About the VHIR
Here at the Vall d'Hebron Research Institute (VHIR) we promote biomedical research, innovation and teaching. Over 1,800 people are seeking to understand diseases today so the treatment can be improved tomorrow.
Research
We are working to understand diseases, to find out how they operate and to create better treatments for patients. Get to know about our groups and their lines of research.
People
People are the centre of the Vall d'Hebron Research Institute (VHIR). This is why we are bound by the principles of freedom of research, gender equality and professional attitudes that HRS4R promotes.
Clinical trials
Our work is not just basic or translational; we are leaders in clinical research. Enter and find about the clinical trials we are conducting and why we are a world reference in this field.
Progress
Our aim is to make the research carried out at the Vall d’Hebron Research Institute (VHIR) a driving force for transformation. How? By identifying new channels and solutions for the promotion of people's health and well-being.
Core facilities
We offer specialist support for researchers, internal and external alike, ranging from specific services to preparing complete projects. All this, from a perspective of quality and speed of response.
News
We offer you a gateway for staying up to date on everything going on at the Vall d’Hebron Research Institute (VHIR), from the latest news to future solidarity activities and initiatives that we are organising.
The group of Physiology and Pathophysiology of the Digestive Tract focuses its research activity on the functioning of the digestive tract as a whole, including the functions of secretion, motility, absorption and barrier both in healthy individuals and in the presence of disease. The application of knowledge to clinical practice is a priority for the group.
Research in digestive motility encompasses disorders of visceral sensitivity, the brain-gut axis and intestinal allergy. Research on inflammation also includes the pancreas.
We have also launched a cross-sectional research program that focuses on the role of the gut microbiota in inflammation and gut function.
The focus of our research is to study the series of pathophysiologic events leading to acute and chronic pancreatitis and, eventually, pancreatic cancer. We aim to take advantage of knowledge gained at our basic research program to design therapeutic strategies intended to prevent or ameliorate human pancreatic disorders. In rodent models of acute and chronic pancreatitis we examine pancreatic regeneration, fibrogenesis, acino-ductal trandiferentiation, stellate cell activation, epithelial-to-mesenchymal transition and cancer development. In human pancreatitis we investigate environmental and genetic determinants (with special focus at CFTR dysfunction) and new treatment modalities for acute and chronic pancreatitis.
IP: Francesc Xavier Molero Richard
Mucosal surfaces of the gastrointestinal, bronchopulmonary, and genitourinary tracts constitute the most prominent site of interaction between the host and the external habitat and a real hub where microbes and the host bi-directionally communicate through mechanisms that engage the activation of the immune and nervous systems. Barrier mechanisms have evolved early in evolution, and consist of a number of anatomical and functional elements distributed across the tissue layers, which tightly interact to maintain homeostasis. The mucosal immune system develops fundamental defensive and homeostatic duties at mucosal sites through activation of innate and adaptive immunity and the development of tolerogenic responses against harmless antigens. Immune responses also include the resolution of inflammation to avoid tissue damage after antigen penetration. However, uncontrolled immune activity is associated with mucosal barrier failure and organ dysfunction, which characterize most organic and functional disorders. The major goal of the Translational Mucosal Immunology lab is to further identify the role of specific immune cells (mast cells, eosinophils and B cells) as major players in the control of mucosal barrier mechanisms in health and disease. Our approach to translational research in digestive diseases involves the development of preclinical and clinical studies aimed at identifying biomarkers of gastrointestinal dysfunction and gut health.
