About the VHIR
Here at the Vall d'Hebron Research Institute (VHIR) we promote biomedical research, innovation and teaching. Over 1,800 people are seeking to understand diseases today so the treatment can be improved tomorrow.
Research
We are working to understand diseases, to find out how they operate and to create better treatments for patients. Get to know about our groups and their lines of research.
People
People are the centre of the Vall d'Hebron Research Institute (VHIR). This is why we are bound by the principles of freedom of research, gender equality and professional attitudes that HRS4R promotes.
Clinical trials
Our work is not just basic or translational; we are leaders in clinical research. Enter and find about the clinical trials we are conducting and why we are a world reference in this field.
Progress
Our aim is to make the research carried out at the Vall d’Hebron Research Institute (VHIR) a driving force for transformation. How? By identifying new channels and solutions for the promotion of people's health and well-being.
Core facilities
We offer specialist support for researchers, internal and external alike, ranging from specific services to preparing complete projects. All this, from a perspective of quality and speed of response.
News
We offer you a gateway for staying up to date on everything going on at the Vall d’Hebron Research Institute (VHIR), from the latest news to future solidarity activities and initiatives that we are organising.
The Research group on Aging, Frailty and Care Transitions in Barcelona (REFiTBcn) stems from the expertise of healthcare professionals of Parc Sanitari Pere Virgili. The group focuses on clinical epidemiology of aging and implementation science of innovative and integrated complex interventions, with the final aim of improving quality of life of older adults, from prevention and promotion of healthy aging to management of frailty.
The main research line include: cardiovascular risk, cognitive impairment and mobility disability; shared decisions and individualized management to improve rehabilitation of stroke and cancer survivors; management of delirium; integrated care in the community to prevent disability or to improve homecare.
The group maintains top-level international collaborations with Swedish, Canadian, Italian and US centres.
This line includes projects focused on frailty, on the association between cognitive function, cognitive impairment and physical function, or on exercise and physical activity, either from a clinical, pathophysiological or epidemiological viewpoint, as well as focused on the implementation, in the real context, of new models of care.
Ongoing projects: MEDPHOTAGE (non-invasive measurement of blood flow and cerebral metabolism during cognitive and physical tests, funded by the Carlos III Institute, DTS, in collaboration with the Institute of Photonic Sciences - ICFO), DIALCAT (diabetes and Alzheimer's disease, multi-centric observational and intervention project, funded by RIS3Cat-FEDER), + ÀGIL Bcn (implementation of a complex community intervention to prevent disability in frail older people, self-financed in collaboration with the Catalan Health Institute - ICS).
IP: Marco Inzitari
This line includes projects focused on improving clinical interventions in geriatric rehabilitation, especially in people who have suffered a stroke, optimizing the process of rehabilitation and recovery, in the hospital or home setting, always maintaining an optics of person-centered care.
Ongoing projects: IMAGINE (motivational interviewing to promote rehabilitation after a stroke, funded by the Fundació La Marató de TV3).
This line is cross-sectional to the others, based on qualitative methods of assessing the experience and involvement of the person, their caregivers, and of the professionals, in the case of the implementation of complex interventions
This line includes projects of translational research and organizational innovation closely linked to geriatric care, which aim to promote safe care transitions, as well as the adherence to different treatments and the recovery of an active life at home, with the ultimate goal of reducing complications and the rate of hospital readmissions.
Ongoing projects: TransitionA (complex person-centered non-pharmacological intervention, aimed to empower the persons before the transition and to prepare them for return home), Comprehensive Geriatric Hospital at Home (both with own funding).
