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Research on Aging, Frailty and Transitions in Barcelona

The Research group on Aging, Frailty and Care Transitions in Barcelona (REFiTBcn) stems from the expertise of healthcare professionals of Parc Sanitari Pere Virgili. The group focuses on clinical epidemiology of aging and implementation science of innovative and integrated complex interventions, with the final aim of improving quality of life of older adults, from prevention and promotion of healthy aging to management of frailty.

The main research line include: cardiovascular risk, cognitive impairment and mobility disability; shared decisions and individualized management to improve rehabilitation of stroke and cancer survivors; management of delirium; integrated care in the community to prevent disability or to improve homecare. 

The group maintains top-level international collaborations with Swedish, Canadian, Italian and US centres.

Team

Lorena Villa García

Lorena Villa García

Predoctoral researcher
Research on Aging, Frailty and Transitions in Barcelona
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Luis Ignacio Soto Bargaria

Luis Ignacio Soto Bargaria

Predoctoral researcher
Research on Aging, Frailty and Transitions in Barcelona
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Marco Inzitari

Marco Inzitari

Head of group
Research on Aging, Frailty and Transitions in Barcelona
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Margarita  Sanchez-Arcilla Rosanas

Margarita Sanchez-Arcilla Rosanas

Predoctoral researcher
Research on Aging, Frailty and Transitions in Barcelona
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Neus Gual Tarrada

Neus Gual Tarrada

Predoctoral researcher
Research on Aging, Frailty and Transitions in Barcelona
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Paula Espí Vallvé

Paula Espí Vallvé

Administration and Management
Research on Aging, Frailty and Transitions in Barcelona
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Lorena Villa García

Lorena Villa García

Predoctoral researcher
Research on Aging, Frailty and Transitions in Barcelona
Read more
Luis Ignacio Soto Bargaria

Luis Ignacio Soto Bargaria

Predoctoral researcher
Research on Aging, Frailty and Transitions in Barcelona
Read more
Marco Inzitari

Marco Inzitari

Head of group
Research on Aging, Frailty and Transitions in Barcelona
Read more
Margarita  Sanchez-Arcilla Rosanas

Margarita Sanchez-Arcilla Rosanas

Predoctoral researcher
Research on Aging, Frailty and Transitions in Barcelona
Read more
Neus Gual Tarrada

Neus Gual Tarrada

Predoctoral researcher
Research on Aging, Frailty and Transitions in Barcelona
Read more
Paula Espí Vallvé

Paula Espí Vallvé

Administration and Management
Research on Aging, Frailty and Transitions in Barcelona
Read more

Publications

Association Between Accelerometer-Assessed Physical Activity and Cognitive Function in Older Adults: A Cross-Sectional Study.

PMID: 39428265
Journal: AMERICAN JOURNAL OF GERIATRIC PSYCHIATRY
Year: 2024
Reference: Am J Geriatr Psychiatry. 2024 Oct 9:S1064-7481(24)00481-0. doi: 10.1016/j.jagp.2024.09.017.
Impact factor:
Publication type: Paper in international publication
Authors: Ars, Joan; Beridze, Giorgi; Calderon-Larranaga, Amaia; Farres-Godayol, Pau; Inzitari, Marco; Laukka, Erika J; Perez, Laura M; Welmer, Anna-Karin et al.
DOI: 10.1016/j.jagp.2024.09.017

Relationship Between Instagram, Body Satisfaction, and Self-Esteem in Early Adulthood.

PMID: 39517366
Journal: Healthcare
Year: 2024
Reference: Healthcare (Basel). 2024 Oct 29;12(21):2153. doi: 10.3390/healthcare12212153.
Impact factor:
Publication type: Paper in international publication
Authors: Castellano-Tejedor, Carmina; Flores Mata, Cristina et al.
DOI: 10.3390/healthcare12212153

World delirium awareness and quality survey in 2023-a worldwide point prevalence study.

