About the VHIR
Here at the Vall d'Hebron Research Institute (VHIR) we promote biomedical research, innovation and teaching. Over 1,800 people are seeking to understand diseases today so the treatment can be improved tomorrow.
Research
We are working to understand diseases, to find out how they operate and to create better treatments for patients. Get to know about our groups and their lines of research.
People
People are the centre of the Vall d'Hebron Research Institute (VHIR). This is why we are bound by the principles of freedom of research, gender equality and professional attitudes that HRS4R promotes.
Clinical trials
Our work is not just basic or translational; we are leaders in clinical research. Enter and find about the clinical trials we are conducting and why we are a world reference in this field.
Progress
Our aim is to make the research carried out at the Vall d’Hebron Research Institute (VHIR) a driving force for transformation. How? By identifying new channels and solutions for the promotion of people's health and well-being.
Core facilities
We offer specialist support for researchers, internal and external alike, ranging from specific services to preparing complete projects. All this, from a perspective of quality and speed of response.
News
We offer you a gateway for staying up to date on everything going on at the Vall d’Hebron Research Institute (VHIR), from the latest news to future solidarity activities and initiatives that we are organising.
The Diabetes and Metabolism Research Group is search is lead by Dr. Rafael Simó (Hirsch index:54), Head of the Endocrinology Department, Professor of Medicine & Endocrinology at UAB and current President of the European Association for the Study of Diabetes-Eye Complications. The group consists of 7 senior clinical investigators, 4 basic post-doctoral researchers, 4 pre-doc researchers, 3 laboratory technicians and one coordinator of clinical assays.
The group belongs to “CIBER” of Diabetes and Associated Metabolic Diseases (CIBERDEM. ISCIII) and has been recognized as consolidated group by the Generalitat de Catalunya (AQU/AGAUR).
Since 2014 this group has been qualified as outstanding in the evaluations performed by the ANEP, CIBERDEM and the external Scientific Advisory Board of VHIR.
The main lines of research are:
IP: Josep A Villena Delgado Collaborators: Rosario Pardo Diaz, Andreea Ciudin Mihai, Marta Comas Martínez, Ramón Vilallonga Puy, Enzamaría Fidilio Meli Funding agency: Instituto de Salud Carlos III Funding: 248050 Reference: AC22/00023 Duration: 01/01/2023 - 31/12/2025
IP: Rafael Simó Canonge Collaborators: Josep A Villena Delgado, Carles Zafon Llopis, Cristina Hernández Pascual, David Martinez Selva, Rosario Pardo Diaz, Angel Michael Ortiz Zuñiga, Andreea Ciudin Mihai, Fiorella Ximena Palmas Candia, Ana Maria Ortiz de Urbina Olive, Monica Sanchez Bartres, Lorena Ramos Pérez, Marc Rivas Agudo, Anna Deàs Just, Anna Casteras Román, Alejandra Planas Vilaseca, Betina Biagetti Biagetti, Judit Amigó Farran, Mercè Abad Martín, Marta Comas Martínez, Hugo Ramos Abellan, Rosa Burgos Peláez, David Sabater Martínez, Olga Simó Servat, Patricia Bogdanov Baruj, Maria Llorian Salvador, Enzamaría Fidilio Meli Funding agency: Agència Gestió Ajuts Universitaris i de Recerca Funding: 60000 Reference: 2021 SGR 00655 Duration: 01/01/2022 - 30/06/2025
