About the VHIR
Here at the Vall d'Hebron Research Institute (VHIR) we promote biomedical research, innovation and teaching. Over 1,800 people are seeking to understand diseases today so the treatment can be improved tomorrow.
Research
We are working to understand diseases, to find out how they operate and to create better treatments for patients. Get to know about our groups and their lines of research.
People
People are the centre of the Vall d'Hebron Research Institute (VHIR). This is why we are bound by the principles of freedom of research, gender equality and professional attitudes that HRS4R promotes.
Clinical trials
Our work is not just basic or translational; we are leaders in clinical research. Enter and find about the clinical trials we are conducting and why we are a world reference in this field.
Progress
Our aim is to make the research carried out at the Vall d’Hebron Research Institute (VHIR) a driving force for transformation. How? By identifying new channels and solutions for the promotion of people's health and well-being.
Core facilities
We offer specialist support for researchers, internal and external alike, ranging from specific services to preparing complete projects. All this, from a perspective of quality and speed of response.
News
We offer you a gateway for staying up to date on everything going on at the Vall d’Hebron Research Institute (VHIR), from the latest news to future solidarity activities and initiatives that we are organising.
The main objectives are to improve the diagnosis of immunodeficiencies and autoimmune diseases, addressing also their heterogeneity and mechanisms in close collaboration with the pediatrics, thyroid and systemic disease groups, being internationally recognized in both areas. The group participates in numerous research projects at the Vall d'Hebron Barcelona Hospital Campus that use immunological tests developed for specific projects led by the kidney transplantation, intensive care medicine, internal medicine, allergy and rheumatology groups. During the COVID pandemic the group made contributions in improving the immunogenetic and immunological risk profiles and in the evaluation of the immune response to vaccination and natural infection, collaborating with national and international networks. The group has also generated a biobank of more than 8.000 samples from patients with COVID-19 that have been incorporated into the VHIR biobank.
The group works as a coordinator of the "Focis" Center of Excellence (Federation of Clinical Immunology Societies) of Barcelona.
Determinants of severity in COVID-19 are still poorly understood but are suspected to be predominantly host factors. Besides age, sex and previous comorbidities, we investigate two other general host factors:
1-Genetic variants causing life-threatening COVID-19: We are mostly focused in genetics of immune system. This research line is under the COVIDHGE consortium.
2-The state of the immune system seems to be an important factor but the immunotypes of risk have not yet been clearly defined. The aim of this line of research is to identify the immune mechanisms that determine the severity of SARS-CoV-2 infection in order to propose and validate biomarkers of prognosis and therapeutic requirements.
IP: Manuel Hernández González, Roger Colobran Oriol, Romina Dieli Crimi, Mónica Martínez Gallo
1.1 Analysis of central tolerance (thymic) to thyrotropin receptor in Graves' disease.
1.2 Biomarkers of therapeutic response to in Graves' disease
1.3. Explore the use of system biology tools for the identification of new biomarkers in autoimmune diseases
This line is being developed in collaboration with the Endocrinology and Pediatric Heart Surgery groups of HUVH and also with Endocrinology group of Hospital Universitari Germans Trias i Pujol.
IP: Roger Colobran Oriol
Our group is focused in the cellular and molecular mechanisms of primary immunodeficiencies (PIDs). Our specific projects include:
1-Expanding the genetic and molecular basis of Primary Immunodeficiencies using high-throughput Technologies.
2-Cellular and molecular basis of hemophagocytic lymphohistiocytosis (HLH).
3-Cellular and molecular basis of common variable immunodeficiency (CVID).
PI: Dr. Roger Colobran
PI: Dr. Mónica Martínez-Gallo
PI: Dr. Clara Franco-Jarava
This line is developed in collaboration with the group of "Infection in the immunocompromised pediatric patient" (Head: Dr. Pere Soler-Palacín).
