Physiology and Pathophysiology of the Digestive Tract

The group of Physiology and Pathophysiology of the Digestive Tract focuses its research activity on the functioning of the digestive tract as a whole, including the functions of secretion, motility, absorption and barrier both in healthy individuals and in the presence of disease. The application of knowledge to clinical practice is a priority for the group.

Research in digestive motility encompasses disorders of visceral sensitivity, the brain-gut axis and intestinal allergy. Research on inflammation also includes the pancreas.

We have also launched a cross-sectional research program that focuses on the role of the gut microbiota in inflammation and gut function.

Team

Méndez Soriano, Sara

Physiology and Pathophysiology of the Digestive Tract
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Oscar José Hernández Cristancho

Predoctoral researcher
Physiology and Pathophysiology of the Digestive Tract
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Raquel Ibañez Ferrer

Research technician
Physiology and Pathophysiology of the Digestive Tract
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Raul Velamazan Sandalinas

Predoctoral researcher
Physiology and Pathophysiology of the Digestive Tract
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Rodríguez López, Ana María

Physiology and Pathophysiology of the Digestive Tract
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Teodora Pribic

Postdoctoral researcher
Physiology and Pathophysiology of the Digestive Tract
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Méndez Soriano, Sara

Physiology and Pathophysiology of the Digestive Tract
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Oscar José Hernández Cristancho

Predoctoral researcher
Physiology and Pathophysiology of the Digestive Tract
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Raquel Ibañez Ferrer

Research technician
Physiology and Pathophysiology of the Digestive Tract
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Raul Velamazan Sandalinas

Predoctoral researcher
Physiology and Pathophysiology of the Digestive Tract
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Rodríguez López, Ana María

Physiology and Pathophysiology of the Digestive Tract
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Teodora Pribic

Postdoctoral researcher
Physiology and Pathophysiology of the Digestive Tract
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Projects

Contribución de la disfunción de CFTR al desarrollo y agresividad del cáncer de páncreas. Estimulación del crecimiento tumoral y metástasis por células estrelladas carentes de CFTR.

IP: -
Collaborators: Laura Campderros Traver, Eva Polverino
Funding agency: Instituto de Salud Carlos III
Funding: 147620
Reference: PI22/00887
Duration: 01/01/2023 - 31/12/2025

Development, dIagnostic and prevention of gender-related Somatic and mental COmorbitiEs in IRritable bowel syndrome In Europe (DISCOvERIE)

IP: Fco Javier Santos Vicente
Collaborators: Beatriz Lobo Alvarez, Silvia Muñoz Caller, Carmen Alonso Cotoner, Ana Maria Gonzalez Castro, Elba Exposito Fernandez, Marc Pigrau Pastor, Development, dIagnostic and prevention of gender-related Somatic and mental COmorbitiEs in IRritable bowel syndrome In Europe (D, Adoración Nieto Ruiz, Alejandro Henao Paez, Consuelo Cammarota, José Alegre Martin, Jesus Castro Marrero, Marta Ribases Haro, Natalia Llonga Tejedor, Amanda Rodríguez Urrutia
Funding agency: EUROPEAN COMMISSION
Funding: 1148684.84
Reference: DISCOVERIE_H2020-SC1-BHC2019
Duration: 01/01/2020 - 31/05/2025

H2O Health Outcomes Observatory

IP: Yolima Cossio Gil
Collaborators: Cristina Hernández Pascual, Natalia Borruel Sainz, H2O Health Outcomes Observatory, Gemma Galán Martinez, Monica Sanchez Bartres, Marta Ferri Peradalta
Funding agency: The Innovative Medicines Initiative
Funding: 1097257.5
Reference: H2O_IMI2-2020
Duration: 01/10/2020 - 30/09/2025

Publications

Clinical and molecular study of patients with thyroid dyshormogenesis and variants in the thyroglobulin gene.

PMID: 39040671
Journal: Frontiers in Endocrinology
Year: 2024
Reference: Front Endocrinol (Lausanne). 2024 Jul 8;15:1367808. doi: 10.3389/fendo.2024.1367808. eCollection 2024.
Impact factor:
Publication type: Paper in international publication
Authors: Antolin, Maria; Baz-Redon, Noelia; Camats-Tarruella, Nuria; Campos-Martorell, Ariadna; Clemente, Maria; Comas-Armangue, Gemma; Fernandez-Cancio, Monica; Garcia-Arumi, Elena; Gonzalez-Llorens, Nuria; Leno-Colorado, Jordi et al.
DOI: 10.3389/fendo.2024.1367808

Performance of Massive Parallel Sequencing-Based Cell-Free DNA Testing in Compromised Pregnancies.

PMID: 39064047
Journal: Journal of Clinical Medicine
Year: 2024
Reference: J Clin Med. 2024 Jul 9;13(14):4007. doi: 10.3390/jcm13144007.
Impact factor:
Publication type: Paper in international publication
Authors: Antolin, Maria; Carreras, Elena; Castells, Neus; Garcia-Arumi, Elena; Martinez-Cruz, Desiree; Plaja, Alberto; Sanchez, Maria Angeles; Tarraso, Guillermo; Tizzano, Eduardo F; Xuncla, Mar et al.
DOI: 10.3390/jcm13144007

Microscopic Colitis and Celiac Disease: Sharing More than a Diagnostic Overlap.

PMID: 39064676
Journal: Nutrients
Year: 2024
Reference: Nutrients. 2024 Jul 11;16(14):2233. doi: 10.3390/nu16142233.
Impact factor:
Publication type: Paper in international publication
Authors: Exposito, Elba; Farago-Perez, Georgina; Fernandez-Banares, Fernando; Gonzalez-Castro, Ana Maria; Guagnozzi, Danila; Ortega-Barrionuevo, Jonathan; Zabana, Yamile et al.
DOI: 10.3390/nu16142233

Patients with Thyroid Dyshormonogenesis and DUOX2 Variants: Molecular and Clinical Description and Genotype-Phenotype Correlation.

