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Clinical Neuroimmunology

The group of Clinical Neuroimmunology - Centre d'Esclerosi Múltiple de Catalunya (Cemcat) at the Vall d'Hebron Institut de Recerca (VHIR) is a multidisciplinary group dedicated to clinical assistance, physical and cognitive rehabilitation, and clinical and basic research on multiple sclerosis (MS). Cemcat is a national but also an international reference center in the clinical assistance of MS patients. The research performed in the group is divided and further combined in clinical and basic research. In addition, basic research has a marked translational character since the ultimate goal of the group is to improve the quality of life of patients suffering from MS, through in-depth knowledge of the pathogenic mechanisms of the disease and the development of new and more effective therapeutic approaches. 

Team

Alarcon Gimenez, Irene

Alarcon Gimenez, Irene

Clinical Neuroimmunology
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Andres Miguez Gonzalez

Andres Miguez Gonzalez

Postdoctoral researcher
Clinical Neuroimmunology
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Andreu Vilaseca Jolonch

Andreu Vilaseca Jolonch

Predoctoral researcher
Clinical Neuroimmunology
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Ariño  Rodríguez, Helena

Ariño Rodríguez, Helena

Postdoctoral researcher
Clinical Neuroimmunology
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Arnau Hervera Abad

Arnau Hervera Abad

Main researcher
Clinical Neuroimmunology
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Aroca Alsina, Montserrat

Aroca Alsina, Montserrat

Research assistant
Clinical Neuroimmunology
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Alarcon Gimenez, Irene

Alarcon Gimenez, Irene

Clinical Neuroimmunology
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Andres Miguez Gonzalez

Andres Miguez Gonzalez

Postdoctoral researcher
Clinical Neuroimmunology
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Andreu Vilaseca Jolonch

Andreu Vilaseca Jolonch

Predoctoral researcher
Clinical Neuroimmunology
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Ariño  Rodríguez, Helena

Ariño Rodríguez, Helena

Postdoctoral researcher
Clinical Neuroimmunology
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Arnau Hervera Abad

Arnau Hervera Abad

Main researcher
Clinical Neuroimmunology
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Aroca Alsina, Montserrat

Aroca Alsina, Montserrat

Research assistant
Clinical Neuroimmunology
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Projects

Red de investigación en inflammasoma y piroptosis en enfermedades crónicas y cáncer

IP: Manuel Comabella Lopez
Collaborators: -
Funding agency: Ministerio de Ciencia e Innovación-MICINN
Funding: 0.01
Reference: RED2022-134511-T
Duration: 01/06/2023 - 31/05/2025

Ministerio de Ciencia

Beca VHIR PhD

IP: Manuel Comabella Lopez
Collaborators: Sira Rodrigo Bosch, Laia Perez Lasarte, Elisa Marín Ordovás, Miriam Izquierdo Sans
Funding agency: Fundació Institut de Recerca HUVH
Funding: 69188.74
Reference: VPHD/ELISA_M
Duration: 01/04/2023 - 31/03/2026

INHIBICION DE LA HDAC3 COMO TERAPIA PARA LESIONES MEDULARES Y ENFERMEDADES AUTOIMMUNES DEMIELINIZANTES

IP: Arnau Hervera Abad
Collaborators: -
Funding agency: Ministerio de Ciencia e Innovación-MICINN
Funding: 66612.39
Reference: PID2020-119769RA-I00
Duration: 01/01/2023 - 31/08/2024

Ministerio de Ciencia

x

IP: Xavier Montalban Gairín
Collaborators: Arnau Hervera Abad, Miriam Izquierdo Sans
Funding agency: Ministerio de Ciencia e Innovación-MICINN
Funding: 236350
Reference: RYC2021-033528-I
Duration: 01/01/2023 - 31/12/2027

Ministerio de Ciencia

Publications

ECTRIMS/EAN consensus on vaccination in people with multiple sclerosis: Improving immunization strategies in the era of highly active immunotherapeutic drugs.