PMID: 39568389
Journal: AGE AND AGEING
Year: 2024
Reference: Age Ageing. 2024 Nov 1;53(11):afae248. doi: 10.1093/ageing/afae248.
Impact factor:
Publication type: Paper in international publication
Authors: Ashkenazy, Shelly; Bellelli, Giuseppe; Caplan, Gideon; Chung, Chi Ryang; Collet, Marie Oxenboell; Elhadi, Muhammed; Gurjar, Mohan; Heras-La-Calle, Gabriel; Hoffman, Magdalena; Jeitziner, Marie-Madlen et al.
DOI: 10.1093/ageing/afae248

Costs during the first year after stroke by degree of functional disability: A societal perspective.

PMID: 39614654
Journal: European Stroke Journal
Year: 2024
Reference: Eur Stroke J. 2024 Nov 30:23969873241301904. doi: 10.1177/23969873241301904.
Impact factor:
Publication type: Paper in international publication
Authors: Abilleira, Sonia; Aznar-Lou, Ignacio; Perez de la Osa, Natalia; Ribera, Aida; Ribo, Marc; Salvat-Plana, Merce; Sanchez-Vinas, Alba; Serrano-Blanco, Antoni; Slof, John; Soler-Font, Merce et al.
DOI: 10.1177/23969873241301904

Biofeedback and Digitalized Motivational Interviewing to Increase Daily Physical Activity: Series of Factorial N-of-1 Randomized Controlled Trials Piloting the Precious App.

PMID: 37995122
Journal: JMIR formative research
Year: 2023
Reference: JMIR Form Res. 2023 Nov 23;7:e34232. doi: 10.2196/34232.
Impact factor:
Publication type: Paper in international publication
Authors: Castellano-Tejedor, Carmina; Gartner, Silvia; Ginchev, Todor; Haukkala, Ari; Iglesias Serrano, Ignacio; Izquierdo, Ana Diez; Khattak, Fida; Knittle, Keegan; Lusilla-Palacios, Pilar; Messa, Ines Mir et al.
DOI: 10.2196/34232

Key Genes of the Immune System and Predisposition to Acquired Hemophilia A: Evidence from a Spanish Cohort of 49 Patients Using Next-Generation Sequencing.

PMID: 38003562
Journal: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Year: 2023
Reference: Int J Mol Sci. 2023 Nov 15;24(22):16372. doi: 10.3390/ijms242216372.
Impact factor:
Publication type: Paper in international publication
Authors: Aguinaco, Reyes; Astigarraga, Itziar; Bastida, Jose Maria; Bernardo, Angel; Carrasco, Marina; Castellano-Tejedor, Carmina; Closa, Laia; Corrales, Irene; Ferrero, Ainara; Garcia-Martinez, Iris et al.
DOI: 10.3390/ijms242216372

Predicting 60-Day Mortality in a Home-Care Service: Development of a New Inter-RAI 49-Frailty Index in Patients With Chronic Disease and Without a Cancer Diagnosis.

PMID: 38081326
Journal: Journal of the American Medical Directors Association
Year: 2023
Reference: J Am Med Dir Assoc. 2023 Dec 8:S1525-8610(23)00943-X. doi: 10.1016/j.jamda.2023.10.028.
Impact factor:
Publication type: Paper in international publication
Authors: Bellelli, Giuseppe; Crippa, Matteo; Lombardi, Fabio; Mazzola, Paolo; Morandi, Alessandro; Re, Massimo; Riva, Luca; Scaccabarozzi, Gianlorenzo; Zambon, Antonella et al.
DOI: 10.1016/j.jamda.2023.10.028

Mobile applications to prescribe physical exercise in frail older adults: review of the available tools in app stores.

