About the VHIR
Here at the Vall d'Hebron Research Institute (VHIR) we promote biomedical research, innovation and teaching. Over 1,800 people are seeking to understand diseases today so the treatment can be improved tomorrow.
Research
We are working to understand diseases, to find out how they operate and to create better treatments for patients. Get to know about our groups and their lines of research.
People
People are the centre of the Vall d'Hebron Research Institute (VHIR). This is why we are bound by the principles of freedom of research, gender equality and professional attitudes that HRS4R promotes.
Clinical trials
Our work is not just basic or translational; we are leaders in clinical research. Enter and find about the clinical trials we are conducting and why we are a world reference in this field.
Progress
Our aim is to make the research carried out at the Vall d’Hebron Research Institute (VHIR) a driving force for transformation. How? By identifying new channels and solutions for the promotion of people's health and well-being.
Core facilities
We offer specialist support for researchers, internal and external alike, ranging from specific services to preparing complete projects. All this, from a perspective of quality and speed of response.
News
We offer you a gateway for staying up to date on everything going on at the Vall d’Hebron Research Institute (VHIR), from the latest news to future solidarity activities and initiatives that we are organising.
Our research group is focused on studying the pathophysiology of migraine and other primary headaches using preclinical, translational and clinical research.
Migraine will allow us to define the brain’s adaptive, sensory/cognitive functions, through genetics, epigenetics, neurophysiology, neuromolecular and neuroanatomical information with an interest in developing clinical therapeutic solutions, with the goal on having an impact on suffering and increasing the well-being.
IP: Marta Vila Pueyo Collaborators: - Funding agency: Fundació "La Caixa" Funding: 305100 Reference: LCF/BQ/PI23/11970015 Duration: 31/12/2023 - 30/12/2026
IP: Patricia Pozo Rosich Collaborators: Alicia Alpuente Ruiz, Laila Asskour, Eulalia Gine Cipres, Victor José Gallardo Lopez, Edoardo Caronna Funding agency: Instituto de Salud Carlos III Funding: 369930 Reference: PMP22/00189 Duration: 01/01/2023 - 31/12/2025
IP: Patricia Pozo Rosich Collaborators: Alicia Alpuente Ruiz, Laila Asskour, Eulalia Gine Cipres, Marta Torres Ferrús, Victor José Gallardo Lopez, Nara Ikumi Montserrat, Marta Vila Pueyo, Edoardo Caronna Funding agency: Agència Gestió Ajuts Universitaris i de Recerca Funding: 0.01 Reference: 2021 SGR 00406 Duration: 01/01/2022 - 30/06/2025
IP: Marta Torres Ferrús Collaborators: Alicia Alpuente Ruiz, Laila Asskour, Eulalia Gine Cipres, Victor José Gallardo Lopez, Edoardo Caronna, Laura Gómez Dabó Funding agency: Instituto de Salud Carlos III Funding: 75020 Reference: PI22/01530 Duration: 01/01/2023 - 31/12/2025
PMID: 37728577 Journal: CEPHALALGIA Year: 2023 Reference: Cephalalgia. 2023 Sep;43(9):3331024231201577. doi: 10.1177/03331024231201577. Impact factor: Publication type: Review in international publication Authors: Choi, So Youn; Kim, Seung Ae; Lee, Mi Ji; Pozo-Rosich, Patricia; Pozo-Rosich, Patricia; Youn, Michelle Sojung et al. DOI: 10.1177/03331024231201577
