About the VHIR
Here at the Vall d'Hebron Research Institute (VHIR) we promote biomedical research, innovation and teaching. Over 1,800 people are seeking to understand diseases today so the treatment can be improved tomorrow.
Research
We are working to understand diseases, to find out how they operate and to create better treatments for patients. Get to know about our groups and their lines of research.
People
People are the centre of the Vall d'Hebron Research Institute (VHIR). This is why we are bound by the principles of freedom of research, gender equality and professional attitudes that HRS4R promotes.
Clinical trials
Our work is not just basic or translational; we are leaders in clinical research. Enter and find about the clinical trials we are conducting and why we are a world reference in this field.
Progress
Our aim is to make the research carried out at the Vall d’Hebron Research Institute (VHIR) a driving force for transformation. How? By identifying new channels and solutions for the promotion of people's health and well-being.
Core facilities
We offer specialist support for researchers, internal and external alike, ranging from specific services to preparing complete projects. All this, from a perspective of quality and speed of response.
News
We offer you a gateway for staying up to date on everything going on at the Vall d’Hebron Research Institute (VHIR), from the latest news to future solidarity activities and initiatives that we are organising.
The group of Clinical Neuroimmunology - Centre d'Esclerosi Múltiple de Catalunya (Cemcat) at the Vall d'Hebron Institut de Recerca (VHIR) is a multidisciplinary group dedicated to clinical assistance, physical and cognitive rehabilitation, and clinical and basic research on multiple sclerosis (MS). Cemcat is a national but also an international reference center in the clinical assistance of MS patients. The research performed in the group is divided and further combined in clinical and basic research. In addition, basic research has a marked translational character since the ultimate goal of the group is to improve the quality of life of patients suffering from MS, through in-depth knowledge of the pathogenic mechanisms of the disease and the development of new and more effective therapeutic approaches.
IP: Mar Tintore Subirana Collaborators: Genoveva Arqueros Sánchez, Xavier Montalban Gairín, Helena Ariño Rodríguez, Miriam Izquierdo Sans Funding agency: Instituto de Salud Carlos III Funding: 180000 Reference: JR22/00071 Duration: 20/02/2023 - 19/02/2026
IP: Carmen Espejo Ruiz Collaborators: Sara Marsal Barril, Herena Eixarch Ahufinger, Helena Borrell Paños, Maria America Lopez Lasanta Funding agency: Ministerio de Ciencia e Innovación-MICINN Funding: 217313.9 Reference: CPP2021-008475 Duration: 10/02/2022 - 09/02/2025
IP: Deborah Pareto Onghena Collaborators: Ingrid Galán Cartaña, Juan Fco. Corral Gamez, Herena Eixarch Ahufinger, M Jesus Arevalo Navines, Andrea De Barros Figueredo, Neus Mongay Ochoa, Giorgio Colangelo Funding agency: Instituto de Salud Carlos III Funding: 87120 Reference: PI22/01709 Duration: 01/01/2023 - 31/12/2025
IP: Jaume Sastre Garriga Collaborators: Cristina Auger Acosta, Carme Santoyo Medina, Manel Alberich Jordà, M Jesus Arevalo Navines, Xavier Montalban Gairín, Lucía Gutiérrez Ruiz, Neus Mongay Ochoa Funding agency: Instituto de Salud Carlos III Funding: 157300 Reference: PI22/00750 Duration: 01/01/2023 - 31/12/2025