IP: Marco Inzitari Collaborators: - Funding agency: Ajuntament Barcelona Funding: 56925 Reference: FRAILWATCH Duration: 10/11/2023 - 10/05/2025
IP: Mariona Esquerdo Barragán Collaborators: Rafael José Navajo Garrido, Maria Lourdes Reula Sanz, Judit Domingo Prim, María Garrido Martínez, Adrià Escolà Cerqueda, Alejandra de la Cruz Trillo, Gabriela Isabel Fuentes Llopis, Alonso Javier Parron Yuste, Marco Inzitari, Nunzio Gennaro Cifariello Funding agency: Instituto de Salud Carlos III Funding: 408900 Reference: PT23/00052 Duration: 01/01/2024 - 31/12/2026
IP: Monica Rodriguez Carballeira Collaborators: Montserrat Juárez Vives, Aida Ribera Sole, Mireia Arnedo Valero, Daniel Sevilla Sánchez, Marcos Pérez Carrasco, Jordi Bañeras Rius, Marta Molins Sauri, Laura Mónica Perez Bazan, Neus Gual Tarrada, Meritxell Jiménez Llahí, Ana Maria De Andres Lázaro, Ignasi Maspons Molins, Cristina Udina Argilaga, Lorena Villa García, Marco Inzitari, Sofia Contreras Medina Funding agency: Agència Gestió Ajuts Universitaris i de Recerca Funding: 0.01 Reference: 2022 XARDI 00021 Duration: 01/01/2023 - 31/12/2025
IP: Laura Mónica Perez Bazan Collaborators: Aida Ribera Sole, Lorena Villa García Funding agency: Ajuntament Barcelona Funding: 59796.5 Reference: 22S09412-0016 Duration: 23/12/2022 - 23/06/2024
PMID: 36960983 Journal: Geriatrics (Basel, Switzerland) Year: 2023 Reference: Geriatrics (Basel). 2023 Feb 22;8(2):28. doi: 10.3390/geriatrics8020028. Impact factor: Publication type: Review in international publication Authors: Bellelli, Giuseppe; Cavalli, Stefano; Morandi, Alessandro; Pozzi, Christian; Strasser-Gugerell, Cornelia; Tatzer, Verena C et al. DOI: 10.3390/geriatrics8020028
PMID: 36960372 Journal: Frontiers in Public Health Year: 2023 Reference: Front Public Health. 2023 Mar 7;11:1062843. doi: 10.3389/fpubh.2023.1062843. eCollection 2023. Impact factor: Publication type: Paper in international publication Authors: Castellano-Tejedor, Carmina; Davey, Vanessa; Diaz, Pako; Gine-Garriga, Maria; Inzitari, Marco; Kuluski, Kerry; Perez, Laura M; Risco, Ester; Soto-Bagaria, Luis; Villa-Garcia, Lorena et al. DOI: 10.3389/fpubh.2023.1062843
PMID: 37052832 Journal: European Geriatric Medicine Year: 2023 Reference: Eur Geriatr Med. 2023 Jun;14(3):485-492. doi: 10.1007/s41999-023-00773-2. Epub 2023 Apr 13. Impact factor: Publication type: Paper in international publication Authors: Bellelli, Giuseppe; Gentile, Simona; Grossi, Eleonora; Guarneri, Barbara; Inzitari, Marco; Morandi, Alessandro; Rocco, Chiara; Stilo, Leone et al. DOI: 10.1007/s41999-023-00773-2
PMID: 37957601 Journal: BMC Geriatrics Year: 2023 Reference: BMC Geriatr. 2023 Nov 13;23(1):736. doi: 10.1186/s12877-023-04292-4. Impact factor: Publication type: Paper in international publication Authors: Abilla, Araceli; Arnal, Cristina; Ars, Joan; Baro, Sonia; Cesari, Matteo; Diaz, Francisco; Enfedaque, M Belen; Ferrer-Marquez, Manuel; FrutosBernal, M Dolores; Garcia-Redondo, Manuel et al. DOI: 10.1186/s12877-023-04292-4
