About the VHIR
Here at the Vall d'Hebron Research Institute (VHIR) we promote biomedical research, innovation and teaching. Over 1,800 people are seeking to understand diseases today so the treatment can be improved tomorrow.
Research
We are working to understand diseases, to find out how they operate and to create better treatments for patients. Get to know about our groups and their lines of research.
People
People are the centre of the Vall d'Hebron Research Institute (VHIR). This is why we are bound by the principles of freedom of research, gender equality and professional attitudes that HRS4R promotes.
Clinical trials
Our work is not just basic or translational; we are leaders in clinical research. Enter and find about the clinical trials we are conducting and why we are a world reference in this field.
Progress
Our aim is to make the research carried out at the Vall d’Hebron Research Institute (VHIR) a driving force for transformation. How? By identifying new channels and solutions for the promotion of people's health and well-being.
Core facilities
We offer specialist support for researchers, internal and external alike, ranging from specific services to preparing complete projects. All this, from a perspective of quality and speed of response.
News
We offer you a gateway for staying up to date on everything going on at the Vall d’Hebron Research Institute (VHIR), from the latest news to future solidarity activities and initiatives that we are organising.
The Infection and Immunity in pediatric patients research group is a multidisciplinary pediatric research group made up of health professionals involved in translational research in the field of pediatric infectious diseases and immunodeficiencies, two related fields in terms of pathophysiology and clinical implications. It is a consolidated research group recognized by the AGAUR and is the only one with the accreditation of the Jeffrey Modell Foundation in research in the field of primary immunodeficiencies throughout the state.
The group was officially created in 2010, belongs to the area of Infectious Diseases and participates in the transversal programs of Advanced Translational Immunology and Rare Diseases and actively participates in national and international competitive projects, carries out multiple academic and industry-linked clinical trials and has increased the number and quality in recent years. In addition, it has its own laboratory specially dedicated to advanced immune studies.
PMID: 37962334 Journal: ANTIMICROBIAL AGENTS AND CHEMOTHERAPY Year: 2023 Reference: Antimicrob Agents Chemother. 2023 Nov 14:e0082923. doi: 10.1128/aac.00829-23. Impact factor: Publication type: Paper in international publication Authors: Benitez-Carbante, Maria Isabel; Di Masso, Andres; Diaz de Heredia, Cristina; Fernandez Ledesma, Berta; Fernandez-Polo, Aurora; Grau Cerrato, Santiago; Luque Pardos, Sonia; Martin-Gomez, Maria Teresa; Melendo Perez, Susana; Mendoza-Palomar, Natalia et al. DOI: 10.1128/aac.00829-23
PMID: 37964360 Journal: BREAST CANCER RESEARCH Year: 2023 Reference: Breast Cancer Res. 2023 Nov 14;25(1):143. doi: 10.1186/s13058-023-01736-y. Impact factor: Publication type: Paper in international publication Authors: Baulida, Josep; Benitez-Carbante, Maria Isabel; Diaz de Heredia, Cristina; Eyras, Eduardo; Fernandez Ledesma, Berta; Fernandez-Polo, Aurora; Franco-Valls, Hector; Garcia de Herreros, Antonio; Grau Cerrato, Santiago; Iaconcig, Alessandra et al. DOI: 10.1186/s13058-023-01736-y
PMID: 38063508 Journal: PEDIATRIC INFECTIOUS DISEASE JOURNAL Year: 2023 Reference: Pediatr Infect Dis J. 2023 Dec 6. doi: 10.1097/INF.0000000000004176. Impact factor: Publication type: Paper in international publication Authors: Alarcon, Ana; Alonso-Ojembarrena, Almudena; Baquero-Artigao, Fernando; Benavides, Marta; Blazquez-Gamero, Daniel; Bringue, Xavier; Castells-Vilella, Laura; Del Valle, Rut; Esteva, Cristina; Fortuny, Claudia et al. DOI: 10.1097/INF.0000000000004176
So far, 240 volunteers have been recruited within all the centres set to join adolescents’ clinical trial (named HH3) to test the efficacy, tolerability, and safety of the BIMERVAX® COVID-19 vaccine in adolescents aged 12 to 17.
The results show that, in some patients with mutations in the X chromosome, the healthy gene is inactivated and the mutated gene manifests itself, which favors the onset of the disease.
The study, which is part of the European RECOMB project, is currently recruiting volunteers.
