About the VHIR
Here at the Vall d'Hebron Research Institute (VHIR) we promote biomedical research, innovation and teaching. Over 1,800 people are seeking to understand diseases today so the treatment can be improved tomorrow.
Research
We are working to understand diseases, to find out how they operate and to create better treatments for patients. Get to know about our groups and their lines of research.
People
People are the centre of the Vall d'Hebron Research Institute (VHIR). This is why we are bound by the principles of freedom of research, gender equality and professional attitudes that HRS4R promotes.
Clinical trials
Our work is not just basic or translational; we are leaders in clinical research. Enter and find about the clinical trials we are conducting and why we are a world reference in this field.
Progress
Our aim is to make the research carried out at the Vall d’Hebron Research Institute (VHIR) a driving force for transformation. How? By identifying new channels and solutions for the promotion of people's health and well-being.
Core facilities
We offer specialist support for researchers, internal and external alike, ranging from specific services to preparing complete projects. All this, from a perspective of quality and speed of response.
News
We offer you a gateway for staying up to date on everything going on at the Vall d’Hebron Research Institute (VHIR), from the latest news to future solidarity activities and initiatives that we are organising.
The Clinical Biochemistry, Drug Delivery & Therapy (CB-DDT) group arises from the merger of two VHIR groups, the Clinical Biochemistry group and the Drug Delivery and Targeting group, which they develop preclinical and clinical research in the diagnosis and therapy of different diseases.
With a direct link to the Clinical Biochemistry service of the Vall d'Hebron Hospital, our scope of action ranges from the analysis of massive data coming from the service, the development of diagnostic and prognostic biomarkers, evaluation of existing therapies and the development of new therapeutic strategies based on nanotechnology.
In terms of specific pathologies or indications, the group has an extensive track record in basic and applied research in cancer (new biomarkers, therapeutic targets and new treatments), metabolopathies (biomarkers and improvements in enzyme replacement therapy), kidney disease and liver disease.
IP: Maria Jose Soler Romeo Collaborators: Oriol Bestard Matamoros, Sheila Bermejo Garcia, Concepció Jacobs Cachá, Elena Isabel Crespo Gimeno Funding agency: Instituto de Salud Carlos III Funding: 246840 Reference: AC22/00029 Duration: 01/01/2023 - 31/12/2025
IP: Francisco Rodríguez Frias Collaborators: David Tabernero Caellas Funding agency: GILEAD SCIENCES SLU Funding: 49961.71 Reference: GLD22/00080 Duration: 28/02/2023 - 27/02/2025
IP: Ibane Abasolo Olaortua Collaborators: José Antonio Arranz Amo, Raquel Barquin Del Pino, Laura Conesa Milian, Clara Ramírez Serra, Yolanda Villena Ortiz, Joan López Hellin, Albert Blanco Grau, Francisco Rodríguez Frias, Roser Ferrer Costa, Joaquin Seras Franzoso, Diego Baranda Martínez-Abasca, Laura Castillo Ribelles, Clara Carnicer Cáceres, Marina Giralt Arnaiz, Ana Gomez Garcia, Simon Schwartz Navarro, Pablo Gabriel Medina, Rosanna Paciucci Barzanti, Zamira Vanessa Diaz Riascos, Marc Miquel Moltó Abad, Laura Castellote Bellés, Daniel Bravo Nieto, Luz María Cruz Carlos, Clara Sanz Gea, Alba Estela García Fernández, Maria del Pilar Reimundo Diaz-Fierros, Belen Garcia Prats, Noelia Díaz Troyano, JAUME VIMA BOFARULL, Beatriz Pacín Ruíz, Fernanda Raquel Da Silva Andrade, Diana Fernandes de Rafael, Maria Francesca Cortese, Sandra Mancilla Zamora Funding agency: Agència Gestió Ajuts Universitaris i de Recerca Funding: 60000 Reference: 2021 SGR 01173 Duration: 01/01/2022 - 30/06/2025
IP: Oriol Bestard Matamoros Collaborators: Marina Lopez Martinez, Francesc Moreso Mateos, Natalia Ramos Terrades, Maria Jose Soler Romeo, Joana Sellarés Roig, Pamela Dominguez Baez, Vergara Arana, Ander, Irene Agraz Pamplona, Sheila Bermejo Garcia, Mariona Juvé Torres, Irina Betsabe Torres Rodriguez, Alba Torija Recasens, Concepció Jacobs Cachá, Elena Isabel Crespo Gimeno, Laura Donadeu Casassas, Carmen Llorens Cebriá, Nuria Bolaños Peruga, Manel Perelló Carrascosa, Maria Antonia Emilia Meneghini Funding agency: Agència Gestió Ajuts Universitaris i de Recerca Funding: 40000 Reference: 2021 SGR 00883 Duration: 01/01/2022 - 30/06/2025
PMID: 37745192 Journal: JHEP Reports Year: 2023 Reference: JHEP Rep. 2023 Jul 13;5(10):100842. doi: 10.1016/j.jhepr.2023.100842. eCollection 2023 Oct. Impact factor: Publication type: Paper in international publication Authors: Berg, Thomas; Bes, Marta; Buti, Maria; Buti, Maria; Casillas, Rosario; Esteban, Rafael; Esteban, Rafael; Palom, Adriana; Pfefferkorn, Maria; Rando-Segura, Ariadna et al. DOI: 10.1016/j.jhepr.2023.100842
PMID: 37760489 Journal: Cancers Year: 2023 Reference: Cancers (Basel). 2023 Sep 12;15(18):4520. doi: 10.3390/cancers15184520. Impact factor: Publication type: Paper in international publication Authors: Clar-Marmaneu, Helena; Garcia-Fernandez, Alba Estela; Garcia-Fernandez, Francisco Javier et al. DOI: 10.3390/cancers15184520
PMID: 37802652 Journal: SEXUALLY TRANSMITTED INFECTIONS Year: 2023 Reference: Sex Transm Infect. 2023 Oct 6:sextrans-2023-055899. doi: 10.1136/sextrans-2023-055899. Impact factor: Publication type: Paper in international publication Authors: Alvarez-Lopez, Patricia; Alvarez-Lopez, Patricia; Arando, Maider; Arando, Maider; Blanco-Grau, Albert; Curran, Adrian; Curran, Adrian; Descalzo, Vicente; El Ouazzani, Rachid; Garcia, Jorge Nestor et al. DOI: 10.1136/sextrans-2023-055899
PMID: 37808908 Journal: Frontiers in Cellular and Infection Microbiology Year: 2023 Reference: Front Cell Infect Microbiol. 2023 Sep 21;13:1175996. doi: 10.3389/fcimb.2023.1175996. eCollection 2023. Impact factor: Publication type: Review in international publication Authors: Quer, Josep; Rando-Segura, Ariadna; Rodriguez-Frias, Francisco et al. DOI: 10.3389/fcimb.2023.1175996
The European project, in which Vall d'Hebron participates, will favor personalized diagnosis and innovative therapeutic strategies in patients with the disease.
In total, different projects of six research groups will be promoted, focusing on precision medicine and advanced therapies.
During the last year, the collaboration between Vall d’Hebron and ZeClinics has found three nanobody candidates with potent anticancer properties in zebrafish model.