IP: Rafael Simó Canonge Collaborators: Anna Duarri Piqué, Cristina Hernández Pascual, Hugo Ramos Abellan, Patricia Bogdanov Baruj Funding agency: Ministerio de Ciencia e Innovación-MICINN Funding: 128570 Reference: PDC2022-133991-I00 Duration: 01/12/2022 - 30/11/2024
IP: Josep A Villena Delgado Collaborators: Angel Michael Ortiz Zuñiga, Laura Hidalgo Corbacho, Alba Rojano Toimil, Ramón Vilallonga Puy Funding agency: Ministerio de Ciencia e Innovación-MICINN Funding: 217800 Reference: PID2021-123377OB-I00 Duration: 01/09/2022 - 31/08/2025
PMID: 37762304 Journal: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES Year: 2023 Reference: Int J Mol Sci. 2023 Sep 12;24(18):14002. doi: 10.3390/ijms241814002. Impact factor: Publication type: Review in international publication Authors: Araujo-Castro, Marta; Biagetti, Betina; Biagetti, Betina; Marazuela, Monica; Puig-Domingo, Manel et al. DOI: 10.3390/ijms241814002
PMID: 37799531 Journal: Frontiers in Psychology Year: 2023 Reference: Front Psychol. 2023 Sep 18;14:1209245. doi: 10.3389/fpsyg.2023.1209245. eCollection 2023. Impact factor: Publication type: Paper in international publication Authors: Canizares, Silvia; Ciudin, Andreea; Ciudin, Andreea; Comas, Marta; Comas, Marta; Cuatrecasas, Guillem; Diaz-Trastoy, Olaia; Flores, Lilliam; Goni, Fernando; Gutierrez-Medina, Sonsoles et al. DOI: 10.3389/fpsyg.2023.1209245
PMID: 37813743 Journal: Nefrologia Year: 2023 Reference: Nefrologia (Engl Ed). 2023 Oct 7:S2013-2514(23)00146-3. doi: 10.1016/j.nefroe.2023.09.002. Impact factor: Publication type: Review in international publication Authors: Facila, Lorenzo; Gonzalez-Juanatey, Jose Ramon; Gorriz, Jose Luis; Ortiz, Alberto; Soler, Maria Jose; Valle, Alfonso et al. DOI: 10.1016/j.nefroe.2023.09.002
PMID: 37835008 Journal: Journal of Clinical Medicine Year: 2023 Reference: J Clin Med. 2023 Oct 4;12(19):6364. doi: 10.3390/jcm12196364. Impact factor: Publication type: Paper in international publication Authors: Amigo, Judit; Franch-Nadal, Josep; Hernandez, Cristina; Martins, Sheila Cristina Ouriques; Mayor, Regina; Molina, Carlos; Morer, Carla; Nogueira, Raul; Ortiz-Zuniga, Angel; Sanchez, Monica et al. DOI: 10.3390/jcm12196364
PMID: 35363561 Journal: Journal of Laparoendoscopic & Advanced Surgical Te Year: 2022 Reference: J Laparoendosc Adv Surg Tech A. 2022 Apr 1. doi: 10.1089/lap.2021.0863. Impact factor: 1.878 Publication type: Paper in international publication Authors: Ortiz-Zuniga, Angel Michael, Costa Forner, Pilar, Cirera de Tudela, Arturo, Garcia Ruiz, Amador, Comas Martinez, Marta, Palmas, Fiorella, Morer Linan, Carla, Vilallonga, Ramon, Ciudin, Andreea et al. DOI: 10.1089/lap.2021.0863
PMID: 35351135 Journal: BMC Medicine Year: 2022 Reference: BMC Med. 2022 Mar 29;20(1):129. doi: 10.1186/s12916-022-02345-w. Impact factor: 8.775 Publication type: Paper in international publication Authors: Gallo, Monica Martinez, Arrese-Munoz, Iria, Gine, Anna, Diaz-Troyano, Noelia, Gabriel-Medina, Pablo, Riveiro-Barciela, Mar, Labrador-Horrillo, Moises, Martinez-Valle, Fernando, Montalva, Adrian Sanchez, Hernandez-Gonzalez, Manuel et al. DOI: 10.1186/s12916-022-02345-w
