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Francesc Xavier Molero Richard

Institutions of which they are part

Physiology and Pathophysiology of the Digestive Tract
Vall Hebron Institut de Recerca

Research lines

Pathophysiology and treatment of pancreatic disorders.

The focus of our research is to study the series of pathophysiologic events leading to acute and chronic pancreatitis and, eventually, pancreatic cancer. We aim to take advantage of knowledge gained at our basic research program to design therapeutic strategies intended to prevent or ameliorate human pancreatic disorders. In rodent models of acute and chronic pancreatitis we examine pancreatic regeneration, fibrogenesis, acino-ductal trandiferentiation, stellate cell activation, epithelial-to-mesenchymal transition and cancer development. In human pancreatitis we investigate environmental and genetic determinants (with special focus at CFTR dysfunction) and new treatment modalities for acute and chronic pancreatitis.

IP: Francesc Xavier Molero Richard

Projects

Enhanced fibroinflammatory phenotype of pancreatic stellate cells devoid of CFTR. Exploring pathways for correction.

IP: Francesc Xavier Molero Richard
Collaborators: Laura Campderros Traver
Funding agency: VERTEX PHARMACEUTICALS (SPAIN) SL
Funding: 90749.34
Reference: 'VERTEX_IIS_2020_X.MOLERO
Duration: 01/02/2020 - 31/01/2022

Potenciación del fenotipo fibroinflamatorio y su rectificación con moduladores de autofagia en células estrelladas pancreáticas carentes de CFTR.

IP: Francesc Xavier Molero Richard
Collaborators: Joseane Willamil Dos Santos, Joaquin Balsells Valls, Adoración Nieto Ruiz, Encarna Varela Castro
Funding agency: Instituto de Salud Carlos III
Funding: 93170
Reference: PI18/00511
Duration: 01/01/2019 - 30/06/2023

Estudio para el desarrollo y validación de una huella genética para el diagnóstico de cáncer de páncreas y lesiones precursoras

IP: Francesc Xavier Molero Richard
Collaborators: -
Funding agency:
Funding:
Reference: PR(AG)196/2017
Duration: -

Unitat de Recerca del Sistema Digestiu (GRC)

IP: Fernando Azpiroz Vidaur
Collaborators: Maria Vicario Perez, Fco Javier Santos Vicente, Beatriz Lobo Alvarez, Claudia Maria Herrera de Guise, Natalia Borruel Sainz, María Antolín Mate, Francesc Xavier Molero Richard, Mar Guilarte Clavero, Francisco Guarner Aguilar, Francesc Casellas Jordá, Ana María Accarino Garaventa, Carmen Alonso Cotoner, Carolina Malagelada Prats, Ana Maria Gonzalez Castro, Marc Pigrau Pastor, Virginia Robles Alonso, Cristina Martínez Martínez, Encarna Varela Castro, Chaysavanh Manichanh , Elizabeth Barba Orozco
Funding agency: AGAUR
Funding: 30000
Reference: 2014 SGR 1285
Duration: 01/01/2014 - 31/12/2016

Related news

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