PMID: 37293841
Journal: Multiple Sclerosis Journal
Year: 2023
Reference: Mult Scler. 2023 Jun 9:13524585231168043. doi: 10.1177/13524585231168043.
Impact factor:
Publication type: Review in international publication
Authors: Amato, Maria Pia; Campins, Magda; Farez, Mauricio; Filippi, Massimo; Hacohen, Yael; Hemmer, Bernhard; Juuti, Rosa; Lebrun-Frenay, Christine; Magyari, Melinda; Oreja-Guevara, Celia et al.
DOI: 10.1177/13524585231168043

Diffusion-based structural connectivity patterns of multiple sclerosis phenotypes.

PMID: 37321841
Journal: JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY
Year: 2023
Reference: J Neurol Neurosurg Psychiatry. 2023 Jun 15:jnnp-2023-331531. doi: 10.1136/jnnp-2023-331531.
Impact factor:
Publication type: Paper in international publication
Authors: Alba-Arbalat, Salut; Barkhof, Frederik; Bellenberg, Barbara; Blanco, Yolanda; Calvi, Alberto; Ciccarelli, Olga; Collorone, Sara; Dineen, Robert A; Filippi, Massimo; Fleischer, Vinzenz et al.
DOI: 10.1136/jnnp-2023-331531

A plain language summary of what clinical studies can tell us about the safety of evobrutinib - a potential treatment for multiple sclerosis.

PMID: 37345645
Journal: Neurodegenerative disease management
Year: 2023
Reference: Neurodegener Dis Manag. 2023 Jun 22. doi: 10.2217/nmt-2023-0003.
Impact factor:
Publication type: Review in international publication
Authors: Bolay, Claire Le; Genovese, Mark C; Guehring, Hans; Kao, Amy H; Montalban, Xavier; Parsons-Rich, Dana; Tomic, Davorka; Wallace, Daniel et al.
DOI: 10.2217/nmt-2023-0003

Accuracy of a Smartwatch to Assess Heart Rate Monitoring and Atrial Fibrillation in Stroke Patients.

PMID: 37430546
Journal: SENSORS
Year: 2023
Reference: Sensors (Basel). 2023 May 10;23(10):4632. doi: 10.3390/s23104632.
Impact factor:
Publication type: Paper in international publication
Authors: Alvarez-Sabin, Jose; Bashir, Saima; Duran, Laura; Francisco, Jaume; Juega, Jesus; Meza, Claudia; Molina, Carlos; Pagola, Jorge; Rodriguez, Maite; Santos, Alba et al.
DOI: 10.3390/s23104632

Humoral and Cellular Responses to SARS-CoV-2 in Convalescent COVID-19 Patients With Multiple Sclerosis.

PMID: 35105687
Journal: Neurology-Neuroimmunology & Neuroinflammation
Year: 2022
Reference: Neurol Neuroimmunol Neuroinflamm. 2022 Feb 1;9(2). pii: 9/2/e1143. doi: 10.1212/NXI.0000000000001143. Print 2022 Mar.
Impact factor: 8.485
Publication type: Paper in international publication
Authors: Arrambide, Georgina; Zabalza, Ana; Nos, Carlos; Sastre-Garriga, Jaume; Tintore, Mar; Montalban, Xavier; Comabella, Manuel; Espejo, Carmen; Castillo, Joaquin; Otero-Romero, Susana et al.
DOI: 10.1212/NXI.0000000000001143

Neurotoxicity-associated sinus bradycardia after chimeric antigen receptor T-cell therapy.

PMID: 35139240
Journal: HEMATOLOGICAL ONCOLOGY
Year: 2022
Reference: Hematol Oncol. 2022 Feb 9. doi: 10.1002/hon.2976.
Impact factor: 5.271
Publication type: Letter or abstract
Authors: Barba, Pere; Tintore, Mar; Bosch, Francesc; Cabirta, Alba; Catala, Eva; Iacoboni, Gloria; Vidal-Jordana, Angela; Oristrell, Gerard; Carpio, Cecilia; Vilaseca, Andreu et al.
DOI: 10.1002/hon.2976

Risk factors of severe COVID-19 in people with multiple sclerosis : A systematic review and meta-analysis.