PMID: 37535170 Journal: CELLULAR AND MOLECULAR LIFE SCIENCES Year: 2023 Reference: Cell Mol Life Sci. 2023 Aug 3;80(8):238. doi: 10.1007/s00018-023-04882-w. Impact factor: Publication type: Paper in international publication Authors: Alberch, Jordi; Allen, Nicholas D; Bombau, Georgina; Borras, Francesc E; Canals, Josep M; Fernandez-Garcia, Sara; Fernandez-Medina, Helena; Galofre, Mireia; Garcia-Bravo, Maria; Gomis, Cinta et al. DOI: 10.1007/s00018-023-04882-w
PMID: 37559720 Journal: Frontiers in Immunology Year: 2023 Reference: Front Immunol. 2023 Jul 25;14:1233546. doi: 10.3389/fimmu.2023.1233546. eCollection 2023. Impact factor: Publication type: Paper in international publication Authors: Borras, Eva; Boschert, Ursula; Calvo-Barreiro, Laura; Comabella, Manuel; Costa-Frossard, Lucienne; Eixarch, Herena; Espejo, Carmen; Ferrer, Mireia; Fissolo, Nicolas; Montalban, Xavier et al. DOI: 10.3389/fimmu.2023.1233546
PMID: 37593971 Journal: TRANSFUSION Year: 2023 Reference: Transfusion. 2023 Aug 18. doi: 10.1111/trf.17498. Impact factor: Publication type: Letter or abstract Authors: Alvarez Arguelles, Marta Elena; Garcia-Gala, Jose Maria; Mata, Pablo; Munoz, Maria Del Carmen; Ojea, Ana Maria; Quer Sivila, Josep; Rando Segura, Ariadna; Rodriguez, Mercedes; Rodriguez-Frias, Francisco; Seco, Carolina et al. DOI: 10.1111/trf.17498
PMID: 37589724 Journal: ACTA NEUROCHIRURGICA Year: 2023 Reference: Acta Neurochir (Wien). 2023 Aug 17. doi: 10.1007/s00701-023-05739-8. Impact factor: Publication type: Paper in international publication Authors: Arikan, Fuat; Coscojuela, Pilar; De Barros, Andrea; Dinia, Lavinia; Gandara, Dario; Gramegna, Laura Ludovica; Hernandez, David; Luzi, Michele; Martinez-Saez, Elena; Quintana, Manuel et al. DOI: 10.1007/s00701-023-05739-8
PMID: 35765217 Journal: Multiple Sclerosis Journal Year: 2022 Reference: Mult Scler. 2022 Jun 28:13524585221102584. doi: 10.1177/13524585221102584. Impact factor: 6.312 Publication type: Paper in international publication Authors: Sheffield, James K; Minton, Neil; Cheng, Chun-Yen; Silva, Diego; Kappos, Ludwig; Cohen, Jeffrey A; Havrdova, Eva K; Montalban, Xavier; Hartung, Hans-Peter; Cree, Bruce Ac et al. DOI: 10.1177/13524585221102584
PMID: 35778721 Journal: Systematic Reviews Year: 2022 Reference: Syst Rev. 2022 Jul 1;11(1):134. doi: 10.1186/s13643-022-01997-2. Impact factor: 2.522 Publication type: Paper in international publication Authors: Rahn, Anne C; Heesen, Christoph; Fittipaldo, Andrea V; Chard, Declan; Rio, Jordi; Kopke, Sascha; Rover, Christian; Lehnert, Thomas; Friede, Tim et al. DOI: 10.1186/s13643-022-01997-2
PMID: 35799407 Journal: JOURNAL OF CLINICAL NURSING Year: 2022 Reference: J Clin Nurs. 2022 Jul 7. doi: 10.1111/jocn.16421. Impact factor: 3.036 Publication type: Paper in international publication Authors: Artola, Montse; Sola-Valls, Nuria; Saiz, Albert; Montero, Laura; Fornali, Olga; Mercade, Laura; Matamoros, Mandi; Molinos, Consuelo; Leon, Isabel; Zabay, Cinta et al. DOI: 10.1111/jocn.16421
PMID: 34720200 Journal: PATTERN RECOGNITION Year: 2022 Reference: Pattern Recognit. 2022 Mar;123:108403. doi: 10.1016/j.patcog.2021.108403. Epub 2021 Oct 26. Impact factor: 7.74 Publication type: Paper in international publication Authors: Liu, Shuo; Han, Jing; Puyal, Estela Laporta; Kontaxis, Spyridon; Sun, Shaoxiong; Locatelli, Patrick; Dineley, Judith; Pokorny, Florian B; Costa, Gloria Dalla; Leocani, Letizia et al. DOI: 10.1016/j.patcog.2021.108403
PMID: 34237417 Journal: AUTOIMMUNITY REVIEWS Year: 2021 Reference: Autoimmun Rev. 2021 Sep;20(9):102893. doi: 10.1016/j.autrev.2021.102893. Epub 2021 Jul 5. Impact factor: 9.754 Publication type: Review in international publication Authors: Dema, Maria, Eixarch, Herena, Villar, Luisa M, Montalban, Xavier, Espejo, Carmen et al. DOI: 10.1016/j.autrev.2021.102893