IP: Maria Vicario Perez
IP: Chaysavanh Manichanh Collaborators: Laura Campderros Traver, Judit Álvarez González Funding agency: Instituto de Salud Carlos III Funding: 95000 Reference: CD22/00177 Duration: 01/03/2023 - 28/02/2025
IP: Fernando Azpiroz Vidaur Collaborators: - Funding agency: Ministerio de Ciencia e Innovación-MICINN Funding: 108900 Reference: PID2021-122295OB-I00 Duration: 01/09/2022 - 01/09/2026
IP: José García Arumí Collaborators: María Antolín Mate, Anna Duarri Piqué, Helena Isla Magrané, Claudia Garcia-Arumí Fusté, Miguel Angel Zapata Victori, Laura Natalia Distefano, Randa Falah Funding agency: Instituto de Salud Carlos III Funding: 123420 Reference: PI22/01747 Duration: 01/01/2023 - 31/12/2025
IP: Jorge Serra Pueyo Collaborators: Ariadna Aguilar Cayuelas, Anna Beneria González, Claudia Barber Caselles Funding agency: Instituto de Salud Carlos III Funding: 135520 Reference: PI22/00618 Duration: 01/01/2023 - 31/12/2025
PMID: 37010843 Journal: NEUROGASTROENTEROLOGY AND MOTILITY Year: 2023 Reference: Neurogastroenterol Motil. 2023 Jun;35(6):e14582. doi: 10.1111/nmo.14582. Epub 2023 Apr 3. Impact factor: Publication type: Paper in international publication Authors: Alonso-Cotoner, Carmen; Aso, Maria C; Bangdiwala, Shrikant I; Bujanda, Luis; Flores-Arriaga, Joel; Izagirre, Arantzazu; Lanas, Angel; Lobo, Beatriz; Palsson, Olafur S; Sanchez-Pla, Alex et al. DOI: 10.1111/nmo.14582
PMID: 37018412 Journal: NEUROGASTROENTEROLOGY AND MOTILITY Year: 2023 Reference: Neurogastroenterol Motil. 2023 Jun;35(6):e14583. doi: 10.1111/nmo.14583. Epub 2023 Apr 5. Impact factor: Publication type: Paper in international publication Authors: Adibi, Payman; Andresen, Viola; Archampong, Timothy; Bangdiwala, Shrikant I; Benninga, Marc A; Bonaz, Bruno; Bor, Serhat; Buyruk, Murat; Choi, Suck Chei; Corazziari, Enrico S et al. DOI: 10.1111/nmo.14583
PMID: 37170542 Journal: REVISTA ESPANOLA DE ENFERMEDADES DIGESTIVAS Year: 2023 Reference: Rev Esp Enferm Dig. 2023 May 12. doi: 10.17235/reed.2023.9436/2022. Impact factor: Publication type: Paper in international publication Authors: Borruel, Natalia; Borruel, Natalia; Casellas, Francesc; Casellas, Francesc; Cespedes Martinez, Elena; Herrera-De Guise, Claudia; Herrera-De Guise, Claudia; Mayorga, Luis; Robles Alonso, Virginia; Robles Alonso, Virginia et al. DOI: 10.17235/reed.2023.9436/2022
PMID: 37242129 Journal: Nutrients Year: 2023 Reference: Nutrients. 2023 May 9;15(10):2247. doi: 10.3390/nu15102247. Impact factor: Publication type: Paper in international publication Authors: Azpiroz, Fernando; Livovsky, Dan M; Nieto, Adoracion et al. DOI: 10.3390/nu15102247
PMID: 35161583 Journal: SENSORS Year: 2022 Reference: Sensors (Basel). 2022 Jan 22;22(3). pii: s22030838. doi: 10.3390/s22030838. Impact factor: 3.576 Publication type: Paper in international publication Authors: Freire, Rafael; Mego, Marianela; Oliveira, Luciana Fontes; Mas, Silvia; Azpiroz, Fernando; Marco, Santiago; Pardo, Antonio et al. DOI: 10.3390/s22030838
PMID: 35163449 Journal: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES Year: 2022 Reference: Int J Mol Sci. 2022 Jan 28;23(3). pii: ijms23031527. doi: 10.3390/ijms23031527. Impact factor: 5.924 Publication type: Paper in international publication Authors: Notararigo, Sara; Varela, Encarnacion; Otal, Anna; Antolin, Maria; Guarner, Francisco; Lopez, Paloma et al. DOI: 10.3390/ijms23031527