PMID: 39126042
Journal:
Year: 2024
Reference: Int J Mol Sci. 2024 Aug 3;25(15):8473. doi: 10.3390/ijms25158473.
Impact factor:
Publication type: Paper in international publication
Authors: Aguilar-Riera, Cristina; Antolin, Maria; Baz-Redon, Noelia; Camats-Tarruella, Nuria; Campos, Ariadna; Clemente, Maria; Fernandez-Cancio, Monica; Garcia-Arumi, Elena; Gonzalez-Llorens, Nuria; Mogas, Eduard et al.
DOI: 10.3390/ijms25158473

Prevalence of non-celiac gluten sensitivity and assessment of the response to gluten-free diet in a cohort of patients with fibromyalgia.

PMID: 35900154
Journal: RHEUMATOLOGY
Year: 2023
Reference: Rheumatology (Oxford). 2023 Mar 1;62(3):1069-1077. doi: 10.1093/rheumatology/keac434.
Impact factor:
Publication type: Paper in international publication
Authors: Almirall, Miriam; Casellas, Francesc; de Torres, Ines; Dot, Joan; Marsal S, Sara; Segurola, Hegoi et al.
DOI: 10.1093/rheumatology/keac434

Underlying etiology associated with the diagnosis of absent contractility on high resolution esophageal manometry.

PMID: 35278504
Journal: Gastroenterologia y Hepatologia
Year: 2023
Reference: Gastroenterol Hepatol. 2023 Jan;46(1):10-16. doi: 10.1016/j.gastrohep.2022.03.003. Epub 2022 Mar 9.
Impact factor:
Publication type: Paper in national publication
Authors: Alcala-Gonzalez, Luis Gerardo; Barba-Orozco, Elizabeth; Barber-Caselles, Claudia; Jimenez-Masip, Alba; Relea-Perez, Lucia et al.
DOI: 10.1016/j.gastrohep.2022.03.003

The Stressed Gut: Region-specific Immune and Neuroplasticity Changes in Response to Chronic Psychosocial Stress.

PMID: 36606438
Journal: Journal of Neurogastroenterology and Motility
Year: 2023
Reference: J Neurogastroenterol Motil. 2023 Jan 30;29(1):72-84. doi: 10.5056/jnm22009.
Impact factor:
Publication type: Paper in international publication
Authors: Beltran, Caroll; Clarke, Gerard; Cryan, John F; Dinan, Timothy G; Finger, Beate-C; Hyland, Niall P; Lobo, Beatriz; Lomasney, Kevin W; Santos, Javier; Tramullas, Monica et al.
DOI: 10.5056/jnm22009

mTOR inhibitors a potential predisposing factor for chronic hepatitis E: Results from the prospective collaborative CHES Study (Chronic Hepatitis E Screening in patients with immune impairment and increased transaminases levels)

PMID: 36731726
Journal: Gastroenterologia y Hepatologia
Year: 2023
Reference: Gastroenterol Hepatol. 2023 Dec;46(10):764-773. doi: 10.1016/j.gastrohep.2023.01.010. Epub 2023 Jan 31.
Impact factor:
Publication type: Paper in national publication
Authors: Alonso, Virginia Robles; Barciela, Mar Riveiro; Berastegui, Cristina; Bilbao, Itxarone; Buti, Maria; Camprecios, Joan Martinez; Castells, Lluis; Cots, Meritxell Ventura; Diez, Basilio Rodriguez; Eliz, Maria Garcia et al.
DOI: 10.1016/j.gastrohep.2023.01.010

Effect of intracolonic volume on gastric sensory-motor responses in constipation-predominant irritable bowel syndrome.

PMID: 35861576
Journal: NEUROGASTROENTEROLOGY AND MOTILITY
Year: 2022
Reference: Neurogastroenterol Motil. 2022 Dec;34(12):e14433. doi: 10.1111/nmo.14433. Epub 2022 Jul 21.
Impact factor:
Publication type: Paper in international publication
Authors: Caballero, Noemi; Leal, Carles; Marin, Ingrid; Riu, Fausto; Serra, Jordi et al.
DOI: 10.1111/nmo.14433

Co Treatment With Biologic Agents and Immunotherapy in the Setting of irAEs of Difficult Management.

PMID: 35847803
Journal: Frontiers in Medicine
Year: 2022
Reference: Front Med (Lausanne). 2022 Jun 30;9:906098. doi: 10.3389/fmed.2022.906098. eCollection 2022.
Impact factor:
Publication type: Review in international publication
Authors: Borruel, Natalia; Martinez-Valle, Fernando; Robles-Alonso, Virginia et al.
DOI: 10.3389/fmed.2022.906098

Nutritional challenges in patients with gastroparesis.

PMID: 35838300
Journal: CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE
Year: 2022
Reference: Curr Opin Clin Nutr Metab Care. 2022 Sep 1;25(5):360-363. doi: 10.1097/MCO.0000000000000856. Epub 2022 Jul 16.
Impact factor:
Publication type: Paper in international publication
Authors: Aguilar, Ariadna; Malagelada, Carolina; Serra, Jordi et al.
DOI: 10.1097/MCO.0000000000000856

Mucosal Plasma Cell Activation and Proximity to Nerve Fibres Are Associated with Glycocalyx Reduction in Diarrhoea-Predominant Irritable Bowel Syndrome: Jejunal Barrier Alterations Underlying Clinical Manifestations.