PMID: 38157286
Journal: AGE AND AGEING
Year: 2023
Reference: Age Ageing. 2023 Dec 1;52(12):afad227. doi: 10.1093/ageing/afad227.
Impact factor:
Publication type: Paper in international publication
Authors: Andres-Peiro, Jose Vicente; Blasco-Casado, Ferran; Carrion, Carme; Castellet-Feliu, Enric; de Sola-Morales, Oriol; Eis, Sophie; Garcia-Albo, Enrique; Gine-Garriga, Maria; Inzitari, Marco; Joshi-Jubert, Nayana et al.
DOI: 10.1093/ageing/afad227

Clinical efficacy of a virtual reality tool for the treatment of obesity: study protocol of a randomised controlled trial.

PMID: 35732390
Journal: BMJ Open
Year: 2022
Reference: BMJ Open. 2022 Jun 22;12(6):e060822. doi: 10.1136/bmjopen-2022-060822.
Impact factor:
Publication type: Paper in international publication
Authors: Anastasiadou, Dimitra; Cano Porras, Desiderio; Ciudin, Andreea; Comas, Marta; Lusilla-Palacios, Pilar; Puig, Gemma Parramon; Ramos-Quiroga, Jose Antonio; Slater, Mel; Spanlang, Bernhard; Vazquez-De Sebastian, Julia et al.
DOI: 10.1136/bmjopen-2022-060822

Editorial: The Management of Frailty: Barking Up the Wrong Tree.

PMID: 35441187
Journal: The Journal of frailty & aging
Year: 2022
Reference: J Frailty Aging. 2022;11(2):127-128. doi: 10.14283/jfa.2022.29.
Impact factor:
Publication type: Editorail in international publication
Authors: Aprahamian, I; Calvani, R; Canevelli, M; Cesari, M; Inzitari, M; Marzetti, E et al.
DOI: 10.14283/jfa.2022.29

Domains of delirium severity in Alzheimer's disease and related dementias.

PMID: 34951704
Journal: JOURNAL OF THE AMERICAN GERIATRICS SOCIETY
Year: 2022
Reference: J Am Geriatr Soc. 2022 May;70(5):1495-1503. doi: 10.1111/jgs.17624. Epub 2021 Dec 24.
Impact factor:
Publication type: Paper in international publication
Authors: Adamis, Dimitrios; Avidan, Michael S; Blazer, Dan G; Fick, Donna M; Hshieh, Tammy; Inouye, Sharon K; Jones, Richard N; Morandi, Alessandro; Oh, Esther; Price, Catherine et al.
DOI: 10.1111/jgs.17624

Delirium and Clusters of Older Patients Affected by Multimorbidity in Acute Hospitals.

PMID: 34798007
Journal: Journal of the American Medical Directors Association
Year: 2022
Reference: J Am Med Dir Assoc. 2022 May;23(5):885-888. doi: 10.1016/j.jamda.2021.10.004. Epub 2021 Nov 16.
Impact factor:
Publication type: Paper in international publication
Authors: Bellelli, Giuseppe; Di Santo, Simona; Marengoni, Alessandra; Monacelli, Fiammetta; Morandi, Alessandro; Rossi, Emanuela; Signori, Alessio; Valsecchi, Maria Grazia et al.
DOI: 10.1016/j.jamda.2021.10.004

Frailty is associated with long-term outcome in patients with sepsis who are over 80 years old: results from an observational study in 241 European ICUs.

PMID: 33744918
Journal: AGE AND AGEING
Year: 2021
Reference: Age Ageing. 2021 Sep 11;50(5):1719-1727. doi: 10.1093/ageing/afab036.
Impact factor:
Publication type: Paper in international publication
Authors: Aguilar, Gerardo; Ahmed, Hazem; Aidoni, Zoi; Aikaterini, Kounougeri; Allgauer, Sebastian; Andersen, Finn H; Andersen, Finn H; Artigas, Antonio; Baird, Yolanda; Balasubramaniam, Madhu et al.
DOI: 10.1093/ageing/afab036

Delirium in Patients with SARS-CoV-2 Infection: A Multicenter Study.

