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Cardiovascular Diseases

Cardiovascular Diseases group is a translational research group within the Cardiology Department of Vall d’Hebron Hospital that performs laboratory, clinical and epidemiological research. In the CIBERCV network we are within the topic of descriptor 2 “Arterial disease, thrombosis and myocardial ischemia-reperfusion injury”. Our contributions in these topics address the following lines: 

  • Myocardial ischemia-reperfusion injury (i.e. mechanisms of endogenous cardioprotection, ischemic conditioning and remodeling), 
  • Coronary artery disease (i.e. genetic factors involved in coronary artery disease, determinants of thrombotic complications and prognosis), 
  • Aortic diseases (i.e. determinants of aorta dilatation, aortic biomechanics abnormalities in Marfan´s syndrome, and new imaging methods), 
  • Congenital/familiar heart diseases (i.e. genetic determinants and prognosis factors). 

In the CIBERESP network, our group is interested in the study of effectiveness/cost-effectiveness of cardiovascular interventions, health outcome research and methods in clinical research. The group has 19 principal investigators, 32 active projects and clinical trial and has been done 142 publications in 2020.

Publications

Echocardiography in the acute phase of COVID-19 infection: impact on management and prognosis.

PMID: 34972647
Journal: REVISTA ESPANOLA DE CARDIOLOGIA
Year: 2022
Reference: Rev Esp Cardiol (Engl Ed). 2022 Jun;75(6):532-535. doi: 10.1016/j.rec.2021.11.012. Epub 2021 Dec 14.
Impact factor: 4.753
Publication type: Letter whit IF
Authors: Gonzalez-Del-Hoyo, Maribel, Servato, Luz, Rodenas, Eduardo, Baneras, Jordi, Ferreira-Gonzalez, Ignacio, Rodriguez-Palomares, Jose et al.
DOI: 10.1016/j.rec.2021.11.012

Characterization of hereditary transthyretin cardiac amyloidosis in Spain.

PMID: 34711514
Journal: REVISTA ESPANOLA DE CARDIOLOGIA
Year: 2022
Reference: Rev Esp Cardiol (Engl Ed). 2022 Jun;75(6):488-495. doi: 10.1016/j.rec.2021.07.020. Epub 2021 Oct 26.
Impact factor: 4.753
Publication type: Paper in national publication
Authors: Alvarez Rubio, Jorge, Manovel Sanchez, Ana Jose, Gonzalez-Costello, Jose, Garcia-Pavia, Pablo, Limeres Freire, Javier, Garcia-Pinilla, Jose Manuel, Zorio Grima, Esther, Garcia-Alvarez, Ana, Valverde Gomez, Maria, Espinosa Castro, M Angeles et al.
DOI: 10.1016/j.rec.2021.07.020

Early clinical outcomes after transaxillary versus transfemoral TAVI. Data from the Spanish TAVI registry.

PMID: 34711513
Journal: REVISTA ESPANOLA DE CARDIOLOGIA
Year: 2022
Reference: Rev Esp Cardiol (Engl Ed). 2022 Jun;75(6):479-487. doi: 10.1016/j.rec.2021.07.019. Epub 2021 Oct 26.
Impact factor: 4.753
Publication type: Paper in national publication
Authors: Urbano Carrillo, Cristobal, Albarran, Agustin, Ruiz-Salmeron, Rafael, Moreu, Jose, Gheorghe, Livia, Arzamendi, Dabit, Yanes-Bowden, Geoffrey, Diaz, Jose, Perez-Moreiras, Ignacio, Artaiz, Miguel et al.
DOI: 10.1016/j.rec.2021.07.019

2021 ESC Guidelines on cardiac pacing and cardiac resynchronization therapy.

PMID: 34455427
Journal: EUROPACE
Year: 2022
Reference: Europace. 2022 Jan 4;24(1):71-164. doi: 10.1093/europace/euab232.
Impact factor: 5.214
Publication type: Paper in international publication
Authors: De Vinuesa, Pastora Gallego Garcia, Glikson, Michael, Aboyans, Victor, Arbelo, Elena, Asteggiano, Riccardo, Baron-Esquivias, Gonzalo, Bauersachs, Johann, Biffi, Mauro, Birgersdotter-Green, Ulrika, Bongiorni, Maria Grazia et al.
DOI: 10.1093/europace/euab232

Transcatheter Versus Surgical Aortic Valve Replacement in Patients With Complex Coronary Artery Disease.