PMID: 35805133
Journal: Cells
Year: 2022
Reference: Cells. 2022 Jun 28;11(13). pii: cells11132046. doi: 10.3390/cells11132046.
Impact factor:
Publication type: Paper in international publication
Authors: Albert-Bayo, Merce; Alonso-Cotoner, Carmen; Azpiroz, Fernando; Exposito, Elba; Fortea, Marina; Ganda Mall, John-Peter; Gonzalez-Castro, Ana M; Guagnozzi, Danila; Lobo, Beatriz; Martinez, Cristina et al.
DOI: 10.3390/cells11132046

Gallbladder disease and pancreatic cancer risk: a multicentric case-control European study.

PMID: 34545020
Journal: EUROPEAN JOURNAL OF CANCER PREVENTION
Year: 2021
Reference: Eur J Cancer Prev. 2021 Nov 1;30(6):423-430. doi: 10.1097/CEJ.0000000000000588.
Impact factor:
Publication type: Paper in international publication
Authors: Balsells, J; Barbera, V M; Carrato, A; Costello, E; Crnogorac-Jurcevic, T; Dominguez-Munoz, E; Farre, A; Gomez-Rubio, P; Greenhalf, W; Gress, T et al.
DOI: 10.1097/CEJ.0000000000000588

Does Day-to-Day Variability in Stool Consistency Link to the Fecal Microbiota Composition?

PMID: 34458156
Journal: Frontiers in Cellular and Infection Microbiology
Year: 2021
Reference: Front Cell Infect Microbiol. 2021 Jul 20;11:639667. doi: 10.3389/fcimb.2021.639667. eCollection 2021.
Impact factor:
Publication type: Paper in international publication
Authors: Bojic, Svetlana; de Vos, Willem M; Jalanka, Jonna; Jonkers, Daisy M A E; Manichanh, Chaysavanh; Masclee, Ad A M; Penders, John; Pozuelo, Marta; Rajilic-Stojanovic, Mirjana; Salonen, Anne et al.
DOI: 10.3389/fcimb.2021.639667

Differential Effects of Western and Mediterranean-Type Diets on Gut Microbiota: A Metagenomics and Metabolomics Approach.

PMID: 34444797
Journal: Nutrients
Year: 2021
Reference: Nutrients. 2021 Jul 30;13(8). pii: nu13082638. doi: 10.3390/nu13082638.
Impact factor:
Publication type: Paper in international publication
Authors: Azpiroz, Fernando; Barber, Claudia; Bendezu, Rogger Alvaro; Espin, Juan Carlos; Guarner, Francisco; Margolles, Abelardo; Masihy, Marcela; Mego, Marianela; Sabater, Carlos; Vallejo, Fernando et al.
DOI: 10.3390/nu13082638

A Cross-Sectional Survey on Professionals to Assess Health Needs of Newly Arrived Migrants in Spain.

PMID: 34409005
Journal: Frontiers in Public Health
Year: 2021
Reference: Front Public Health. 2021 Aug 2;9:667251. doi: 10.3389/fpubh.2021.667251. eCollection 2021.
Impact factor:
Publication type: Paper in international publication
Authors: Denial, Abdallah; Esteban, Esperanza; Evangelidou, Stella; Hajdok, Eva; Moreno, Ruben; Murias-Closas, Adria; Oliveira, Ines; Serre-Delcor, Nuria; Trevino, Begona et al.
DOI: 10.3389/fpubh.2021.667251

Consensus document on the management preferences of patients with ulcerative colitis: points to consider and recommendations.

PMID: 32804838
Journal: EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY
Year: 2020
Reference: Eur J Gastroenterol Hepatol. 2020 Dec;32(12):1514-1522. doi: 10.1097/MEG.0000000000001885.
Impact factor:
Publication type: Paper in international publication
Authors: Arguelles-Arias, Federico; Barreiro-de Acosta, Manuel; Cabez, Ana; Casellas, Francesc; Garcia-Lopez, Santiago; Gomez, Susana; Gonzalez-Lama, Yago; Guinard Vicens, Daniel; Loza, Estibaliz; Marin Sanchez, Laura et al.
DOI: 10.1097/MEG.0000000000001885

Peripheral Corticotropin-Releasing Factor Triggers Jejunal Mast Cell Activation and Abdominal Pain in Patients With Diarrhea-Predominant Irritable Bowel Syndrome.

PMID: 32740086
Journal: AMERICAN JOURNAL OF GASTROENTEROLOGY
Year: 2020
Reference: Am J Gastroenterol. 2020 Dec;115(12):2047-2059. doi: 10.14309/ajg.0000000000000789.
Impact factor:
Publication type: Paper in international publication
Authors: Alonso-Cotoner, Carmen; Antolin, Maria; Azpiroz, Fernando; de Torres, Ines; Fortea, Marina; Gonzalez-Castro, Ana; Guilarte, Mar; Lobo, Beatriz; Martinez, Cristina; Pardo-Camacho, Cristina et al.
DOI: 10.14309/ajg.0000000000000789

A Global, Prospective, Observational Study Measuring Disease Burden and Suffering in Patients with Ulcerative Colitis Using the Pictorial Representation of Illness and Self-Measure Tool.

PMID: 32722760
Journal: Journal of Crohns & Colitis
Year: 2020
Reference: J Crohns Colitis. 2020 Jul 29;15(2):228-37. doi: 10.1093/ecco-jcc/jjaa159.
Impact factor:
Publication type: Paper in international publication
Authors: Ahmad, Tariq; Ardizzone, Sandro; Casellas, Francesc; Ghosh, Subrata; Gubonina, Irina; Kligys, Kristina; Marquez, Juan R; Petersson, Joel; Peyrin-Biroulet, Laurent; Rioux, Louis-Charles et al.
DOI: 10.1093/ecco-jcc/jjaa159

Early treatment with anti-tumor necrosis factor agents improves long-term effectiveness in symptomatic stricturing Crohn's disease.

