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Clinical Biochemistry, Drug Delivery & Therapy

The Clinical Biochemistry, Drug Delivery & Therapy (CB-DDT) group arises from the merger of two VHIR groups, the Clinical Biochemistry group and the Drug Delivery and Targeting group, which they develop preclinical and clinical research in the diagnosis and therapy of different diseases.

With a direct link to the Clinical Biochemistry service of the Vall d'Hebron Hospital, our scope of action ranges from the analysis of massive data coming from the service, the development of diagnostic and prognostic biomarkers, evaluation of existing therapies and the development of new therapeutic strategies based on nanotechnology.

In terms of specific pathologies or indications, the group has an extensive track record in basic and applied research in cancer (new biomarkers, therapeutic targets and new treatments), metabolopathies (biomarkers and improvements in enzyme replacement therapy), kidney disease and liver disease.

Team

Javier Esparcia Estrela

Javier Esparcia Estrela

Predoctoral researcher
Clinical Biochemistry, Drug Delivery & Therapy (CB-DDT)
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Joaquin Ruiz Altarejos

Joaquin Ruiz Altarejos

Research technician
Clinical Biochemistry, Drug Delivery & Therapy (CB-DDT)
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Luz María Cruz Carlos

Luz María Cruz Carlos

Clinical Biochemistry, Drug Delivery & Therapy (CB-DDT)
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Magalí Sureda de la Fuente

Magalí Sureda de la Fuente

Research technician
Clinical Biochemistry, Drug Delivery & Therapy (CB-DDT)
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Maria Fidel Lledò

Maria Fidel Lledò

Predoctoral researcher
Clinical Biochemistry, Drug Delivery & Therapy (CB-DDT)
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Mireia Salvadó Pau

Mireia Salvadó Pau

Postdoctoral researcher
Clinical Biochemistry, Drug Delivery & Therapy (CB-DDT)
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Javier Esparcia Estrela

Javier Esparcia Estrela

Predoctoral researcher
Clinical Biochemistry, Drug Delivery & Therapy (CB-DDT)
Read more
Joaquin Ruiz Altarejos

Joaquin Ruiz Altarejos

Research technician
Clinical Biochemistry, Drug Delivery & Therapy (CB-DDT)
Read more
Luz María Cruz Carlos

Luz María Cruz Carlos

Clinical Biochemistry, Drug Delivery & Therapy (CB-DDT)
Read more
Magalí Sureda de la Fuente

Magalí Sureda de la Fuente

Research technician
Clinical Biochemistry, Drug Delivery & Therapy (CB-DDT)
Read more
Maria Fidel Lledò

Maria Fidel Lledò

Predoctoral researcher
Clinical Biochemistry, Drug Delivery & Therapy (CB-DDT)
Read more
Mireia Salvadó Pau

Mireia Salvadó Pau

Postdoctoral researcher
Clinical Biochemistry, Drug Delivery & Therapy (CB-DDT)
Read more

Projects

HydroTheC

IP: -
Collaborators: Miriam Izquierdo Sans, Diana Fernandes de Rafael, Simon Schwartz Navarro
Funding agency: EUROPEAN COMMISSION
Funding: 221390.88
Reference: HYDROTEC_HE-MSCA-PF-GF2022
Duration: 01/01/2024 - 31/12/2026

Hacia un manejo clínico personalizado de pacientes oncológicos con fracaso renal agudo asociado a los immune-checkpoint inhibitors (ICIs)

IP: Maria Jose Soler Romeo
Collaborators: Hacia un manejo clínico personalizado de pacientes oncológicos con fracaso renal agudo asociado a los immune-checkpoint inhibit, Oriol Bestard Matamoros, Sheila Bermejo Garcia, Concepció Jacobs Cachá, Elena Isabel Crespo Gimeno, Sara Nuñez Delgado
Funding agency: Instituto de Salud Carlos III
Funding: 246840
Reference: AC22/00029
Duration: 01/01/2023 - 31/12/2025

Bioquímica Clínica, Vehiculització de Fàrmacs i Teràpia (Clinical Biochemistry, Drug Delivery & Therapy, CB-DDT)

IP: -
Collaborators: José Antonio Arranz Amo, Raquel Barquin Del Pino, Laura Conesa Milian, Clara Ramírez Serra, Yolanda Villena Ortiz, Joan López Hellin, Albert Blanco Grau, Roser Ferrer Costa, Joaquin Seras Franzoso, Diego Baranda Martínez-Abasca, Laura Castillo Ribelles, Clara Carnicer Cáceres, Marina Giralt Arnaiz, Ana Gomez Garcia, Simon Schwartz Navarro, Pablo Gabriel Medina, Bioquímica Clínica, Vehiculització de Fàrmacs i Teràpia (Clinical Biochemistry, Drug Delivery & Therapy, CB-DDT), Bioquímica Clínica, Vehiculització de Fàrmacs i Teràpia (Clinical Biochemistry, Drug Delivery & Therapy, CB-DDT), Laura Castellote Bellés, Daniel Bravo Nieto, Luz María Cruz Carlos, Clara Sanz Gea, Alba Estela García Fernández, Maria del Pilar Reimundo Diaz-Fierros, Belen Garcia Prats, Noelia Díaz Troyano, JAUME VIMA BOFARULL, Bioquímica Clínica, Vehiculització de Fàrmacs i Teràpia (Clinical Biochemistry, Drug Delivery & Therapy, CB-DDT), Diana Fernandes de Rafael, Maria Francesca Cortese, Sandra Mancilla Zamora
Funding agency: Agència Gestió Ajuts Universitaris i de Recerca
Funding: 60000
Reference: 2021 SGR 01173
Duration: 01/01/2022 - 30/06/2025

Nefrologia i Trasplantament Renal

IP: Oriol Bestard Matamoros
Collaborators: Marina Lopez Martinez, Francesc Moreso Mateos, Natalia Ramos Terrades, Maria Jose Soler Romeo, Joana Sellarés Roig, Pamela Dominguez Baez, Irene Agraz Pamplona, Sheila Bermejo Garcia, Mariona Juvé Torres, Irina Betsabe Torres Rodriguez, Concepció Jacobs Cachá, Elena Isabel Crespo Gimeno, Laura Donadeu Casassas, Carmen Llorens Cebriá, Manel Perelló Carrascosa, Maria Antonia Emilia Meneghini
Funding agency: Agència Gestió Ajuts Universitaris i de Recerca
Funding: 40000
Reference: 2021 SGR 00883
Duration: 01/01/2022 - 30/06/2025

Blog

News

The study results show that the local presence of IL-1β promotes the development of myeloid cells with an immunosuppressive function.

The grants promote new therapeutic strategies and diagnostic tools in highly complex tumors such as glioblastoma, triple-negative breast cancer, and endometrial cancer.

The project aims to improve prevention, diagnosis, and treatment through computational biomedicine, innovative therapies, and the transfer of knowledge into clinical practice.