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Infection and Immunity in pediatric patients

The Infection and Immunity in pediatric patients research group is a multidisciplinary pediatric research group made up of health professionals involved in translational research in the field of pediatric infectious diseases and immunodeficiencies, two related fields in terms of pathophysiology and clinical implications. It is a consolidated research group recognized by the AGAUR and is the only one with the accreditation of the Jeffrey Modell Foundation in research in the field of primary immunodeficiencies throughout the state.

The group was officially created in 2010, belongs to the area of Infectious Diseases and participates in the transversal programs of Advanced Translational Immunology and Rare Diseases and actively participates in national and international competitive projects, carries out multiple academic and industry-linked clinical trials and has increased the number and quality in recent years. In addition, it has its own laboratory specially dedicated to advanced immune studies.

Publications

Epigenetic profiling linked to multisystem inflammatory syndrome in children (MIS-C): A multicenter, retrospective study.

PMID: 35770252
Journal: EClinicalMedicine
Year: 2022
Reference: EClinicalMedicine. 2022 Jun 25;50:101515. doi: 10.1016/j.eclinm.2022.101515. eCollection 2022 Aug.
Impact factor: 0
Publication type: Paper in international publication
Authors: Davalos, Veronica; Garcia-Prieto, Carlos A; Alegria, Iosune; Aguilera-Albesa, Sergio; Valencia-Ramos, Juan; Rodriguez-Palmero, Agusti; Ruiz, Montserrat; Planas-Serra, Laura; Jordan, Iolanda; Ferrer, Gerardo et al.
DOI: 10.1016/j.eclinm.2022.101515

Common Variable Immunodeficiency and Neurodevelopmental Delay Due to a 13Mb Deletion on Chromosome 4 Including the NFKB1 Gene: A Case Report.

PMID: 35784294
Journal: Frontiers in Immunology
Year: 2022
Reference: Front Immunol. 2022 Jun 17;13:897975. doi: 10.3389/fimmu.2022.897975. eCollection 2022.
Impact factor: 7.561
Publication type: Letter or abstract
Authors: Valenzuela, Irene; Franco-Jarava, Clara; Colobran, Roger; Batlle-Maso, Laura; Castells, Neus; Dieli-Crimi, Romina; Martinez-Gallo, Monica; Garcia-Prat, Marina; Riviere, Jacques G; Soler-Palacin, Pere et al.
DOI: 10.3389/fimmu.2022.897975

Recessive inborn errors of type I IFN immunity in children with COVID-19 pneumonia.

PMID: 35708626
Journal: JOURNAL OF EXPERIMENTAL MEDICINE
Year: 2022
Reference: J Exp Med. 2022 Aug 1;219(8). pii: 213287. doi: 10.1084/jem.20220131. Epub 2022 Jun 16.
Impact factor: 14.307
Publication type: Paper in international publication
Authors: El Baghdadi, Jamila, Bohlen, Jonathan, Liu, Zhiyong, Moncada-Velez, Marcela, Kendir-Demirkol, Yasemin, Jing, Huie, Bizien, Lucy, Marchal, Astrid, Abolhassani, Hassan, Delafontaine, Selket et al.
DOI: 10.1084/jem.20220131

The risk of COVID-19 death is much greater and age-dependent with type I IFN autoantibodies.

PMID: 35043109
Journal:
Year: 2022
Reference: Res Sq. 2022 Jan 14. doi: 10.21203/rs.3.rs-1225906/v1.
Impact factor: 0
Publication type: Letter or abstract
Authors: Riviere, Jacques G, Garcia-Prat, Marina, Parra-Martinez, Alba, Soler-Palacin, Pere et al.
DOI: 10.21203/rs.3.rs-1225906/v1

Treatment of Multisystem Inflammatory Syndrome in Children.

PMID: 34133854
Journal: NEW ENGLAND JOURNAL OF MEDICINE
Year: 2021
Reference: N Engl J Med. 2021 Jul 1;385(1):11-22. doi: 10.1056/NEJMoa2102968. Epub 2021 Jun 16.
Impact factor: 91.253
Publication type: Paper in international publication
Authors: Cruces, Pablo, McArdle, Andrew J, Vito, Ortensia, Patel, Harsita, Seaby, Eleanor G, Shah, Priyen, Wilson, Clare, Broderick, Claire, Nijman, Ruud, Tremoulet, Adriana H et al.
DOI: 10.1056/NEJMoa2102968

Enterovirus-A71 Rhombencephalitis Outbreak in Catalonia: Characteristics, Management and Outcome.

PMID: 34097655
Journal: PEDIATRIC INFECTIOUS DISEASE JOURNAL
Year: 2021
Reference: Pediatr Infect Dis J. 2021 Jul 1;40(7):628-633. doi: 10.1097/INF.0000000000003114.
Impact factor: 2.129
Publication type: Paper in international publication
Authors: Anton, Andres, Castellarnau, Ester, Delgado, Ignacio, Vazquez, Elida, Gonzalez, Sebastia, Mayol, Lluis, Mendez, Maria, Sole, Eduard, Rosal, Jaume, Andres, Cristina et al.
DOI: 10.1097/INF.0000000000003114

Atypical Inflammatory Syndrome Triggered by SARS-CoV-2 in Infants with Down Syndrome.

PMID: 34089457
Journal: JOURNAL OF CLINICAL IMMUNOLOGY
Year: 2021
Reference: J Clin Immunol. 2021 Oct;41(7):1457-1462. doi: 10.1007/s10875-021-01078-4. Epub 2021 Jun 5.
Impact factor: 8.317
Publication type: Paper in international publication
Authors: Riviere, Jacques G, Malle, Louise, Bastard, Paul, Martin-Nalda, Andrea, Carpenter, Taya, Bush, Douglas, Patel, Roosheel, Colobran, Roger, Soler-Palacin, Pere, Casanova, Jean-Laurent et al.
DOI: 10.1007/s10875-021-01078-4

[SARS-CoV-2 PCR negativization in respiratory sample in patients with need for recurring assistance].

PMID: 33775582
Journal: ANALES DE PEDIATRIA
Year: 2021
Reference: An Pediatr (Engl Ed). 2021 Jan 27. pii: S1695-4033(21)00012-6. doi: 10.1016/j.anpedi.2021.01.006.
Impact factor: 1.5
Publication type: Letter whit IF
Authors: Bassets-Bosch, Alba, Raya-Munoz, Judith, Worner-Tomasa, Nuria, Melendo-Perez, Susana, Gonzalez-Peris, Sebastia et al.
DOI: 10.1016/j.anpedi.2021.01.006

Blog

News

The study seeks to better understand blood disorders in children and young people, analyzing the role of immunological alterations to improve diagnosis and treatment.

Members of the RBDCOV project, which involves VHIR, gathered at the Palau Macaya to review progress and achievements made during the final phase of the project.

During the meeting, the role of the Vall d'Hebron Paediatric Research Hub in promoting research on children and adolescents was highlighted.