PMID: 32723069
Journal: United European Gastroenterology Journal
Year: 2020
Reference: United European Gastroenterol J. 2020 Nov;8(9):1056-1066. doi: 10.1177/2050640620947579. Epub 2020 Jul 28.
Impact factor:
Publication type: Paper in international publication
Authors: Aguirre, Urko; Alfambra, Erika; Aparicio, Juan Carlos; Armesto, Edisa; Arranz, Laura; Arroyo, Maite; Aullo, Carolina; Baston, Iria; Benitez, Jose Manuel; Botella, Belen et al.
DOI: 10.1177/2050640620947579

Development and validation of the QUECOMIICAT questionnaire: a tool to assess disease-related knowledge in patients with inflammatory bowel disease.

PMID: 31317762
Journal: REVISTA ESPANOLA DE ENFERMEDADES DIGESTIVAS
Year: 2019
Reference: Rev Esp Enferm Dig. 2019 Aug;111(8):586-592. doi: 10.17235/reed.2019.6298/2019.
Impact factor:
Publication type: Paper in international publication
Authors: Aldeguer, Xavier; Amil, Paloma; Barber, Claudia; Casellas, Francesc; Espin, Eloy; Gallego, Marta; Garcia-Planella, Esther; Gonzalez-Mestre, Assumpcio; Guardiola, Jordi; Marin, Laura et al.
DOI: 10.17235/reed.2019.6298/2019

Unraveling the effects of the gut microbiota composition and function on horse endurance physiology.

PMID: 31270376
Journal: Scientific Reports
Year: 2019
Reference: Sci Rep. 2019 Jul 3;9(1):9620. doi: 10.1038/s41598-019-46118-7.
Impact factor:
Publication type: Paper in international publication
Authors: Barrey, Eric; Clark, Allison; Esquerre, Diane; Helbling, Jean-Christophe; Mach, Nuria; Moisan, Marie-Pierre; Moyec, Laurence le; Philippe, Catherine; Plancade, Sandra; Robert, Celine et al.
DOI: 10.1038/s41598-019-46118-7

Editorial: the increasing burden of microscopic colitis.

PMID: 31246366
Journal: ALIMENTARY PHARMACOLOGY & THERAPEUTICS
Year: 2019
Reference: Aliment Pharmacol Ther. 2019 Jul;50(2):228-229. doi: 10.1111/apt.15363.
Impact factor:
Publication type: Editorail in international publication
Authors: Guagnozzi, Danila; Pastorelli, Luca; Tontini, Gian Eugenio et al.
DOI: 10.1111/apt.15363

Perioperative management and early complications after intestinal resection with ileocolonic anastomosis in Crohn's disease: analysis from the PRACTICROHN study.

PMID: 31217980
Journal: Gastroenterology Report
Year: 2019
Reference: Gastroenterol Rep (Oxf). 2019 Jun;7(3):168-175. doi: 10.1093/gastro/goz010. Epub 2019 Apr 19.
Impact factor:
Publication type: Paper in international publication
Authors: Barreiro-de Acosta, Manuel; Barrio, Jesus; Borruel Sainz, Natalia; Castro, Manuel; Cea-Calvo, Luis; de Francisco, Ruth; Domenech, Eugeni; Garcia Sanchez, Valle; Gutierrez, Ana; Julia, Berta et al.
DOI: 10.1093/gastro/goz010

Post-infectious IBS: Defining its clinical features and prognosis using an internet-based survey.

PMID: 30288287
Journal: United European Gastroenterology Journal
Year: 2018
Reference: United European Gastroenterol J. 2018 Oct;6(8):1245-1253. doi: 10.1177/2050640618779923. Epub 2018 May 23.
Impact factor:
Publication type: Paper in international publication
Authors: Aziz, Qasim; Azpiroz, Fernando; Barbara, Giovanni; Boeckxstaens, Guy Ee; Card, Tim; Enck, Paul; Marshall, John; Mearin, Fermin; Santos, Javier; Spiller, Robin et al.
DOI: 10.1177/2050640618779923

Increased Pancreatic Protease Activity in Response to Antibiotics Impairs Gut Barrier and Triggers Colitis.

PMID: 30182050
Journal: Cellular and molecular gastroenterology and hepato
Year: 2018
Reference: Cell Mol Gastroenterol Hepatol. 2018 May 29;6(3):370-388.e3. doi: 10.1016/j.jcmgh.2018.05.008. eCollection 2018.
Impact factor:
Publication type: Paper in international publication
Authors: Blesl, Andreas; Clavel, Thomas; Hahne, Hannes; Haller, Dirk; Heinzlmeir, Stephanie; Hormannsperger, Gabriele; Kump, Patrizia; Kuster, Bernhard; Lagkouvardos, Ilias; Ludwig, Christina et al.
DOI: 10.1016/j.jcmgh.2018.05.008

Functional neuromuscular impairment in severe intestinal dysmotility.

PMID: 30178519
Journal: NEUROGASTROENTEROLOGY AND MOTILITY
Year: 2018
Reference: Neurogastroenterol Motil. 2018 Dec;30(12):e13458. doi: 10.1111/nmo.13458. Epub 2018 Sep 3.
Impact factor:
Publication type: Paper in international publication
Authors: Accarino, Anna; Azpiroz, Fernando; De Giorgio, Roberto; Gallego, Diana; Gori, Alessandra; Jimenez, Marcel; Malagelada, Carolina; Malagelada, Juan Ramon et al.
DOI: 10.1111/nmo.13458

Metabolomic signature of the postprandial experience.