PMID: 37786502 Journal: Future healthcare journal Year: 2023 Reference: Future Healthc J. 2023 Mar;10(1):46-49. doi: 10.7861/fhj.2022-0142. Impact factor: Publication type: Paper in international publication Authors: Aguilar, Anna Ochoa de Echaguen; Carbonell-Cobo, Marta; de Castro, Rodolfo; Hueto-Madrid, Juan Antonio; Paradell, Raquel Canovas; Pozo-Rosich, Patricia; Pozo-Rosich, Patricia; Rovira-Simon, Jordi; Sales-I-Coll, Marc; Shaw, Genevieve et al. DOI: 10.7861/fhj.2022-0142
PMID: 37791410 Journal: EUROPEAN JOURNAL OF NEUROLOGY Year: 2023 Reference: Eur J Neurol. 2023 Oct 4. doi: 10.1111/ene.16058. Impact factor: Publication type: Paper in international publication Authors: Alpuente, Alicia; Alpuente, Alicia; Caronna, Edoardo; Elosua-Bayes, Iker; Gallardo, Victor J; Gallardo, Victor J; Melgarejo, Laura; Pozo-Rosich, Patricia; Pozo-Rosich, Patricia; Rosell-Mirmi, Joana et al. DOI: 10.1111/ene.16058
PMID: 37795746 Journal: HEADACHE Year: 2023 Reference: Headache. 2023 Oct 5. doi: 10.1111/head.14629. Impact factor: Publication type: Paper in international publication Authors: Buse, Dawn C; Dabruzzo, Brett; Fanning, Kristina M; Lipton, Richard B; Orr, Serena L; Pozo-Rosich, Patricia; Pozo-Rosich, Patricia; Reed, Michael L et al. DOI: 10.1111/head.14629
PMID: 35791285 Journal: CEPHALALGIA Year: 2022 Reference: Cephalalgia. 2022 Jul 5:3331024221110102. doi: 10.1177/03331024221110102. Impact factor: 6.295 Publication type: Paper in international publication Authors: Steiner, Timothy J; Terwindt, Gisela M; Katsarava, Zaza; Pozo-Rosich, Patricia; Gantenbein, Andreas R; Roche, Sarah L; Dell'Agnello, Grazia; Tassorelli, Cristina et al. DOI: 10.1177/03331024221110102
PMID: 35815637 Journal: CEPHALALGIA Year: 2022 Reference: Cephalalgia. 2022 Jul 9:3331024221111772. doi: 10.1177/03331024221111772. Impact factor: 6.295 Publication type: Paper in international publication Authors: Pozo-Rosich, Patricia, Gallardo, Victor Jose, Caronna, Edoardo, Vila-Ballo, Adria, Marti-Marca, Angela, Cerda-Company, Xim, Ikumi, Nara et al. DOI: 10.1177/03331024221111772
PMID: 35678104 Journal: PSYCHOPHYSIOLOGY Year: 2022 Reference: Psychophysiology. 2022 Jun 9:e14108. doi: 10.1111/psyp.14108. Impact factor: 4.016 Publication type: Paper in international publication Authors: Pozo-Rosich, Patricia, Soto-Faraco, Salvador, Torralba Cuello, Mireia, Marti-Marca, Angela, Vila-Ballo, Adria et al. DOI: 10.1111/psyp.14108
PMID: 35670131 Journal: HEADACHE Year: 2022 Reference: Headache. 2022 Jun;62(6):648-649. doi: 10.1111/head.14330. Epub 2022 Jun 7. Impact factor: 5.887 Publication type: Letter or abstract Authors: Pozo-Rosich, Patricia, Caronna, Edoardo et al. DOI: 10.1111/head.14330
PMID: 34564833 Journal: Pain and Therapy Year: 2021 Reference: Pain Ther. 2021 Dec;10(2):1605-1618. doi: 10.1007/s40122-021-00328-y. Epub 2021 Sep 26. Impact factor: 5.725 Publication type: Paper in international publication Authors: Kamm, Katharina, Ruscheweyh, Ruth, Russo, Marco, Torelli, Paola, Filatova, Elena, Latysheva, Nina, Gryglas-Dworak, Anna, Straburzynski, Marcin, Butera, Calogera, Colombo, Bruno et al. DOI: 10.1007/s40122-021-00328-y
PMID: 34363619 Journal: HEADACHE Year: 2021 Reference: Headache. 2021 Sep;61(8):1277-1280. doi: 10.1111/head.14197. Epub 2021 Aug 7. Impact factor: 5.887 Publication type: Letter or abstract Authors: Torres-Ferrus, Marta, Pozo-Rosich, Patricia, Alpuente, Alicia, Caronna, Edoardo et al. DOI: 10.1111/head.14197