IP: Mónica Martínez Gallo, Manuel Hernández González, Roger Colobran Oriol
IP: Eva Baldrich Rubio Collaborators: Romina Dieli Crimi, Cristina Andrés Vergés Funding agency: Ministerio de Ciencia e Innovación-MICINN Funding: 141875 Reference: PID2023-148950OB-C22 Duration: 01/09/2024 - 31/12/2027
IP: Pere Soler Palacín Collaborators: Laura Batlle Masó, Maria Cristina Díaz de Heredia Rubio, Roger Colobran Oriol, Thaïs Murciano Carrillo, Constantino Sábado Álvarez, Miriam Gonzalez Amores, Janire Perurena Prieto, Andrea Martín Nalda, Lucas Moreno Martín-Retortillo, Jacques Gabriel Rivière Funding agency: Instituto de Salud Carlos III Funding: 179993.75 Reference: AC23_2/00033 Duration: 01/01/2024 - 31/12/2026
IP: Roger Colobran Oriol Collaborators: Romina Dieli Crimi, Aina Aguiló Cucurull, Laura Batlle Masó, Andrea Martín Nalda, Neus Castells Sarret Funding agency: Instituto de Salud Carlos III Funding: 208750 Reference: PI23/00161 Duration: 01/01/2024 - 31/12/2026
IP: Concepció Jacobs Cachá Collaborators: Manuel Hernández González, Natalia Ramos Terrades, Joana Sellarés Roig, Carmen Llorens Cebriá, Janire Perurena Prieto Funding agency: Sociedad Española de Nefrología (S.E.N.) Funding: 24000 Reference: SENEFRO/PROJECTES/2023/JACOBS Duration: 23/12/2023 - 22/12/2025
PMID: 38194689 Journal: BLOOD Year: 2024 Reference: Blood. 2024 Jan 9:blood.2023022098. doi: 10.1182/blood.2023022098. Impact factor: Publication type: Paper in international publication Authors: Abbott, Jordan; Abers, Michael S; Abolhassani, Hassan; Barlogis, Vincent; Barmettler, Sara; Campbell, Nicholas; Chapdelaine, Hugo; Church, Joseph A; Cros, Guilhem; Deordieva, Ekaterina et al. DOI: 10.1182/blood.2023022098
PMID: 36906815 Journal: ACTA OBSTETRICIA ET GYNECOLOGICA SCANDINAVICA Year: 2023 Reference: Acta Obstet Gynecol Scand. 2023 Apr;102(4):480-485. doi: 10.1111/aogs.14524. Impact factor: Publication type: Paper in international publication Authors: Arevalo, Silvia; Aviles, Maria Teresa; Carreras, Elena; Del Barco, Ester; Del Barco, Ester; Franco-Jarava, Clara; Goya, Maria; Hernandez-Gonzalez, Manuel; Maiz, Nerea; Mendoza, Manel et al. DOI: 10.1111/aogs.14524
PMID: 37020259 Journal: Genome Medicine Year: 2023 Reference: Genome Med. 2023 Apr 5;15(1):22. doi: 10.1186/s13073-023-01173-8. Impact factor: Publication type: Paper in international publication Authors: Abad, Jorge; Abad, Sebastien; Abassi, Radhiya; Abdelhadi, Nour Mekki; Abdellaoui, Abdelrafie; Abdelmalek, Abdelkrim; Abdoul, Hendy; Abel, Laurent; Abel, Laurent; Abel, Laurent et al. DOI: 10.1186/s13073-023-01173-8
PMID: 37019466 Journal: ARCHIVES OF DISEASE IN CHILDHOOD Year: 2023 Reference: Arch Dis Child. 2023 Jun;108(6):445-450. doi: 10.1136/archdischild-2022-325281. Epub 2023 Apr 4. Impact factor: Publication type: Paper in international publication Authors: Cabrerizo, Maria; Castano, Anton; Castellarnau, Ester; de la Torre, Maria Jose; Del Rio, Patricia; Fernandez, Jose Luis; Garrido, Estibaliz; Gil, Elena; Hernandez, Maria; Martinez, Javier et al. DOI: 10.1136/archdischild-2022-325281
