reed.2015.3846/2015
PMID: 25500424 Journal: GASTROENTEROLOGY Year: 2015 Reference: Gastroenterology. 2015 Apr;148(4):732-9. doi: 10.1053/j.gastro.2014.12.006. Epub 2014 Dec 11. Impact factor: 13.926 Publication type: Paper in international publication Authors: Barba, Elizabeth, Burri, Emanuel, Accarino, Anna, Cisternas, Daniel, Quiroga, Sergi, Monclus, Eva, Navazo, Isabel, Malagelada, Juan-R, Azpiroz, Fernando et al. DOI: 10.1053/j.gastro.2014.12.006
PMID: 25375680 Journal: IEEE J BIOMED HEALTH Year: 2014 Reference: IEEE J Biomed Health Inform. 2014 Nov;18(6):1831-8. doi: 10.1109/JBHI.2014.2304179. Impact factor: 0 Publication type: Paper in international publication Authors: Segui, Santi, Drozdzal, Michal, Zaytseva, Ekaterina, Malagelada, Carolina, Azpiroz, Fernando, Radeva, Petia, Vitria, Jordi et al. DOI: 10.1109/JBHI.2014.2304179
PMID: 25089542 Journal: EUR J GASTROEN HEPAT Year: 2014 Reference: Eur J Gastroenterol Hepatol. 2014 Oct;26(10):1167-75. doi: 10.1097/MEG.0000000000000089. Impact factor: 2.152 Publication type: Paper in international publication Authors: Dainese, Raffaella, Casellas, Francesc, Marine-Barjoan, Eugenia, Vivinus-Nebot, Mylene, Schneider, Stephane M, Hebuterne, Xavier, Piche, Thierry et al. DOI: 10.1097/MEG.0000000000000089
PMID: 25062884 Journal: PANCREATOLOGY Year: 2014 Reference: Pancreatology. 2014 Jul-Aug;14(4):316-8. doi: 10.1016/j.pan.2014.04.032. Epub 2014 May 9. Impact factor: 2.504 Publication type: Letter or abstract Authors: Vaquero, Eva C, Salcedo, Maria T, Cuatrecasas, Miriam, De Leon, Hannah, Merino, Xavier, Navarro, Salvador, Gines, Angels, Abu-Suboh, Monder, Balsells, Joaquim, Fernandez-Cruz, Laureano et al. DOI: 10.1016/j.pan.2014.04.032
PMID: 24997030 Journal: ADV EXP MED BIOL Year: 2014 Reference: Adv Exp Med Biol. 2014;817:73-113. doi: 10.1007/978-1-4939-0897-4_4. Impact factor: 2.012 Publication type: Review in national publication Authors: Alonso, Carmen, Vicario, Maria, Pigrau, Marc, Lobo, Beatriz, Santos, Javier et al. DOI: 10.1007/978-1-4939-0897-4_4
PMID: 23566414 Journal: Gastroenterologia y Hepatologia Year: 2013 Reference: Gastroenterol Hepatol. 2013 May;36(5):326-39. doi: 10.1016/j.gastrohep.2012.12.004. Epub 2013 Apr 6. Impact factor: 0.567 Publication type: Paper in national publication Authors: Gomez, Luis, Iglesias-Garcia, Julio, Garcia-Malpartida, Katherine, Guarner, Luisa, Larino-Noia, Jose, Lluis, Felix, Lopez, Antonio, Molero, Xavier, Moreno-Perez, Oscar, Navarro, Salvador et al. DOI: 10.1016/j.gastrohep.2012.12.004
PMID: 24641461 Journal: REVISTA ESPANOLA DE ENFERMEDADES DIGESTIVAS Year: 2013 Reference: Rev Esp Enferm Dig. 2013 Nov-Dec;105(10):626-8. doi: 10.4321/s1130-01082013001000009. Impact factor: 1.652 Publication type: Review in international publication Authors: Sihuay-Diburga, Denisse Joan, Accarino-Garaventa, Anna, Vilaseca-Montplet, Jaime, Azpiroz-Vidaur, Fernando et al. DOI: 10.4321/s1130-01082013001000009
PMID: 24917977 Journal: United European gastroenterology journal Year: 2013 Reference: United European Gastroenterol J. 2013 Oct;1(5):311-8. doi: 10.1177/2050640613502477. Impact factor: 0 Publication type: Review in international publication Authors: Dore, Joel, Simren, Magnus, Buttle, Lisa, Guarner, Francisco et al. DOI: 10.1177/2050640613502477
