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Clinical Biochemistry, Drug Delivery & Therapy

The Clinical Biochemistry, Drug Delivery & Therapy (CB-DDT) group arises from the merger of two VHIR groups, the Clinical Biochemistry group and the Drug Delivery and Targeting group, which they develop preclinical and clinical research in the diagnosis and therapy of different diseases.

With a direct link to the Clinical Biochemistry service of the Vall d'Hebron Hospital, our scope of action ranges from the analysis of massive data coming from the service, the development of diagnostic and prognostic biomarkers, evaluation of existing therapies and the development of new therapeutic strategies based on nanotechnology.

In terms of specific pathologies or indications, the group has an extensive track record in basic and applied research in cancer (new biomarkers, therapeutic targets and new treatments), metabolopathies (biomarkers and improvements in enzyme replacement therapy), kidney disease and liver disease.

Team

Maria del Pilar Reimundo Diaz-Fierros

Maria del Pilar Reimundo Diaz-Fierros

Postdoctoral researcher
Clinical Biochemistry, Drug Delivery & Therapy (CB-DDT)
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Diego Baranda Martínez-Abasca

Diego Baranda Martínez-Abasca

Predoctoral researcher
Clinical Biochemistry, Drug Delivery & Therapy (CB-DDT)
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Belen Garcia Prats

Belen Garcia Prats

Research technician
Clinical Biochemistry, Drug Delivery & Therapy (CB-DDT)
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Clara Ramírez Serra

Clara Ramírez Serra

Predoctoral researcher
Clinical Biochemistry, Drug Delivery & Therapy (CB-DDT)
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Julia German Cortes

Julia German Cortes

Predoctoral researcher
Clinical Biochemistry, Drug Delivery & Therapy (CB-DDT)
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Laura García Latorre

Laura García Latorre

Research technician
Clinical Biochemistry, Drug Delivery & Therapy (CB-DDT)
Read more
Maria del Pilar Reimundo Diaz-Fierros

Maria del Pilar Reimundo Diaz-Fierros

Postdoctoral researcher
Clinical Biochemistry, Drug Delivery & Therapy (CB-DDT)
Read more
Diego Baranda Martínez-Abasca

Diego Baranda Martínez-Abasca

Predoctoral researcher
Clinical Biochemistry, Drug Delivery & Therapy (CB-DDT)
Read more
Belen Garcia Prats

Belen Garcia Prats

Research technician
Clinical Biochemistry, Drug Delivery & Therapy (CB-DDT)
Read more
Clara Ramírez Serra

Clara Ramírez Serra

Predoctoral researcher
Clinical Biochemistry, Drug Delivery & Therapy (CB-DDT)
Read more
Julia German Cortes

Julia German Cortes

Predoctoral researcher
Clinical Biochemistry, Drug Delivery & Therapy (CB-DDT)
Read more
Laura García Latorre

Laura García Latorre

Research technician
Clinical Biochemistry, Drug Delivery & Therapy (CB-DDT)
Read more

Research lines

Disseny, síntesi i caracterització de nanosistemes terapèutics biodegradables

IP: Disseny, síntesi i caracterització de nanosistemes terapèutics biodegradables

Estudi de les bases moleculars i cel·lulars del càncer

IP: Joaquin Seras Franzoso

Estudi i Millora del procés de fecundació in vitro

IP: Maria del Pilar Reimundo Diaz-Fierros

Obtenció i us de vesícules extracel·lulars com vehicles per proteïnes i biomolècules

IP: Obtenció i us de vesícules extracel·lulars com vehicles per proteïnes i biomolècules

Projects

Estudio multicéntrico de la reactividad de PSA de las vesículas extracelulares frente a inmunoensayos comerciales

IP: Roser Ferrer Costa
Collaborators: -
Funding agency: FUNDACIÓN JOSÉ LUIS CASTAÑO
Funding: 0.01
Reference: SECQ/FERRER/2023
Duration: 01/01/2024 - 31/12/2025

Cálculo de intervalos de referencia para magnitudes biológicas empleando un método indirecto