PMID: 37046475 Journal: Diagnostics Year: 2023 Reference: Diagnostics (Basel). 2023 Mar 27;13(7):1257. doi: 10.3390/diagnostics13071257. Impact factor: Publication type: Review in international publication Authors: Bentow, Chelsea; Beretta, Lorenzo; Callejas-Moraga, Eduardo; Fonollosa-Pla, Vicent; Fritzler, Marvin J; Guillen-Del-Castillo, Alfredo; Mahler, Michael; Marin, Ana; Palterer, Boaz; Perurena-Prieto, Janire et al. DOI: 10.3390/diagnostics13071257
PMID: 35999826 Journal: Medicina clinica (English ed.) Year: 2022 Reference: Med Clin (Engl Ed). 2022 Aug 12;159(3):116-123. doi: 10.1016/j.medcle.2021.09.028. Epub 2022 Aug 19. Impact factor: Publication type: Paper in international publication Authors: Anton, Andres; Arrese-Munoz, Iria; Cardona, Victoria; Esperalba, Juliana; Fernandez-Naval, Candela; Hernandez-Gonzalez, Manuel; Labrador-Horrillo, Moises; Martinez-Gallo, Monica; Pujol-Borrell, Ricardo; Pumarola, Tomas et al. DOI: 10.1016/j.medcle.2021.09.028
PMID: 35105687 Journal: Neurology-Neuroimmunology & Neuroinflammation Year: 2022 Reference: Neurol Neuroimmunol Neuroinflamm. 2022 Feb 1;9(2). pii: 9/2/e1143. doi: 10.1212/NXI.0000000000001143. Print 2022 Mar. Impact factor: 8.485 Publication type: Paper in international publication Authors: Arrambide, Georgina; Zabalza, Ana; Nos, Carlos; Sastre-Garriga, Jaume; Tintore, Mar; Montalban, Xavier; Comabella, Manuel; Espejo, Carmen; Castillo, Joaquin; Otero-Romero, Susana et al. DOI: 10.1212/NXI.0000000000001143
PMID: 35255492 Journal: NATURE Year: 2022 Reference: Nature. 2022 Jul;607(7917):97-103. doi: 10.1038/s41586-022-04576-6. Epub 2022 Mar 7. Impact factor: 49.962 Publication type: Paper in international publication Authors: Tsinaslanidis, George; Birkinshaw, Isobel; Carter, Joseph; Howard, Kate; Ingham, Joanne; Joy, Rosie; Pearson, Harriet; Roche, Samantha; Scott, Zoe; Bancroft, Hollie et al. DOI: 10.1038/s41586-022-04576-6
PMID: 35770252 Journal: EClinicalMedicine Year: 2022 Reference: EClinicalMedicine. 2022 Jun 25;50:101515. doi: 10.1016/j.eclinm.2022.101515. eCollection 2022 Aug. Impact factor: 0 Publication type: Paper in international publication Authors: Davalos, Veronica; Garcia-Prieto, Carlos A; Alegria, Iosune; Aguilera-Albesa, Sergio; Valencia-Ramos, Juan; Rodriguez-Palmero, Agusti; Ruiz, Montserrat; Planas-Serra, Laura; Jordan, Iolanda; Ferrer, Gerardo et al. DOI: 10.1016/j.eclinm.2022.101515
PMID: 35083241 Journal: Frontiers in Medicine Year: 2021 Reference: Front Med (Lausanne). 2022 Jan 10;8:779038. doi: 10.3389/fmed.2021.779038. eCollection 2021. Impact factor: 5.093 Publication type: Paper in international publication Authors: Palmada, Clara, Paola Plata-Menchaca, Erika, Franco-Jarava, Clara, Perez-Carrasco, Marcos, Hernandez-Gonzalez, Manuel, Ferrer, Ricard, Ruiz-Sanmartin, Adolf, Chiscano-Camon, Luis, Ruiz-Rodriguez, Juan Carlos et al. DOI: 10.3389/fmed.2021.779038
PMID: 34943483 Journal: Diagnostics Year: 2021 Reference: Diagnostics (Basel). 2021 Nov 30;11(12). pii: diagnostics11122246. doi: 10.3390/diagnostics11122246. Impact factor: 3.706 Publication type: Paper in international publication Authors: Mahler, Michael, Malyavantham, Kishore, Seaman, Andrea, Bentow, Chelsea, Anunciacion-Llunell, Ariadna, Sanz-Martinez, Maria Teresa, Vinas-Gimenez, Laura, Selva-O'Callaghan, Albert et al. DOI: 10.3390/diagnostics11122246