PMID: 34058062 Journal: IUBMB LIFE Year: 2022 Reference: IUBMB Life. 2022 Jan;74(1):74-84. doi: 10.1002/iub.2507. Epub 2021 May 31. Impact factor: 3.885 Publication type: Review in international publication Authors: Olaso-Gonzalez, Gloria; Inzitari, Marco; Bellelli, Giuseppe; Morandi, Alessandro; Barcons, Nuria; Vina, Jose et al. DOI: 10.1002/iub.2507
PMID: 35157252 Journal: European Geriatric Medicine Year: 2022 Reference: Eur Geriatr Med. 2022 Apr;13(2):505-506. doi: 10.1007/s41999-022-00611-x. Impact factor: 1.71 Publication type: Editorail in international publication Authors: Soulis, George; Inzitari, Marco et al. DOI: 10.1007/s41999-022-00611-x
PMID: 34417734 Journal: AGING CLINICAL AND EXPERIMENTAL RESEARCH Year: 2022 Reference: Aging Clin Exp Res. 2022 Feb;34(2):349-357. doi: 10.1007/s40520-021-01950-8. Epub 2021 Aug 20. Impact factor: 3.638 Publication type: Paper in international publication Authors: Minaglia, C; Tarasconi, A; Sella, M; Auriemma, S; Paterno, G; Faggian, G; Lucarelli, C; De Grazia, N; Alberto, C; Margola, A et al. DOI: 10.1007/s40520-021-01950-8
PMID: 35732390 Journal: BMJ Open Year: 2022 Reference: BMJ Open. 2022 Jun 22;12(6):e060822. doi: 10.1136/bmjopen-2022-060822. Impact factor: 2.692 Publication type: Paper in international publication Authors: Lusilla-Palacios, Pilar; Ramos-Quiroga, Jose Antonio; Vazquez-De Sebastian, Julia; Puig, Gemma Parramon; Ciudin, Andreea; Comas, Marta; Cano Porras, Desiderio; Spanlang, Bernhard; Slater, Mel; Anastasiadou, Dimitra et al. DOI: 10.1136/bmjopen-2022-060822
PMID: 34549243 Journal: The Journal of frailty & aging Year: 2021 Reference: J Frailty Aging. 2021;10(4):310-312. doi: 10.14283/jfa.2021.23. Impact factor: 0 Publication type: Editorail in international publication Authors: Cesari, M, Calvani, R, Canevelli, M, Aprahamian, I, de Souto Barreto, P, Azzolino, D, Fielding, R A, Vanacore, N, Inzitari, M, Marzetti, E et al. DOI: 10.14283/jfa.2021.23
PMID: 34105716 Journal: The Journal of frailty & aging Year: 2021 Reference: J Frailty Aging. 2021;10(3):297-300. doi: 10.14283/jfa.2021.1. Impact factor: 0 Publication type: Paper in international publication Authors: Udina, C, Ars, J, Morandi, A, Vilaro, J, Caceres, C, Inzitari, M et al. DOI: 10.14283/jfa.2021.1
PMID: 34899582 Journal: Frontiers in Neurology Year: 2021 Reference: Front Neurol. 2021 Nov 25;12:767484. doi: 10.3389/fneur.2021.767484. eCollection 2021. Impact factor: 4.003 Publication type: Paper in international publication Authors: Tejada, Pedro Ignacio, Garcia-Rodriguez, Nicolas, Rodriguez, Susana, Buxo, Xavi, Perez-Mesquida, Maria Engracia, Beseler, Maria Rosario, Salom, Juan B, Perez, Laura M, Inzitari, Marco, Otero-Villaverde, Sergio et al. DOI: 10.3389/fneur.2021.767484
PMID: 34844780 Journal: Rehabilitacion Year: 2021 Reference: Rehabilitacion (Madr). 2021 Oct 30. pii: S0048-7120(21)00104-3. doi: 10.1016/j.rh.2021.10.002. Impact factor: 0 Publication type: Paper in national publication Authors: Llarch-Pinell, E, Monso-Monso, A, Ars, J, Udina, C, Inzitari, M, Grau-Sanchez, J et al. DOI: 10.1016/j.rh.2021.10.002