PMID: 30101554
Journal: NEUROGASTROENTEROLOGY AND MOTILITY
Year: 2018
Reference: Neurogastroenterol Motil. 2018 Dec;30(12):e13447. doi: 10.1111/nmo.13447. Epub 2018 Aug 13.
Impact factor:
Publication type: Paper in international publication
Authors: Accarino, Anna; Amigo, Nuria; Azpiroz, Fernando; Canellas, Nicolau; Ciccantelli, Barbara; Correig, Xavier; Gomez, Josep; Malagelada, Carolina; Pribic, Teodora et al.
DOI: 10.1111/nmo.13447

Crohn's Disease Disturbs the Immune Properties of Human Adipose-Derived Stem Cells Related to Inflammasome Activation.

PMID: 28966116
Journal: Stem Cell Reports
Year: 2017
Reference: Stem Cell Reports. 2017 Oct 10;9(4):1109-1123. doi: 10.1016/j.stemcr.2017.07.014. Epub 2017 Sep 28.
Impact factor:
Publication type: Paper in international publication
Authors: Borruel, Natalia; Ejarque, Miriam; Espin, Eloy; Fernandez-Veledo, Sonia; Guarner, Francisco; Keiran, Noelia; Madeira, Ana; Marti, Marc; Maymo-Masip, Elsa; Menacho, Margarida et al.
DOI: 10.1016/j.stemcr.2017.07.014

Towards standards for human fecal sample processing in metagenomic studies.

PMID: 28967887
Journal: NATURE BIOTECHNOLOGY
Year: 2017
Reference: Nat Biotechnol. 2017 Nov;35(11):1069-1076. doi: 10.1038/nbt.3960. Epub 2017 Oct 2.
Impact factor:
Publication type: Paper in international publication
Authors: Alberti, Adriana; Allen-Vercoe, Emma; Bertrand, Laurie; Blaut, Michael; Bork, Peer; Brown, Jillian R M; Carton, Thomas; Coelho, Luis Pedro; Cools-Portier, Stephanie; Costea, Paul I et al.
DOI: 10.1038/nbt.3960

Microbiome-Based Diagnostics: Ready for Applications in Laboratory Medicine?

PMID: 28882888
Journal: CLINICAL CHEMISTRY
Year: 2017
Reference: Clin Chem. 2017 Nov;63(11):1674-1679. doi: 10.1373/clinchem.2016.264473. Epub 2017 Sep 7.
Impact factor:
Publication type: Paper in international publication
Authors: Dore, Joel; Guarner, Francisco; Luna, Ruth Ann; Ringel, Yehuda; Versalovic, James et al.
DOI: 10.1373/clinchem.2016.264473

Long-term safety and effectiveness of levodopa-carbidopa intestinal gel infusion.

PMID: 28828219
Journal: Brain and Behavior
Year: 2017
Reference: Brain Behav. 2017 Jul 7;7(8):e00758. doi: 10.1002/brb3.758. eCollection 2017 Aug.
Impact factor:
Publication type: Paper in international publication
Authors: Abu-Suboh, Monder; Alvarez-Sabin, Jose; Armengol, Josep Ramon; De Fabregues, Oriol; Dot, Joan; Ferre, Alex; Gomez, Maria Rosa; Hernandez-Vara, Jorge; Ibarria, Marta; Puiggros, Carolina et al.
DOI: 10.1002/brb3.758

Surgical Trauma Caused by Different Abdominal Access Routes-Comparison of Open Surgical, Laparoscopic, and NOTES Transgastric Techniques in a Porcine Model.

PMID: 27163486
Journal: Journal of Laparoendoscopic & Advanced Surgical Techniques
Year: 2016
Reference: J Laparoendosc Adv Surg Tech A. 2016 Jul;26(7):511-6. doi: 10.1089/lap.2016.0034. Epub 2016 May 10.
Impact factor:
Publication type: Paper in international publication
Authors: Abu-Suboh-Abadia, Monder; Armengol, Jordi; Armengol-Miro, Jose Ramon; Arroyo Vazquez, Jorge; Azadani, Asghar; Bergstrom, Maria; Dot, Joan; Esteves, Marielle; Fonseca, Carla; Masachs, Miquel et al.
DOI: 10.1089/lap.2016.0034

The joint power of sex and stress to modulate brain-gut-microbiota axis and intestinal barrier homeostasis: implications for irritable bowel syndrome.

PMID: 26556786
Journal: NEUROGASTROENTEROLOGY AND MOTILITY
Year: 2016
Reference: Neurogastroenterol Motil. 2016 Apr;28(4):463-86. doi: 10.1111/nmo.12717. Epub 2015 Nov 11.
Impact factor:
Publication type: Paper in international publication
Authors: Alonso-Cotoner, C; Casado-Bedmar, M; Lobo, B; Pigrau, M; Rodino-Janeiro, B K; Santos, J; Vicario, M et al.
DOI: 10.1111/nmo.12717

Galectin-4 interacts with the drug transporter human concentrative nucleoside transporter 3 to regulate its function.

PMID: 26481311
Journal: FASEB JOURNAL
Year: 2016
Reference: FASEB J. 2016 Feb;30(2):544-54. doi: 10.1096/fj.15-272773. Epub 2015 Oct 19.
Impact factor:
Publication type: Paper in international publication
Authors: Antolin, Maria; Casulleras, Olga; Fernandez-Calotti, Paula; Guarner, Francisco; Pastor-Anglada, Marcal et al.
DOI: 10.1096/fj.15-272773

The role of mast cells in functional GI disorders.