PMID: 34836608
Journal: REVUE NEUROLOGIQUE
Year: 2022
Reference: Rev Neurol (Paris). 2022 Jan-Feb;178(1-2):121-128. doi: 10.1016/j.neurol.2021.10.003. Epub 2021 Nov 4.
Impact factor: 2.607
Publication type: Review in international publication
Authors: Zabalza, A; Mahdavi, S; Baratian, M; Sedaghat, N; Sepulveda, M; Blanco, Y; Salari, M; Akhavan Sigari, A; Etemadifar, M; Nouri, H et al.
DOI: 10.1016/j.neurol.2021.10.003

Treatment satisfaction, safety, and tolerability of cladribine tablets in patients with highly active relapsing multiple sclerosis: CLARIFY-MS study 6-month interim analysis.

PMID: 35158476
Journal: Multiple Sclerosis and Related Disorders
Year: 2022
Reference: Mult Scler Relat Disord. 2022 Jan;57:103385. doi: 10.1016/j.msard.2021.103385. Epub 2021 Nov 9.
Impact factor: 4.339
Publication type: Paper in international publication
Authors: Hupperts, Raymond; Langdon, Dawn; Solari, Alessandra; Piehl, Fredrik; Lechner-Scott, Jeannette; Montalban, Xavier; Selmaj, Krzysztof; Valis, Martin; Rejdak, Konrad; Havrdova, Eva K et al.
DOI: 10.1016/j.msard.2021.103385

Quantification of Cervical Cord Cross-Sectional Area: Which Acquisition, Vertebra Level, and Analysis Software? A Multicenter Repeatability Study on a Traveling Healthy Volunteer.

PMID: 34421797
Journal: Frontiers in Neurology
Year: 2021
Reference: Front Neurol. 2021 Aug 4;12:693333. doi: 10.3389/fneur.2021.693333. eCollection 2021.
Impact factor: 4.003
Publication type: Paper in international publication
Authors: Gandini Wheeler-Kingshott, Claudia A M, Kappos, Ludwig, Rocca, Maria A, Filippi, Massimo, Yiannakas, Marios, Barkhof, Frederik, Vrenken, Hugo, Sastre-Garriga, Jaume, Rovira, Alex, Brouwer, Iman et al.
DOI: 10.3389/fneur.2021.693333

Myelin-oligodendrocyte glycoprotein antibody-associated disease.

PMID: 34418402
Journal: LANCET NEUROLOGY
Year: 2021
Reference: Lancet Neurol. 2021 Sep;20(9):762-772. doi: 10.1016/S1474-4422(21)00218-0.
Impact factor: 44.182
Publication type: Review in international publication
Authors: Linington, Christopher, Meinl, Edgar, Palace, Jacqueline, Paul, Friedemann, Petzold, Axel, Pittock, Sean, Reindl, Markus, Sato, Douglas Kazutoshi, Selmaj, Krzysztof, Siva, Aksel et al.
DOI: 10.1016/S1474-4422(21)00218-0

Open-access quantitative MRI data of the spinal cord and reproducibility across participants, sites and manufacturers.

PMID: 34400655
Journal: Scientific Data
Year: 2021
Reference: Sci Data. 2021 Aug 16;8(1):219. doi: 10.1038/s41597-021-00941-8.
Impact factor: 6.444
Publication type: Paper in international publication
Authors: Lagana, Maria Marcella, Cohen-Adad, Julien, Alonso-Ortiz, Eva, Abramovic, Mihael, Arneitz, Carina, Atcheson, Nicole, Gros, Charley, Grussu, Francesco, Hagiwara, Akifumi, Henry, Pierre-Gilles et al.
DOI: 10.1038/s41597-021-00941-8

Generic acquisition protocol for quantitative MRI of the spinal cord.