PMID: 35764931 Journal: BMC GASTROENTEROLOGY Year: 2022 Reference: BMC Gastroenterol. 2022 Jun 28;22(1):320. doi: 10.1186/s12876-022-02392-w. Impact factor: 3.067 Publication type: Paper in international publication Authors: Batista, Lissette; Robles, Virginia; Manichanh, Chaysavanh; Ruiz, Laura; Pinsach, Ferran; Guarner, Francisco; Fernandez-Banares, Fernando; Guagnozzi, Danila et al. DOI: 10.1186/s12876-022-02392-w
PMID: 35838300 Journal: CURRENT OPINION IN CLINICAL NUTRITION AND METABOLI Year: 2022 Reference: Curr Opin Clin Nutr Metab Care. 2022 Jul 16. pii: 00075197-990000000-00020. doi: 10.1097/MCO.0000000000000856. Impact factor: 4.294 Publication type: Paper in international publication Authors: Aguilar, Ariadna, Serra, Jordi, Malagelada, Carolina et al. DOI: 10.1097/MCO.0000000000000856
PMID: 34778332 Journal: Frontiers in Nutrition Year: 2021 Reference: Front Nutr. 2021 Oct 28;8:718093. doi: 10.3389/fnut.2021.718093. eCollection 2021. Impact factor: 6.576 Publication type: Review in international publication Authors: Fortea, Marina, Albert-Bayo, Merce, Abril-Gil, Mar, Ganda Mall, John-Peter, Serra-Ruiz, Xavier, Henao-Paez, Alejandro, Exposito, Elba, Gonzalez-Castro, Ana Maria, Guagnozzi, Danila, Lobo, Beatriz et al. DOI: 10.3389/fnut.2021.718093
PMID: 34586707 Journal: NEUROGASTROENTEROLOGY AND MOTILITY Year: 2021 Reference: Neurogastroenterol Motil. 2021 Sep;33(9):e14238. doi: 10.1111/nmo.14238. Impact factor: 3.598 Publication type: Paper in international publication Authors: Wauters, Lucas, Dickman, Ram, Drug, Vasile, Mulak, Agata, Serra, Jordi, Smet, Annemieke, Stengel, Andreas, Storonova, Olga, Storr, Martin, Tornblom, Hans et al. DOI: 10.1111/nmo.14238
PMID: 34578856 Journal: Nutrients Year: 2021 Reference: Nutrients. 2021 Aug 27;13(9). pii: nu13092978. doi: 10.3390/nu13092978. Impact factor: 5.719 Publication type: Paper in international publication Authors: Serrano-Gomez, Gerard, Manichanh, Chaysavanh, Oyarzun, Inigo, Xie, Zixuan, Oliero, Manon, Soler, Zaida, Yanez, Francisca et al. DOI: 10.3390/nu13092978
PMID: 34444797 Journal: Nutrients Year: 2021 Reference: Nutrients. 2021 Jul 30;13(8). pii: nu13082638. doi: 10.3390/nu13082638. Impact factor: 5.719 Publication type: Paper in international publication Authors: Barber, Claudia, Mego, Marianela, Sabater, Carlos, Vallejo, Fernando, Bendezu, Rogger Alvaro, Masihy, Marcela, Guarner, Francisco, Espin, Juan Carlos, Margolles, Abelardo, Azpiroz, Fernando et al. DOI: 10.3390/nu13082638
PMID: 32856764 Journal: NEUROGASTROENTEROLOGY AND MOTILITY Year: 2020 Reference: Neurogastroenterol Motil. 2020 Sep;32(9):e13981. doi: 10.1111/nmo.13981. Impact factor: 2.946 Publication type: Letter or abstract Authors: Whorwell, Peter, Serra, Jordi, Pohl, Daniel, Azpiroz, Fernando, Chiarioni, Giuseppe, Ducrotte, Philippe, Gourcerol, Guillaume, Hungin, Amrit Pali S, Layer, Peter, Mendive, Juan-Manuel et al. DOI: 10.1111/nmo.13981