IP: Yolanda Villena Ortiz
Collaborators: -
Funding agency: FUNDACIÓN JOSÉ LUIS CASTAÑO
Funding: 6000
Reference: SEQC 001
Duration: 01/07/2023 - 01/07/2024

ARTEMIs: AcceleRating the Translation of virtual twins towards a pErsonalised Management of fatty lIver patients

IP: José Raul Herance Camacho
Collaborators: Beatriz Minguez Rosique, Clara Ramírez Serra, Cristina Gamez Cenzano, Juan Manuel Pericàs Pulido, Nuria Roson Gradaille, Andreea Ciudin Mihai, Alberto Roque Pérez, ARTEMIs: AcceleRating the Translation of virtual twins towards a pErsonalised Management of fatty lIver patients, Maria Nazarena Pizzi, Ramón Vilallonga Puy, Enrique Franky Vargas, Carolina Aparicio Gomez
Funding agency: EUROPEAN COMMISSION
Funding: 724000
Reference: ARTEMIS_HE-HLTH2023
Duration: 01/01/2024 - 31/12/2027

TACTIC: Explorando soluciones a los retos de salud mediante ciencia disruptiva, terapias avanzadas y medicina de sistemas

IP: Begoña Benito Villabriga
Collaborators: Carmen Escudero Iriarte, Laia Ventura i Expósito, Susana Otero Romero, Ignacio Ferreira González, José Antonio Barrabés Riu, Carlos Nos Llopis, Pablo Velasco Puyó, Jose Fernando Rodríguez Palomares, Sunny Malhotra Sareen, Belen Perez Dueñas, Jaume Sastre Garriga, Joan López Hellin, Antonia Sambola Ayala, Jordi Rio Izquierdo, Nuria Rivas Gandara, Jordi Perez Rodon, Aroa Soriano Fernández, Manuel Comabella Lopez, Antonio Rodríguez Sinovas, Gisela Teixido Tura, Antonia Pijuan Domenech, Roser Ferrer Costa, Joaquin Seras Franzoso, Carmen Tur Gomez, Maria Cristina Díaz de Heredia Rubio, Laia Yañez Bisbe, Maria Jose Pérez García, Miguel Segura Ginard, Diego Baranda Martínez-Abasca, Cristina Auger Acosta, Neus Bellera Gotarda, Teresa Macarulla Mercadé, Herena Eixarch Ahufinger, M Mar Mañu Pereira, Deborah Pareto Onghena, Lorena Valero Arrese, Aitor Uribarri Gonzalez, Jordi Bañeras Rius, Alex Rovira Cañellas, Mar Tintore Subirana, Bruno García del Blanco, Ana Vivancos Prellezo, Maria Teresa Salcedo Allende, Marisol Ruiz Meana, Ana Belén Méndez Fernández, Xavier Montalban Gairín, Simon Schwartz Navarro, Anna Llort Sales, Carmen Espejo Ruiz, Raquel Hladun Alvaro, Sandra Mancilla Zamora, Ana Zabalza de Torres, Javier Inserte Igual, Luciana Midaglia Fernandez, Elizabeth Pando Rau, Gabriela Guillén Burrieza, Ana Laura Cazurro Gutierrez, David Gómez Andrés, Alvaro Cobo Calvo, Alvaro Calabuig Goena, Joaquin Castillo Justribo, Lydia Dux-Santoy Hurtado, Lucas Moreno Martín-Retortillo, Andres Miguez Gonzalez, Josep Roma Castanyer, Laura Dos Subirá, Nicolás Miguel Fissolo, Maria Nazarena Pizzi, Paolo Giovanni Nuciforo, Tian Tian, Diana Fernandes de Rafael, Andrea Guala
Funding agency: Instituto de Salud Carlos III
Funding: 2494527.53
Reference: FORT23/00034
Duration: 01/01/2024 - 31/12/2027

Blog

News

The study results show that the local presence of IL-1β promotes the development of myeloid cells with an immunosuppressive function.

The grants promote new therapeutic strategies and diagnostic tools in highly complex tumors such as glioblastoma, triple-negative breast cancer, and endometrial cancer.

The project aims to improve prevention, diagnosis, and treatment through computational biomedicine, innovative therapies, and the transfer of knowledge into clinical practice.