PMID: 26194403
Journal: GUT
Year: 2016
Reference: Gut. 2016 Jan;65(1):155-68. doi: 10.1136/gutjnl-2015-309151. Epub 2015 Jul 20.
Impact factor:
Publication type: Paper in international publication
Authors: Santos, Javier; Vicario, Maria; Wouters, Mira M et al.
DOI: 10.1136/gutjnl-2015-309151

Mechanisms of stress-induced visceral pain in irritable bowel syndrome.

PMID: 26383294
Journal: PSYCHONEUROENDOCRINO
Year: 2015
Reference: Psychoneuroendocrinology. 2015 Nov;61:8-9. doi: 10.1016/j.psyneuen.2015.07.410. Epub 2015 Aug 8.
Impact factor:
Publication type: Paper in international publication
Authors: Vicario, Maria et al.
DOI: 10.1016/j.psyneuen.2015.07.410

Predictive value of early restoration of quality of life in Crohn's disease patients receiving antitumor necrosis factor agents.

PMID: 25302652
Journal: J GASTROEN HEPATOL
Year: 2015
Reference: J Gastroenterol Hepatol. 2015 Feb;30(2):286-91. doi: 10.1111/jgh.12803.
Impact factor:
Publication type: Paper in international publication
Authors: Borruel, Natalia; Casellas, Francesc; Herrera-deGuise, Claudia; Navarro, Ester; Robles, Virginia et al.
DOI: 10.1111/jgh.12803

Intestinal gas content and distribution in health and in patients with functional gut symptoms.

PMID: 26095329
Journal: NEUROGASTROENT MOTIL
Year: 2015
Reference: Neurogastroenterol Motil. 2015 Sep;27(9):1249-57. doi: 10.1111/nmo.12618. Epub 2015 Jun 21.
Impact factor:
Publication type: Paper in international publication
Authors: Accarino, A; Azpiroz, F; Barba, E; Bendezu, R A; Burri, E; Cisternas, D; Malagelada, C; Malagelada, J-R; Monclus, E; Navazo, I et al.
DOI: 10.1111/nmo.12618

Digestive, cognitive and hedonic responses to a meal.

PMID: 25557693
Journal: NEUROGASTROENT MOTIL
Year: 2015
Reference: Neurogastroenterol Motil. 2015 Mar;27(3):389-96. doi: 10.1111/nmo.12504. Epub 2015 Jan 3.
Impact factor:
Publication type: Paper in international publication
Authors: Accarino, A; Azpiroz, F; Campos, E; Gonzalez, A; Malagelada, C; Malagelada, J R; Mendez, S; Molne, L et al.
DOI: 10.1111/nmo.12504

An integrated catalog of reference genes in the human gut microbiome.

PMID: 24997786
Journal: NATURE BIOTECHNOLOGY
Year: 2014
Reference: Nat Biotechnol. 2014 Aug;32(8):834-41. doi: 10.1038/nbt.2942. Epub 2014 Jul 6.
Impact factor:
Publication type: Paper in international publication
Authors: Al-Aama, Jumana Yousuf; Antolin, Maria; Artiguenave, Francois; Arumugam, Manimozhiyan; Batto, Jean-Michel; Blottiere, Herve; Bork, Peer; Borruel, Natalia; Brechot, Christian; Bruls, Thomas et al.
DOI: 10.1038/nbt.2942

Expert consensus document. The International Scientific Association for Probiotics and Prebiotics consensus statement on the scope and appropriate use of the term probiotic.

PMID: 24912386
Journal: Nature Reviews Gastroenterology & Hepatology
Year: 2014
Reference: Nat Rev Gastroenterol Hepatol. 2014 Aug;11(8):506-14. doi: 10.1038/nrgastro.2014.66. Epub 2014 Jun 10.
Impact factor:
Publication type: Clinical guide
Authors: Calder, Philip C; Canani, Roberto Berni; Flint, Harry J; Gibson, Glenn R; Guarner, Francisco; Hill, Colin; Merenstein, Daniel J; Morelli, Lorenzo; Pot, Bruno; Reid, Gregor et al.
DOI: 10.1038/nrgastro.2014.66

Processing faecal samples: a step forward for standards in microbial community analysis.

PMID: 24884524
Journal: BMC MICROBIOLOGY
Year: 2014
Reference: BMC Microbiol. 2014 May 1;14:112. doi: 10.1186/1471-2180-14-112.
Impact factor:
Publication type: Paper in international publication
Authors: Azpiroz, Fernando; Dore, Joel; Guarner, Francisco; Manichanh, Chaysavanh; Martinez, Xavier; Mengels, Griet; Panda, Suchita; Santiago, Alba et al.
DOI: 10.1186/1471-2180-14-112

Microbiome Composition by Pyrosequencing in Mesenteric Lymph Nodes of Rats with CCl-Induced Cirrhosis.

PMID: 24296725
Journal: Journal of Innate Immunity
Year: 2014
Reference: J Innate Immun. 2014;6(3):263-71. doi: 10.1159/000356454. Epub 2013 Nov 29.
Impact factor:
Publication type: Paper in international publication
Authors: Camilo Nieto, Juan; Cuenca, Silvia; El Khader, Ismail; Guarner, Carlos; Guarner, Francisco; Juarez, Candido; Manichanh, Chaysavanh; Panda, Suchita; Sanchez, Elisabet; Sancho, Francesc et al.
DOI: 10.1159/000356454

Richness of human gut microbiome correlates with metabolic markers.

PMID: 23985870
Journal: NATURE
Year: 2013
Reference: Nature. 2013 Aug 29;500(7464):541-6. doi: 10.1038/nature12506.
Impact factor:
Publication type: Paper in international publication
Authors: Almeida, Mathieu; Antolin, Maria; Antolin, Maria; Artiguenave, Francois; Artiguenave, Francois; Arumugam, Manimozhiyan; Batto, Jean-Michel; Bertalan, Marcelo; Blottiere, Herve; Blottiere, Herve et al.
DOI: 10.1038/nature12506

Optimizing treatment for patients with irritable bowel syndrome with constipation.