PMID: 32804838 Journal: EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY Year: 2020 Reference: Eur J Gastroenterol Hepatol. 2020 Dec;32(12):1514-1522. doi: 10.1097/MEG.0000000000001885. Impact factor: 2.251 Publication type: Paper in international publication Authors: Casellas, Francesc, Guinard Vicens, Daniel, Garcia-Lopez, Santiago, Gonzalez-Lama, Yago, Arguelles-Arias, Federico, Barreiro-de Acosta, Manuel, Marin Sanchez, Laura, Mendive, Juan Manuel, Saldana, Roberto, Cabez, Ana et al. DOI: 10.1097/MEG.0000000000001885
PMID: 32740086 Journal: AMERICAN JOURNAL OF GASTROENTEROLOGY Year: 2020 Reference: Am J Gastroenterol. 2020 Dec;115(12):2047-2059. doi: 10.14309/ajg.0000000000000789. Impact factor: 10.171 Publication type: Paper in international publication Authors: Guilarte, Mar, Vicario, Maria, Martinez, Cristina, de Torres, Ines, Lobo, Beatriz, Pigrau, Marc, Gonzalez-Castro, Ana, Rodino-Janeiro, Bruno K, Salvo-Romero, Eloisa, Fortea, Marina et al. DOI: 10.14309/ajg.0000000000000789
PMID: 32722760 Journal: Journal of Crohns & Colitis Year: 2020 Reference: J Crohns Colitis. 2020 Jul 29. pii: 5877457. doi: 10.1093/ecco-jcc/jjaa159. Impact factor: 8.658 Publication type: Paper in international publication Authors: Ghosh, Subrata, Sensky, Tom, Casellas, Francesc, Rioux, Louis-Charles, Ahmad, Tariq, Marquez, Juan R, Vanasek, Tomas, Gubonina, Irina, Sezgin, Orhan, Ardizzone, Sandro et al. DOI: 10.1093/ecco-jcc/jjaa159
PMID: 30527539 Journal: CLINICAL NUTRITION Year: 2019 Reference: Clin Nutr. 2019 Oct;38(5):2304-2310. doi: 10.1016/j.clnu.2018.10.004. Epub 2018 Oct 9. Impact factor: 6.402 Publication type: Paper in international publication Authors: Levenez, Florence, Cournede, Nicole, Dore, Joel, Melchior, Jean-Claude, Pascal, Victoria, Schoenenberger, Andreu, Manichanh, Chaysavanh, Hanachi, Mouna et al. DOI: 10.1016/j.clnu.2018.10.004
PMID: 31545923 Journal: AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY Year: 2019 Reference: Am J Physiol Gastrointest Liver Physiol. 2019 Dec 1;317(6):G793-G801. doi: 10.1152/ajpgi.00199.2019. Epub 2019 Sep 23. Impact factor: 3.729 Publication type: Paper in international publication Authors: Boschetti, Elisa, Malagelada, Carolina, Accarino, Anna, Malagelada, Juan R, Cogliandro, Rosanna F, Gori, Alessandra, Bonora, Elena, Giancola, Fiorella, Bianco, Francesca, Tugnoli, Vitaliano et al. DOI: 10.1152/ajpgi.00199.2019
PMID: 31507575 Journal: Frontiers in Microbiology Year: 2019 Reference: Front Microbiol. 2019 Aug 27;10:1973. doi: 10.3389/fmicb.2019.01973. eCollection 2019. Impact factor: 4.259 Publication type: Editorail in international publication Authors: Langella, Philippe, Guarner, Francisco, Martin, Rebeca et al. DOI: 10.3389/fmicb.2019.01973
PMID: 31402544 Journal: NEUROGASTROENTEROLOGY AND MOTILITY Year: 2019 Reference: Neurogastroenterol Motil. 2019 Dec;31(12):e13703. doi: 10.1111/nmo.13703. Epub 2019 Aug 11. Impact factor: 3.803 Publication type: Paper in international publication Authors: Monclus, Eva, Navazo, Isabel, Guarner, Francisco, Margolles, Abelardo, Azpiroz, Fernando, Accarino, Anna, Burri, Emanuel, Sanchez, Borja, Barba, Elizabeth et al. DOI: 10.1111/nmo.13703
PMID: 29960663 Journal: AMERICAN JOURNAL OF CARDIOLOGY Year: 2018 Reference: Am J Cardiol. 2018 Aug 15;122(4):529-536. doi: 10.1016/j.amjcard.2018.04.054. Epub 2018 Jun 27. Impact factor: Publication type: Paper in international publication Authors: Bayes-Genis, Antoni; Carrillo, Xavier; Faixedas, Maria Teresa; Fernandez-Nofrerias, Eduard; Ferrer, Marc; Garcia-Garcia, Cosme; Jimenez, Javier; Labata, Carlos; Lupon, Josep; Mauri, Josepa et al. DOI: 10.1016/j.amjcard.2018.04.054