PMID: 33244558 Journal: Journal of Nutrition Health & Aging Year: 2020 Reference: J Nutr Health Aging. 2020;24(10):1042-1046. doi: 10.1007/s12603-020-1447-8. Impact factor: 2.791 Publication type: Editorail in international publication Authors: Inzitari, M, Risco, E, Cesari, M, Buurman, B M, Kuluski, K, Davey, V, Bennett, L, Varela, J, Prvu Bettger, J et al. DOI: 10.1007/s12603-020-1447-8
PMID: 33049559 Journal: NURSE EDUCATION TODAY Year: 2020 Reference: Nurse Educ Today. 2020 Dec;95:104582. doi: 10.1016/j.nedt.2020.104582. Epub 2020 Sep 5. Impact factor: 2.49 Publication type: Review in international publication Authors: Pedregosa, Sara, Fabrellas, Nuria, Risco, Ester, Pereira, Mariana, Dmoch-Gajzlerska, Ewa, Senuzun, Fisun, Martin, Sandra, Zabalegui, Adelaida et al. DOI: 10.1016/j.nedt.2020.104582
PMID: 32887564 Journal: BMC Geriatrics Year: 2020 Reference: BMC Geriatr. 2020 Sep 4;20(1):321. doi: 10.1186/s12877-020-01694-6. Impact factor: 3.077 Publication type: Paper in international publication Authors: Gual, Neus, Perez, Laura Monica, Castellano-Tejedor, Carmina, Lusilla-Palacios, Pilar, Castro, Judith, Soto-Bagaria, Luis, Coll-Planas, Laura, Roque, Marta, Vena, Ana Belen, Fontecha, Benito et al. DOI: 10.1186/s12877-020-01694-6
PMID: 32754841 Journal: European Geriatric Medicine Year: 2020 Reference: Eur Geriatr Med. 2020 Dec;11(6):961-974. doi: 10.1007/s41999-020-00365-4. Epub 2020 Aug 4. Impact factor: 1.232 Publication type: Review in international publication Authors: Sezgin, Duygu, O'Caoimh, Ronan, Liew, Aaron, O'Donovan, Mark R, Illario, Maddelena, Salem, Mohamed A, Kennelly, Siobhan, Carriazo, Ana Maria, Lopez-Samaniego, Luz, Carda, Cristina Arnal et al. DOI: 10.1007/s41999-020-00365-4
PMID: 32038224 Journal: Frontiers in Aging Neuroscience Year: 2019 Reference: Front Aging Neurosci. 2020 Jan 21;11:367. doi: 10.3389/fnagi.2019.00367. eCollection 2019. Impact factor: 3.633 Publication type: Review in international publication Authors: Inzitari, Marco, Soto-Bagaria, Luis, Perez, Laura-Monica, Udina, Cristina, Avtzi, Stella, Durduran, Turgut, Holtzer, Roee, Rosso, Andrea L, Castellano-Tejedor, Carmina et al. DOI: 10.3389/fnagi.2019.00367
PMID: 31560028 Journal: Journal of Nutrition Health & Aging Year: 2019 Reference: J Nutr Health Aging. 2019;23(8):710-716. doi: 10.1007/s12603-019-1244-4. Impact factor: 2.66 Publication type: Paper in international publication Authors: Perez, L M, Enfedaque-Montes, M B, Cesari, M, Soto-Bagaria, L, Gual, N, Burbano, M P, Tarazona-Santabalbina, F J, Casas, R M, Diaz, F, Martin, E et al. DOI: 10.1007/s12603-019-1244-4
PMID: 31311165 Journal: International Journal of Environmental Research and Public Health Year: 2019 Reference: Int J Environ Res Public Health. 2019 Jul 15;16(14). pii: ijerph16142527. doi: 10.3390/ijerph16142527. Impact factor: 2.468 Publication type: Review in international publication Authors: Guerra-Balic, Myriam, Sansano-Nadal, Oriol, Gine-Garriga, Maria, Brach, Jennifer S, Wert, David M, Jerez-Roig, Javier, Gomara-Toldra, Natalia, Soto-Bagaria, Luis, Perez, Laura Monica, Inzitari, Marco et al. DOI: 10.3390/ijerph16142527