PMID: 23859753
Journal: Expert review of gastroenterology & hepatology
Year: 2013
Reference: Expert Rev Gastroenterol Hepatol. 2013 Jul;7(5 Suppl 1):1-2. doi: 10.1586/17474124.2013.820048.
Impact factor:
Publication type: Paper in international publication
Authors: Malagelada, Juan-Ramon et al.
DOI: 10.1586/17474124.2013.820048

Adaptable image cuts for motility inspection using WCE.

PMID: 23098835
Journal: COMPUTERIZED MEDICAL IMAGING AND GRAPHICS
Year: 2013
Reference: Comput Med Imaging Graph. 2013 Jan;37(1):72-80. doi: 10.1016/j.compmedimag.2012.09.002. Epub 2012 Oct 23.
Impact factor:
Publication type: Paper in international publication
Authors: Azpiroz, Fernando; Drozdzal, Michal; Malagelada, Carolina; Radeva, Petia; Segui, Santi; Vitria, Jordi et al.
DOI: 10.1016/j.compmedimag.2012.09.002

The Spanish Pancreatic Club's recommendations for the diagnosis and treatment of chronic pancreatitis: part 2 (treatment).

PMID: 23395565
Journal: PANCREATOLOGY
Year: 2013
Reference: Pancreatology. 2013 Jan-Feb;13(1):18-28. doi: 10.1016/j.pan.2012.11.310. Epub 2012 Nov 27.
Impact factor:
Publication type: Paper in international publication
Authors: Abad-Gonzalez, A; Aparicio, J R; Aparisi, L; Boadas, J; Boix, E; de-Las-Heras, G; de-Madaria, E; Dominguez-Munoz, E; Farre, A; Fernandez-Cruz, L et al.
DOI: 10.1016/j.pan.2012.11.310

Storage conditions of intestinal microbiota matter in metagenomic analysis.

PMID: 22846661
Journal: BMC MICROBIOLOGY
Year: 2012
Reference: BMC Microbiol. 2012 Jul 30;12:158. doi: 10.1186/1471-2180-12-158.
Impact factor:
Publication type: Paper in international publication
Authors: Alastrue, Carmen; Azpiroz, Fernando; Cardona, Silvia; Cassellas, Montserrat; Dore, Joel; Eck, Anat; Gallart, Milagros; Guarner, Francisco; Manichanh, Chaysavanh; Roca, Joaquim et al.
DOI: 10.1186/1471-2180-12-158

Cellular and molecular basis of intestinal barrier dysfunction in the irritable bowel syndrome.

PMID: 22844557
Journal: Gut and Liver
Year: 2012
Reference: Gut Liver. 2012 Jul;6(3):305-15. Epub 2012 Jul 12.
Impact factor:
Publication type: Review in international publication
Authors: Gonzalez-Castro, Ana; Martinez, Cristina; Santos, Javier; Vicario, Maria et al.
DOI: 10.5009/gnl.2012.6.3.305

Relationships of hepatic and pancreatic biomarkers with the cholestatic syndrome and tumor stage in pancreatic cancer.

PMID: 22793268
Journal: BIOMARKERS
Year: 2012
Reference: Biomarkers. 2012 Sep;17(6):557-65. doi: 10.3109/1354750X.2012.701331. Epub 2012 Jul 16.
Impact factor:
Publication type: Paper in international publication
Authors: ; ; ; ; ; et al.
DOI: 10.3109/1354750X.2012.701331

World gastroenterology organisation global guidelines: probiotics and prebiotics october 2011.

PMID: 22688142
Journal: JOURNAL OF CLINICAL GASTROENTEROLOGY
Year: 2012
Reference: J Clin Gastroenterol. 2012 Jul;46(6):468-81.
Impact factor:
Publication type: Paper in international publication
Authors: de Paula, Juan Andres; Eliakim, Rami; Fedorak, Richard; Gangl, Alfred; Garisch, James; Guarner, Francisco; Karakan, Tarkan; Kaufmann, Pedro; Khan, Aamir G; Kim, Nayoung et al.
DOI: 10.1097/MCG.0b013e3182549092

Human gut microbiota and its relationship to health and disease.

PMID: 21729093
Journal: NUTRITION REVIEWS
Year: 2011
Reference: Nutr Rev. 2011 Jul;69(7):392-403. doi: 10.1111/j.1753-4887.2011.00402.x. Epub 2011 Jun 30.
Impact factor:
Publication type: Review in international publication
Authors: ; ; ; ; ; ; et al.
DOI: 10.1111/j.1753-4887.2011.00402.x

Thiopurine methyl-transferase activity and azathioprine metabolite concentrations do not predict clinical outcome in thiopurine-treated inflammatory bowel disease patients.

PMID: 21722149
Journal: ALIMENTARY PHARMACOLOGY & THERAPEUTICS
Year: 2011
Reference: Aliment Pharmacol Ther. 2011 Sep;34(5):544-54. doi: 10.1111/j.1365-2036.2011.04756.x. Epub 2011 Jul 3.
Impact factor:
Publication type: Paper in international publication
Authors: ; ; ; ; ; ; ; ; ; et al.
DOI: 10.1111/j.1365-2036.2011.04756.x

Effectiveness of Combined Pharmacologic and Ligation Therapy in High-Risk Patients With Acute Esophageal Variceal Bleeding.