PMID: 34794656
Journal: JACC-Cardiovascular Interventions
Year: 2021
Reference: JACC Cardiovasc Interv. 2021 Nov 22;14(22):2490-2499. doi: 10.1016/j.jcin.2021.08.073.
Impact factor: 11.195
Publication type: Paper in international publication
Authors: Matta, Anthony, Alperi, Alberto, Mohammadi, Siamak, Campelo-Parada, Francisco, Munoz-Garcia, Erika, Nombela-Franco, Luis, Faroux, Laurent, Veiga, Gabriela, Serra, Vicenc, Fischer, Quentin et al.
DOI: 10.1016/j.jcin.2021.08.073

Radiomics-Based Classification of Left Ventricular Non-compaction, Hypertrophic Cardiomyopathy, and Dilated Cardiomyopathy in Cardiovascular Magnetic Resonance.

PMID: 34778415
Journal: Frontiers in Cardiovascular Medicine
Year: 2021
Reference: Front Cardiovasc Med. 2021 Oct 29;8:764312. doi: 10.3389/fcvm.2021.764312. eCollection 2021.
Impact factor: 6.05
Publication type: Paper in international publication
Authors: Izquierdo, Cristian, Casas, Guillem, Martin-Isla, Carlos, Campello, Victor M, Guala, Andrea, Gkontra, Polyxeni, Rodriguez-Palomares, Jose F, Lekadir, Karim et al.
DOI: 10.3389/fcvm.2021.764312

Is the lipid paradox finally unmasked?

PMID: 34750616
Journal: European Heart Journal-Acute Cardiovascular Care
Year: 2021
Reference: Eur Heart J Acute Cardiovasc Care. 2021 Dec 6;10(9):988-989. doi: 10.1093/ehjacc/zuab087.
Impact factor: 4.696
Publication type: Editorail in international publication
Authors: Ferreira-Gonzalez, Ignacio et al.
DOI: 10.1093/ehjacc/zuab087

Comorbidity burden and revascularization benefit in elderly patients with acute coronary syndrome.

PMID: 32778402
Journal: REVISTA ESPANOLA DE CARDIOLOGIA
Year: 2021
Reference: Rev Esp Cardiol (Engl Ed). 2021 Sep;74(9):765-772. doi: 10.1016/j.rec.2020.06.015. Epub 2020 Aug 7.
Impact factor: 4.753
Publication type: Paper in national publication
Authors: Marin, Francisco, Ruiz-Nodar, Juan M, Vicente-Ibarra, Nuria, Alonso Salinas, Gonzalo L, Rigueiro, Pedro, Abu-Assi, Emad, Formiga, Frances, Nunez, Julio, Nunez, Eduardo, Ariza-Sole, Albert et al.
DOI: 10.1016/j.rec.2020.06.015

2019 ESC Guidelines for the management of patients with supraventricular tachycardiaThe Task Force for the management of patients with supraventricular tachycardia of the European Society of Cardiology (ESC).

PMID: 31504425
Journal: EUROPEAN HEART JOURNAL
Year: 2020
Reference: Eur Heart J. 2020 Feb 1;41(5):655-720. doi: 10.1093/eurheartj/ehz467.
Impact factor: 22.673
Publication type: Paper in international publication
Authors: Kanagaratnam, Prapa, Ho, Siew Yen, Kaski, Juan-Carlos, Kuck, Karl-Heinz, Lambiase, Pier David, Sacher, Frederic, Sarquella-Brugada, Georgia, Suwalski, Piotr, Zaza, Antonio, De Potter, Tom et al.
DOI: 10.1093/eurheartj/ehz467

Comments on the 2019 ESC guidelines on supraventricular tachycardia.