PMID: 34400839
Journal: Nature protocols
Year: 2021
Reference: Nat Protoc. 2021 Oct;16(10):4611-4632. doi: 10.1038/s41596-021-00588-0. Epub 2021 Aug 16.
Impact factor: 0
Publication type: Review in international publication
Authors: Kinany, Nawal, Freund, Patrick, Finsterbusch, Jurgen, Foias, Alexandru, Fratini, Michela, Fukunaga, Issei, Wheeler-Kingshott, Claudia A M Gandini, Germani, Giancarlo, Gilbert, Guillaume, Giove, Federico et al.
DOI: 10.1038/s41596-021-00588-0

COVID-19 and Stroke: Incidence and Etiological Description in a High-Volume Center.

PMID: 33066917
Journal: Journal of Stroke & Cerebrovascular Diseases
Year: 2020
Reference: J Stroke Cerebrovasc Dis. 2020 Nov;29(11):105225. doi: 10.1016/j.jstrokecerebrovasdis.2020.105225. Epub 2020 Aug 5.
Impact factor: 1.787
Publication type: Paper in international publication
Authors: Ribo, Marc, Molina, Carlos A, Tomasello, Alejandro, Rubiera, Marta, Requena, Manuel, Muchada, Marian, Garcia-Tornel, Alvaro, Deck, Matias, Juega, Jesus, Boned, Sandra et al.
DOI: 10.1016/j.jstrokecerebrovasdis.2020.105225

Purified IgG from aquaporin-4 neuromyelitis optica spectrum disorder patients alters blood-brain barrier permeability.

PMID: 32881954
Journal: PLoS One
Year: 2020
Reference: PLoS One. 2020 Sep 3;15(9):e0238301. doi: 10.1371/journal.pone.0238301. eCollection 2020.
Impact factor: 2.74
Publication type: Paper in international publication
Authors: Cobo-Calvo, Alvaro, Ruiz, Anne, Richard, Chloe, Blondel, Sandrine, Cavagna, Sylvie, Strazielle, Nathalie, Ghersi-Egea, Jean-Francois, Giraudon, Pascale, Marignier, Romain et al.
DOI: 10.1371/journal.pone.0238301

Relationship of estrogen synthesis capacity in the brain with obesity and self-control in men and women.

PMID: 32868418
Journal: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Year: 2020
Reference: Proc Natl Acad Sci U S A. 2020 Sep 15;117(37):22962-22966. doi: 10.1073/pnas.2006117117. Epub 2020 Aug 31.
Impact factor: 9.412
Publication type: Paper in international publication
Authors: Biegon, Anat, Alia-Klein, Nelly, Alexoff, David L, Fowler, Joanna S, Kim, Sung Won, Logan, Jean, Pareto, Deborah, Preston-Campbell, Rebecca, Wang, Gene-Jack, Hildebrandt, Tom et al.
DOI: 10.1073/pnas.2006117117

Using smartphones and wearable devices to monitor behavioural changes during COVID-19.

PMID: 32877352
Journal: JOURNAL OF MEDICAL INTERNET RESEARCH
Year: 2020
Reference: J Med Internet Res. 2020 Sep 25;22(9):e19992. doi: 10.2196/19992.
Impact factor: 5.034
Publication type: Paper in international publication
Authors: Lamers, Femke, Siddi, Sara, Haro, Josep Maria, Myin-Germeys, Inez, Rintala, Aki, Wykes, Til, Narayan, Vaibhav A, Comi, Giancarlo, Hotopf, Matthew, Dobson, Richard Jb et al.
DOI: 10.2196/19992

Procedural approaches and angiographic signs predicting first-pass recanalization in patients treated with mechanical thrombectomy for acute ischaemic stroke.

PMID: 31072248
Journal: INTERVENTIONAL NEURORADIOLOGY
Year: 2019
Reference: Interv Neuroradiol. 2019 Oct;25(5):491-496. doi: 10.1177/1591019919847623. Epub 2019 May 9.
Impact factor: 1.45
Publication type: Paper in international publication
Authors: Tomasello, Alejandro, Ribo, Marc, Gramegna, Laura Ludovica, Melendez, Fernando, Rosati, Santiago, Moreu, Manuel, Aixut, Sonia, Luttich, Alexandre, Werner, Mariano, Remollo, Sebastian et al.
DOI: 10.1177/1591019919847623

Unraveling treatment response in multiple sclerosis: A clinical and MRI challenge.

