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Clinical Biochemistry, Drug Delivery & Therapy

The Clinical Biochemistry, Drug Delivery & Therapy (CB-DDT) group arises from the merger of two VHIR groups, the Clinical Biochemistry group and the Drug Delivery and Targeting group, which they develop preclinical and clinical research in the diagnosis and therapy of different diseases.

With a direct link to the Clinical Biochemistry service of the Vall d'Hebron Hospital, our scope of action ranges from the analysis of massive data coming from the service, the development of diagnostic and prognostic biomarkers, evaluation of existing therapies and the development of new therapeutic strategies based on nanotechnology.

In terms of specific pathologies or indications, the group has an extensive track record in basic and applied research in cancer (new biomarkers, therapeutic targets and new treatments), metabolopathies (biomarkers and improvements in enzyme replacement therapy), kidney disease and liver disease.

Team

Noelia Díaz Troyano

Noelia Díaz Troyano

Clinical Biochemistry, Drug Delivery & Therapy (CB-DDT)
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Pablo Gabriel Medina

Pablo Gabriel Medina

Predoctoral researcher
Clinical Biochemistry, Drug Delivery & Therapy (CB-DDT)
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Pilar Bonet Palomares

Pilar Bonet Palomares

Research technician
Clinical Biochemistry, Drug Delivery & Therapy (CB-DDT)
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Raquel  Barquin Del Pino

Raquel Barquin Del Pino

Clinical Biochemistry, Drug Delivery & Therapy (CB-DDT)
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Yolanda Villena Ortiz

Yolanda Villena Ortiz

Main researcher
Clinical Biochemistry, Drug Delivery & Therapy (CB-DDT)
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Noelia Díaz Troyano

Noelia Díaz Troyano

Clinical Biochemistry, Drug Delivery & Therapy (CB-DDT)
Read more
Pablo Gabriel Medina

Pablo Gabriel Medina

Predoctoral researcher
Clinical Biochemistry, Drug Delivery & Therapy (CB-DDT)
Read more
Pilar Bonet Palomares

Pilar Bonet Palomares

Research technician
Clinical Biochemistry, Drug Delivery & Therapy (CB-DDT)
Read more
Raquel  Barquin Del Pino

Raquel Barquin Del Pino

Clinical Biochemistry, Drug Delivery & Therapy (CB-DDT)
Read more
Yolanda Villena Ortiz

Yolanda Villena Ortiz

Main researcher
Clinical Biochemistry, Drug Delivery & Therapy (CB-DDT)
Read more

Projects

Impact of COVID-19 on male reproductive health

IP: Melchor Carbonell Socias
Collaborators: Julio Herrero García, Nerea Maiz Elizaran, Anna Suy Franch, Maria del Pilar Reimundo Diaz-Fierros
Funding agency: Fundació La Marató de TV3
Funding: 49988.75
Reference: 202128-32
Duration: 20/10/2021 - 19/10/2024

Vesículas extracelulares para el tratamiento de enfermeades lisosomales (Título provisional)

IP: -
Collaborators: Laura García Latorre, Guillem Pintos Morell, Sandra Mancilla Zamora, Vesículas extracelulares para el tratamiento de enfermeades lisosomales (Título provisional), Vesículas extracelulares para el tratamiento de enfermeades lisosomales (Título provisional), Vesículas extracelulares para el tratamiento de enfermeades lisosomales (Título provisional), Vesículas extracelulares para el tratamiento de enfermeades lisosomales (Título provisional), Vesículas extracelulares para el tratamiento de enfermeades lisosomales (Título provisional), Vesículas extracelulares para el tratamiento de enfermeades lisosomales (Título provisional), Vesículas extracelulares para el tratamiento de enfermeades lisosomales (Título provisional), Vesículas extracelulares para el tratamiento de enfermeades lisosomales (Título provisional), Vesículas extracelulares para el tratamiento de enfermeades lisosomales (Título provisional), Vesículas extracelulares para el tratamiento de enfermeades lisosomales (Título provisional), Vesículas extracelulares para el tratamiento de enfermeades lisosomales (Título provisional), Vesículas extracelulares para el tratamiento de enfermeades lisosomales (Título provisional), Vesículas extracelulares para el tratamiento de enfermeades lisosomales (Título provisional), Vesículas extracelulares para el tratamiento de enfermeades lisosomales (Título provisional)
Funding agency: Instituto de Salud Carlos III
Funding: 153670
Reference: PI21/00936
Duration: 01/01/2022 - 30/06/2025

Desentrañando las vías protectoras de los SGLT2i y GLP-1RA en la enfermedad renal diabética: papel de las proteínas adaptadoras MAP17 y D-AKAP-2 en ratones db/db y organoides renales humanos.

IP: Maria Jose Soler Romeo
Collaborators: Mario Alonso Narvaez Barros, Pamela Dominguez Baez, Sheila Bermejo Garcia, Alejandra Planas Vilaseca, Concepció Jacobs Cachá, Juan Carlos León Román, Irene Martinez Diaz
Funding agency: Instituto de Salud Carlos III
Funding: 122210
Reference: PI21/01292
Duration: 01/01/2022 - 30/06/2026

Blog

News

The study results show that the local presence of IL-1β promotes the development of myeloid cells with an immunosuppressive function.

The grants promote new therapeutic strategies and diagnostic tools in highly complex tumors such as glioblastoma, triple-negative breast cancer, and endometrial cancer.

The project aims to improve prevention, diagnosis, and treatment through computational biomedicine, innovative therapies, and the transfer of knowledge into clinical practice.