PMID: 33237430 Journal: NEURORADIOLOGY Year: 2021 Reference: Neuroradiology. 2021 Jul;63(7):1031-1041. doi: 10.1007/s00234-020-02604-8. Epub 2020 Nov 25. Impact factor: 2.804 Publication type: Paper in international publication Authors: Perez-Miralles, Francisco Carlos, Rio, Jordi, Pareto, Deborah, Vidal-Jordana, Angela, Auger, Cristina, Arrambide, Georgina, Castillo, Joaquin, Tintore, Mar, Rovira, Alex, Montalban, Xavier et al. DOI: 10.1007/s00234-020-02604-8
PMID: 34052900 Journal: MAGNETIC RESONANCE MATERIALS IN PHYSICS BIOLOGY AND MEDICINE Year: 2021 Reference: MAGMA. 2021 Dec;34(6):903-914. doi: 10.1007/s10334-021-00933-0. Epub 2021 May 29. Impact factor: 2.31 Publication type: Paper in international publication Authors: Alonso, Juli, Pareto, Deborah, Alberich, Manel, Kober, Tobias, Marechal, Benedicte, Llado, Xavier, Rovira, Alex et al. DOI: 10.1007/s10334-021-00933-0
PMID: 33786942 Journal: EUROPEAN JOURNAL OF NEUROLOGY Year: 2021 Reference: Eur J Neurol. 2021 Aug;28(8):2533-2542. doi: 10.1111/ene.14845. Epub 2021 Apr 19. Impact factor: 6.089 Publication type: Paper in international publication Authors: Rovira, Alex, Tintore, Mar, Sastre-Garriga, Jaume, Tortorella, Carla, Haggiag, Shalom, Galgani, Simonetta, Capra, Ruggero, Pozzilli, Carlo, Montalban, Xavier, Rio, Jordi et al. DOI: 10.1111/ene.14845
PMID: 32681355 Journal: Neurotherapeutics Year: 2020 Reference: Neurotherapeutics. 2020 Oct;17(4):1988-2003. doi: 10.1007/s13311-020-00885-8. Impact factor: 6.035 Publication type: Paper in international publication Authors: Castillo, Mireia, Eixarch, Herena, Calvo-Barreiro, Laura, Costa, Carme, Reverter-Vives, Gemma, Montalban, Xavier, Espejo, Carmen, Del Rio, Jose Antonio, Gil, Vanessa et al. DOI: 10.1007/s13311-020-00885-8
PMID: 32676962 Journal: CARDIOVASCULAR AND INTERVENTIONAL RADIOLOGY Year: 2020 Reference: Cardiovasc Intervent Radiol. 2020 Nov;43(11):1679-1686. doi: 10.1007/s00270-020-02594-3. Epub 2020 Jul 16. Impact factor: 2.034 Publication type: Paper in international publication Authors: Pinana, Carlos, Gramegna, Laura Ludovica, Folleco, Edgar, Requena, Manuel, Hernandez, David, Tomasello Weitz, Alejandro et al. DOI: 10.1007/s00270-020-02594-3
PMID: 32630765 Journal: International Journal of Environmental Research and Public Health Year: 2020 Reference: Int J Environ Res Public Health. 2020 Jul 2;17(13). pii: ijerph17134774. doi: 10.3390/ijerph17134774. Impact factor: 2.849 Publication type: Paper in international publication Authors: Rasova, Kamila, Martinkova, Patricia, Soler, Bernadita, Freeman, Jenny, Cattaneo, Davide, Jonsdottir, Johanna, Smedal, Tori, Romberg, Anders, Henze, Thomas, Santoyo-Medina, Carme et al. DOI: 10.3390/ijerph17134774
PMID: 32617741 Journal: NEUROLOGICAL SCIENCES Year: 2020 Reference: Neurol Sci. 2020 Jul 2. pii: 10.1007/s10072-020-04519-x. doi: 10.1007/s10072-020-04519-x. Impact factor: 2.415 Publication type: Paper in international publication Authors: Dobson, Richard J B, Dalla Costa, Gloria, Leocani, Letizia, Montalban, Xavier, Guerrero, Ana Isabel, Sorensen, Per Soelberg, Magyari, Melinda, Hotopf, Matthew, Comi, Giancarlo, Narayan, Vaibhav A et al. DOI: 10.1007/s10072-020-04519-x
PMID: 30587519 Journal: NEUROLOGY Year: 2019 Reference: Neurology. 2019 Feb 5;92(6):296-298. doi: 10.1212/WNL.0000000000006801. Epub 2018 Dec 26. Impact factor: 8.689 Publication type: Paper in international publication Authors: Pappolla, Agustin, Midaglia, Luciana, Boix Rodriguez, Claudia P, Puig, Adaia Albasanz, Lung, Maiylyi, Camps, Isabel Ruiz, Castillo, Joaquin, Mulero, Patricia, Arrambide, Georgina, Rodriguez-Acevedo, Breogan et al. DOI: 10.1212/WNL.0000000000006801
