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Head and Neck Cancer: Biomedical Research Cancer Stem cells

The work of the Biomedical Research in Cancer Stem Cell group focuses mainly on senescence (replicative or stress-induced oncoge). In our laboratory, we carry out several genetic screens based on the detection of new genes / small interfering RNA (siRNA) / microRNAs related to cell proliferation, which have a role in cancer. Therefore, we use different cell models: murine cells, human primary cells or immortalized cells capable of entering senescence.

The objectives of the group are:

  • Identification and characterization of genes / microRNAs in mammary tumors associated with a more aggressive character (triple negative).
  • Identification and characterization of markers in lung, laryngeal and pharyngeal cancer with diagnostic and prognostic value that help to target a more specific chemotherapy treatment.
  • Identification and characterization of populations of cancer stem cells (CSC) in tumors resistant to conventional therapies.
  • Early detection of breast cancer before it manifests itself clinically.
  • Study of new genes involved in cancer from their identification in massive genetic scans at the basic level.

Team

Rebeca Murillo Torres

Rebeca Murillo Torres

Research technician
Head and Neck Cancer: Biomedical Research Cancer Stem cells
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Rebeca Murillo Torres

Rebeca Murillo Torres

Research technician
Head and Neck Cancer: Biomedical Research Cancer Stem cells
Read more
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News

Researchers from the Vall d’Hebron Research Institute (VHIR) have participated in a study showing that, after just a few seconds of illumination, the activated molecule prevents the formation of tumor spheres.

Experts addressed the main current and future challenges to improve therapeutic options for patients with this type of tumor.

The sessions were aimed at establishing new collaborations to advance the prevention and treatment of this type of tumour.