PMID: 23859454 Journal: REVISTA ESPANOLA DE ENFERMEDADES DIGESTIVAS Year: 2013 Reference: Rev Esp Enferm Dig. 2013 Apr;105(4):232-4. doi: 10.4321/s1130-01082013000400010. Impact factor: 1.652 Publication type: Paper in international publication Authors: Castillo-Cejas, Maria Dolores, de-Torres-Ramirez, Ines, Alonso-Cotoner, Carmen et al. DOI: 10.4321/s1130-01082013000400010
PMID: 22300112 Journal: REVISTA ESPANOLA DE ENFERMEDADES DIGESTIVAS Year: 2012 Reference: Rev Esp Enferm Dig. 2012 Feb;104(1):16-20. doi: 10.4321/s1130-01082012000100004. Impact factor: 1.548 Publication type: Paper in national publication Authors: Castells, Isabel, Borruel-Sainz, Natalia, Casellas-Jorda, Francesc, Torrejon-Herrera, Antonio et al. DOI: 10.4321/s1130-01082012000100004
PMID: 24218705 Journal: IEEE TRANSACTIONS ON INFORMATION TECHNOLOGY IN BIOMEDICINE Year: 2012 Reference: IEEE Trans Inf Technol Biomed. 2012 Nov;16(6):1341-52. Impact factor: 1.676 Publication type: Paper in international publication Authors: Segui, Santi, Drozdzal, Michal, Vilarino, Fernando, Malagelada, Carolina, Azpiroz, Fernando, Radeva, Petia, Vitria, Jordi et al. DOI: 10.1109/TITB.2012.2221472
PMID: 23588438 Journal: Nutricion Hospitalaria Year: 2012 Reference: Nutr Hosp. 2012 Nov-Dec;27(6):1908-15. doi: 10.3305/nh.2012.27.6.5992. Impact factor: 1.12 Publication type: Paper in international publication Authors: Lozano, M A, Moreno, Y, Paron, L, de la Cuerda, C, Breton, I, Camblor, M, Garcia-Hernandez, J, Guarner, F, Hernandez, M, Velasco, C et al. DOI: 10.3305/nh.2012.27.6.5992
PMID: 23075178 Journal: NEW ENGLAND JOURNAL OF MEDICINE Year: 2012 Reference: N Engl J Med. 2012 Oct 18;367(16):1519-28. doi: 10.1056/NEJMoa1203572. Impact factor: 53.298 Publication type: Paper in international publication Authors: Fishman, S, Sandborn, William J, Gasink, Christopher, Gao, Long-Long, Blank, Marion A, Johanns, Jewel, Guzzo, Cynthia, Sands, Bruce E, Hanauer, Stephen B, Targan, Stephan et al. DOI: 10.1056/NEJMoa1203572
PMID: 21951120 Journal: REVISTA ESPANOLA DE ENFERMEDADES DIGESTIVAS Year: 2011 Reference: Rev Esp Enferm Dig. 2011 Sep;103(9):492. doi: 10.4321/s1130-01082011000900010. Impact factor: 1.13 Publication type: Letter or abstract Authors: Accarino, Anna et al. DOI: 10.4321/s1130-01082011000900010
PMID: 20402734 Journal: Colorectal Disease Year: 2011 Reference: Colorectal Dis. 2011 Aug;13(8):926-9. doi: 10.1111/j.1463-1318.2010.02280.x. Epub 2010 Apr 5. Impact factor: 2.41 Publication type: Paper in international publication Authors: , , et al. DOI: 10.1111/j.1463-1318.2010.02280.x
PMID: 22129662 Journal: BRITISH JOURNAL OF NUTRITION Year: 2011 Reference: Br J Nutr. 2011 Nov;106 Suppl 2:S3-15. Impact factor: 3.072 Publication type: Paper in international publication Authors: Berta, Jean-Louis, Bub, Achim, de Vries, Jan, Guarner, Francisco, Hasselwander, Oliver, Hendriks, Henk, Jakel, Martin, Koletzko, Berthold V, Patterson, Chris C, Richelle, Myriam et al. DOI: 10.1017/S0007114511003606
