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Cardiovascular Diseases

Cardiovascular Diseases group is a translational research group within the Cardiology Department of Vall d’Hebron Hospital that performs laboratory, clinical and epidemiological research. In the CIBERCV network we are within the topic of descriptor 2 “Arterial disease, thrombosis and myocardial ischemia-reperfusion injury”. Our contributions in these topics address the following lines: 

  • Myocardial ischemia-reperfusion injury (i.e. mechanisms of endogenous cardioprotection, ischemic conditioning and remodeling), 
  • Coronary artery disease (i.e. genetic factors involved in coronary artery disease, determinants of thrombotic complications and prognosis), 
  • Aortic diseases (i.e. determinants of aorta dilatation, aortic biomechanics abnormalities in Marfan´s syndrome, and new imaging methods), 
  • Congenital/familiar heart diseases (i.e. genetic determinants and prognosis factors). 

In the CIBERESP network, our group is interested in the study of effectiveness/cost-effectiveness of cardiovascular interventions, health outcome research and methods in clinical research. The group has 19 principal investigators, 32 active projects and clinical trial and has been done 142 publications in 2020.

Team

Laura Galián Gay

Laura Galián Gay

Main researcher
Cardiovascular Diseases
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Natalia Gonzalez Otero

Natalia Gonzalez Otero

Cardiovascular Diseases
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Aitor Uribarri Gonzalez

Aitor Uribarri Gonzalez

Senior researcher
Cardiovascular Diseases
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Ana Belén  Méndez Fernández

Ana Belén Méndez Fernández

Main researcher
Cardiovascular Diseases
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Ferran Gran Ipiña

Ferran Gran Ipiña

Senior researcher
Cardiovascular Diseases
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Pau  Rello Sabaté

Pau Rello Sabaté

Predoctoral researcher
Cardiovascular Diseases
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Laura Galián Gay

Laura Galián Gay

Main researcher
Cardiovascular Diseases
Read more
Natalia Gonzalez Otero

Natalia Gonzalez Otero

Cardiovascular Diseases
Read more
Aitor Uribarri Gonzalez

Aitor Uribarri Gonzalez

Senior researcher
Cardiovascular Diseases
Read more
Ana Belén  Méndez Fernández

Ana Belén Méndez Fernández

Main researcher
Cardiovascular Diseases
Read more
Ferran Gran Ipiña

Ferran Gran Ipiña

Senior researcher
Cardiovascular Diseases
Read more
Pau  Rello Sabaté

Pau Rello Sabaté

Predoctoral researcher
Cardiovascular Diseases
Read more

Projects

Aneurismas degenerativos de la aorta ascendente: ¿están relacionados los fenotipos de dilatación con su etiología, patofisiología y pronóstico?

IP: Jose Fernando Rodríguez Palomares
Collaborators: Guillem Casas Masnou, Ruperto Olivero Soldevila, Alicia Fresno González, Javier Limeres Freire, Lydia Dux-Santoy Hurtado, Laura Fruitós Montané, Raul Aguilar Lopez, Miguel García Gabilondo
Funding agency: Instituto de Salud Carlos III
Funding: 200000
Reference: PI23/01397
Duration: 01/01/2024 - 31/12/2026

Mechanisms of metabolic adaptation after weight loss in obesity. Clinical phenotyping and therapeutic approach.

IP: Andreea Ciudin Mihai
Collaborators: Cristina Gamez Cenzano, Eduard Rodenas Alesina, Ana Marti Delgado, Fiorella Ximena Palmas Candia, Bruno García del Blanco, Ana Belén Méndez Fernández, Ana Maria Ciscar Bellés, Aleix Olivella San emeterio, Marta Comas Martínez, Alvaro Calabuig Goena, Enzamaría Fidilio Meli, Marco Tomasino
Funding agency: Instituto de Salud Carlos III
Funding: 165000
Reference: PI23/01209
Duration: 01/01/2024 - 31/12/2026

Role of amino acid metabolism reprogramming and calpain deregulation in fibroblasts activation and diffuse myocardial fibrosis in heart failure

IP: Javier Inserte Igual
Collaborators: José Antonio Barrabés Riu, David Aluja Gonzalez, Juan Garrido Oliver, Elisabet Miro Casas, Sara Delgado Tomás
Funding agency: Instituto de Salud Carlos III
Funding: 152500
Reference: PI23/00068
Duration: 01/01/2024 - 31/12/2026

Papel de los canales TRPV4 en la fibrosis ventricular derecha: identificación de nuevos mecanismos moleculares y desarrollo de nuevas técnicas de diagnóstico

IP: Begoña Benito Villabriga
Collaborators: Laia Yañez Bisbe, Berta Miranda Barrio, Gino Freddy Sena Ganse , Papel de los canales TRPV4 en la fibrosis ventricular derecha: identificación de nuevos mecanismos moleculares y desarrollo de n
Funding agency: Instituto de Salud Carlos III
Funding: 152500
Reference: PI23/01854
Duration: 01/01/2024 - 31/12/2026

Blog

News

The grants, amounting to more than €533,000 for VHIR, will allow clinical duties to be partially released over three years to promote strategic research projects in obesity, respiratory diseases, aortic pathology and metabolic fatty liver disease.

Funding has been obtained for 43 projects under the calls for Health R&D&I Projects, Health Technology Development, and Independent Clinical Research

The project aims to improve prevention, diagnosis, and treatment through computational biomedicine, innovative therapies, and the transfer of knowledge into clinical practice.

Rates

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Echocardiography Rates

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Hemodynamics Rates

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