PMID: 32349912
Journal: REVISTA ESPANOLA DE CARDIOLOGIA
Year: 2020
Reference: Rev Esp Cardiol (Engl Ed). 2020 Jun;73(6):445-451. doi: 10.1016/j.rec.2019.12.024. Epub 2020 Apr 26.
Impact factor: 4.642
Publication type: Editorial in national publication
Authors: Andres Lahuerta, Ana, Baron, Gonzalo, Escobar, Carlos, Fiol, Miquel, Fortuny, Elena, Gonzalez Torrecilla, Esteban, Rodriguez Font, Enrique, Ruiz Granel, Ricardo, Arribas, Fernando, Berga Congost, Gemma et al.
DOI: 10.1016/j.rec.2019.12.024

Comments on the 2019 ESC guidelines on acute pulmonary embolism.

PMID: 32349911
Journal: REVISTA ESPANOLA DE CARDIOLOGIA
Year: 2020
Reference: Rev Esp Cardiol (Engl Ed). 2020 Jun;73(6):452-456. doi: 10.1016/j.rec.2019.12.022. Epub 2020 Apr 27.
Impact factor: 4.642
Publication type: Editorial in national publication
Authors: Bonanad Lozano, Clara, Rodrigo, Ana Isabel Huelmos, Fernandez, Teresa Lopez, Lopez de Sa, Esteban, Martin Asenjo, Roberto, Roldan Rabadan, Inmaculada, Arribas, Fernando, Berga Congost, Gemma, Bueno, Hector, Evangelista, Arturo et al.
DOI: 10.1016/j.rec.2019.12.022

Large Vessel Occlusion is Independently Associated with Atrial Fibrillation Detection.

PMID: 32347993
Journal: EUROPEAN JOURNAL OF NEUROLOGY
Year: 2020
Reference: Eur J Neurol. 2020 Aug;27(8):1618-1624. doi: 10.1111/ene.14281. Epub 2020 May 27.
Impact factor: 4.516
Publication type: Paper in international publication
Authors: Penalba, Anna, Pala, Elena, Rodriguez, Maite, De Lera Alfonso, Mercedes, Arenillas, Juan F, Cabezas, Juan Antonio, Moniche, Francisco, de Torres, Reyes, Montaner, Joan, Gonzalez-Alujas, Teresa et al.
DOI: 10.1111/ene.14281

Safety of drug-eluting stents compared to bare metal stents in patients with an indication for long-term oral anticoagulation: A propensity score matched analysis.

PMID: 30925398
Journal: THROMBOSIS RESEARCH
Year: 2019
Reference: Thromb Res. 2019 May;177:180-186. doi: 10.1016/j.thromres.2019.02.021. Epub 2019 Mar 14.
Impact factor: 3.266
Publication type: Paper in international publication
Authors: Del Blanco, Bruno Garcia, Ferreira-Gonzalez, Ignacio, Mutuberria, Maria, Alfonso, Fernando, Bueno, Hector, Cequier, Angel, Prendergast, Bernard, Zueco, Javier, Rodriguez-Leor, Oriol, Barrabes, Jose A et al.
DOI: 10.1016/j.thromres.2019.02.021

The current role of echocardiography in acute aortic syndrome.

PMID: 30921764
Journal: Echo research and practice
Year: 2019
Reference: Echo Res Pract. 2019 Jun 1;6(2):R53-R63. doi: 10.1530/ERP-18-0058.
Impact factor: 0
Publication type: Review in international publication
Authors: Evangelista, Arturo, Maldonado, Giuliana, Gruosso, Domenico, Gutierrez, Laura, Granato, Chiara, Villalva, Nicolas, Galian, Laura, Gonzalez-Alujas, Teresa, Teixido, Gisela, Rodriguez-Palomares, Jose et al.
DOI: 10.1530/ERP-18-0058

Increased rotational flow in the proximal aortic arch is associated with its dilation in bicuspid aortic valve disease.

PMID: 30919887
Journal: European Heart Journal-Cardiovascular Imaging
Year: 2019
Reference: Eur Heart J Cardiovasc Imaging. 2019 Dec 1;20(12):1407-1417. doi: 10.1093/ehjci/jez046.
Impact factor: 5.26
Publication type: Paper in international publication
Authors: Dux-Santoy, Lydia, Guala, Andrea, Teixido-Tura, Gisela, Ruiz-Munoz, Aroa, Maldonado, Giuliana, Villalva, Nicolas, Galian, Laura, Valente, Filipa, Gutierrez, Laura, Gonzalez-Alujas, Teresa et al.
DOI: 10.1093/ehjci/jez046

Familial clustering of bicuspid aortic valve and its relationship with aortic dilation in first-degree relatives.