PMID: 30587516
Journal: NEUROLOGY
Year: 2019
Reference: Neurology. 2019 Jan 22;92(4):180-192. doi: 10.1212/WNL.0000000000006810. Epub 2018 Dec 26.
Impact factor: 8.689
Publication type: Review in international publication
Authors: Gasperini, Claudio, Prosperini, Luca, Tintore, Mar, Sormani, Maria Pia, Filippi, Massimo, Rio, Jordi, Palace, Jacqueline, Rocca, Maria A, Ciccarelli, Olga, Barkhof, Frederik et al.
DOI: 10.1212/WNL.0000000000006810

[Tools to improve efficiency in the clinical management of hypertensive patients].

PMID: 30037730
Journal: Hipertension y riesgo vascular
Year: 2019
Reference: Hipertens Riesgo Vasc. 2019 Apr - Jun;36(2):70-84. doi: 10.1016/j.hipert.2018.06.002. Epub 2018 Jul 20.
Impact factor: 0
Publication type: Paper in national publication
Authors: Sabate, N, Merino, M, Ferrer-Vidal, D, Gorriz, J L, Muniz, O, Galgo, A, Hidalgo-Vega, A, Martell, N, Orozco-Beltran, D et al.
DOI: 10.1016/j.hipert.2018.06.002

Searching for the "Active Ingredients" in Physical Rehabilitation Programs Across Europe, Necessary to Improve Mobility in People With Multiple Sclerosis: A Multicenter Study.

PMID: 30880560
Journal: NEUROREHABILITATION AND NEURAL REPAIR
Year: 2019
Reference: Neurorehabil Neural Repair. 2019 Apr;33(4):260-270. doi: 10.1177/1545968319834893. Epub 2019 Mar 17.
Impact factor: 3.757
Publication type: Paper in international publication
Authors: Knuts, Kathy, Kalron, Alon, Feys, Peter, Dalgas, Ulrik, Smedal, Tori, Freeman, Jennifer, Romberg, Anders, Conyers, Helen, Elorriaga, Iratxe, Gebara, Benoit et al.
DOI: 10.1177/1545968319834893

Is the impact of fatigue related to walking capacity and perceived ability in persons with multiple sclerosis? A multicenter study.

PMID: 29571860
Journal: JOURNAL OF THE NEUROLOGICAL SCIENCES
Year: 2018
Reference: J Neurol Sci. 2018 Apr 15;387:179-186. doi: 10.1016/j.jns.2018.02.026. Epub 2018 Feb 16.
Impact factor: 2.448
Publication type: Paper in international publication
Authors: Jensen, E, Baert, I, Romberg, A, Santoyo Medina, C, Gebara, B, Maertens de Noordhout, B, Knuts, K, Bethoux, F, Rasova, K, Severijns, D et al.
DOI: 10.1016/j.jns.2018.02.026

Spinal cord lesions: A modest contributor to diagnosis in clinically isolated syndromes but a relevant prognostic factor.

PMID: 28301287
Journal: Multiple Sclerosis Journal
Year: 2018
Reference: Mult Scler. 2018 Mar;24(3):301-312. doi: 10.1177/1352458517697830. Epub 2017 Mar 16.
Impact factor: 5.28
Publication type: Paper in international publication
Authors: Arrambide, Georgina, Rovira, Alex, Sastre-Garriga, Jaume, Tur, Carmen, Castillo, Joaquin, Rio, Jordi, Vidal-Jordana, Angela, Galan, Ingrid, Rodriguez-Acevedo, Breogan, Midaglia, Luciana et al.
DOI: 10.1177/1352458517697830

Disability progression markers over 6-12 years in interferon-beta-treated multiple sclerosis patients.