PMID: 33411332
Journal: JOURNAL OF THE AMERICAN GERIATRICS SOCIETY
Year: 2021
Reference: J Am Geriatr Soc. 2021 Feb;69(2):293-299. doi: 10.1111/jgs.16969. Epub 2020 Dec 8.
Impact factor:
Publication type: Paper in international publication
Authors: Bellelli, Giuseppe; Bianchetti, Angelo; Blangiardo, Paolo; Bna, Claudio; Bonfanti, Paolo; Cesaroni, Giulia; Chizzoli, Anita; Citerio, Giuseppe; Faraci, Bianca; Gentile, Simona et al.
DOI: 10.1111/jgs.16969

Two European Examples of Acute Geriatric Units Located Outside of a General Hospital for Older Adults With Exacerbated Chronic Conditions.

PMID: 33524341
Journal: Journal of the American Medical Directors Association
Year: 2021
Reference: J Am Med Dir Assoc. 2021 Jun;22(6):1228-1234. doi: 10.1016/j.jamda.2020.12.034. Epub 2021 Jan 29.
Impact factor:
Publication type: Paper in international publication
Authors: Buurman, Bianca M; Franssen, R; Frenkel, W J; Gual, Neus; Henstra, M J; Inzitari, Marco; Kaland, K J; MacNeil Vroomen, Janet L; Parlevliet, J L; Resodikromo, M N et al.
DOI: 10.1016/j.jamda.2020.12.034

Depressive Symptoms, Fatigue and Social Relationships Influenced Physical Activity in Frail Older Community-Dwellers during the Spanish Lockdown due to the COVID-19 Pandemic.

PMID: 33477879
Journal: International Journal of Environmental Research and Public Health
Year: 2021
Reference: Int J Environ Res Public Health. 2021 Jan 19;18(2). pii: ijerph18020808. doi: 10.3390/ijerph18020808.
Impact factor:
Publication type: Paper in international publication
Authors: Ars, Joan; Baro, Sonia; Castellano-Tejedor, Carmina; Cesari, Matteo; Diaz-Gallego, Francisco; Enfedaque, Maria B; Espi-Valbe, Paula; Inzitari, Marco; Perez, Laura M; Soto-Bagaria, Luis et al.
DOI: 10.3390/ijerph18020808

Engaging Users in the Behavior Change Process With Digitalized Motivational Interviewing and Gamification: Development and Feasibility Testing of the Precious App.

PMID: 32003750
Journal: JMIR mHealth and uHealth
Year: 2020
Reference: JMIR Mhealth Uhealth. 2020 Jan 30;8(1):e12884. doi: 10.2196/12884.
Impact factor:
Publication type: Paper in international publication
Authors: Castellano-Tejedor, Carmina; Costa-Requena, Jose; Ginchev, Todor; Haukkala, Ari; Helf, Christopher; Khattak, Fida; Knittle, Keegan; Lusilla-Palacios, Pilar; Nurmi, Johanna; Ravaja, Niklas et al.
DOI: 10.2196/12884

Editorial: Nursing Homes and Long Term Care after COVID-19: A New Era?

PMID: 33244558
Journal: Journal of Nutrition Health & Aging
Year: 2020
Reference: J Nutr Health Aging. 2020;24(10):1042-1046. doi: 10.1007/s12603-020-1447-8.
Impact factor: 2.791
Publication type: Editorail in international publication
Authors: Inzitari, M, Risco, E, Cesari, M, Buurman, B M, Kuluski, K, Davey, V, Bennett, L, Varela, J, Prvu Bettger, J et al.
DOI: 10.1007/s12603-020-1447-8

Effective academic-practice partnership models in nursing students' clinical placement: A systematic literature review.