PMID: 30687923 Journal: REVISTA DE NEUROLOGIA Year: 2019 Reference: Rev Neurol. 2019 Feb 1;68(3):132-133. Impact factor: 0.485 Publication type: Letter whit IF Authors: Llaurado-Gayete, A, Campos-Fernandez, D, Olive-Gadea, M, Ballve-Martin, A, Rio, J, Rovira, A, Santamarina, E et al. DOI: 10.33588/rn.6803.2018377
PMID: 30623863 Journal: Multiple Sclerosis and Related Disorders Year: 2019 Reference: Mult Scler Relat Disord. 2019 Feb;28:230-234. doi: 10.1016/j.msard.2019.01.007. Epub 2019 Jan 3. Impact factor: 2.725 Publication type: Paper in international publication Authors: Sepulveda, Maria, Armangue, Thais, Sabater, Lidia, Martinez-Hernandez, Eugenia, Arrambide, Georgina, Blanco, Yolanda, Llufriu, Sara, Martinez-Lapiscina, Elena H, Mulero, Patricia, Sola-Valls, Nuria et al. DOI: 10.1016/j.msard.2019.01.007
PMID: 30035845 Journal: EUROPEAN JOURNAL OF NEUROLOGY Year: 2019 Reference: Eur J Neurol. 2019 Jan;26(1):41-50. doi: 10.1111/ene.13760. Epub 2018 Sep 9. Impact factor: 4.387 Publication type: Paper in international publication Authors: Kopke, Sascha, Giordano, Andrea, Veronese, Simone, Rahn, Anne Christin, Kleiter, Ingo, Basedow-Rajwich, Birgit, Fornari, Arianna, Battaglia, Mario Alberto, Drulovic, Jelena, Kooij, Liesbeth et al. DOI: 10.1111/ene.13760
PMID: 29027004 Journal: JOURNAL OF NEUROLOGY Year: 2018 Reference: J Neurol. 2018 Jan;265(1):24-31. doi: 10.1007/s00415-017-8625-6. Epub 2017 Oct 12. Impact factor: 3.783 Publication type: Paper in international publication Authors: Villar, Luisa M, Alvarez-Cermeno, Jose C, Montalban, Xavier, Dominguez-Mozo, Maria I, Alenda, Raquel, Costa-Frossard, Lucienne, Alvarez-Lafuente, Roberto, Espejo, Carmen, Rodriguez-Martin, Eulalia, de la Maza, Susana Sainz et al. DOI: 10.1007/s00415-017-8625-6
PMID: 29251340 Journal: REVISTA DE NEUROLOGIA Year: 2018 Reference: Rev Neurol. 2018 Jan 1;66(1):25-32. Impact factor: 0.601 Publication type: Review in national publication Authors: Midaglia, L, Mora, L, Mulero, P, Sastre-Garriga, J, Montalban, X et al. DOI: 10.33588/rn.6601.2017213
PMID: 29234597 Journal: NeuroImage-Clinical Year: 2018 Reference: Neuroimage Clin. 2017 Nov 20;17:607-615. doi: 10.1016/j.nicl.2017.11.015. eCollection 2018. Impact factor: 3.869 Publication type: Paper in international publication Authors: Salem, Mostafa, Cabezas, Mariano, Pareto, Deborah, Oliver, Arnau, Salvi, Joaquim, Rovira, Alex, Llado, Xavier, Valverde, Sergi et al. DOI: 10.1016/j.nicl.2017.11.015
PMID: 25586466 Journal: BRAIN Year: 2015 Reference: Brain. 2015 Mar;138(Pt 3):644-52. doi: 10.1093/brain/awu388. Epub 2015 Jan 12. Impact factor: 9.196 Publication type: Paper in international publication Authors: Chan, Andrew, Martinelli-Boneschi, Filippo, Garcia-Merino, Antonio, Montalban, Xavier, Comabella, Manuel, Drulovic, Jelena, Lechner-Scott, Jeannette, Brassat, David, Malhotra, Sunny, Rio, Jordi et al. DOI: 10.1093/brain/awu388
In total, different projects of six research groups will be promoted, focusing on precision medicine and advanced therapies.
Dr. Carmen Espejo and Dr. Georgina Arrambide, researchers at Cemcat and Vall d'Hebron Research Institute, are the first authors of the article.
The research findings propose to modify the McDonald 2017 criteria, only in those in whom diagnosis using the current criteria is not possible.
Simoa HD1 equipment
We are looking for 100 healthy volunteers aged 18 or over to participate in a project where the usefulness of biomarkers in serum will be evaluated to predict the prognosis of the disease and the response to treatments.