PMID: 35256061 Journal: Endocrinologia Diabetes y Nutricion Year: 2022 Reference: Endocrinol Diabetes Nutr (Engl Ed). 2022 Feb;69(2):155-156. doi: 10.1016/j.endien.2022.02.004. Impact factor: 1.417 Publication type: Letter or abstract Authors: Cordero-Vazquez, Efrain, Filippi-Arriaga, Francesca, Hernandez, Irene Hernandez, Haman, Stephanie Solange Tasayco, Ciudin, Andreea et al. DOI: 10.1016/j.endien.2022.02.004
PMID: 35232561 Journal: Endocrinologia Diabetes y Nutricion Year: 2022 Reference: Endocrinol Diabetes Nutr (Engl Ed). 2022 Jan;69(1):63-69. doi: 10.1016/j.endien.2022.01.001. Epub 2022 Feb 16. Impact factor: 1.417 Publication type: Paper in international publication Authors: Biagetti, Betina, Ferrer Costa, Roser, Alfayate Guerra, Rocio, Alvarez Garcia, Elias, Berlanga Escalera, Eugenio, Casals, Gregori, Esteban Salan, Margarita, Granada Ibern, Maria-Luisa, Gorrin Ramos, Jorge, Lopez Lazareno, Nieves et al. DOI: 10.1016/j.endien.2022.01.001
PMID: 34238673 Journal: Hipertension y riesgo vascular Year: 2021 Reference: Hipertens Riesgo Vasc. 2021 Oct-Dec;38(4):201-205. doi: 10.1016/j.hipert.2021.05.003. Epub 2021 Jul 6. Impact factor: 0 Publication type: Letter or abstract Authors: Bury, R, Leon Roman, J, Casteras, A, Vergara, A, Biagetti, B, Garcia-Carro, C, Cordero-Vazquez, E, Hernandez Hernandez, I, Agraz, I, Soler, M J et al. DOI: 10.1016/j.hipert.2021.05.003
PMID: 34242330 Journal: PLoS One Year: 2021 Reference: PLoS One. 2021 Jul 9;16(7):e0254243. doi: 10.1371/journal.pone.0254243. eCollection 2021. Impact factor: 3.24 Publication type: Paper in international publication Authors: Llorens-Revull, Meritxell, Costafreda, Maria Isabel, Rico, Angie, Guerrero-Murillo, Mercedes, Soria, Maria Eugenia, Piriz-Ruzo, Sofia, Vargas-Accarino, Elena, Gabriel-Medina, Pablo, Rodriguez-Frias, Francisco, Riveiro-Barciela, Mar et al. DOI: 10.1371/journal.pone.0254243
PMID: 34104210 Journal: Therapeutic Advances in Gastroenterology Year: 2021 Reference: Therap Adv Gastroenterol. 2021 May 30;14:17562848211016567. doi: 10.1177/17562848211016567. eCollection 2021. Impact factor: 4.409 Publication type: Paper in international publication Authors: Campos-Varela, Isabel, Villagrasa, Ares, Simon-Talero, Macarena, Riveiro-Barciela, Mar, Ventura-Cots, Meritxell, Aguilera-Castro, Lara, Alvarez-Lopez, Patricia, Nordahl, Emilie A, Rivera-Esteban, Jesus M, Romero, Alba et al. DOI: 10.1177/17562848211016567
PMID: 34032928 Journal: ACTA DIABETOLOGICA Year: 2021 Reference: Acta Diabetol. 2021 Oct;58(10):1403-1412. doi: 10.1007/s00592-021-01735-5. Epub 2021 May 25. Impact factor: 4.28 Publication type: Paper in international publication Authors: Planas, Alejandra, Simo-Servat, Olga, Baneras, Jordi, Sanchez, Monica, Garcia, Esther, Ortiz, Angel M, Ruiz-Meana, Marisol, Hernandez, Cristina, Ferreira-Gonzalez, Ignacio, Simo, Rafael et al. DOI: 10.1007/s00592-021-01735-5
PMID: 31277226 Journal: Journal of Clinical Medicine Year: 2019 Reference: J Clin Med. 2019 Jul 3;8(7). pii: jcm8070964. doi: 10.3390/jcm8070964. Impact factor: 5.688 Publication type: Paper in international publication Authors: Ciudin, Andreea, Fidilio, Enzamaria, Ortiz, Angel, Pich, Sara, Salas, Eduardo, Mesa, Jordi, Hernandez, Cristina, Simo-Servat, Olga, Lecube, Albert, Simo, Rafael et al. DOI: 10.3390/jcm8070964