PMID: 21914506 Journal: VALUE IN HEALTH Year: 2011 Reference: Value Health. 2011 Sep-Oct;14(6):859-61. Epub 2011 May 28. Impact factor: 2.342 Publication type: Paper in international publication Authors: Calvet, Xavier, Gallardo, Olga, Vergara, Mercedes, Montserrat, Antonia, Casellas, Francesc, Villoria, Albert, Suarez, David, Maudsley, Michael, Ricart, Elena et al. DOI: 10.1016/j.jval.2011.02.1179
PMID: 20524764 Journal: REVISTA ESPANOLA DE ENFERMEDADES DIGESTIVAS Year: 2010 Reference: Rev Esp Enferm Dig. 2010 May;102(5):337. doi: 10.4321/s1130-01082010000500010. Impact factor: 0.994 Publication type: Letter or abstract Authors: Accarino, A et al. DOI: 10.4321/s1130-01082010000500010
PMID: 19935081 Journal: JOURNAL OF CLINICAL GASTROENTEROLOGY Year: 2010 Reference: J Clin Gastroenterol. 2010 Jul;44(6):423-7. doi: 10.1097/MCG.0b013e3181c41d12. Impact factor: 2.207 Publication type: Paper in international publication Authors: Jorda, Francesc Casellas, Lopez Vivancos, Josefa et al. DOI: 10.1097/MCG.0b013e3181c41d12
PMID: 21637035 Journal: Gut microbes Year: 2010 Reference: Gut Microbes. 2010 Nov-Dec;1(6):436-9. doi: 10.4161/gmic.1.6.13610. Impact factor: 2.19 Publication type: Paper in international publication Authors: Rowland, Ian, Capurso, Lucio, Collins, Kevin, Cummings, John, Delzenne, Nathalie, Goulet, Olivier, Guarner, Francisco, Marteau, Philippe, Meier, Remy et al. DOI: 10.4161/gmic.1.6.13610
PMID: 21336423 Journal: Nutricion Hospitalaria Year: 2010 Reference: Nutr Hosp. 2010 Oct;25(5):700-704. Impact factor: 1.065 Publication type: Paper in national publication Authors: , , et al. DOI:
PMID: 21180543 Journal: Therapeutic advances in gastroenterology Year: 2009 Reference: Therap Adv Gastroenterol. 2009 Jul;2(4):201-3. doi: 10.1177/1756283X09335638. Impact factor: 0 Publication type: Editorail in international publication Authors: Whorwell, Peter J, Azpiroz, Fernando et al. DOI: 10.1177/1756283X09335638
PMID: 19388796 Journal: REVISTA ESPANOLA DE ENFERMEDADES DIGESTIVAS Year: 2009 Reference: Rev Esp Enferm Dig. 2009 Mar;101(3):163-71. doi: 10.4321/s1130-01082009000300002. Impact factor: 1.263 Publication type: Paper in national publication Authors: Huaman Rios, J W, Casellas Jorda, F, Malagelada Benapres, J R et al. DOI: 10.4321/s1130-01082009000300002
PMID: 19231678 Journal: Gastroenterol Hepatol Year: 2009 Reference: Gastroenterol Hepatol. 2009 Feb;32(2):77-82. doi: 10.1016/j.gastrohep.2008.09.015. Epub 2009 Feb 5. Impact factor: 0 Publication type: Paper in national publication Authors: Casellas Jorda, Francesc, Malagelada Benapres, Juan Ramon, Castillejo Badia, Neus, Borruel Sainz, Natalia, Torrejon Herrera, Antonio, Masachs Peracaula, Miquel, Castells Carner, Isabel et al. DOI: 10.1016/j.gastrohep.2008.09.015
PMID: 19404204 Journal: EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY Year: 2009 Reference: Eur J Gastroenterol Hepatol. 2009 Jul;21(7):809-15. Impact factor: 2.08 Publication type: Paper in international publication Authors: Vergara, Mercedes, Montserrat, Antonia, Casellas, Francesc, Maudsley, Michael, Gallardo, Olga, Ricart, Elena, Calvet, Xavier et al. DOI: 10.1097/MEG.0b013e32830f4c9e
PMID: 18537634 Journal: CURRENT MOLECULAR MEDICINE Year: 2008 Reference: Curr Mol Med. 2008 Jun;8(4):258-73. doi: 10.2174/156652408784533788. Impact factor: 4.624 Publication type: Editorail in international publication Authors: Santos, Javier, Alonso, Carmen, Vicario, Maria, Ramos, Laura, Lobo, Beatriz, Malagelada, J-Ramon et al. DOI: 10.2174/156652408784533788