PMID: 33049559
Journal: NURSE EDUCATION TODAY
Year: 2020
Reference: Nurse Educ Today. 2020 Dec;95:104582. doi: 10.1016/j.nedt.2020.104582. Epub 2020 Sep 5.
Impact factor: 2.49
Publication type: Review in international publication
Authors: Pedregosa, Sara, Fabrellas, Nuria, Risco, Ester, Pereira, Mariana, Dmoch-Gajzlerska, Ewa, Senuzun, Fisun, Martin, Sandra, Zabalegui, Adelaida et al.
DOI: 10.1016/j.nedt.2020.104582

IMAGINE study protocol of a clinical trial: a multi-center, investigator-blinded, randomized, 36-month, parallel-group to compare the effectiveness of motivational interview in rehabilitation of older stroke survivors.

PMID: 32887564
Journal: BMC Geriatrics
Year: 2020
Reference: BMC Geriatr. 2020 Sep 4;20(1):321. doi: 10.1186/s12877-020-01694-6.
Impact factor: 3.077
Publication type: Paper in international publication
Authors: Gual, Neus, Perez, Laura Monica, Castellano-Tejedor, Carmina, Lusilla-Palacios, Pilar, Castro, Judith, Soto-Bagaria, Luis, Coll-Planas, Laura, Roque, Marta, Vena, Ana Belen, Fontecha, Benito et al.
DOI: 10.1186/s12877-020-01694-6

Qualitative neurological gait abnormalities, cardiovascular risk factors and functional status in older community-dwellers without neurological diseases: The Healthy Brain Project.

PMID: 31288087
Journal: EXPERIMENTAL GERONTOLOGY
Year: 2019
Reference: Exp Gerontol. 2019 Sep;124:110652. doi: 10.1016/j.exger.2019.110652. Epub 2019 Jul 6.
Impact factor: 3.08
Publication type: Paper in international publication
Authors: Inzitari, Marco, Metti, Andrea, Rosano, Caterina, Perez, Laura M, Carrizo, Gabriela, Verghese, Joe, Newman, Anne B, Studenski, Stephanie, Rosso, Andrea L, Udina, Cristina et al.
DOI: 10.1016/j.exger.2019.110652

Home as a Place for Care of the Oldest Stroke Patients: A Pilot from the Catalan Stroke Program.

PMID: 31018014
Journal: JOURNAL OF THE AMERICAN GERIATRICS SOCIETY
Year: 2019
Reference: J Am Geriatr Soc. 2019 Sep;67(9):1979-1981. doi: 10.1111/jgs.15944. Epub 2019 Apr 24.
Impact factor: 4.113
Publication type: Letter whit IF
Authors: Mas, Miquel A, Gamez, Sara, Inzitari, Marco, Ribera, Aida, Santaeugenia, Sebastia J, Gallofre, Miquel, Closa, Conxita et al.
DOI: 10.1111/jgs.15944

[Hospital-at-home Integrated Care Programme tailored to older patients with disabling acute processes: identification of prognostic factors].

PMID: 30792139
Journal: Revista espanola de geriatria y gerontologia
Year: 2019
Reference: Rev Esp Geriatr Gerontol. 2019 May - Jun;54(3):136-142. doi: 10.1016/j.regg.2018.11.005. Epub 2019 Feb 18.
Impact factor: 0
Publication type: Paper in national publication
Authors: Mas, Miquel Angel, Miralles, Ramon, Renom-Guiteras, Anna, Duran, Xavier, Inzitari, Marco et al.
DOI: 10.1016/j.regg.2018.11.005

Nutritional Status and Functional Outcomes in Older Adults Admitted to Geriatric Rehabilitations: The SAFARI Study.

