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Clinical Biochemistry, Drug Delivery & Therapy

The Clinical Biochemistry, Drug Delivery & Therapy (CB-DDT) group arises from the merger of two VHIR groups, the Clinical Biochemistry group and the Drug Delivery and Targeting group, which they develop preclinical and clinical research in the diagnosis and therapy of different diseases.

With a direct link to the Clinical Biochemistry service of the Vall d'Hebron Hospital, our scope of action ranges from the analysis of massive data coming from the service, the development of diagnostic and prognostic biomarkers, evaluation of existing therapies and the development of new therapeutic strategies based on nanotechnology.

In terms of specific pathologies or indications, the group has an extensive track record in basic and applied research in cancer (new biomarkers, therapeutic targets and new treatments), metabolopathies (biomarkers and improvements in enzyme replacement therapy), kidney disease and liver disease.

Team

Mª Pilar Felipe Fernandez

Mª Pilar Felipe Fernandez

Predoctoral researcher
Clinical Biochemistry, Drug Delivery & Therapy (CB-DDT)
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Mª Teresa Gené Juyent

Mª Teresa Gené Juyent

Predoctoral researcher
Clinical Biochemistry, Drug Delivery & Therapy (CB-DDT)
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Noelia Díaz Troyano

Noelia Díaz Troyano

Clinical Biochemistry, Drug Delivery & Therapy (CB-DDT)
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Pablo Gabriel Medina

Pablo Gabriel Medina

Predoctoral researcher
Clinical Biochemistry, Drug Delivery & Therapy (CB-DDT)
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Pilar Bonet Palomares

Pilar Bonet Palomares

Research technician
Clinical Biochemistry, Drug Delivery & Therapy (CB-DDT)
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Raquel  Barquin Del Pino

Raquel Barquin Del Pino

Clinical Biochemistry, Drug Delivery & Therapy (CB-DDT)
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Mª Pilar Felipe Fernandez

Mª Pilar Felipe Fernandez

Predoctoral researcher
Clinical Biochemistry, Drug Delivery & Therapy (CB-DDT)
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Mª Teresa Gené Juyent

Mª Teresa Gené Juyent

Predoctoral researcher
Clinical Biochemistry, Drug Delivery & Therapy (CB-DDT)
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Noelia Díaz Troyano

Noelia Díaz Troyano

Clinical Biochemistry, Drug Delivery & Therapy (CB-DDT)
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Pablo Gabriel Medina

Pablo Gabriel Medina

Predoctoral researcher
Clinical Biochemistry, Drug Delivery & Therapy (CB-DDT)
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Pilar Bonet Palomares

Pilar Bonet Palomares

Research technician
Clinical Biochemistry, Drug Delivery & Therapy (CB-DDT)
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Raquel  Barquin Del Pino

Raquel Barquin Del Pino

Clinical Biochemistry, Drug Delivery & Therapy (CB-DDT)
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Projects

Vesículas extracelulares para el tratamiento de enfermeades lisosomales (Título provisional)

IP: Ibane Abasolo Olaortua
Collaborators: Laura García Latorre, Guillem Pintos Morell, Sandra Mancilla Zamora, Zamira Vanessa Diaz Riascos, Marc Miquel Moltó Abad, Zamira Vanessa Diaz Riascos, Zamira Vanessa Diaz Riascos
Funding agency: Instituto de Salud Carlos III
Funding: 153670
Reference: PI21/00936
Duration: 01/01/2022 - 30/06/2025

Desentrañando las vías protectoras de los SGLT2i y GLP-1RA en la enfermedad renal diabética: papel de las proteínas adaptadoras MAP17 y D-AKAP-2 en ratones db/db y organoides renales humanos.

IP: Maria Jose Soler Romeo
Collaborators: Mario Alonso Narvaez Barros, Pamela Dominguez Baez, Sheila Bermejo Garcia, Alejandra Planas Vilaseca, Concepció Jacobs Cachá, Juan Carlos León Román, Irene Martinez Diaz
Funding agency: Instituto de Salud Carlos III
Funding: 122210
Reference: PI21/01292
Duration: 01/01/2022 - 30/06/2026

Publications

A new era for Advances in Laboratory Medicine.

PMID: 38075176
Journal: Advances in Laboratory Medicine
Year: 2023
Reference: Adv Lab Med. 2023 Sep 13;4(3):203-204. doi: 10.1515/almed-2023-0116. eCollection 2023 Sep.
Impact factor:
Publication type: Editorail in international publication
Authors: Arribas, Ignacio; Fernandez-Calle, Pilar; Ferrer-Costa, Roser; Gonzalez, Alvaro; Jimenez, Wladimiro et al.
DOI: 10.1515/almed-2023-0116

[Not Available].

PMID: 38075162
Journal: Advances in Laboratory Medicine
Year: 2023
Reference: Adv Lab Med. 2023 Sep 8;4(3):205-206. doi: 10.1515/almed-2023-0113. eCollection 2023 Sep.
Impact factor:
Publication type: Editorial in national publication
Authors: Arribas, Ignacio; Fernandez-Calle, Pilar; Ferrer-Costa, Roser; Gonzalez, Alvaro; Jimenez, Wladimiro et al.
DOI: 10.1515/almed-2023-0113

Community-based screening enhances hepatitis B virus linkage to care among West African migrants in Spain.

PMID: 38097770
Journal: Communications medicine
Year: 2023
Reference: Commun Med (Lond). 2023 Dec 14;3(1):182. doi: 10.1038/s43856-023-00420-8.
Impact factor:
Publication type: Paper in international publication
Authors: Araujo, Silvia G; Buti, Maria; Fernandez, Emma; Forns, Xavier; Lazarus, Jeffrey V; Lens, Sabela; MacKinnon, Marina; Martro, Elisa; Nomah, Daniel K; Nunez, Carmen Lopez et al.
DOI: 10.1038/s43856-023-00420-8

Assessing the rate of non-linkage to care and identifying barriers in individuals living with hepatitis B. Results of the LINK-B study.

PMID: 38111084
Journal: LIVER INTERNATIONAL
Year: 2023
Reference: Liver Int. 2023 Dec 18. doi: 10.1111/liv.15814.
Impact factor:
Publication type: Paper in international publication
Authors: Barreira-Diaz, Ana; Buti, Maria; Esteban, Rafael; Feliu-Prius, Anna; Palom, Adriana; Rando, Ariadna; Riveiro-Barciela, Mar; Rodriguez-Frias, Francisco; Ruiz-Cobo, Juan C; Vargas-Accarino, Elena et al.
DOI: 10.1111/liv.15814

Blog

News

Researchers from all over Europe gathered to kick off the SPM4.0 project, an innovative Marie Curie Skłodowska (MSCA-DN) doctoral network that promotes the development of autonomous Scanning Probe Microscopy with AI.

The meeting was an opportunity to get to know projects from both institutions and to promote interaction between professionals.

The European Rare Diseases Research Alliance (ERDERA) kicked off this September, with an estimated budget of 380 million euros and the aim of improving the lives of 30 million rare disease patients in Europe and beyond.