Matilde Lleonart Pajarin Institutions of which they are part Head of group Biomedical Research in Cancer Stem Cells Vall Hebron Institut de Recerca Email Matilde Lleonart Pajarin Email Institutions of which they are part Head of group Biomedical Research in Cancer Stem Cells Vall Hebron Institut de Recerca
Research lines Study of new genes involved in proliferation Searching for new proliferative genes/tumor suppressor genes is being performed at our laboratory by carring out genetic screens. By the use of retroviral vectors as carriers of a cDNA libraries (formed by mRNA from murine embryonic stem cells), primary cells are infected and screening for those clones able to bypass senescence are selected for further characterization. The marked morphological heterogeneity observed in several tumorigenic process, support the hypothesis that several cancers have their origin in a stem cell. It is believed that genes expressed by embryonic stem cells, may play an important role in the tumorigenic mechanism.This project unravels the effect of immortal genes existing in embryonic stem cells, when are forced to be expressed in primary and thereby mortal cells. These immortal genes are future candidate markers in tumors with potential prognosis value. The novel genes discovered, are being analyzed in the biopsies from patients with different kinds of tumors collected at the Pathology Department of the Vall d´Hebrón Hospital. IP: Matilde Lleonart Pajarin Pagination First page « Previous page ‹ Page 1 Current page 2 Projects Ayudas Margarita Salas IP: Matilde Lleonart Pajarin Collaborators: Yoelsis Garcia Mayea, Judit Álvarez González Funding agency: Ministerio de Universidades Funding: 0.01 Reference: MIU/M_SALAS/2021/GARCIA_UB Duration: 01/04/2022 - 31/03/2022 Novel terapéutic approaches against COVID-19 IP: Matilde Lleonart Pajarin Collaborators: Marina Bataller Fernández, Almudena Sanchez Garcia, Yoelsis Garcia Mayea Funding agency: Fundació La Marató de TV3 Funding: 161875 Reference: 202116 Duration: 23/09/2021 - 22/09/2024 New therapeutic approaches in head and neck cancer IP: Matilde Lleonart Pajarin Collaborators: Yoelsis Garcia Mayea, Jordi Temprana Salvador, Angel García Jiménez, Josep Castellví Vives, Laia Josa Culleré, Marina Bataller Fernández Funding agency: Instituto de Salud Carlos III Funding: 183920 Reference: PI20/00556 Duration: 01/01/2021 - 30/06/2025 Drug-screen against novel proteins involved in cancer resistance IP: Matilde Lleonart Pajarin Collaborators: Almudena Sanchez Garcia, Miriam Izquierdo Sans Funding agency: Fundació Institut de Recerca HUVH Funding: 50649.27 Reference: VHIR/BEQUESPREDOC/2019/SANCHEZ Duration: 14/09/2020 - 13/09/2023 Pagination First page « Previous page ‹ Page 1 Current page 2 Page 3 Page 4 Page 5 … Next page › Last page »