PMID: 28941004 Journal: NEUROGASTROENTEROLOGY AND MOTILITY Year: 2018 Reference: Neurogastroenterol Motil. 2018 Mar;30(3). doi: 10.1111/nmo.13219. Epub 2017 Sep 22. Impact factor: 3.617 Publication type: Paper in international publication Authors: Malagelada, C, Karunaratne, T B, Accarino, A, Cogliandro, R F, Landolfi, S, Gori, A, Boschetti, E, Malagelada, J R, Stanghellini, V, Azpiroz, F et al. DOI: 10.1111/nmo.13219
PMID: 28460821 Journal: ANALES DE PEDIATRIA Year: 2018 Reference: An Pediatr (Barc). 2018 Feb;88(2):100-105. doi: 10.1016/j.anpedi.2017.03.011. Epub 2017 Apr 29. Impact factor: 1.14 Publication type: Paper in national publication Authors: Segarra Canton, Oscar, Azpiroz Vidaur, Fernando, Gimenez Casado, Aida, Lopez Linan, Maria Jose, Barba Orozco, Elisabeth, Accarino Garaventa, Anna, Alvarez Beltran, Marina et al. DOI: 10.1016/j.anpedi.2017.03.011
PMID: 30525861 Journal: Nutricion Hospitalaria Year: 2018 Reference: Nutr Hosp. 2018 Dec 3;35(6):1450-1466. Impact factor: 0.747 Publication type: Paper in international publication Authors: Casellas, Francesc, Burgos, Rosa, Marcos, Ascension, Santos, Javier, Ciriza-de-Los-Rios, Constanza, Garcia-Manzanares, Alvaro, Polanco, Isabel, Puy-Portillo, Maria, Villarino, Antonio, Lema-Marques, Beatriz et al. DOI:
PMID: 29099093 Journal: Nature Reviews Disease Primers Year: 2017 Reference: Nat Rev Dis Primers. 2017 Nov 3;3:17081. doi: 10.1038/nrdp.2017.81. Impact factor: 6.389 Publication type: Review in international publication Authors: Azpiroz, Fernando, Enck, Paul, Feinle-Bisset, Christine, Holtmann, Gerald, Lackner, Jeffrey M, Ronkainen, Jukka, Schemann, Michael, Stengel, Andreas, Tack, Jan, Zipfel, Stephan et al. DOI: 10.1038/nrdp.2017.81
PMID: 29026591 Journal: United European Gastroenterology Journal Year: 2017 Reference: United European Gastroenterol J. 2017 Oct;5(6):773-788. doi: 10.1177/2050640617731968. Epub 2017 Sep 28. Impact factor: 3.673 Publication type: Review in national publication Authors: Moayyedi, Paul, Mearin, Fermin, Azpiroz, Fernando, Andresen, Viola, Barbara, Giovanni, Corsetti, Maura, Emmanuel, Anton, Hungin, A Pali S, Layer, Peter, Stanghellini, Vincenzo et al. DOI: 10.1177/2050640617731968
PMID: 29026603 Journal: United European Gastroenterology Journal Year: 2017 Reference: United European Gastroenterol J. 2017 Oct;5(6):887-897. doi: 10.1177/2050640617691690. Epub 2017 Jan 29. Impact factor: 3.673 Publication type: Paper in international publication Authors: Azpiroz, Fernando, Santos, Javier, Vicario, Maria, Guagnozzi, Danila, Pardo-Camacho, Cristina, Salvo-Romero, Eloisa, Lobo, Beatriz, Ramos, Laura, Martinez, Cristina, Guilarte, Mar et al. DOI: 10.1177/2050640617691690
PMID: 28967887 Journal: NATURE BIOTECHNOLOGY Year: 2017 Reference: Nat Biotechnol. 2017 Nov;35(11):1069-1076. doi: 10.1038/nbt.3960. Epub 2017 Oct 2. Impact factor: 41.667 Publication type: Paper in international publication Authors: Costea, Paul I, Zeller, Georg, Sunagawa, Shinichi, Pelletier, Eric, Alberti, Adriana, Levenez, Florence, Tramontano, Melanie, Driessen, Marja, Hercog, Rajna, Jung, Ferris-Elias et al. DOI: 10.1038/nbt.3960