PMID: 31035251 Journal: ENDOCRINE-RELATED CANCER Year: 2019 Reference: Endocr Relat Cancer. 2019 Jul;26(7):R415-R439. doi: 10.1530/ERC-19-0093. Impact factor: 4.774 Publication type: Review in international publication Authors: Zafon Llopis, Carles, Gil, Joan, Perez-Gonzalez, Beatriz, Jorda, Mireia et al. DOI: 10.1530/ERC-19-0093
PMID: 30862093 Journal: Journal of Clinical Medicine Year: 2019 Reference: J Clin Med. 2019 Mar 11;8(3). pii: jcm8030339. doi: 10.3390/jcm8030339. Impact factor: 5.688 Publication type: Paper in international publication Authors: Sampedro, Joel, Bogdanov, Patricia, Ramos, Hugo, Sola-Adell, Cristina, Turch, Mireia, Valeri, Marta, Simo-Servat, Olga, Lagunas, Carmen, Simo, Rafael, Hernandez, Cristina et al. DOI: 10.3390/jcm8030339
PMID: 30400049 Journal: EUROPEAN JOURNAL OF ENDOCRINOLOGY Year: 2019 Reference: Eur J Endocrinol. 2019 Jan 1;180(1):21-29. doi: 10.1530/EJE-18-0624. Impact factor: 5.107 Publication type: Paper in international publication Authors: Fort, Jose M, Pujol-Borrell, Ricardo, Ramon Y Cajal, Santiago, Gonzalez, Oscar, Castell, Joan, Mesa, Jordi, Roca, Isabel, Caubet, Enric, Iglesias Felip, Carmela, Zafon, Carles et al. DOI: 10.1530/EJE-18-0624
PMID: 28687563 Journal: EUROPEAN JOURNAL OF ENDOCRINOLOGY Year: 2017 Reference: Eur J Endocrinol. 2017 Oct;177(4):309-317. doi: 10.1530/EJE-17-0243. Epub 2017 Jul 7. Impact factor: 4.101 Publication type: Paper in international publication Authors: Lopez-Alfonso, Ana, Capdevila, Jaume, Trigo, Jose Manuel, Aller, Javier, Manzano, Jose Luis, Garcia-Adrian, Silvia, Zafon, Carles, Reig, Oscar, Bohn, Uriel, Ramon Y Cajal, Teresa et al. DOI: 10.1530/EJE-17-0243
PMID: 28589087 Journal: European thyroid journal Year: 2017 Reference: Eur Thyroid J. 2017 Apr;6(2):65-74. doi: 10.1159/000457793. Epub 2017 Mar 3. Impact factor: 0 Publication type: Review in national publication Authors: Zafon, Carles, Diez, Juan J, Galofre, Juan C, Cooper, David S et al. DOI: 10.1159/000457793
PMID: 27278263 Journal: DIABETIC MEDICINE Year: 2017 Reference: Diabet Med. 2017 Jan;34(1):79-85. doi: 10.1111/dme.13161. Epub 2016 Jul 9. Impact factor: 3.054 Publication type: Paper in international publication Authors: Lecube, A, Romero, O, Sampol, G, Mestre, O, Ciudin, A, Sanchez, E, Hernandez, C, Caixas, A, Vigil, L, Simo, R et al. DOI: 10.1111/dme.13161
PMID: 28583767 Journal: Translational research : the journal of laboratory Year: 2017 Reference: Transl Res. 2017 Aug;186:19-35.e5. doi: 10.1016/j.trsl.2017.05.004. Epub 2017 May 18. Impact factor: 0 Publication type: Paper in international publication Authors: Errico, Teresa L, Mendez-Lara, Karen Alejandra, Santos, David, Cabrerizo, Nuria, Baila-Rueda, Lucia, Metso, Jari, Cenarro, Ana, Pardina, Eva, Lecube, Albert, Jauhiainen, Matti et al. DOI: 10.1016/j.trsl.2017.05.004
PMID: 27267343 Journal: BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE Year: 2016 Reference: Biochim Biophys Acta. 2016 Sep;1862(9):1663-74. doi: 10.1016/j.bbadis.2016.05.024. Epub 2016 Jun 4. Impact factor: 5.158 Publication type: Paper in international publication Authors: Garcia-Ramirez, Marta, Cazzoni, Daniele, de la Villa, Pedro, Sanchez-Fernandez, Elena M, Mellet, Carmen Ortiz, FGarcia Fernandez, Jose M, Hernandez, Cristina, Simo, Rafael, Valverde, Angela M, Alcalde-Estevez, Elena et al. DOI: 10.1016/j.bbadis.2016.05.024