PMID: 30322846
Journal: HEART
Year: 2019
Reference: Heart. 2019 Apr;105(8):603-608. doi: 10.1136/heartjnl-2018-313802. Epub 2018 Oct 15.
Impact factor: 5.082
Publication type: Paper in international publication
Authors: Galian-Gay, Laura, Carro Hevia, Amelia, Teixido-Tura, Gisela, Rodriguez Palomares, Jose, Chaverri, Adriana Rodriguez, Delgado Jimenez, Juan Francisco, Garcia-Aranda, Beatriz, Rodriguez-Bailon, Isabel, Yotti, Raquel, Espinosa, M Angeles et al.
DOI: 10.1136/heartjnl-2018-313802

Methodology of the (18)F-FDG PET/TC cardiac for the diagnosis of prosthetic endocarditis and intracardiac devices.

PMID: 29496402
Journal: Revista Espanola de Medicina Nuclear e Imagen Molecular
Year: 2018
Reference: Rev Esp Med Nucl Imagen Mol. 2018 May - Jun;37(3):163-171. doi: 10.1016/j.remn.2018.01.002. Epub 2018 Feb 26.
Impact factor: 1.202
Publication type: Paper in national publication
Authors: Aguade Bruix, S, Roque Perez, A, Cuellar Calabria, H, Pizzi, M N et al.
DOI: 10.1016/j.remn.2018.01.002

3D axial and circumferential wall shear stress from 4D flow MRI data using a finite element method and a laplacian approach.

PMID: 28980342
Journal: MAGNETIC RESONANCE IN MEDICINE
Year: 2018
Reference: Magn Reson Med. 2018 May;79(5):2816-2823. doi: 10.1002/mrm.26927. Epub 2017 Oct 4.
Impact factor: 4.082
Publication type: Paper in international publication
Authors: Sotelo, Julio, Dux-Santoy, Lydia, Guala, Andrea, Rodriguez-Palomares, Jose, Evangelista, Arturo, Sing-Long, Carlos, Mura, Joaquin, Hurtado, Daniel E, Uribe, Sergio, Urbina, Jesus et al.
DOI: 10.1002/mrm.26927

Three- and 6-month optical coherence tomographic surveillance following percutaneous coronary intervention with the Angiolite(R) drug-eluting stent: The ANCHOR study.

PMID: 28707379
Journal: CATHETERIZATION AND CARDIOVASCULAR INTERVENTIONS
Year: 2018
Reference: Catheter Cardiovasc Interv. 2018 Feb 15;91(3):435-443. doi: 10.1002/ccd.27189. Epub 2017 Jul 14.
Impact factor: 2.602
Publication type: Paper in international publication
Authors: Perez de Prado, Armando, Nombela-Franco, Luis, de la Torre Hernandez, Jose M, Ortas Nadal, Rosario, Iniguez-Romo, Andres, Jimenez, Gustavo, Fernandez-Vazquez, Felipe, Cuellas-Ramon, Carlos, Gonzalo, Nieves, Alfonso Jimenez Diaz, Victor et al.
DOI: 10.1002/ccd.27189

Delay from Diagnosis to Surgery in Transferred Type A Aortic Dissection.

PMID: 29180025
Journal: AMERICAN JOURNAL OF MEDICINE
Year: 2018
Reference: Am J Med. 2018 Mar;131(3):300-306. doi: 10.1016/j.amjmed.2017.11.009. Epub 2017 Nov 24.
Impact factor: 5.117
Publication type: Paper in international publication
Authors: Tolenaar, Jip L, Harris, Kevin M, Strauss, Craig, Sundt, Thoralf M, Tsai, Thomas T, Peterson, Mark D, Evangelista, Arturo, Montgomery, Daniel G, Kline-Rogers, Eva, Nienaber, Christoph A et al.
DOI: 10.1016/j.amjmed.2017.11.009

Meeting report from the 2nd International Symposium on New Frontiers in Cardiovascular Research. Protecting the cardiovascular system from ischemia: between bench and bedside.