PMID: 28287331
Journal: Multiple Sclerosis Journal
Year: 2018
Reference: Mult Scler. 2018 Mar;24(3):322-330. doi: 10.1177/1352458517698052. Epub 2017 Mar 13.
Impact factor: 5.28
Publication type: Paper in international publication
Authors: Castillo, Joaquin, Arrambide, Georgina, Nos, Carlos, Tur, Carmen, Pujal, Berta, Auger, Cristina, Sastre-Garriga, Jaume, Montalban, Xavier, Galan, Ingrid, Vidal-Jordana, Angela et al.
DOI: 10.1177/1352458517698052

Varicella-zoster meningovasculitis in a multiple sclerosis patient treated with natalizumab.

PMID: 28643544
Journal: Multiple Sclerosis Journal
Year: 2018
Reference: Mult Scler. 2018 Mar;24(3):358-360. doi: 10.1177/1352458517711569. Epub 2017 Jun 23.
Impact factor: 5.28
Publication type: Paper in international publication
Authors: Mulero, Patricia, Auger, Cristina, Parolin, Laura, Fonseca, Elena, Requena, Manuel, Rio, Jordi, Tintore, Mar, Rovira, Alex, Montalban, Xavier et al.
DOI: 10.1177/1352458517711569

Evaluating the effect of multiple sclerosis lesions on automatic brain structure segmentation.

PMID: 28540179
Journal: NeuroImage-Clinical
Year: 2017
Reference: Neuroimage Clin. 2017 May 8;15:228-238. doi: 10.1016/j.nicl.2017.05.003. eCollection 2017.
Impact factor: 4.348
Publication type: Paper in international publication
Authors: Pareto, Deborah, Vilanova, Joan C, Ramio-Torrenta, Lluis, Rovira, Alex, Oliver, Arnau, Llado, Xavier, Cabezas, Mariano, Valverde, Sergi, Gonzalez-Villa, Sandra et al.
DOI: 10.1016/j.nicl.2017.05.003

Improving automated multiple sclerosis lesion segmentation with a cascaded 3D convolutional neural network approach.

PMID: 28435096
Journal: NEUROIMAGE
Year: 2017
Reference: Neuroimage. 2017 Jul 15;155:159-168. doi: 10.1016/j.neuroimage.2017.04.034. Epub 2017 Apr 19.
Impact factor: 5.835
Publication type: Paper in international publication
Authors: Valverde, Sergi, Cabezas, Mariano, Roura, Eloy, Gonzalez-Villa, Sandra, Pareto, Deborah, Vilanova, Joan C, Ramio-Torrenta, Lluis, Rovira, Alex, Oliver, Arnau, Llado, Xavier et al.
DOI: 10.1016/j.neuroimage.2017.04.034

Brain Atrophy in Multiple Sclerosis: Clinical Relevance and Technical Aspects.

PMID: 28391787
Journal: NEUROIMAGING CLINICS OF NORTH AMERICA
Year: 2017
Reference: Neuroimaging Clin N Am. 2017 May;27(2):289-300. doi: 10.1016/j.nic.2017.01.002. Epub 2017 Feb 20.
Impact factor: 1.325
Publication type: Review in national publication
Authors: Sastre-Garriga, Jaume, Pareto, Deborah, Rovira, Alex et al.
DOI: 10.1016/j.nic.2017.01.002

MR Imaging in Monitoring and Predicting Treatment Response in Multiple Sclerosis.

PMID: 28391786
Journal: NEUROIMAGING CLINICS OF NORTH AMERICA
Year: 2017
Reference: Neuroimaging Clin N Am. 2017 May;27(2):277-287. doi: 10.1016/j.nic.2017.01.001. Epub 2017 Feb 14.
Impact factor: 1.325
Publication type: Review in national publication
Authors: Rio, Jordi, Auger, Cristina, Rovira, Alex et al.
DOI: 10.1016/j.nic.2017.01.001

Improved Automatic Detection of New T2 Lesions in Multiple Sclerosis Using Deformation Fields.