PMID: 26764417 Journal: EUROPEAN JOURNAL OF ENDOCRINOLOGY Year: 2016 Reference: Eur J Endocrinol. 2016 Apr;174(4):465-72. doi: 10.1530/EJE-15-1119. Epub 2016 Jan 13. Impact factor: 3.892 Publication type: Paper in international publication Authors: Guillen-Grima, Francisco, Zafon, Carles, Galofre, Juan C, Llavero-Valero, Maria et al. DOI: 10.1530/EJE-15-1119
PMID: 26614398 Journal: HUMAN PATHOLOGY Year: 2016 Reference: Hum Pathol. 2016 Feb;48:132-41. doi: 10.1016/j.humpath.2015.09.020. Epub 2015 Oct 3. Impact factor: 2.791 Publication type: Paper in international publication Authors: Del Carmen, Sofia, Gatius, Sonia, Franch-Arcas, Guzman, Baena, Jose Antonio, Gonzalez, Oscar, Zafon, Carlos, Cuevas, Dolors, Valls, Joan, Perez, Angustias, Martinez, Mercedes et al. DOI: 10.1016/j.humpath.2015.09.020
PMID: 27051590 Journal: BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS Year: 2016 Reference: BBA Clin. 2016 Jan 8;5:54-65. doi: 10.1016/j.bbacli.2015.12.002. eCollection 2016 Jun. Impact factor: 4.864 Publication type: Paper in international publication Authors: Pardina, Eva, Ferrer, Roser, Baena-Fustegueras, Juan Antonio, Lecube, Albert, Fort, Jose Manuel, Caubet, Enric, Gonzalez, Oscar, Vilallonga, Ramon, Vargas, Victor, Balibrea, Jose Maria et al. DOI: 10.1016/j.bbacli.2015.12.002
PMID: 23333637 Journal: Endocrinologia y nutricion Year: 2013 Reference: Endocrinol Nutr. 2013 Oct;60(8):483-4. doi: 10.1016/j.endonu.2012.10.004. Epub 2013 Jan 18. Impact factor: Publication type: Letter or abstract Authors: Mesa, Jordi, Simo, Rafael, Hernandez, Cristina, Lecube, Albert, Ciudin, Andreea et al. DOI: 10.1016/j.endonu.2012.10.004
PMID: 23335850 Journal: MOLECULAR VISION Year: 2013 Reference: Mol Vis. 2013;19:47-53. Epub 2013 Jan 7. Impact factor: 1.987 Publication type: Paper in international publication Authors: Valverde, Angela M, Miranda, Soledad, Garcia-Ramirez, Marta, Gonzalez-Rodriguez, Agueda, Hernandez, Cristina, Simo, Rafael et al. DOI:
PMID: 22291997 Journal: PLoS One Year: 2012 Reference: PLoS One. 2012;7(1):e30599. Epub 2012 Jan 24. Impact factor: 4.092 Publication type: Paper in international publication Authors: Lecube, Albert, Baena-Fustegueras, Juan Antonio, Fort, Jose Manuel, Pelegri, Dolors, Hernandez, Cristina, Simo, Rafael et al. DOI: 10.1371/journal.pone.0030599
PMID: 22265762 Journal: Endocrinología y nutrición Year: 2012 Reference: Endocrinol Nutr. 2012 Feb;59(2):95-7. doi: 10.1016/j.endonu.2011.12.003. Epub 2012 Jan 21. Impact factor: Publication type: Letter or abstract Authors: , et al. DOI: 10.1016/j.endonu.2011.12.003
PMID: 21860806 Journal: Journal of thyroid research Year: 2012 Reference: J Thyroid Res. 2012;2012:530721. Epub 2011 Jul 19. Impact factor: Publication type: Letter or abstract Authors: Zafon, Carles, Obiols, Gabriel, Baena, Juan Antonio, Castellvi, Josep, Dalama, Belen, Mesa, Jordi et al. DOI: 10.1155/2012/530721
The European project, in which Vall d'Hebron participates, will favor personalized diagnosis and innovative therapeutic strategies in patients with the disease.
This investment from EIT Health in the project will enable D-Sight to progress in the clinical development of its groundbreaking treatment for the early stages of diabetic retinopathy.
This initiative of the ”la Caixa” Foundation offers the selected entrepreneurial scientists financial support and support through individual mentoring and training.