PMID: 26481311 Journal: FASEB JOURNAL Year: 2016 Reference: FASEB J. 2016 Feb;30(2):544-54. doi: 10.1096/fj.15-272773. Epub 2015 Oct 19. Impact factor: 5.043 Publication type: Paper in international publication Authors: Fernandez-Calotti, Paula, Casulleras, Olga, Antolin, Maria, Guarner, Francisco, Pastor-Anglada, Marcal et al. DOI: 10.1096/fj.15-272773
PMID: 25921480 Journal: Journal of health psychology Year: 2016 Reference: J Health Psychol. 2016 Nov;21(11):2590-2599. doi: 10.1177/1359105315581069. Epub 2016 Jul 9. Impact factor: Publication type: Letter or abstract Authors: Azpiroz, Fernando, Parramon, Gemma, Santamarina-Perez, Pilar, Accarino, Anna, Rodriguez-Urrutia, Amanda, Eiroa-Orosa, Francisco Jose et al. DOI: 10.1177/1359105315581069
PMID: 27057682 Journal: INFLAMMATORY BOWEL DISEASES Year: 2016 Reference: Inflamm Bowel Dis. 2016 Jun;22(6):1450-5. doi: 10.1097/MIB.0000000000000768. Impact factor: 4.358 Publication type: Paper in international publication Authors: Herrera-deGuise, Claudia, Casellas, Francesc, Robles, Virginia, Navarro, Ester, Borruel, Natalia et al. DOI: 10.1097/MIB.0000000000000768
PMID: 27271780 Journal: NEUROGASTROENTEROLOGY AND MOTILITY Year: 2016 Reference: Neurogastroenterol Motil. 2016 Dec;28(12):1806-1814. doi: 10.1111/nmo.12879. Epub 2016 Jun 7. Impact factor: 3.31 Publication type: Paper in international publication Authors: Azpiroz, F, Santos, J, Malagelada, C, Barba, I, Accarino, A, Molne, L, Mendez, S, Campos, E, Gonzalez, A, Alonso-Cotoner, C et al. DOI: 10.1111/nmo.12879
PMID: 25014236 Journal: JOURNAL OF CLINICAL GASTROENTEROLOGY Year: 2015 Reference: J Clin Gastroenterol. 2015 Aug;49(7):e64-70. doi: 10.1097/MCG.0000000000000178. Impact factor: 3.186 Publication type: Paper in international publication Authors: Azpiroz, Fernando, Guyonnet, Denis, Donazzolo, Yves, Gendre, David, Tanguy, Jerome, Guarner, Francisco et al. DOI: 10.1097/MCG.0000000000000178
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PMID: 25160690 Journal: JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY Year: 2015 Reference: J Gastroenterol Hepatol. 2015 Jan;30(1):92-8. doi: 10.1111/jgh.12712. Impact factor: 3.504 Publication type: Paper in international publication Authors: Cossio-Gil, Yolima, Martinez-Gomez, Xavier, Campins-Marti, Magda, Rodrigo-Pendas, Jose Angel, Borruel-Sainz, Natalia, Rodriguez-Frias, Francisco, Casellas-Jorda, Francesc et al. DOI: 10.1111/jgh.12712
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PMID: 24801842 Journal: CHIMIA Year: 2014 Reference: Chimia (Aarau). 2014;68(3):129-34. doi: 10.2533/chimia.2014.129. Impact factor: 1.091 Publication type: Clinical Trials Authors: Nagy, Kornel, Lobo, Beatriz, Courtet-Compondu, Marie-Claude, Braga-Lagache, Sophie, Ramos, Laura, Puig-Divi, Valenti, Azpiroz, Fernando, Malagelada, Juan Ramon, Beaumont, Maurice, Moulin, Julie et al. DOI: 10.2533/chimia.2014.129
PMID: 25201043 Journal: NAT REV GASTRO HEPAT Year: 2014 Reference: Nat Rev Gastroenterol Hepatol. 2014 Nov;11(11):647-9. doi: 10.1038/nrgastro.2014.156. Epub 2014 Sep 9. Impact factor: 10.807 Publication type: Paper in international publication Authors: Guarner, Francisco et al. DOI: 10.1038/nrgastro.2014.156