PMID: 18691825 Journal: PSYCHONEUROENDOCRINOLOGY Year: 2008 Reference: Psychoneuroendocrinology. 2008 Oct;33(9):1248-56. doi: 10.1016/j.psyneuen.2008.07.002. Epub 2008 Aug 8. Impact factor: 4.422 Publication type: Paper in international publication Authors: Vicario, Maria, Alonso, Carmen, Perdue, Mary H, Guilarte, Mar, Yates, Derrick, Santos, Javier et al. DOI: 10.1016/j.psyneuen.2008.07.002
PMID: 18455999 Journal: GASTROENTEROLOGY Year: 2008 Reference: Gastroenterology. 2008 Jul;135(1):163-172.e1. doi: 10.1053/j.gastro.2008.03.036. Epub 2008 Mar 22. Impact factor: 11.673 Publication type: Paper in international publication Authors: Alonso, Carmen, Guilarte, Mar, Vicario, Maria, Ramos, Laura, Ramadan, Ziad, Antolin, Maria, Martinez, Cristina, Rezzi, Serge, Saperas, Esteban, Kochhar, Sunil et al. DOI: 10.1053/j.gastro.2008.03.036
PMID: 17005763 Journal: GUT Year: 2007 Reference: Gut. 2007 Feb;56(2):203-9. doi: 10.1136/gut.2006.100594. Epub 2006 Sep 27. Impact factor: 9.002 Publication type: Paper in international publication Authors: Guilarte, Mar, Santos, Javier, de Torres, Ines, Alonso, Carmen, Vicario, Maria, Ramos, Laura, Martinez, Cristina, Casellas, Francesc, Saperas, Esteban, Malagelada, Juan Ramon et al. DOI: 10.1136/gut.2006.100594
PMID: 16956793 Journal: CURRENT OPINION IN PHARMACOLOGY Year: 2006 Reference: Curr Opin Pharmacol. 2006 Dec;6(6):541-6. doi: 10.1016/j.coph.2006.08.001. Epub 2006 Sep 7. Impact factor: 5.366 Publication type: Editorail in international publication Authors: Alonso, Carmen, Malagelada, Juan Ramon, Vicario, Maria, Guilarte, Mar, Santos, Javier et al. DOI: 10.1016/j.coph.2006.08.001
PMID: 16206499 Journal: Clinical gastroenterology and hepatology : the official clinical practice journal of the American Ga Year: 2005 Reference: Clin Gastroenterol Hepatol. 2005 Jul;3(7):667-71. doi: 10.1016/s1542-3565(05)00363-0. Impact factor: 0 Publication type: Paper in international publication Authors: Malagelada, Juan Ramon, Santos, Javier, Guilarte, Mar, Alonso, Carmen, Ramos, Laura, Vilaseca, Jaime et al. DOI: 10.1016/s1542-3565(05)00363-0
PMID: 15764142 Journal: SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY Year: 2005 Reference: Scand J Gastroenterol. 2005 Feb;40(2):129-40. doi: 10.1080/00365520410009410. Impact factor: 1.824 Publication type: Editorail in international publication Authors: Malagelada, J R, Alonso, Carmen, Guilarte, Mar, Santos, Javier et al. DOI: 10.1080/00365520410009410
PhD student: Merce Albert Bayo Director/s: Fernando Azpiroz Vidaur University: Universitat Autònoma de Barcelona Year: 2023
PhD student: Claudia Barber Caselles Director/s: Fernando Azpiroz Vidaur University: Universitat Autònoma de Barcelona Year: 2023
PhD student: Zixuan Xie Director/s: Chaysavanh Manichanh , Victor Manuel Vargas Blasco University: Universitat Autònoma de Barcelona Year: 2023
PhD student: Luis Gerardo Alcala Gonzalez, Luis Gerardo Alcala Gonzalez Director/s: Fernando Azpiroz Vidaur, Carolina Malagelada Prats University: Year: 2022