PMID: 34919042 Journal: CLINICAL AND EXPERIMENTAL RHEUMATOLOGY Year: 2021 Reference: Clin Exp Rheumatol. 2021 Nov-Dec;39 Suppl 133(6):131-139. Epub 2021 Dec 15. Impact factor: 4.473 Publication type: Paper in international publication Authors: Loureiro-Amigo, Jose, Franco-Jarava, Clara, Perurena-Prieto, Janire, Palacio, Carlos, Martinez-Valle, Fernando, Solans-Laque, Roser et al. DOI:
PMID: 34140949 Journal: Frontiers in Immunology Year: 2021 Reference: Front Immunol. 2021 Jun 1;12:665824. doi: 10.3389/fimmu.2021.665824. eCollection 2021. Impact factor: 7.561 Publication type: Letter or abstract Authors: Ruiz-Rodriguez, Juan Carlos, Chiscano-Camon, Luis, Palmada, Clara, Ruiz-Sanmartin, Adolf, Garcia-de-Acilu, Marina, Plata-Menchaca, Erika, Perurena-Prieto, Janire, Hernandez-Gonzalez, Manuel, Perez-Carrasco, Marcos, Soler-Palacin, Pere et al. DOI: 10.3389/fimmu.2021.665824
PMID: 33328136 Journal: Year: 2020 Reference: Arch Bronconeumol (Engl Ed). 2020 Nov 9:S0300-2896(20)30397-5. doi: 10.1016/j.arbres.2020.10.014. Impact factor: Publication type: Other (letters to the editor, abstracts, corrigendum, etc.) Authors: Alvarez, Antoni; Assante, Giulio; Chang-Macchiu, Patricia; Clofent Alarcon, David; Martinez-Gallo, Monica; Polverino, Eva; Romero Mesones, Christian Eduardo; Traversi, Letizia; Tur-Torres, Jordi et al. DOI: 10.1016/j.arbres.2020.10.014
PMID: 33613568 Journal: Frontiers in Immunology Year: 2020 Reference: Front Immunol. 2021 Feb 1;11:625896. doi: 10.3389/fimmu.2020.625896. eCollection 2020. Impact factor: 5.085 Publication type: Paper in international publication Authors: Mariscal, Anais, Milan, Milena, Baucells, Andres, Martinez, Maria Angeles, Guillen, Andrea Garcia, Trallero-Araguas, Ernesto, Alvarado-Cardenas, Marcelo, Martinez-Martinez, Laura, Alserawan, Leticia, Franco-Leyva, Teresa et al. DOI: 10.3389/fimmu.2020.625896
PMID: 33146036 Journal: CEPHALALGIA Year: 2020 Reference: Cephalalgia. 2020 Nov;40(13):1410-1421. doi: 10.1177/0333102420965157. Impact factor: 4.868 Publication type: Paper in international publication Authors: Caronna, Edoardo, Ballve, Alejandro, Llaurado, Arnau, Gallardo, Victor Jose, Maria Ariton, Diana, Lallana, Sofia, Maza, Samuel Lopez, Gadea, Marta Olive, Quibus, Laura, Restrepo, Juan Luis et al. DOI: 10.1177/0333102420965157
PMID: 32802142 Journal: Immunity & Ageing Year: 2020 Reference: Immun Ageing. 2020 Aug 14;17:22. doi: 10.1186/s12979-020-00194-w. eCollection 2020. Impact factor: 2.804 Publication type: Paper in international publication Authors: Boix, Francisco, Martinez-Caceres, Eva, Hernandez, Manuel, Perurena-Prieto, Janire, Gil, Juana, Cantenys, Sergi, Gonzalez-Martinez, Gema, Martinez-Saavedra, Maria T, Rojo, Ricardo, Marco, Francisco M et al. DOI: 10.1186/s12979-020-00194-w
PMID: 30577994 Journal: REVISTA CLINICA ESPANOLA Year: 2019 Reference: Rev Clin Esp. 2019 Dec;219(9):505-513. doi: 10.1016/j.rce.2018.10.006. Epub 2018 Dec 19. Impact factor: 1.043 Publication type: Review in national publication Authors: Moga Naranjo, E, Hernandez Gonzalez, M, Lopez-Trascasa, M, Villar Guimerans, L M, Mariscal-Rodriguez, A et al. DOI: 10.1016/j.rce.2018.10.006