PMID: 27282863
Journal: AMERICAN JOURNAL OF NEURORADIOLOGY
Year: 2016
Reference: AJNR Am J Neuroradiol. 2016 Oct;37(10):1816-1823. doi: 10.3174/ajnr.A4829. Epub 2016 Jun 9.
Impact factor: 3.124
Publication type: Paper in international publication
Authors: Cabezas, M, Corral, J F, Oliver, A, Diez, Y, Tintore, M, Auger, C, Montalban, X, Llado, M, Pareto, D, Rovira, A et al.
DOI: 10.3174/ajnr.A4829

Short-term suboptimal response criteria for predicting long-term non-response to first-line disease modifying therapies in multiple sclerosis: A systematic review and meta-analysis.

PMID: 26810535
Journal: JOURNAL OF THE NEUROLOGICAL SCIENCES
Year: 2016
Reference: J Neurol Sci. 2016 Feb 15;361:158-67. doi: 10.1016/j.jns.2015.12.043. Epub 2015 Dec 29.
Impact factor: 2.126
Publication type: Review in national publication
Authors: Rio, Jordi, Ruiz-Pena, Juan Luis et al.
DOI: 10.1016/j.jns.2015.12.043

Brain Volume Loss during the First Year of Interferon-Beta Treatment: Baseline Inflammation and Tissue-Specific Volume Dynamics.

PMID: 26935253
Journal: JOURNAL OF NEUROIMAGING
Year: 2016
Reference: J Neuroimaging. 2016 Sep;26(5):532-8. doi: 10.1111/jon.12337. Epub 2016 Mar 2.
Impact factor: 1.625
Publication type: Paper in international publication
Authors: Rovira, Alex, Vidal-Jordana, Angela, Sastre-Garriga, Jaume, Perez-Miralles, Francisco, Pareto, Deborah, Rio, Jordi, Auger, Cristina, Tintore, Mar, Montalban, Xavier et al.
DOI: 10.1111/jon.12337

Lesion filling effect in regional brain volume estimations: a study in multiple sclerosis patients with low lesion load.

PMID: 26847633
Journal: NEURORADIOLOGY
Year: 2016
Reference: Neuroradiology. 2016 May;58(5):467-74. doi: 10.1007/s00234-016-1654-5. Epub 2016 Feb 4.
Impact factor: 2.274
Publication type: Paper in international publication
Authors: Aymerich, F X, Auger, C, Tintore, M, Montalban, X, Rovira, A, Sastre-Garriga, J, Pareto, D et al.
DOI: 10.1007/s00234-016-1654-5

A toolbox for multiple sclerosis lesion segmentation.

PMID: 26227167
Journal: NEURORADIOLOGY
Year: 2015
Reference: Neuroradiology. 2015 Oct;57(10):1031-43. doi: 10.1007/s00234-015-1552-2. Epub 2015 Jul 31.
Impact factor: 2.485
Publication type: Paper in international publication
Authors: Roura, Eloy, Oliver, Arnau, Cabezas, Mariano, Valverde, Sergi, Pareto, Deborah, Vilanova, Joan C, Ramio-Torrenta, Lluis, Rovira, Alex, Llado, Xavier et al.
DOI: 10.1007/s00234-015-1552-2

Any evident MRI T2 lesion activity should guide change of therapy in multiple sclerosis: no.

PMID: 25583834
Journal: Multiple Sclerosis Journal
Year: 2015
Reference: Mult Scler. 2015 Feb;21(2):132-3. doi: 10.1177/1352458514565415. Epub 2015 Jan 12.
Impact factor: 4.822
Publication type: Paper in international publication
Authors: Rio, Jordi et al.
DOI: 10.1177/1352458514565415

[Progressive multifocal leukoencephalopathy associated to natalizumab: the importance of magnetic resonance imaging in its early diagnosis].

PMID: 25670046
Journal: REVISTA DE NEUROLOGIA
Year: 2015
Reference: Rev Neurol. 2015 Feb 16;60(4):164-8.
Impact factor: 0.83
Publication type: Paper in national publication
Authors: Tintore, Mar, Sastre-Garriga, Jaume, Vidal, Anka, Castillo, Joaquin, Montalban, Xavier, Auger, Cristina, Rovira, Alex, Rio, Jordi, Marti, Gloria et al.
DOI:

Defining high, medium and low impact prognostic factors for developing multiple sclerosis.