PhD student: Luis Gerardo Alcala Gonzalez, Luis Gerardo Alcala Gonzalez Director/s: Carolina Malagelada Prats, Fernando Azpiroz Vidaur University: Year: 2022
PhD student: Francisca Yañez Araya Director/s: Chaysavanh Manichanh University: Universidad Autònoma de Barcelona Year: 2022
PhD student: Claudia Maria Herrera de Guise Director/s: Francisco Guarner Aguilar University: Universidad Autònoma de Barcelona Year: 2021
PhD student: Monder Abu-Suboh Abadia Director/s: Manuel Armengol Carrasco University: Universidad Autònoma de Barcelona Year: 2020
PhD student: Xavier Martínez Serrano Director/s: Chaysavanh Manichanh University: Universidad Autònoma de Barcelona Year: 2020
PhD student: Marina Fortea Guillamon Director/s: Fernando Azpiroz Vidaur, Maria Vicario Perez University: Universidad Autònoma de Barcelona Year: 2020
PhD student: José Wálter Huamán Ríos Director/s: Ana María Accarino Garaventa, Fernando Azpiroz Vidaur, Ana María Accarino Garaventa University: Universidad Autònoma de Barcelona Year: 2020
PhD student: Marta Pozuelo Del Rio Director/s: Chaysavanh Manichanh University: Universidad Autònoma de Barcelona Year: 2019
PhD student: Eloisa Salvo Romero Director/s: Fco Javier Santos Vicente, Maria Vicario Perez University: Universidad Autònoma de Barcelona Year: 2018
PhD student: Alba Santiago Badenas Director/s: Chaysavanh Manichanh University: Universidad Autònoma de Barcelona Year: 2018
PhD student: Marc Pigrau Pastor Director/s: Fco Javier Santos Vicente, Carmen Alonso Cotoner, Maria Vicario Perez University: Universidad Autònoma de Barcelona Year: 2018
PhD student: Rogger Alvaro Bendezú García Director/s: Fernando Azpiroz Vidaur University: Universidad Autònoma de Barcelona Year: 2016
PhD student: Elizabeth Barba Orozco Director/s: Elizabeth Barba Orozco, Ana María Accarino Garaventa, Fernando Azpiroz Vidaur, Ana María Accarino Garaventa University: Universidad Autònoma de Barcelona Year: 2015
PhD student: Marianela Mego Silva Director/s: Fernando Azpiroz Vidaur University: Universidad Autònoma de Barcelona Year: 2015
PhD student: Beatriz Lobo Alvarez Director/s: Fco Javier Santos Vicente, Maria Vicario Perez University: Universidad Autònoma de Barcelona Year: 2013
PhD student: Carolina Malagelada Prats, Carolina Malagelada Prats Director/s: Fernando Azpiroz Vidaur University: Universidad Autònoma de Barcelona Year: 2010
PhD student: Carmen Alonso Cotoner Director/s: Fco Javier Santos Vicente, Joan Ramón Malagelada Benaprés, Joan Ramón Malagelada Benaprés University: Universidad Autònoma de Barcelona Year: 2010
PhD student: Natalia Borruel Sainz, Natalia Borruel Sainz Director/s: University: Universidad Autònoma de Barcelona Year: 2005
Among the genes described, there are some related to digestive system functions, which reinforces the biological entity of irritable bowel syndrome as a digestive disease.
The international study, in which Vall d'Hebron participated, monitored patients who were hospitalized for COVID-19 for 12 months and compared their gastrointestinal symptoms with another group of patients diagnosed with other medical pathologies.
Els estudis avançaran en els camps de les malalties digestives, el VIH, la fatiga crònica, les patologies cardíaques, l’hepatitis, la diabetis i l’oftalmologia.