PMID: 31288087 Journal: EXPERIMENTAL GERONTOLOGY Year: 2019 Reference: Exp Gerontol. 2019 Sep;124:110652. doi: 10.1016/j.exger.2019.110652. Epub 2019 Jul 6. Impact factor: 3.08 Publication type: Paper in international publication Authors: Inzitari, Marco, Metti, Andrea, Rosano, Caterina, Perez, Laura M, Carrizo, Gabriela, Verghese, Joe, Newman, Anne B, Studenski, Stephanie, Rosso, Andrea L, Udina, Cristina et al. DOI: 10.1016/j.exger.2019.110652
PMID: 30379309 Journal: Journal of Nutrition Health & Aging Year: 2018 Reference: J Nutr Health Aging. 2018;22(9):1099-1106. doi: 10.1007/s12603-018-1060-2. Impact factor: 2.868 Publication type: Paper in international publication Authors: Calle, A, Onder, G, Morandi, A, Bellelli, G, Ortolani, E, Perez, L M, Mesas, M, Sanniti, A, Mazzanti, P, Platto, C N et al. DOI: 10.1007/s12603-018-1060-2
PMID: 30268290 Journal: Journal of the American Medical Directors Association Year: 2018 Reference: J Am Med Dir Assoc. 2018 Oct;19(10):860-863. doi: 10.1016/j.jamda.2018.06.013. Impact factor: 5.325 Publication type: Paper in international publication Authors: Santaeugenia, Sebastia J, Tarazona-Santabalbina, Francisco J, Gamez, Sara, Inzitari, Marco, Mas, Miquel A et al. DOI: 10.1016/j.jamda.2018.06.013
PMID: 30145055 Journal: European Journal of Internal Medicine Year: 2018 Reference: Eur J Intern Med. 2018 Oct;56:57-63. doi: 10.1016/j.ejim.2018.07.022. Epub 2018 Aug 23. Impact factor: 3.282 Publication type: Paper in international publication Authors: Inzitari, Marco, Perez, Laura Monica, Enfedaque, M Belen, Soto, Luis, Diaz, Francisco, Gual, Neus, Martin, Elisabeth, Orfila, Francesc, Mulero, Paola, Ruiz, Rafael et al. DOI: 10.1016/j.ejim.2018.07.022
PMID: 30131288 Journal: AMERICAN JOURNAL OF GERIATRIC PSYCHIATRY Year: 2018 Reference: Am J Geriatr Psychiatry. 2018 Dec;26(12):1204-1212. doi: 10.1016/j.jagp.2018.07.003. Epub 2018 Jul 20. Impact factor: 3.48 Publication type: Paper in international publication Authors: Yuste, Anna, Gual, Neus, Inzitari, Marco, Carrizo, Gabriela, Calle, Alicia, Udina, Cristina, Morandi, Alessandro et al. DOI: 10.1016/j.jagp.2018.07.003
PMID: 29188910 Journal: Emergencias Year: 2017 Reference: Emergencias. 2017 Dic;29(6):371-372. Impact factor: 3.028 Publication type: Editorail in international publication Authors: de Andres Lazaro, Ana M feminine et al. DOI:
PMID: 26948303 Journal: Revista espanola de geriatria y gerontologia Year: 2017 Reference: Rev Esp Geriatr Gerontol. 2017 Mar - Apr;52(2):75-79. doi: 10.1016/j.regg.2015.12.007. Epub 2016 Mar 3. Impact factor: 0 Publication type: Paper in national publication Authors: Colprim, Daniel, Casco, Monica, Malumbres, Jennifer, Rodriguez, Gines, Inzitari, Marco et al. DOI: 10.1016/j.regg.2015.12.007