PMID: 25022563 Journal: Endocrine, Metabolic & Immune Disorders - Drug Targets Year: 2014 Reference: Endocr Metab Immune Disord Drug Targets. 2014;14(4):290-9. Impact factor: 0 Publication type: Review in international publication Authors: Panda, Suchita, Guarner, Francisco, Manichanh, Chaysavanh et al. DOI: 10.2174/1871530314666140714120744
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PMID: 24141494 Journal: NATURE METHODS Year: 2013 Reference: Nat Methods. 2013 Dec;10(12):1196-9. doi: 10.1038/nmeth.2693. Epub 2013 Oct 20. Impact factor: 23.565 Publication type: Paper in international publication Authors: Mende, Daniel R, Zeller, Georg, Izquierdo-Carrasco, Fernando, Berger, Simon A, Kultima, Jens Roat, Coelho, Luis Pedro, Arumugam, Manimozhiyan, Tap, Julien, Nielsen, Henrik Bjorn, Sunagawa, Shinichi et al. DOI: 10.1038/nmeth.2693
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PMID: 22966490 Journal: Autophagy Year: 2012 Reference: Autophagy. 2012 Apr;8(4):445-544. Impact factor: 7.453 Publication type: Review in international publication Authors: Bai, Xue-Yuan, Albin, Roger L, Alegre-Abarrategui, Javier, Aleo, Maria Francesca, Alirezaei, Mehrdad, Almasan, Alexandru, Almonte-Becerril, Maylin, Amano, Atsuo, Amaravadi, Ravi, Amarnath, Shoba et al. DOI:
PMID: 22907164 Journal: Nature Reviews Gastroenterology & Hepatology Year: 2012 Reference: Nat Rev Gastroenterol Hepatol. 2012 Oct;9(10):599-608. doi: 10.1038/nrgastro.2012.152. Epub 2012 Aug 21. Impact factor: 8.102 Publication type: Review in international publication Authors: Manichanh, Chaysavanh, Borruel, Natalia, Casellas, Francesc, Guarner, Francisco et al. DOI: 10.1038/nrgastro.2012.152
PMID: 22846661 Journal: BMC MICROBIOLOGY Year: 2012 Reference: BMC Microbiol. 2012 Jul 30;12:158. doi: 10.1186/1471-2180-12-158. Impact factor: 3.044 Publication type: Paper in international publication Authors: Cardona, Silvia, Eck, Anat, Cassellas, Montserrat, Gallart, Milagros, Alastrue, Carmen, Dore, Joel, Azpiroz, Fernando, Roca, Joaquim, Guarner, Francisco, Manichanh, Chaysavanh et al. DOI: 10.1186/1471-2180-12-158
PMID: 21852363 Journal: AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY Year: 2011 Reference: Am J Physiol Gastrointest Liver Physiol. 2011 Nov;301(5):G846-55. Epub 2011 Aug 18. Impact factor: 3.522 Publication type: Paper in international publication Authors: , , , , , et al. DOI: 10.1152/ajpgi.00485.2010
PMID: 20938444 Journal: INTERNATIONAL JOURNAL OF OBESITY Year: 2011 Reference: Int J Obes (Lond). 2011 Jun;35(6):829-37. doi: 10.1038/ijo.2010.210. Epub 2010 Oct 12. Impact factor: 5.125 Publication type: Paper in international publication Authors: , , , , , , , , , et al. DOI: 10.1038/ijo.2010.210
PMID: 21736772 Journal: BRITISH JOURNAL OF NUTRITION Year: 2011 Reference: Br J Nutr. 2011 Dec;106(11):1765-7. Epub 2011 Jun 21. Impact factor: 3.072 Publication type: Letter or abstract Authors: , , , , , , , , , et al. DOI: 10.1017/S0007114511002248
PMID: 21734393 Journal: DIGESTIVE DISEASES Year: 2011 Reference: Dig Dis. 2011;29(2):255-63. Epub 2011 Jul 5. Impact factor: 1 Publication type: Paper in international publication Authors: Malagelada, Juan-R et al. DOI: 10.1159/000323931
PMID: 20582743 Journal: Curr Gastroenterol Rep Year: 2010 Reference: Curr Gastroenterol Rep. 2010 Aug;12(4):242-8. Impact factor: Publication type: Letter or abstract Authors: Malagelada, Carolina, Malagelada, Juan-R et al. DOI: 10.1007/s11894-010-0119-y