PMID: 30676263
Journal: JOURNAL OF THE AMERICAN COLLEGE OF NUTRITION
Year: 2019
Reference: J Am Coll Nutr. 2019 Jul;38(5):441-446. doi: 10.1080/07315724.2018.1541427. Epub 2019 Jan 24.
Impact factor: 2.08
Publication type: Paper in international publication
Authors: Lelli, Diana, Calle, Alicia, Perez, Laura Monica, Onder, Graziano, Morandi, Alessandro, Ortolani, Elena, Colominas, Miriam, Pedone, Claudio, Inzitari, Marco et al.
DOI: 10.1080/07315724.2018.1541427

[Profile and evolution of chronic complex patients in a subacute unit].

PMID: 28292582
Journal: Atencion Primaria
Year: 2017
Reference: Aten Primaria. 2017 Nov;49(9):510-517. doi: 10.1016/j.aprim.2016.11.010. Epub 2017 Mar 11.
Impact factor: 1.042
Publication type: Paper in national publication
Authors: Inzitari, Marco, Gual, Neus, Yuste Font, Anna, Enfedaque Montes, Belen, Blay Pueyo, Carles, Martin Alvarez, Remedios et al.
DOI: 10.1016/j.aprim.2016.11.010

Hospital-at-home Integrated Care Programme for the management of disabling health crises in older patients: comparison with bed-based Intermediate Care.

PMID: 28655169
Journal: AGE AND AGEING
Year: 2017
Reference: Age Ageing. 2017 Nov 1;46(6):925-931. doi: 10.1093/ageing/afx099.
Impact factor: 4.282
Publication type: Paper in international publication
Authors: Santaeugenia, Sebastia J, Miralles, Ramon, Sabate, Sergi, Inzitari, Marco, Mas, Miquel A et al.
DOI: 10.1093/ageing/afx099

[Do you measure gait speed in your daily clinical practice? A review].

PMID: 26908071
Journal: Revista espanola de geriatria y gerontologia
Year: 2017
Reference: Rev Esp Geriatr Gerontol. 2017 Jan - Feb;52(1):35-43. doi: 10.1016/j.regg.2015.12.010. Epub 2016 Feb 20.
Impact factor: 0
Publication type: Review in national publication
Authors: Inzitari, Marco, Calle, Alicia, Esteve, Anna, Casas, Alvaro, Torrents, Nuria, Martinez, Nicolas et al.
DOI: 10.1016/j.regg.2015.12.010

Hospital-at-home Integrated Care Program for Older Patients With Orthopedic Processes: An Efficient Alternative to Usual Hospital-Based Care.

PMID: 28578883
Journal: Journal of the American Medical Directors Association
Year: 2017
Reference: J Am Med Dir Assoc. 2017 Sep 1;18(9):780-784. doi: 10.1016/j.jamda.2017.04.006. Epub 2017 May 31.
Impact factor: 5.775
Publication type: Paper in international publication
Authors: Closa, Conxita, Mas, Miquel A, Santaeugenia, Sebastia J, Inzitari, Marco, Ribera, Aida, Gallofre, Miquel et al.
DOI: 10.1016/j.jamda.2017.04.006

"Move on Against Frailty": Time to Raise Awareness about Frailty and Prevention of Disability in the Community.

PMID: 27883165
Journal: The Journal of frailty & aging
Year: 2016
Reference: J Frailty Aging. 2016;5(4):201-203. doi: 10.14283/jfa.2016.114.
Impact factor: 0
Publication type: Paper in international publication
Authors: Inzitari, M, Ruiz, D, Martos, J, Santaeugenia, S et al.
DOI: 10.14283/jfa.2016.114

Blog

News

It is part of the PROFIT Project (Personalizing the Approach to Frail Oncology Patients through Assessment and Individualized Intervention), an innovative initiative focused on providing comprehensive care for oncology patients experiencing frailty.

The two centres call on people with a diagnosis of cancer over 65-years-old and living in Barcelona to participate in the trial.

The Barcelona Aging coLLaboratory (BALL) aims to create innovative solutions, with the participation of end users, to improve quality of life and health and social care for the elderly.