PMID: 27544014 Journal: Revista espanola de geriatria y gerontologia Year: 2017 Reference: Rev Esp Geriatr Gerontol. 2017 May - Jun;52(3):159-166. doi: 10.1016/j.regg.2016.07.005. Epub 2016 Aug 17. Impact factor: 0 Publication type: Paper in national publication Authors: Amblas-Novellas, Jordi, Espaulella-Panicot, Joan, Inzitari, Marco, Rexach, Lourdes, Fontecha, Benito, Romero-Ortuno, Roman et al. DOI: 10.1016/j.regg.2016.07.005
PMID: 27978445 Journal: NURSE EDUCATION TODAY Year: 2017 Reference: Nurse Educ Today. 2017 Feb;49:163-167. doi: 10.1016/j.nedt.2016.11.028. Epub 2016 Dec 7. Impact factor: 2.533 Publication type: Paper in international publication Authors: Pulpon, Anna M, Morin, Victoria, Sancho, Raul, Cleries, Xavier, Fabrellas, Nuria, Sola, Montserrat et al. DOI: 10.1016/j.nedt.2016.11.028
PMID: NOPMID041 Journal: European Geriatric Medicine Year: 2016 Reference: European Geriatric Medicine. 2016: 7: 224-231 Impact factor: 1.326 Publication type: Paper in international publication Authors: , , , , , , , et al. DOI: 10.1016/j.eurger.2015.11.001
PMID: 25910548 Journal: ARCHIVOS DE BRONCONEUMOLOGIA Year: 2016 Reference: Arch Bronconeumol. 2016 Mar;52(3):131-7. doi: 10.1016/j.arbres.2015.02.009. Epub 2015 Apr 21. Impact factor: 1.771 Publication type: Paper in national publication Authors: Cleries, Xavier, Sola, Montserrat, Chiner, Eusebi, Escarrabill, Joan et al. DOI: 10.1016/j.arbres.2015.02.009
PMID: 27105701 Journal: MATURITAS Year: 2016 Reference: Maturitas. 2016 Jun;88:65-9. doi: 10.1016/j.maturitas.2016.03.005. Epub 2016 Mar 11. Impact factor: 3.12 Publication type: Paper in international publication Authors: Inzitari, Marco, Mas, Miquel Angel, Closa, Conxita, Santaeugenia, Sebastia J, Gallofre, Miquel, Ribera, Aida et al. DOI: 10.1016/j.maturitas.2016.03.005
PMID: 27163817 Journal: JOURNAL OF ALZHEIMERS DISEASE Year: 2016 Reference: J Alzheimers Dis. 2016 May 7;53(2):505-15. doi: 10.3233/JAD-160087. Impact factor: 3.92 Publication type: Paper in international publication Authors: Di Carlo, Antonio, Baldereschi, Marzia, Lamassa, Maria, Bovis, Francesca, Inzitari, Marco, Solfrizzi, Vincenzo, Panza, Francesco, Galluzzo, Lucia, Scafato, Emanuele, Inzitari, Domenico et al. DOI: 10.3233/JAD-160087
PhD student: Neus Gual Tarrada Director/s: Marco Inzitari , Albert Selva O'Callaghan University: Universidad Autònoma de Barcelona Year: 2019
PhD student: Alicia Calle Egusquiza Director/s: Marco Inzitari University: Universidad Autònoma de Barcelona Year: 2018
The two centres call on people with a diagnosis of cancer over 65-years-old and living in Barcelona to participate in the trial.
The Barcelona Aging coLLaboratory (BALL) aims to create innovative solutions, with the participation of end users, to improve quality of life and health and social care for the elderly.
Entre els projectes es troben 12 investigacions on participen investigadors i investigadores de Vall d’Hebron.
PROFIT study: It evaluates the benefits of physical exercise in people over 65 who suffer from lung, prostate or gastrointestinal cancer.
FRONTSTAGE study: It evaluates the effect of physical exercise on the physical and cognitive function of elderly people with mild mobility and memory problems.
