About the VHIR
Here at the Vall d'Hebron Research Institute (VHIR) we promote biomedical research, innovation and teaching. Over 1,800 people are seeking to understand diseases today so the treatment can be improved tomorrow.
Research
We are working to understand diseases, to find out how they operate and to create better treatments for patients. Get to know about our groups and their lines of research.
People
People are the centre of the Vall d'Hebron Research Institute (VHIR). This is why we are bound by the principles of freedom of research, gender equality and professional attitudes that HRS4R promotes.
Clinical trials
Our work is not just basic or translational; we are leaders in clinical research. Enter and find about the clinical trials we are conducting and why we are a world reference in this field.
Progress
Our aim is to make the research carried out at the Vall d’Hebron Research Institute (VHIR) a driving force for transformation. How? By identifying new channels and solutions for the promotion of people's health and well-being.
Core facilities
We offer specialist support for researchers, internal and external alike, ranging from specific services to preparing complete projects. All this, from a perspective of quality and speed of response.
News
We offer you a gateway for staying up to date on everything going on at the Vall d’Hebron Research Institute (VHIR), from the latest news to future solidarity activities and initiatives that we are organising.
The group of Clinical Neuroimmunology - Centre d'Esclerosi Múltiple de Catalunya (Cemcat) at the Vall d'Hebron Institut de Recerca (VHIR) is a multidisciplinary group dedicated to clinical assistance, physical and cognitive rehabilitation, and clinical and basic research on multiple sclerosis (MS). Cemcat is a national but also an international reference center in the clinical assistance of MS patients. The research performed in the group is divided and further combined in clinical and basic research. In addition, basic research has a marked translational character since the ultimate goal of the group is to improve the quality of life of patients suffering from MS, through in-depth knowledge of the pathogenic mechanisms of the disease and the development of new and more effective therapeutic approaches.
IP: Macarena Simon-Talero Horga Collaborators: Joaquin Castillo Justribo, Mònica Pons Delgado Funding agency: Instituto de Salud Carlos III Funding: 60500 Reference: PI21/00312 Duration: 01/01/2022 - 31/12/2024
IP: Manuel Comabella Lopez Collaborators: Human induced pluripotent stem cell-based chimeric mice to study astrocyte pathology and neuroprotective strategies in multiple , Rucsanda Pinteac, Sira Rodrigo Bosch Funding agency: Instituto de Salud Carlos III Funding: 286770 Reference: PI21/01611 Duration: 01/01/2022 - 31/12/2024
IP: Manuel Comabella Lopez Collaborators: - Funding agency: National Multiple Sclerosis Society Funding: 300486.36 Reference: RIS_NMSS-PMSC2021 Duration: 01/05/2022 - 31/10/2024
PMID: 37782540 Journal: JMIR formative research Year: 2023 Reference: JMIR Form Res. 2023 Oct 2;7:e46521. doi: 10.2196/46521. Impact factor: Publication type: Paper in international publication Authors: Bernasconi, Corrado; Dondelinger, Frank; Elantkowski, Marcin; Graves, Jennifer S; Lindemann, Michael; Lipsmeier, Florian; Midaglia, Luciana; Montalban, Xavier; Zhang, Yan-Ping et al. DOI: 10.2196/46521
PMID: 37803817 Journal: JOURNAL OF MAGNETIC RESONANCE IMAGING Year: 2023 Reference: J Magn Reson Imaging. 2023 Oct 6. doi: 10.1002/jmri.29046. Impact factor: Publication type: Paper in international publication Authors: Alberich, Manel; Alberich, Manel; Arrambide, Georgina; Auger, Cristina; Auger, Cristina; Carbonell-Mirabent, Pere; Castillo, Joaqui N; Cobo-Calvo, Alvaro; Cobo-Calvo, Alvaro; Coll, Llucia et al. DOI: 10.1002/jmri.29046
PMID: 37813596 Journal: Neurology-Neuroimmunology & Neuroinflammation Year: 2023 Reference: Neurol Neuroimmunol Neuroinflamm. 2023 Oct 9;10(6):e200169. doi: 10.1212/NXI.0000000000200169. Print 2023 Nov. Impact factor: Publication type: Paper in international publication Authors: Al-Louzi, Omar; Albrecht, Philipp; Aly, Lilian; Banze, Nicolas; Baumann, Carmen; Cabello, Sergio; Calabresi, Peter A; Ciccarelli, Olga; Feucht, Nikolaus; Garcia-Martin, Elena et al. DOI: 10.1212/NXI.0000000000200169
