Francesc Xavier Molero Richard Institutions of which they are part Main researcher Physiology and Pathophysiology of the Digestive Tract Vall Hebron Institut de Recerca Email Francesc Xavier Molero Richard Email Institutions of which they are part Main researcher Physiology and Pathophysiology of the Digestive Tract Vall Hebron Institut de Recerca
Research lines Pathophysiology and treatment of pancreatic disorders. The focus of our research is to study the series of pathophysiologic events leading to acute and chronic pancreatitis and, eventually, pancreatic cancer. We aim to take advantage of knowledge gained at our basic research program to design therapeutic strategies intended to prevent or ameliorate human pancreatic disorders. In rodent models of acute and chronic pancreatitis we examine pancreatic regeneration, fibrogenesis, acino-ductal trandiferentiation, stellate cell activation, epithelial-to-mesenchymal transition and cancer development. In human pancreatitis we investigate environmental and genetic determinants (with special focus at CFTR dysfunction) and new treatment modalities for acute and chronic pancreatitis. IP: Francesc Xavier Molero Richard Projects CFTR down regulation enhances pancreatic carcinogenesis and promotes cancer invasion and metastasis IP: Francesc Xavier Molero Richard Collaborators: Raquel Ibañez Ferrer Funding agency: Cystic Fibrosis Foundation Funding: 300565.29 Reference: CFTR_CFF_RESEARCH GRANTS - FALL 2021 Duration: 01/05/2022 - 30/04/2024 Contribución de la disfunción de CFTR al desarrollo y agresividad del cáncer de páncreas. Estimulación del crecimiento tumoral y metástasis por células estrelladas carentes de CFTR. IP: Francesc Xavier Molero Richard Collaborators: Laura Campderros Traver, Contribución de la disfunción de CFTR al desarrollo y agresividad del cáncer de páncreas. Estimulación del crecimiento tumoral y, Eva Polverino Funding agency: Instituto de Salud Carlos III Funding: 147620 Reference: PI22/00887 Duration: 01/01/2023 - 31/12/2025 Fisiologia i fisiopatologia digestiva IP: Fco Javier Santos Vicente Collaborators: Maria Vicario Perez, Beatriz Lobo Alvarez, Fernando Azpiroz Vidaur, Merce Albert Bayo, Natalia Borruel Sainz, Francesc Xavier Molero Richard, Francesc Casellas Jordá, Carmen Alonso Cotoner, Carolina Malagelada Prats, Jorge Serra Pueyo, Ana Maria Gonzalez Castro, Ariadna Aguilar Cayuelas, Elba Exposito Fernandez, Laura Campderros Traver, Blanca Grases Pintó, Virginia Robles Alonso, Adoración Nieto Ruiz, Elena Céspedes Martínez, Fisiologia i fisiopatologia digestiva, Ainara Rueda Farre, Danila Guagnozzi , Luis Gerardo Alcala Gonzalez, Ronald Benjamin Llerena Castro, Francisca Yañez Araya, Consuelo Cammarota Funding agency: AGAUR no fer servir-correcte 4301-37 Funding: 40000 Reference: 2021 SGR 00766 Duration: 01/01/2022 - 31/12/2024 Enhanced fibroinflammatory phenotype of pancreatic stellate cells devoid of CFTR. Exploring pathways for correction. IP: Francesc Xavier Molero Richard Collaborators: Laura Campderros Traver Funding agency: VERTEX PHARMACEUTICALS (SPAIN) SL Funding: 90750 Reference: 'VERTEX_IIS_2020_X.MOLERO Duration: 01/02/2020 - 25/05/2023 Pagination Current page 1 Page 2 Page 3 Page 4 Next page › Last page »
