Francesc Xavier Molero Richard Institutions of which they are part Physiology and Pathophysiology of the Digestive Tract Vall Hebron Institut de Recerca Email Francesc Xavier Molero Richard Email Institutions of which they are part Physiology and Pathophysiology of the Digestive Tract Vall Hebron Institut de Recerca
Research lines Pathophysiology and treatment of pancreatic disorders. The focus of our research is to study the series of pathophysiologic events leading to acute and chronic pancreatitis and, eventually, pancreatic cancer. We aim to take advantage of knowledge gained at our basic research program to design therapeutic strategies intended to prevent or ameliorate human pancreatic disorders. In rodent models of acute and chronic pancreatitis we examine pancreatic regeneration, fibrogenesis, acino-ductal trandiferentiation, stellate cell activation, epithelial-to-mesenchymal transition and cancer development. In human pancreatitis we investigate environmental and genetic determinants (with special focus at CFTR dysfunction) and new treatment modalities for acute and chronic pancreatitis. IP: Francesc Xavier Molero Richard Projects New tool based on Artificial Intelligence and Biomarkers for early non-invasive diagnosis of Pancreatic Cancer - AI-Early PanC IP: Stephanie Solange Tasayco Huaman Collaborators: Santiago Pérez Hoyos, Francesc Xavier Molero Richard, Joaquin Balsells Valls, Xavier Merino Casabiel, Joan Dot Bach Funding agency: Ministerio Ciencia, Innovación y Universidades Funding: 293321 Reference: CPP2022-009592 Duration: 01/10/2023 - 31/12/2026 CFTR down regulation enhances pancreatic carcinogenesis and promotes cancer invasion and metastasis IP: Stephanie Solange Tasayco Huaman Collaborators: Francesc Xavier Molero Richard, Raquel Ibañez Ferrer Funding agency: Cystic Fibrosis Foundation Funding: 300565.29 Reference: CFTR_CFF-RESEARCH GRANTS-FALL_2021 Duration: 01/05/2022 - 31/03/2026 Contribución de la disfunción de CFTR al desarrollo y agresividad del cáncer de páncreas. Estimulación del crecimiento tumoral y metástasis por células estrelladas carentes de CFTR. IP: Francesc Xavier Molero Richard Collaborators: Eva Polverino Funding agency: Instituto de Salud Carlos III Funding: 147620 Reference: PI22/00887 Duration: 01/01/2023 - 01/05/2023 Enhanced fibroinflammatory phenotype of pancreatic stellate cells devoid of CFTR. Exploring pathways for correction. IP: Francesc Xavier Molero Richard Collaborators: - Funding agency: Vertex Pharmaceuticals (Spain), S.L. Funding: 90750 Reference: VERTEX_X.MOLERO_IIS_2020 Duration: 01/02/2020 - 25/05/2023 Pagination Current page 1 Page 2 Page 3 Page 4 Next page › Last page »