PMID: 34273945 Journal: JOURNAL OF HEADACHE AND PAIN Year: 2021 Reference: J Headache Pain. 2021 Jul 17;22(1):75. doi: 10.1186/s10194-021-01289-5. Impact factor: 7.277 Publication type: Paper in international publication Authors: Torres-Ferrus, Marta, Pareto, Deborah, Gallardo, Victor J, Cuberas-Borros, Gemma, Alpuente, Alicia, Caronna, Edoardo, Vila-Ballo, Adria, Lorenzo-Bosquet, Carles, Castell-Conesa, Joan, Rovira, Alex et al. DOI: 10.1186/s10194-021-01289-5
PMID: 34273947 Journal: JOURNAL OF HEADACHE AND PAIN Year: 2021 Reference: J Headache Pain. 2021 Jul 17;22(1):74. doi: 10.1186/s10194-021-01267-x. Impact factor: 7.277 Publication type: Paper in international publication Authors: Alberte-Woodward, Miguel, Jurado, Carmen, Oms, Teresa, Ezpeleta, David, de Teran, Javier Diaz, Morollon, Noemi, Latorre, German, Torres-Ferrus, Marta, Alpuente, Alicia, Lamas, Raquel et al. DOI: 10.1186/s10194-021-01267-x
PMID: 32652924 Journal: JOURNAL OF HEADACHE AND PAIN Year: 2020 Reference: J Headache Pain. 2020 Jul 11;21(1):88. doi: 10.1186/s10194-020-01157-8. Impact factor: 4.797 Publication type: Paper in international publication Authors: Torres-Ferrus, Marta, Gallardo, Victor Jose, Alpuente, Alicia, Pozo-Rosich, Patricia et al. DOI: 10.1186/s10194-020-01157-8
PMID: 32614067 Journal: ACTA NEUROLOGICA SCANDINAVICA Year: 2020 Reference: Acta Neurol Scand. 2020 Dec;142(6):555-562. doi: 10.1111/ane.13302. Epub 2020 Jul 29. Impact factor: 2.684 Publication type: Paper in international publication Authors: Caronna, Edoardo, Sanchez Corral, Anna, Santafe, Manel, Sueiras, Maria, Guzman, Lorena, Quintana, Manuel, Toledo-Argany, Manuel, Santamarina, Estevo, Gracia Gozalo, Rosa Maria, Vilaseca, Andreu et al. DOI: 10.1111/ane.13302
PMID: 32421912 Journal: EUROPEAN JOURNAL OF NEUROLOGY Year: 2020 Reference: Eur J Neurol. 2020 Oct;27(10):2102-2108. doi: 10.1111/ene.14331. Epub 2020 Jun 17. Impact factor: 4.516 Publication type: Paper in international publication Authors: Alpuente, Alicia, Gallardo, Victor Jose, Torres-Ferrus, Marta, Santos-Lasaosa, Sonia, Guerrero, Angel, Lainez, Jose Miguel, Viguera, Javier, Gago-Veiga, Ana, Irimia, Pablo, Del Rio, Margarita Sanchez et al. DOI: 10.1111/ene.14331
PMID: 32349653 Journal: JOURNAL OF HEADACHE AND PAIN Year: 2020 Reference: J Headache Pain. 2020 Apr 29;21(1):42. doi: 10.1186/s10194-020-01111-8. Impact factor: 4.797 Publication type: Review in international publication Authors: Lampl, C, van Hoogstraten, W S, Van den Abbeele, D, Torres-Ferrus, M, Ursitti, F, Alpuente-Ruiz, A, Brunello, F, Chiappino, D, de Vries, T, Di Marco, S et al. DOI: 10.1186/s10194-020-01111-8
PMID: 29771141 Journal: CEPHALALGIA Year: 2019 Reference: Cephalalgia. 2019 Jan;39(1):91-99. doi: 10.1177/0333102418777509. Epub 2018 May 17. Impact factor: 4.438 Publication type: Paper in international publication Authors: Torres-Ferrus, Marta, Vila-Sala, Carme, Quintana, Manuel, Ajanovic, Sara, Gallardo, Victor Jose, Gomez, Juan Bernardo, Alvarez-Sabin, Jose, Macaya, Alfons, Pozo-Rosich, Patricia et al. DOI: 10.1177/0333102418777509
Two international studies led by Vall d'Hebron recommend early administration of specific drugs to prevent migraine to achieve a better response to therapy.
On World Clinical Trials Day, we highlight some of the studies we have participated in that confirm the efficacy of new drugs, allowing their approval by regulatory agencies.
The study, conducted in more than 770 people, concludes that atogepant reduces the frequency of migraine attacks and the need to take medication.
