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Clinical Biochemistry, Drug Delivery & Therapy

The Clinical Biochemistry, Drug Delivery & Therapy (CB-DDT) group arises from the merger of two VHIR groups, the Clinical Biochemistry group and the Drug Delivery and Targeting group, which they develop preclinical and clinical research in the diagnosis and therapy of different diseases.

With a direct link to the Clinical Biochemistry service of the Vall d'Hebron Hospital, our scope of action ranges from the analysis of massive data coming from the service, the development of diagnostic and prognostic biomarkers, evaluation of existing therapies and the development of new therapeutic strategies based on nanotechnology.

In terms of specific pathologies or indications, the group has an extensive track record in basic and applied research in cancer (new biomarkers, therapeutic targets and new treatments), metabolopathies (biomarkers and improvements in enzyme replacement therapy), kidney disease and liver disease.

Team

Marina Giralt Arnaiz

Marina Giralt Arnaiz

Predoctoral researcher
Clinical Biochemistry, Drug Delivery & Therapy (CB-DDT)
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Sandra Mancilla Zamora

Sandra Mancilla Zamora

Research technician
Clinical Biochemistry, Drug Delivery & Therapy (CB-DDT)
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Fernando Moreno Flores

Fernando Moreno Flores

Clinical Biochemistry, Drug Delivery & Therapy (CB-DDT)
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Ana Maria Casas Guerrero

Ana Maria Casas Guerrero

Research technician
Clinical Biochemistry, Drug Delivery & Therapy (CB-DDT)
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Andjelo Beletic

Andjelo Beletic

Predoctoral researcher
Clinical Biochemistry, Drug Delivery & Therapy (CB-DDT)
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Andrea Dorado Martín

Andrea Dorado Martín

Research technician
Clinical Biochemistry, Drug Delivery & Therapy (CB-DDT)
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Marina Giralt Arnaiz

Marina Giralt Arnaiz

Predoctoral researcher
Clinical Biochemistry, Drug Delivery & Therapy (CB-DDT)
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Sandra Mancilla Zamora

Sandra Mancilla Zamora

Research technician
Clinical Biochemistry, Drug Delivery & Therapy (CB-DDT)
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Fernando Moreno Flores

Fernando Moreno Flores

Clinical Biochemistry, Drug Delivery & Therapy (CB-DDT)
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Ana Maria Casas Guerrero

Ana Maria Casas Guerrero

Research technician
Clinical Biochemistry, Drug Delivery & Therapy (CB-DDT)
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Andjelo Beletic

Andjelo Beletic

Predoctoral researcher
Clinical Biochemistry, Drug Delivery & Therapy (CB-DDT)
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Andrea Dorado Martín

Andrea Dorado Martín

Research technician
Clinical Biochemistry, Drug Delivery & Therapy (CB-DDT)
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Projects

Efecto de la reposición de hierro sobre el remodelado ventricular después de la oclusi´pon coronaria transitoria en un modelo animal de ferropenia inducida por dieta

IP: José Antonio Barrabés Riu
Collaborators: Ignacio Ferreira González, David Beneitez Pastor, David Aluja Gonzalez, Sara Delgado Tomás, Laura Castellote Bellés, Javier Inserte Igual
Funding agency: -Sociedad Española de Cardiologia
Funding: 15000
Reference: SEC/FEC-INV-BAS 23/11
Duration: 01/01/2024 - 31/12/2027

Impact of stem-related tumor extracellular vesicles subsets in TNBC progression.

IP: Joaquin Seras Franzoso
Collaborators: Maria Fidel Lledó, Miriam Izquierdo Sans
Funding agency: Instituto de Salud Carlos III
Funding: 119567
Reference: FI23/00223
Duration: 15/01/2024 - 14/01/2028

Funciones Alternativas de la Sex Hormone-Binding Globulin: Mecanismos Moleculares y Papel en Fisiología y Fisiopatología

IP: David Martinez Selva
Collaborators: Maria Teresa Salcedo Allende, Lorena Ramos Pérez, Pablo Gabriel Medina, Pilar Costa Forner
Funding agency: Instituto de Salud Carlos III
Funding: 190000
Reference: PI23/00544
Duration: 01/01/2024 - 31/12/2026

Antimicrobianos nebulizados en receptores de trasplante pulmonar

IP: Ibai Los Arcos Bertiz
Collaborators: M Teresa Martin Gomez, Yolanda Villena Ortiz, Javier Gomis Rodriguez, Joan Gavaldà Santapau, Judith Sacanell Lacasa, Marta Zapata Ortega, Leire Sanchez Corujo
Funding agency: Instituto de Salud Carlos III
Funding: 37500
Reference: PI23/01467
Duration: 01/01/2024 - 31/12/2026

Blog

News

The study results show that the local presence of IL-1β promotes the development of myeloid cells with an immunosuppressive function.

The grants promote new therapeutic strategies and diagnostic tools in highly complex tumors such as glioblastoma, triple-negative breast cancer, and endometrial cancer.

The project aims to improve prevention, diagnosis, and treatment through computational biomedicine, innovative therapies, and the transfer of knowledge into clinical practice.