PMID: 37183562 Journal: EUROPEAN JOURNAL OF NEUROLOGY Year: 2023 Reference: Eur J Neurol. 2023 May 14. doi: 10.1111/ene.15866. Impact factor: Publication type: Paper in international publication Authors: Chuquisana, Omar; Comabella, Manuel; Ferrer, Roser; Fissolo, Nicolas; Gil-Varea, Elia; Giralt, Marina; Lunemann, Jan D; Malhotra, Sunny; Midaglia, Luciana; Montalban, Xavier et al. DOI: 10.1111/ene.15866
PMID: 35475363 Journal: Multiple Sclerosis Journal Year: 2022 Reference: Mult Scler. 2022 Jun;28(7):1138-1145. doi: 10.1177/13524585221089540. Epub 2022 Apr 27. Impact factor: 6.312 Publication type: Paper in international publication Authors: Arrambide, Georgina, Otero-Romero, Susana, Pappolla, Agustin, Tagliani, Paula, Lopez-Maza, Samuel, Cardenas-Robledo, Simon, Esperalba, Juliana, Fernandez-Naval, Candela, Martinez-Gallo, Monica, Castillo, Mireia et al. DOI: 10.1177/13524585221089540
PMID: 34841948 Journal: Multiple Sclerosis Journal Year: 2022 Reference: Mult Scler. 2022 May;28(6):950-957. doi: 10.1177/13524585211053001. Epub 2021 Nov 29. Impact factor: 6.312 Publication type: Paper in international publication Authors: Rodriguez, Marta, Otero-Romero, Susana, Carbonell-Mirabent, Pere, Midaglia, Luciana, Zuluaga, Maria, Galan, Ingrid, Cobo-Calvo, Alvaro, Rio, Jordi, Arrambide, Georgina, Vidal-Jordana, Angela et al. DOI: 10.1177/13524585211053001
PMID: 35428030 Journal: Multiple Sclerosis and Related Disorders Year: 2022 Reference: Mult Scler Relat Disord. 2022 Jun;62:103799. doi: 10.1016/j.msard.2022.103799. Epub 2022 Apr 10. Impact factor: 4.339 Publication type: Paper in international publication Authors: Rasova, Kamila, Jonsdottir, Johanna, Medina, Carme Santoyo, Kos, Daphne, Coote, Susan, Tacchino, Andrea, Smedal, Tori, Arntzen, Ellen Christin, Quinn, Gillian, Learmonth, Yvonne et al. DOI: 10.1016/j.msard.2022.103799
PMID: 35364228 Journal: NEUROSCIENCE Year: 2022 Reference: Neuroscience. 2022 Jul 15;495:86-96. doi: 10.1016/j.neuroscience.2022.03.031. Epub 2022 Mar 29. Impact factor: 3.59 Publication type: Paper in international publication Authors: Frieske, Joana, Cuypers, Koen, Meesen, Raf L J, Alonso, Juli, Arevalo, Maria Jesus, Galan, Ingrid, Renom, Marta, Vidal-Jordana, Angela, Auger, Cristina, Montalban, Xavier et al. DOI: 10.1016/j.neuroscience.2022.03.031
PMID: 32390131 Journal: REVISTA DE NEUROLOGIA Year: 2020 Reference: Rev Neurol. 2020 May 16;70(10):379-390. doi: 10.33588/rn.7010.2020121. Impact factor: 0.562 Publication type: Review in national publication Authors: Prieto, J M, Fernandez, O, Aladro, Y, Arroyo, R, Brieva, Ll, Calles-Hernandez, M C, Carrascal, P, Comabella, M, Costa-Frossard, L, Eichau, S et al. DOI: 10.33588/rn.7010.2020121
PMID: 30887862 Journal: Multiple Sclerosis Journal Year: 2020 Reference: Mult Scler. 2020 Apr;26(4):476-488. doi: 10.1177/1352458519837707. Epub 2019 Mar 19. Impact factor: 5.412 Publication type: Paper in international publication Authors: Koini, Marisa, d'Ambrosio, Alessandro, Valsasina, Paola, Gallo, Antonio, De Stefano, Nicola, Pareto, Deborah, Barkhof, Frederik, Ciccarelli, Olga, Enzinger, Christian, Tedeschi, Gioacchino et al. DOI: 10.1177/1352458519837707
PMID: 32246177 Journal: NEURORADIOLOGY Year: 2020 Reference: Neuroradiology. 2020 Aug;62(8):955-964. doi: 10.1007/s00234-020-02401-3. Epub 2020 Apr 3. Impact factor: 2.238 Publication type: Paper in international publication Authors: Cappelle, Sarah, Pareto, Deborah, Tintore, Mar, Alyafeai, Rumaiza, Vidal-Jordana, Angela, Alberich, Manel, Sastre-Garriga, Jaume, Auger, Cristina, Montalban, Xavier, Rovira, Alex et al. DOI: 10.1007/s00234-020-02401-3
PMID: 32176761 Journal: Journal of Gastrointestinal and Liver Diseases Year: 2020 Reference: J Gastrointestin Liver Dis. 2020 Mar 13;29(1):65-68. doi: 10.15403/jgld-806. Impact factor: 2.351 Publication type: Paper in international publication Authors: Pribic, Teodora, Lopez, Quiro, Lucas, Eduardo, Livovsky, Dan M, Rovira, Alex, Accarino, Anna, Azpiroz, Fernando, Pareto, Deborah et al. DOI: 10.15403/jgld-806
In total, different projects of six research groups will be promoted, focusing on precision medicine and advanced therapies.
Dr. Carmen Espejo and Dr. Georgina Arrambide, researchers at Cemcat and Vall d'Hebron Research Institute, are the first authors of the article.
The research findings propose to modify the McDonald 2017 criteria, only in those in whom diagnosis using the current criteria is not possible.
Simoa HD1 equipment
We are looking for 100 healthy volunteers aged 18 or over to participate in a project where the usefulness of biomarkers in serum will be evaluated to predict the prognosis of the disease and the response to treatments.