PMID: 21625271
Journal: AMERICAN JOURNAL OF GASTROENTEROLOGY
Year: 2011
Reference: Am J Gastroenterol. 2011 Oct;106(10):1787-95. doi: 10.1038/ajg.2011.173. Epub 2011 May 31.
Impact factor:
Publication type: Paper in international publication
Authors: ; ; ; ; ; ; ; ; ; et al.
DOI: 10.1038/ajg.2011.173

Nursing resources and responsibilities according to hospital organizational model for management of inflammatory bowel disease in Spain.

PMID: 21575883
Journal: Journal of Crohns & Colitis
Year: 2011
Reference: J Crohns Colitis. 2011 Jun;5(3):211-7. Epub 2011 Feb 11.
Impact factor:
Publication type: Paper in international publication
Authors: Alfaro, Noelia; Casellas, Francesc; Garcia-Sanchez, Valle; Hernandez-Sampelayo, Paloma; Lazaro, Pablo; Marin, Laura; Oltra, Lorena; Seoane, Montserrat; Torrejon, Antonio; Vera, Maria Isabel et al.
DOI: 10.1016/j.crohns.2011.01.001

Reshaping the gut microbiome with bacterial transplantation and antibiotic intake.

PMID: 20736229
Journal: GENOME RESEARCH
Year: 2010
Reference: Genome Res. 2010 Oct;20(10):1411-9. Epub 2010 Aug 24.
Impact factor:
Publication type: Paper in international publication
Authors: Antolin, Maria; Gibert, Prudence; Guarner, Francisco; Guigo, Roderic; Knight, Rob; Llopis, Marta; Manichanh, Chaysavanh; Reeder, Jens; Varela, Encarna et al.
DOI: 10.1101/gr.107987.110

Prebiotic effects: metabolic and health benefits.

PMID: 20920376
Journal: BRITISH JOURNAL OF NUTRITION
Year: 2010
Reference: Br J Nutr. 2010 Aug;104 Suppl 2:S1-63.
Impact factor:
Publication type: Paper in international publication
Authors: Cani, Patrice D; Coxam, Veronique; Davicco, Marie-Jeanne; Delzenne, Nathalie M; Gibson, Glenn R; Guarner, Francisco; Hoyles, Lesley; Leotoing, Laurent; McCartney, Anne L; Meheust, Agnes et al.
DOI: 10.1017/S0007114510003363

Normal values in ambulatory oesophageal pH monitoring at two levels in Spain.

PMID: 20617860
Journal: REVISTA ESPANOLA DE ENFERMEDADES DIGESTIVAS
Year: 2010
Reference: Rev Esp Enferm Dig. 2010 Jul;102(7):406-12.
Impact factor:
Publication type: Paper in national publication
Authors: Azpiroz, F; Baudet, J S; Benages, A; Canga, F; Carrasco, J; Ciriza, C; Cucala, M; Dominguez, E; Faro, V; Garrigues, V et al.
DOI:

Chronological assessment of mast cell-mediated gut dysfunction and mucosal inflammation in a rat model of chronic psychosocial stress.

PMID: 20600818
Journal: BRAIN BEHAVIOR AND IMMUNITY
Year: 2010
Reference: Brain Behav Immun. 2010 Oct;24(7):1166-75. Epub 2010 Jun 25.
Impact factor:
Publication type: Paper in international publication
Authors: Alonso, Carmen; Azpiroz, Fernando; Gonzalez, Ana; Guila, Meritxell; Guilarte, Mar; Lobo, Beatriz; Martinez, Cristina; Pigrau, Marc; Ramos, Laura; Santos, Javier et al.
DOI: 10.1016/j.bbi.2010.06.002

Lactobacillus casei downregulates commensals' inflammatory signals in Crohn's disease mucosa.

PMID: 18839424
Journal: INFLAMMATORY BOWEL DISEASES
Year: 2009
Reference: Inflamm Bowel Dis. 2009 Feb;15(2):275-83.
Impact factor:
Publication type: Paper in international publication
Authors: Antolin, Maria; Borruel, Natalia; Carol, Monica; Casellas, Francesc; Espin-Basany, Eloy; Guarner, Francisco; Llopis, Marta; Malagelada, Juan-R; Martinez, Cristina et al.
DOI: 10.1002/ibd.20736

Faecal DNA and calprotectin as biomarkers of acute intestinal toxicity in patients undergoing pelvic radiotherapy.

PMID: 19392859
Journal: ALIMENTARY PHARMACOLOGY & THERAPEUTICS
Year: 2009
Reference: Aliment Pharmacol Ther. 2009 Jul 1;30(2):175-85.
Impact factor:
Publication type: Paper in international publication
Authors: Antolin, M; Giralt, J; Guarner, F; Malagelada, J-R; Varela, E; Verges, R et al.
DOI: 10.1111/j.1365-2036.2009.04019.x

Development, validation, and applicability of a symptoms questionnaire for lactose malabsorption screening.

PMID: 18716868
Journal: DIGESTIVE DISEASES AND SCIENCES
Year: 2009
Reference: Dig Dis Sci. 2009 May;54(5):1059-65.
Impact factor:
Publication type: Paper in international publication
Authors: Aparici, A; Casaus, M; Casellas, Francesc; Rodriguez, P; Varela, E et al.
DOI: 10.1007/s10620-008-0443-3

Non-anatomical intestinal transplantation.

PMID: 19335051
Journal: REVISTA ESPANOLA DE ENFERMEDADES DIGESTIVAS
Year: 2009
Reference: Rev Esp Enferm Dig. 2009 Feb;101(2):139-41, 141-3.
Impact factor:
Publication type: Paper in national publication
Authors: Abu-Suboh, M; Accarino, A; Armengol-Miro, J R; Azpiroz, F; Bilbao, I; Bueno, J; Caralt, M; Charco, R; Dot, J; Gavalda, J et al.
DOI:

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