PMID: 31681265 Journal: Frontiers in Immunology Year: 2019 Reference: Front Immunol. 2019 Oct 1;10:2325. doi: 10.3389/fimmu.2019.02325. eCollection 2019. Impact factor: 4.716 Publication type: Paper in international publication Authors: Rudilla, Francesc, Franco-Jarava, Clara, Martinez-Gallo, Monica, Garcia-Prat, Marina, Martin-Nalda, Andrea, Riviere, Jacques, Aguilo-Cucurull, Aina, Mongay, Laura, Vidal, Francisco, Solanich, Xavier et al. DOI: 10.3389/fimmu.2019.02325
PMID: 31379878 Journal: Frontiers in Immunology Year: 2019 Reference: Front Immunol. 2019 Jul 18;10:1695. doi: 10.3389/fimmu.2019.01695. eCollection 2019. Impact factor: 4.716 Publication type: Paper in international publication Authors: Marin-Sanchez, Ana, Alvarez-Sierra, Daniel, Gonzalez, Oscar, Lucas-Martin, Ana, Selles-Sanchez, Alicia, Rudilla, Francesc, Enrich, Emma, Colobran, Roger, Pujol-Borrell, Ricardo et al. DOI: 10.3389/fimmu.2019.01695
PMID: 31182340 Journal: JOURNAL OF AUTOIMMUNITY Year: 2019 Reference: J Autoimmun. 2019 Sep;103:102285. doi: 10.1016/j.jaut.2019.05.013. Epub 2019 Jun 8. Impact factor: 7.543 Publication type: Paper in international publication Authors: Alvarez-Sierra, Daniel, Marin-Sanchez, Ana, Ruiz-Blazquez, Paloma, de Jesus Gil, Carmen, Gonzalez, Oscar, Casteras, Anna, Costa, Roser Ferrer, Nuciforo, Paolo, Colobran, Roger, Pujol-Borrell, Ricardo et al. DOI: 10.1016/j.jaut.2019.05.013
PMID: 29572183 Journal: CLINICAL IMMUNOLOGY Year: 2018 Reference: Clin Immunol. 2018 Jun;191:44-51. doi: 10.1016/j.clim.2018.03.009. Epub 2018 Mar 20. Impact factor: 3.557 Publication type: Paper in international publication Authors: Soler-Palacin, Pere, Colobran, Roger, Aksentijevich, Ivona, Garcia-Latorre, Laura, Franco-Jarava, Clara, Wang, Hongying, Martin-Nalda, Andrea, Alvarez, de la Sierra Daniel, Garcia-Prat, Marina, Bodet, Domingo et al. DOI: 10.1016/j.clim.2018.03.009
PMID: 30386343 Journal: Frontiers in Immunology Year: 2018 Reference: Front Immunol. 2018 Oct 16;9:2397. doi: 10.3389/fimmu.2018.02397. eCollection 2018. Impact factor: 5.511 Publication type: Paper in international publication Authors: Soler-Palacin, Pere, Garcia-Prat, Marina, Martin-Nalda, Andrea, Franco-Jarava, Clara, Riviere, Jacques G, Plaja, Alberto, Bezdan, Daniela, Bosio, Mattia, Martinez-Gallo, Monica, Ossowski, Stephan et al. DOI: 10.3389/fimmu.2018.02397
PMID: 30396220 Journal: HORMONE AND METABOLIC RESEARCH Year: 2018 Reference: Horm Metab Res. 2018 Dec;50(12):863-870. doi: 10.1055/a-0755-7927. Epub 2018 Nov 5. Impact factor: 2.56 Publication type: Paper in international publication Authors: Pujol-Borrell, Ricardo, Alvarez-Sierra, Daniel, Jaraquemada, Dolores, Marin-Sanchez, Ana, Colobran, Roger et al. DOI: 10.1055/a-0755-7927
PMID: 30063981 Journal: CLINICAL IMMUNOLOGY Year: 2018 Reference: Clin Immunol. 2018 Oct;195:49-58. doi: 10.1016/j.clim.2018.07.015. Epub 2018 Jul 29. Impact factor: 3.557 Publication type: Paper in international publication Authors: Dieli-Crimi, Romina, Martinez-Gallo, Monica, Franco-Jarava, Clara, Antolin, Maria, Blasco, Laura, Paramonov, Ida, Semidey, Maria E, Fernandez, Antoni Alvarez, Velasquez, Julio, Martin-Nalda, Andrea et al. DOI: 10.1016/j.clim.2018.07.015