PMID: 25902415
Journal: BRAIN
Year: 2015
Reference: Brain. 2015 Jul;138(Pt 7):1863-74. doi: 10.1093/brain/awv105. Epub 2015 Apr 21.
Impact factor: 9.196
Publication type: Paper in international publication
Authors: Tintore, Mar, Rovira, Alex, Rio, Jordi, Otero-Romero, Susana, Arrambide, Georgina, Tur, Carmen, Comabella, Manuel, Nos, Carlos, Arevalo, Maria Jesus, Negrotto, Laura et al.
DOI: 10.1093/brain/awv105

Treatment with interferon-beta does not induce anti-nuclear and anti-neuronal serum autoantibodies in multiple sclerosis patients.

PMID: 23182615
Journal: JOURNAL OF NEUROIMMUNOLOGY
Year: 2013
Reference: J Neuroimmunol. 2013 Feb 15;255(1-2):102-4. doi: 10.1016/j.jneuroim.2012.10.016. Epub 2012 Nov 22.
Impact factor: 3.033
Publication type: Paper in international publication
Authors: Comabella, M, Rentzsch, K, Rio, J, Bustamante, M F, Borowski, K, Stoecker, W, Montalban, X et al.
DOI: 10.1016/j.jneuroim.2012.10.016

[Therapy adherence to immunomodulator treatment in patients with multiple sclerosis].

PMID: 23250676
Journal: REVISTA DE NEUROLOGIA
Year: 2013
Reference: Rev Neurol. 2013 Jan 1;56(1):8-12.
Impact factor: 1.179
Publication type: Paper in national publication
Authors: Lopez-Mendez, P, Rio, J, Perez-Ricart, A, Tintore, M, Sastre-Garriga, J, Cardona-Pascual, I, Gomez-Domingo, M R, Montalban, X et al.
DOI:

Genome-wide scan of 500,000 single-nucleotide polymorphisms among responders and nonresponders to interferon beta therapy in multiple sclerosis.

PMID: 19667218
Journal: ARCHIVES OF NEUROLOGY
Year: 2009
Reference: Arch Neurol. 2009 Aug;66(8):972-8.
Impact factor: 5.874
Publication type: Paper in international publication
Authors: Comabella, Manuel, Craig, David W, Morcillo-Suarez, Carlos, Rio, Jordi, Navarro, Arcadi, Fernandez, Marta, Martin, Roland, Montalban, Xavier et al.
DOI: 10.1001/archneurol.2009.150

Predicting responders to therapies for multiple sclerosis.

PMID: 19794514
Journal: Nat Rev Neurol
Year: 2009
Reference: Nat Rev Neurol. 2009 Oct;5(10):553-60.
Impact factor:
Publication type: Letter or abstract
Authors: Rio, Jordi, Comabella, Manuel, Montalban, Xavier et al.
DOI: 10.1038/nrneurol.2009.139

A single-centre, randomized, double-blind, placebo-controlled study of interferon beta-1b on primary progressive and transitional multiple sclerosis.

PMID: 19797261
Journal: MULTIPLE SCLEROSIS
Year: 2009
Reference: Mult Scler. 2009 Oct;15(10):1195-205.
Impact factor: 3.312
Publication type: Paper in international publication
Authors: , , , , , , , , , et al.
DOI: 10.1177/1352458509106937

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In total, different projects of six research groups will be promoted, focusing on precision medicine and advanced therapies.

Dr. Carmen Espejo and Dr. Georgina Arrambide, researchers at Cemcat and Vall d'Hebron Research Institute, are the first authors of the article.

The research findings propose to modify the McDonald 2017 criteria, only in those in whom diagnosis using the current criteria is not possible.

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Simoa HD1 equipment

We are seeking healthy volunteers for a study to find biomarkers of multiple sclerosis

We are looking for 100 healthy volunteers aged 18 or over to participate in a project where the usefulness of biomarkers in serum will be evaluated to predict the prognosis of the disease and the response to treatments.

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