PMID: 26667317
Journal: BASIC RESEARCH IN CARDIOLOGY
Year: 2016
Reference: Basic Res Cardiol. 2016 Jan;111(1):7. doi: 10.1007/s00395-015-0527-0. Epub 2015 Dec 14.
Impact factor: 6.008
Publication type: Paper in international publication
Authors: Boisvert, William A, Cabrera-Fuentes, Hector A, Alba-Alba, Corina, Aragones, Julian, Bernhagen, Jurgen, Fleming, Ingrid, Garcia-Dorado, David, Lecour, Sandrine, Liehn, Elisa, Marber, Michael S et al.
DOI: 10.1007/s00395-015-0527-0

Heterogeneity of aortic disease severity in patients with Loeys-Dietz syndrome.

PMID: 26848186
Journal: HEART
Year: 2016
Reference: Heart. 2016 Apr;102(8):626-32. doi: 10.1136/heartjnl-2015-308535. Epub 2016 Feb 4.
Impact factor: 5.693
Publication type: Paper in international publication
Authors: Teixido-Tura, Gisela, Franken, Romy, Galuppo, Valentina, Gutierrez Garcia-Moreno, Laura, Borregan, Mar, Mulder, Barbara J M, Garcia-Dorado, David, Evangelista, Artur et al.
DOI: 10.1136/heartjnl-2015-308535

Impact of Triple Therapy in Elderly Patients with Atrial Fibrillation Undergoing Percutaneous Coronary Intervention.

PMID: 26808678
Journal: PLoS One
Year: 2016
Reference: PLoS One. 2016 Jan 25;11(1):e0147245. doi: 10.1371/journal.pone.0147245. eCollection 2016.
Impact factor: 3.057
Publication type: Paper in international publication
Authors: Bueno, Hector, Alfonso, Fernando, Cequier, Angel, Zueco, Javier, Rodriguez-Leor, Oriol, Tornos, Pilar, Garcia-Dorado, David, Barrabes, Jose A, Alonso, Albert, Mutuberria, Maria et al.
DOI: 10.1371/journal.pone.0147245

Hand-held cardiac ultrasound screening performed by family doctors with remote expert support interpretation.

PMID: 26802099
Journal: PROGRESS IN COMPUTATIONAL FLUID DYNAMICS
Year: 2016
Reference: Heart. 2016 Mar 1;102(5):376-82. doi: 10.1136/heartjnl-2015-308421. Epub 2016 Jan 22.
Impact factor: 0.288
Publication type: Paper in international publication
Authors: Evangelista, Arturo, Galuppo, Valentina, Mendez, Judith, Evangelista, Lidia, Arpal, Lidia, Rubio, Carles, Vergara, Montserrat, Liceran, Manuela, Lopez, Francesc, Sales, Carlos et al.
DOI: 10.1136/heartjnl-2015-308421

[Diagnosis and treatment of familial hypercholesterolemia in Spain: Consensus document.]

PMID: 24704195
Journal: Atencion Primaria
Year: 2015
Reference: Aten Primaria. 2015 Jan;47(1):56-65. doi: 10.1016/j.aprim.2013.12.015. Epub 2014 Apr 3.
Impact factor: 0.953
Publication type: Paper in national publication
Authors: Mata, Pedro, Alonso, Rodrigo, Ruiz, Antonio, Gonzalez-Juanatey, Jose R, Badimon, Lina, Diaz-Diaz, Jose L, Munoz, Maria Teresa, Muniz, Ovidio, Galve, Enrique, Irigoyen, Luis et al.
DOI: 10.1016/j.aprim.2013.12.015

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News

The consensus document is the result of multidisciplinary work that takes into account the risks associated with all stages of women's lives and the differences compared to men.

The study, which involved Vall d'Hebron, developed an action plan to efficiently allocate resources to patients most at risk of suffering this complication.

In light of this evidence, hospitals such as Vall d'Hebron have already started to include warnings about environmental pollution in their hospital discharge plans after a myocardial infarction.