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Clinical Biochemistry, Drug Delivery & Therapy

The Clinical Biochemistry, Drug Delivery & Therapy (CB-DDT) group arises from the merger of two VHIR groups, the Clinical Biochemistry group and the Drug Delivery and Targeting group, which they develop preclinical and clinical research in the diagnosis and therapy of different diseases.

With a direct link to the Clinical Biochemistry service of the Vall d'Hebron Hospital, our scope of action ranges from the analysis of massive data coming from the service, the development of diagnostic and prognostic biomarkers, evaluation of existing therapies and the development of new therapeutic strategies based on nanotechnology.

In terms of specific pathologies or indications, the group has an extensive track record in basic and applied research in cancer (new biomarkers, therapeutic targets and new treatments), metabolopathies (biomarkers and improvements in enzyme replacement therapy), kidney disease and liver disease.

Team

Laura Conesa Milian

Laura Conesa Milian

Postdoctoral researcher
Clinical Biochemistry, Drug Delivery & Therapy (CB-DDT)
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Luisa Maria Martinez Sánchez

Luisa Maria Martinez Sánchez

Research assistant
Clinical Biochemistry, Drug Delivery & Therapy (CB-DDT)
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Maria del Carmen Sanchez  Valcarcel

Maria del Carmen Sanchez Valcarcel

Research assistant
Clinical Biochemistry, Drug Delivery & Therapy (CB-DDT)
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Mireia Benito Jimenez

Mireia Benito Jimenez

Research assistant
Clinical Biochemistry, Drug Delivery & Therapy (CB-DDT)
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Mª Pilar Felipe Fernandez

Mª Pilar Felipe Fernandez

Predoctoral researcher
Clinical Biochemistry, Drug Delivery & Therapy (CB-DDT)
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Mª Teresa Gené Juyent

Mª Teresa Gené Juyent

Predoctoral researcher
Clinical Biochemistry, Drug Delivery & Therapy (CB-DDT)
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Laura Conesa Milian

Laura Conesa Milian

Postdoctoral researcher
Clinical Biochemistry, Drug Delivery & Therapy (CB-DDT)
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Luisa Maria Martinez Sánchez

Luisa Maria Martinez Sánchez

Research assistant
Clinical Biochemistry, Drug Delivery & Therapy (CB-DDT)
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Maria del Carmen Sanchez  Valcarcel

Maria del Carmen Sanchez Valcarcel

Research assistant
Clinical Biochemistry, Drug Delivery & Therapy (CB-DDT)
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Mireia Benito Jimenez

Mireia Benito Jimenez

Research assistant
Clinical Biochemistry, Drug Delivery & Therapy (CB-DDT)
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Mª Pilar Felipe Fernandez

Mª Pilar Felipe Fernandez

Predoctoral researcher
Clinical Biochemistry, Drug Delivery & Therapy (CB-DDT)
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Mª Teresa Gené Juyent

Mª Teresa Gené Juyent

Predoctoral researcher
Clinical Biochemistry, Drug Delivery & Therapy (CB-DDT)
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Projects

Deciphering the Mechanisms of PLA2R-specific B-cell Autoimmunity in Primary Membranous Nephropathy (PMN)(BCELL-MEM)

IP: Maria Jose Soler Romeo
Collaborators: Laura Donadeu Casassas, Oriol Bestard Matamoros, Elena Isabel Crespo Gimeno, Concepció Jacobs Cachá
Funding agency: Fundació La Marató de TV3
Funding: 199935.54
Reference: 202037-31
Duration: 01/06/2021 - 31/12/2024

Role of Apolipoprotein A-Ib in the idiopathic nephrotic syndrome

IP: Concepció Jacobs Cachá
Collaborators: -
Funding agency: Fundació La Marató de TV3
Funding: 199966.31
Reference: 202017/10
Duration: 30/03/2021 - 31/12/2024

MIMIC-KeY - A KEY TO THE RATIONAL DESIGN OF EXTRACELLULAR VESICLES-MIMICKING NANOPARTICLES.

IP: Simon Schwartz Navarro
Collaborators: Joaquin Seras Franzoso, Guillem Pintos Morell, MIMIC-KeY - A KEY TO THE RATIONAL DESIGN OF EXTRACELLULAR VESICLES-MIMICKING NANOPARTICLES., MIMIC-KeY - A KEY TO THE RATIONAL DESIGN OF EXTRACELLULAR VESICLES-MIMICKING NANOPARTICLES.
Funding agency: EUROPEAN COMMISSION
Funding: 457250
Reference: MIMIC-KEY_H2020-FETPROACT-2020
Duration: 01/06/2021 - 30/11/2025

The interplay between ACE2 and AXL systems to predict COVID-19 disease severity and outcomes

IP: Maria Jose Soler Romeo
Collaborators: Concepció Jacobs Cachá
Funding agency: Fundació La Marató de TV3
Funding: 154125
Reference: 202133-30
Duration: 23/09/2021 - 22/09/2024

Blog

News

The study results show that the local presence of IL-1β promotes the development of myeloid cells with an immunosuppressive function.

The grants promote new therapeutic strategies and diagnostic tools in highly complex tumors such as glioblastoma, triple-negative breast cancer, and endometrial cancer.

The project aims to improve prevention, diagnosis, and treatment through computational biomedicine, innovative therapies, and the transfer of knowledge into clinical practice.