PMID: 27697500 Journal: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY Year: 2017 Reference: J Allergy Clin Immunol. 2017 Apr;139(4):1282-1292. doi: 10.1016/j.jaci.2016.07.039. Epub 2016 Sep 30. Impact factor: 13.081 Publication type: Paper in international publication Authors: Shcherbina, Anna, Torgerson, Troy R, Cabral-Marques, Otavio, Slatter, Mary, Aghamohammadi, Asghar, Chandra, Sharat, Murguia-Favela, Luis, Bonilla, Francisco A, Kanariou, Maria, Damrongwatanasuk, Rongras et al. DOI: 10.1016/j.jaci.2016.07.039
PMID: 29322678 Journal: International Journal of Rheumatic Diseases Year: 2017 Reference: Int J Rheum Dis. 2017 Nov;20(11):1865-1867. doi: 10.1111/1756-185X.12739. Epub 2015 Sep 10. Impact factor: 2.624 Publication type: Letter or abstract Authors: Hernandez-Gonzalez, Manuel, Solans-Laque, Roser, Bujan-Rivas, Segundo, Vilardell-Tarres, Miquel, Martinez-Valle, Fernando, Fernandez-Codina, Andreu et al. DOI: 10.1111/1756-185X.12739
PMID: 28942469 Journal: JOURNAL OF CLINICAL IMMUNOLOGY Year: 2017 Reference: J Clin Immunol. 2017 Nov;37(8):781-789. doi: 10.1007/s10875-017-0447-x. Epub 2017 Sep 23. Impact factor: 3.253 Publication type: Paper in international publication Authors: Franco-Jarava, Clara, Alvarez de la Campa, Elena, Solanich, Xavier, Morandeira-Rego, Francisco, Mas-Bosch, Virginia, Garcia-Prat, Marina, de la Cruz, Xavier, Martin-Nalda, Andrea, Soler-Palacin, Pere, Hernandez-Gonzalez, Manuel et al. DOI: 10.1007/s10875-017-0447-x
PMID: 28369827 Journal: CLINICAL AND EXPERIMENTAL IMMUNOLOGY Year: 2017 Reference: Clin Exp Immunol. 2017 Aug;189(2):226-231. doi: 10.1111/cei.12967. Epub 2017 Apr 20. Impact factor: 3.41 Publication type: Paper in international publication Authors: Franco-Jarava, Clara, Comas, David, Orren, Ann, Hernandez-Gonzalez, Manuel, Colobran, Roger et al. DOI: 10.1111/cei.12967
PMID: 26033741 Journal: ANALES DE PEDIATRIA Year: 2016 Reference: An Pediatr (Barc). 2016 Feb;84(2):70-8. doi: 10.1016/j.anpedi.2015.04.017. Epub 2015 May 30. Impact factor: 0.833 Publication type: Paper in international publication Authors: Figueras-Nadal, C, Caracseghi, F, Soler-Palacin, P, Cobos-Carrascosa, E, Martin-Nalda, A, Hernandez, M et al. DOI: 10.1016/j.anpedi.2015.04.017
PMID: 27091480 Journal: IMMUNOLOGY LETTERS Year: 2016 Reference: Immunol Lett. 2016 Jun;174:19-22. doi: 10.1016/j.imlet.2016.04.011. Epub 2016 Apr 14. Impact factor: 2.483 Publication type: Paper in international publication Authors: Franco-Jarava, Clara, Colobran, Roger, Mestre-Torres, Jaume, Vargas, Victor, Pujol-Borrell, Ricardo, Hernandez-Gonzalez, Manuel et al. DOI: 10.1016/j.imlet.2016.04.011
PMID: 27026170 Journal: JOURNAL OF CLINICAL IMMUNOLOGY Year: 2016 Reference: J Clin Immunol. 2016 May;36(4):388-96. doi: 10.1007/s10875-016-0275-4. Epub 2016 Mar 30. Impact factor: 3.094 Publication type: Paper in international publication Authors: Colobran, Roger, Franco-Jarava, Clara, Martin-Nalda, Andrea, Baena, Neus, Gabau, Elisabeth, Padilla, Natalia, de la Cruz, Xavier, Pujol-Borrell, Ricardo, Comas, David, Soler-Palacin, Pere et al. DOI: 10.1007/s10875-016-0275-4
