Skip to main content

Clinical Biochemistry, Drug Delivery & Therapy

The Clinical Biochemistry, Drug Delivery & Therapy (CB-DDT) group arises from the merger of two VHIR groups, the Clinical Biochemistry group and the Drug Delivery and Targeting group, which they develop preclinical and clinical research in the diagnosis and therapy of different diseases.

With a direct link to the Clinical Biochemistry service of the Vall d'Hebron Hospital, our scope of action ranges from the analysis of massive data coming from the service, the development of diagnostic and prognostic biomarkers, evaluation of existing therapies and the development of new therapeutic strategies based on nanotechnology.

In terms of specific pathologies or indications, the group has an extensive track record in basic and applied research in cancer (new biomarkers, therapeutic targets and new treatments), metabolopathies (biomarkers and improvements in enzyme replacement therapy), kidney disease and liver disease.

Team

Roser Ferrer  Costa

Roser Ferrer Costa

Head of group
Clinical Biochemistry, Drug Delivery & Therapy (CB-DDT)
Read more
Joan López Hellin

Joan López Hellin

Main researcher
Clinical Biochemistry, Drug Delivery & Therapy (CB-DDT)
Read more
Joaquin Seras Franzoso

Joaquin Seras Franzoso

Main researcher
Clinical Biochemistry, Drug Delivery & Therapy (CB-DDT)
Read more
Simon Schwartz Navarro

Simon Schwartz Navarro

Main researcher
Clinical Biochemistry, Drug Delivery & Therapy (CB-DDT)
Read more
Zamira Vanessa Diaz Riascos

Zamira Vanessa Diaz Riascos

Main researcher
Clinical Biochemistry, Drug Delivery & Therapy (CB-DDT)
Read more
Diana Fernandes de Rafael

Diana Fernandes de Rafael

Main researcher
Clinical Biochemistry, Drug Delivery & Therapy (CB-DDT)
Read more
Roser Ferrer  Costa

Roser Ferrer Costa

Head of group
Clinical Biochemistry, Drug Delivery & Therapy (CB-DDT)
Read more
Joan López Hellin

Joan López Hellin

Main researcher
Clinical Biochemistry, Drug Delivery & Therapy (CB-DDT)
Read more
Joaquin Seras Franzoso

Joaquin Seras Franzoso

Main researcher
Clinical Biochemistry, Drug Delivery & Therapy (CB-DDT)
Read more
Simon Schwartz Navarro

Simon Schwartz Navarro

Main researcher
Clinical Biochemistry, Drug Delivery & Therapy (CB-DDT)
Read more
Zamira Vanessa Diaz Riascos

Zamira Vanessa Diaz Riascos

Main researcher
Clinical Biochemistry, Drug Delivery & Therapy (CB-DDT)
Read more
Diana Fernandes de Rafael

Diana Fernandes de Rafael

Main researcher
Clinical Biochemistry, Drug Delivery & Therapy (CB-DDT)
Read more

Research lines

Anàlisi de dades massives (big data), explotació de dades i mostres als Laboratoris Clínics

IP: Roser Ferrer Costa

Desenvolupament de models animals per l'avaluació ràpida i eficient de tractaments nanotecnològics

IP: Desenvolupament de models animals per l'avaluació ràpida i eficient de tractaments nanotecnològics

Desenvolupament i optimització de mètodes diagnòstics

IP: Joan López Hellin

Diagnosis, prognosis i monitoratge de malalties minoritàries, especialment malalties metabòliques

IP: Clara Carnicer Cáceres

Projects

SPM4.0: Autonomous Scanning Probe Microscopy for Life Sciences and Medicine powered by Artificial Intelligence

IP: -
Collaborators: -
Funding agency: EUROPEAN COMMISSION
Funding: 251971.2
Reference: SPM40_F.ANDRADE_MSCA-DN2023
Duration: 01/11/2024 - 31/10/2028

Project-COMFORT: Patient-Centric blOod saMpling FOr impRoved healThcare

IP: Simon Schwartz Navarro
Collaborators: Roser Ferrer Costa, Concepció Jacobs Cachá
Funding agency: EUROPEAN COMMISSION
Funding: 288262.5
Reference: COMFORT- HE--JU-IHI-2023-04
Duration: 01/11/2024 - 30/04/2028

ERDERA: European Rare Disease Research Alliance

IP: M Mar Mañu Pereira
Collaborators: Augusto Cesar Sao Aviles, Patricia González Ruiz, Claire Diot, Miguel Chillon Rodriguez, Simon Schwartz Navarro, Sara Isabel Reidel
Funding agency: EUROPEAN COMMISSION
Funding: 1252083.33
Reference: ERDERA/EC/HLTH-2023-DISEASE-07-01/2023/MAÑU
Duration: 01/09/2024 - 31/08/2031

Evaluation of an innovative strategy based on nanoparticles-loaded hydrogels as a safe and sustained intraperitoneal chemotherapy in mucinous adenocarcinomas

IP: -
Collaborators: Roser Ferrer Costa, Diana Fernandes de Rafael
Funding agency: Asociación Española Contra el Cáncer
Funding: 10000
Reference: SNRGS247164DASI
Duration: 01/06/2024 - 31/05/2026

Thesis

Estudio de la forma soluble de la enzima convertidora de angiotensina tipo 2 (sACE2 y otros biomarcadores en pacientes con Coronavirus Disease 2019 (COVID-19).

PhD student: Noelia Díaz Troyano
Director/s: Roser Ferrer Costa, Francisco Rodríguez Frias
University: Universitat Autònoma de Barcelona
Year: 2024

Medicina individualitzada i de precisió al laboratori clínic mitjançant l'ús de la cromatografia líquida i l'espectrometria de masses com a eines d'anàlisi

PhD student: Yolanda Villena Ortiz
Director/s: Francisco Rodríguez Frias, Joan López Hellin
University:
Year: 2024

Estudio de biomarcadores de riesgo de fibrosis hepática y de respuesta precoz a la cirugía bariátrica en un contexto de Enfermedad del hígado graso asociado a disfunción metabólica y obesidad severa

PhD student: Pablo Gabriel Medina
Director/s: Roser Ferrer Costa, David Martinez Selva, David Martinez Selva
University: Universitat Autònoma de Barcelona
Year: 2024

Comparació de mètodes indirectes (classics i novells) per establir intervals de referència

PhD student: Luisa Maria Martinez Sánchez
Director/s: Francisco Rodríguez Frias
University: Universitat Autònoma de Barcelona
Year: 2023

Mechanisms of androgen metabolism reprogramming in aggressive prostate cancer models and the association between androgens and COVID-19

PhD student: Emily Marisol Toscano Guerra
Director/s: Rosanna Paciucci Barzanti
University: Universitat Autònoma de Barcelona
Year: 2023

Blog

News

The study results show that the local presence of IL-1β promotes the development of myeloid cells with an immunosuppressive function.

The grants promote new therapeutic strategies and diagnostic tools in highly complex tumors such as glioblastoma, triple-negative breast cancer, and endometrial cancer.

The project aims to improve prevention, diagnosis, and treatment through computational biomedicine, innovative therapies, and the transfer of knowledge into clinical practice.