PMID: 21142381 Journal: REVISTA ESPANOLA DE ENFERMEDADES DIGESTIVAS Year: 2010 Reference: Rev Esp Enferm Dig. 2010 Nov;102(11):621-623. Impact factor: 0.994 Publication type: Editorial in national publication Authors: et al. DOI:
PMID: 21122573 Journal: Journal of Crohns & Colitis Year: 2010 Reference: J Crohns Colitis. 2010 Dec;4(6):637-41. Epub 2010 Aug 2. Impact factor: 1.729 Publication type: Paper in international publication Authors: Pelaez, A, Torrejon, A, Castells, I, Masachs, M, Varela, E, Guarner, F, Borruel, N, Casellas, F, Huaman, Jw et al. DOI: 10.1016/j.crohns.2010.07.006
PMID: 21122570 Journal: Journal of Crohns & Colitis Year: 2010 Reference: J Crohns Colitis. 2010 Dec;4(6):611-22. Epub 2010 Sep 17. Impact factor: 1.729 Publication type: Review in international publication Authors: Hernandez-Sampelayo, Paloma, Seoane, Montserrat, Oltra, Lorena, Marin, Laura, Torrejon, Antonio, Vera, Maria Isabel, Garcia, Valle, Lazaro, Pablo, Parody, Elizabeth, Blasco, Antonio J et al. DOI: 10.1016/j.crohns.2010.08.009
PMID: 19524118 Journal: Gastroenterol Hepatol Year: 2009 Reference: Gastroenterol Hepatol. 2009 May;32 Suppl 1:1-14. Impact factor: Publication type: Letter or abstract Authors: Mearin, Fermin, Guarner, Francisco, Verdu, Elena et al. DOI: 10.1016/S0210-5705(09)71003-9
PMID: 19614865 Journal: NEUROGASTROENTEROLOGY AND MOTILITY Year: 2009 Reference: Neurogastroenterol Motil. 2009 Dec;21(12):1264-e119. Impact factor: 3.48 Publication type: Paper in international publication Authors: de Iorio, F, Malagelada, C, Azpiroz, F, Maluenda, M, Violanti, C, Igual, L, Vitria, J, Malagelada, J-R et al. DOI: 10.1111/j.1365-2982.2009.01363.x
PMID: 19585519 Journal: JOURNAL OF PATHOLOGY Year: 2009 Reference: J Pathol. 2009 Oct;219(2):205-13. Impact factor: 5.121 Publication type: Paper in international publication Authors: Martinez-Romero, Carles, Rooman, Ilse, Skoudy, Anouchka, Guerra, Carmen, Molero, Xavier, Gonzalez, Ana, Iglesias, Mar, Lobato, Tania, Bosch, Almudena, Barbacid, Mariano et al. DOI: 10.1002/path.2585
PMID: 19512936 Journal: EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY Year: 2009 Reference: Eur J Gastroenterol Hepatol. 2009 Dec;21(12):1333-9. Impact factor: 2.08 Publication type: Paper in international publication Authors: Saperas, Esteve, Videla, Sebastian, Bayarri, Carolina, Lobo, Beatriz, Abu-Suboh, Monder, Armengol, Jose Ramon, Malagelada, Juan R, Dot, Joan et al. DOI: 10.1097/MEG.0b013e32830e491c
PhD student: Cristina Pardo Camacho Director/s: Fco Javier Santos Vicente, Maria Vicario Perez University: Universidad Autònoma de Barcelona Year: 2020
Among the genes described, there are some related to digestive system functions, which reinforces the biological entity of irritable bowel syndrome as a digestive disease.
The international study, in which Vall d'Hebron participated, monitored patients who were hospitalized for COVID-19 for 12 months and compared their gastrointestinal symptoms with another group of patients diagnosed with other medical pathologies.
Els estudis avançaran en els camps de les malalties digestives, el VIH, la fatiga crònica, les patologies cardíaques, l’hepatitis, la diabetis i l’oftalmologia.