PMID: 26492593 Journal: Expert Review of Clinical Immunology Year: 2015 Reference: Expert Rev Clin Immunol. 2015;11(12):1277-9. doi: 10.1586/1744666X.2015.1102632. Epub 2015 Oct 22. Impact factor: 2.484 Publication type: Editorail in international publication Authors: Selva-O'Callaghan, Albert, Alvarado-Cardenas, Marcelo, Marin, Ana, Pinal-Fernandez, Iago et al. DOI: 10.1586/1744666X.2015.1102632
PMID: 25662717 Journal: MEDICINA CLINICA Year: 2015 Reference: Med Clin (Barc). 2015 Nov 6;145(9):399-403. doi: 10.1016/j.medcli.2014.11.017. Epub 2015 Feb 7. Impact factor: 1.417 Publication type: Review in national publication Authors: Lima Ruiz, Joan, Marin Sanchez, Ana, Alvarado Cardenas, Marcelo et al. DOI: 10.1016/j.medcli.2014.11.017
PMID: 26361261 Journal: HORMONE AND METABOLIC RESEARCH Year: 2015 Reference: Horm Metab Res. 2015 Sep;47(10):753-66. doi: 10.1055/s-0035-1559646. Epub 2015 Sep 11. Impact factor: 2.121 Publication type: Paper in international publication Authors: Gimenez-Barcons, M, Marin-Sanchez, A, Colobran, R, Pujol-Borrell, R et al. DOI: 10.1055/s-0035-1559646
PMID: 25801430 Journal: JOURNAL OF IMMUNOLOGY Year: 2015 Reference: J Immunol. 2015 May 1;194(9):4199-206. doi: 10.4049/jimmunol.1500183. Epub 2015 Mar 23. Impact factor: 4.922 Publication type: Paper in international publication Authors: Pujol-Borrell, Ricardo, Lucas-Martin, Ana, Tonacchera, Massimo, Fernandez-Doblas, Joaquin, Gimenez-Barcons, Mireia, Colobran, Roger, Gomez-Pau, Ana, Marin-Sanchez, Ana, Casteras, Anna, Obiols, Gabriel et al. DOI: 10.4049/jimmunol.1500183
PMID: 24833896 Journal: PATIENT PREFER ADHER Year: 2014 Reference: Patient Prefer Adherence. 2014 May 2;8:621-9. doi: 10.2147/PPA.S60771. eCollection 2014. Impact factor: 1.491 Publication type: Paper in international publication Authors: Espanol, Teresa, Prevot, Johan, Drabwell, Jose, Sondhi, Seema, Olding, Laurence et al. DOI: 10.2147/PPA.S60771
PMID: 25566243 Journal: Frontiers in immunology Year: 2014 Reference: Front Immunol. 2014 Dec 15;5:627. doi: 10.3389/fimmu.2014.00627. eCollection 2014. Impact factor: 0 Publication type: Review in international publication Authors: Chapel, Helen, Prevot, Johan, Gaspar, Hubert Bobby, Espanol, Teresa, Bonilla, Francisco A, Solis, Leire, Drabwell, Josina et al. DOI: 10.3389/fimmu.2014.00627
PMID: 24012209 Journal: J ALLERGY CLIN IMMUN Year: 2014 Reference: J Allergy Clin Immunol. 2014 Jan;133(1):172-80.e1-10. doi: 10.1016/j.jaci.2013.06.047. Epub 2013 Sep 5. Impact factor: 11.248 Publication type: Paper in international publication Authors: Marodi, Laszlo, Szaflarska, Anna, Sass, Mareike, Pignata, Claudio, Kilic, Sara Sebnem, Caragol, Isabel, Baumann, Ulrich, Klein, Christoph, Welte, Karl, Hansen, Gesine et al. DOI: 10.1016/j.jaci.2013.06.047
PMID: 24760113 Journal: J CLIN IMMUNOL Year: 2014 Reference: J Clin Immunol. 2014 Jul;34(5):521-3. doi: 10.1007/s10875-014-0042-3. Epub 2014 Apr 24. Impact factor: 2.654 Publication type: Paper in international publication Authors: Guilarte, Mar, Hernandez-Gonzalez, Manuel, Colobran, Roger, Pujol-Borrell, Ricardo et al. DOI: 10.1007/s10875-014-0042-3
PMID: 23480186 Journal: CLINICAL AND EXPERIMENTAL IMMUNOLOGY Year: 2013 Reference: Clin Exp Immunol. 2013 Apr;172(1):63-72. doi: 10.1111/cei.12039. Impact factor: 3.409 Publication type: Paper in international publication Authors: Vidaller, A, Wong, G K, Goldacker, S, Winterhalter, C, Grimbacher, B, Chapel, H, Lucas, M, Alecsandru, D, McEwen, D, Quinti, I et al. DOI: 10.1111/cei.12039
