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Hepato-bilio-pancreatic surgery (HBP) and liver transplantation

Until 2017, this group was constituted as a consolidated group in the VHIR under the name of "Digestive Transplants" with a consolidated research trajectory. Our group has two large areas of research: liver transplantation, which is cross-sectional adult-pediatric and; on the other hand, research, specifically in the fields of liver resections, liver cancer (primary or metastatic), biliary cancer, pancreatic cancer and pancreatitis. Both areas have very innovative aspects, with translational objectives, including artificial intelligence, transcriptomics and molecular biology.

The general objective of the liver transplant research area is to improve the preservation of liver grafts, as well as increase the survival of grafts and transplant patients. The research area related to cancer or acute pancreatitis has as a general objective to improve the management and treatment of patients with pancreatitis, as well as to improve the diagnosis and survival of cancer patients.

Team

Maria Margaret Mercadal Hally

Maria Margaret Mercadal Hally

Research technician
Hepato-bilio-pancreatic surgery (HBP) and liver transplantation
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Carlos Mauricio Larrarte King

Carlos Mauricio Larrarte King

Research technician
Hepato-bilio-pancreatic surgery (HBP) and liver transplantation
Read more
Concepción Morillas Rodriguez

Concepción Morillas Rodriguez

Research technician
Hepato-bilio-pancreatic surgery (HBP) and liver transplantation
Read more
Cristina Padros Fornieles

Cristina Padros Fornieles

Research technician
Hepato-bilio-pancreatic surgery (HBP) and liver transplantation
Read more
Elizabeth Pando Rau

Elizabeth Pando Rau

Main researcher
Hepato-bilio-pancreatic surgery (HBP) and liver transplantation
Read more
Javier Juamperez Goñi

Javier Juamperez Goñi

Research assistant
Hepato-bilio-pancreatic surgery (HBP) and liver transplantation
Read more
Maria Margaret Mercadal Hally

Maria Margaret Mercadal Hally

Research technician
Hepato-bilio-pancreatic surgery (HBP) and liver transplantation
Read more
Carlos Mauricio Larrarte King

Carlos Mauricio Larrarte King

Research technician
Hepato-bilio-pancreatic surgery (HBP) and liver transplantation
Read more
Concepción Morillas Rodriguez

Concepción Morillas Rodriguez

Research technician
Hepato-bilio-pancreatic surgery (HBP) and liver transplantation
Read more
Cristina Padros Fornieles

Cristina Padros Fornieles

Research technician
Hepato-bilio-pancreatic surgery (HBP) and liver transplantation
Read more
Elizabeth Pando Rau

Elizabeth Pando Rau

Main researcher
Hepato-bilio-pancreatic surgery (HBP) and liver transplantation
Read more
Javier Juamperez Goñi

Javier Juamperez Goñi

Research assistant
Hepato-bilio-pancreatic surgery (HBP) and liver transplantation
Read more

Research lines

Infusió intraportal de cèl·lules mare hepàtiques

Podria restaurar la ureagènesi en pacients pediàtrics amb trastorns del cicle de la urea.

IP: Jesús Quintero Bernabeu, Javier Juamperez Goñi, Maria Margaret Mercadal Hally

Intel·ligència Artificial i malalties pancreàtiques

- PancreatIA-EmergencyCare: Algoritme de predicció de la gravetat de la pancreatitis aguda utilitzant "machine learning" i processament de imatges.

- PancreatIA-Cancer: Algoritme de predicció de recurrència del càncer de pàncreas post- cirurgia utilitzant "machine learning" i processament de imatges així como las mutacions genètiques del tumor.

IP: Elizabeth Pando Rau, Joaquin Balsells Valls

L'aplicació de la intel.ligencia artificial en la cuantificació de la esteatosi hepática en el donants de fetge.

El desenvolupament de algoritmes de “machine learning” de forma objectiva, ràpida i reproduïble, per detectar i quantificar el grau d´esteatosi. També plataforma d´entrenament d´algoritmes amb dades i imatges médiques.

IP: Concepción Gomez Gavara, Itxarone Izaskun Bilbao Aguirre, Elizabeth Pando Rau

L'estudi de l'evolució a nivell histològic dels empelts hepàtics

La seva correlació  amb dades clíniques, analítiques, d'imatge i amb un panell de miRNA (miR-155-5p, miR-122-5p, miR-181a -5p, miR-148-3p ) podria permetre la individualització del tractament immunosupressor.

IP: Jesús Quintero Bernabeu, Javier Juamperez Goñi, Maria Margaret Mercadal Hally

Projects

Estudio sobre fertilidad y embarazo tras cirugia por enfermedades enflamatorias intestinales

IP: Joaquin Balsells Valls
Collaborators: Gianluca Pellino
Funding agency: Asociación Española de Cirujanos
Funding: 5000
Reference: AEC/BECA/2022/IBD/FERTILITY
Duration: 18/10/2022 - 19/10/2025

THE APPLICATION OF ARTIFICIAL INTELLIGENCE METHODS FOR ORGANS ASSESSMENT

IP: Concepción Gomez Gavara
Collaborators: Ramon Charco Torra, Ernest Hidalgo Llompart, Enric Miret Alomar, Elizabeth Pando Rau
Funding agency: Agència Gestió Ajuts Universitaris i de Recerca
Funding: 0.01
Reference: 2021 SGR 01236
Duration: 01/01/2022 - 30/06/2025

Fisiologia i fisiopatologia digestiva

IP: Chaysavanh Manichanh
Collaborators: Itxarone Izaskun Bilbao Aguirre, Zaida Soler Luque, Jordi Barquinero Mañez, Oscar Segarra Canton, Gerard Serrano Gomez, Cristina Dopazo Taboada, Rocío Piñera Moreno
Funding agency: Agència Gestió Ajuts Universitaris i de Recerca
Funding: 40000
Reference: 2021 SGR 00459
Duration: 01/01/2022 - 30/06/2025

Modelos 3D innovadores derivados de tejido hepático humano para ensayos de desarrollo y toxicidad de fármacos

IP: Alberto Sandiumenge Camps
Collaborators: Ernest Hidalgo Llompart, Jesús Quintero Bernabeu
Funding agency: Ministerio de Ciencia e Innovación-MICINN
Funding: 124939
Reference: CPP2021-008633
Duration: 01/09/2022 - 06/08/2025

Ministerio de Ciencia
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News

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Funding has been obtained for 43 projects under the calls for Health R&D&I Projects, Health Technology Development, and Independent Clinical Research

L’aportació permet avançar en estudis de referència internacional i continuar millorant l’atenció dels infants trasplantats de fetge.