PMID: 22531327 Journal: NATURE REVIEWS IMMUNOLOGY Year: 2012 Reference: Nat Rev Immunol. 2012 Apr 25;12(5):396; author reply 396. doi: 10.1038/nri3158-c1. Impact factor: 33.287 Publication type: Letter whit IF Authors: Pachon, Gisela, Caragol, Isabel, Petriz, Jordi et al. DOI: 10.1038/nri3158-c1
PMID: 22533245 Journal: JOURNAL OF INVESTIGATIONAL ALLERGOLOGY AND CLINICAL IMMUNOLOGY Year: 2012 Reference: J Investig Allergol Clin Immunol. 2012;22(2):149-52. Impact factor: 2.269 Publication type: Editorail in international publication Authors: Garces, P, Garcia-Martin, F, Detkova, D, Espanol, T et al. DOI:
PMID: 21168377 Journal: ANALES DE PEDIATRIA Year: 2011 Reference: An Pediatr (Barc). 2011 Feb;74(2):74-83. Epub 2010 Dec 17. Impact factor: 0.57 Publication type: Paper in national publication Authors: Martin-Nalda, A, Soler-Palacin, P, Espanol Boren, T, Caragol Urgelles, I, Diaz de Heredia Rubio, C, Figueras Nadal, C et al. DOI: 10.1016/j.anpedi.2010.09.019
PMID: 21057261 Journal: MEDICINE Year: 2010 Reference: Medicine (Baltimore). 2010 Nov;89(6):381-402. Impact factor: 5.054 Publication type: Paper in international publication Authors: , , , , , , , , , et al. DOI: 10.1097/MD.0b013e3181fdd832
PMID: 20638349 Journal: ANALES DE PEDIATRIA Year: 2010 Reference: An Pediatr (Barc). 2010 Dec;73(6):362.e1-8. Epub 2010 Jul 17. Impact factor: 0.363 Publication type: Review in national publication Authors: , , , , , , , et al. DOI: 10.1016/j.anpedi.2010.04.016
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PMID: 20173115 Journal: BLOOD Year: 2010 Reference: Blood. 2010 Apr 22;115(16):3231-8. Epub 2010 Feb 19. Impact factor: 10.555 Publication type: Paper in international publication Authors: , , , , , , , , , et al. DOI: 10.1182/blood-2009-09-239087
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PhD student: Ana María Marín Sánchez, Ana María Marín Sánchez Director/s: Ricardo Pujol Borrell, Roger Colobran Oriol University: Universidad Autònoma de Barcelona Year: 2020
PhD student: Laura Viñas Gimenez, Laura Viñas Gimenez Director/s: Mónica Martínez Gallo, Juan Sayos Ortega University: Universidad Autònoma de Barcelona Year: 2019
PhD student: Clara Franco Jarava Director/s: Roger Colobran Oriol, Manuel Hernández González University: Universidad Autònoma de Barcelona Year: 2017
PhD student: Paula Andrea Correa Vanegas Director/s: Ricardo Pujol Borrell, Roger Colobran Oriol University: Universidad Autònoma de Barcelona Year: 2013
The new technology allows more sensitive detection of scleroderma patients' autoantibodies, which are related to the severity and progression of the disease.
A study from the Vall d’Hebron Campus demonstrates that the Ex Vivo C5b-9 deposition test is useful for monitoring the activity of the complement system (CS) in patients with aHUS or transplant-associated TMA.
The results show that, in some patients with mutations in the X chromosome, the healthy gene is inactivated and the mutated gene manifests itself, which favors the onset of the disease.
