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Infection and Immunity in pediatric patients

The Infection and Immunity in pediatric patients research group is a multidisciplinary pediatric research group made up of health professionals involved in translational research in the field of pediatric infectious diseases and immunodeficiencies, two related fields in terms of pathophysiology and clinical implications. It is a consolidated research group recognized by the AGAUR and is the only one with the accreditation of the Jeffrey Modell Foundation in research in the field of primary immunodeficiencies throughout the state.

The group was officially created in 2010, belongs to the area of Infectious Diseases and participates in the transversal programs of Advanced Translational Immunology and Rare Diseases and actively participates in national and international competitive projects, carries out multiple academic and industry-linked clinical trials and has increased the number and quality in recent years. In addition, it has its own laboratory specially dedicated to advanced immune studies.

Publications

Impact of JAK Inhibitors in Pediatric Patients with STAT1 Gain of Function (GOF) Mutations-10 Children and Review of the Literature.

PMID: 35486339
Journal: JOURNAL OF CLINICAL IMMUNOLOGY
Year: 2022
Reference: J Clin Immunol. 2022 Apr 29. pii: 10.1007/s10875-022-01257-x. doi: 10.1007/s10875-022-01257-x.
Impact factor: 8.317
Publication type: Paper in international publication
Authors: Martin-Nalda, Andrea, Alsina, Laia, Neth, Olaf, Olbrich, Peter, Martinez Pomar, Natalia, Lopez-Corbeto, Mireia, Garcia-Garcia, Ana, Kanderova, Veronika, Deya-Martinez, Angela, Riviere, Jaques G et al.
DOI: 10.1007/s10875-022-01257-x

SARS-CoV-2 PCR negativization in respiratory sample in patients with need for recurring assistance.

PMID: 35305952
Journal: ANALES DE PEDIATRIA
Year: 2022
Reference: An Pediatr (Engl Ed). 2022 Apr;96(4):357-359. doi: 10.1016/j.anpede.2021.01.008. Epub 2022 Mar 3.
Impact factor: 1.5
Publication type: Letter whit IF
Authors: Bassets-Bosch, Alba, Raya-Munoz, Judith, Worner-Tomasa, Nuria, Melendo-Perez, Susana, Gonzalez-Peris, Sebastia et al.
DOI: 10.1016/j.anpede.2021.01.008

Dynamics of RT-PCR and Serologic Test Results in Children with SARS-CoV-2 Infection.

PMID: 34571020
Journal: JOURNAL OF PEDIATRICS
Year: 2022
Reference: J Pediatr. 2022 Feb;241:126-132.e3. doi: 10.1016/j.jpeds.2021.09.029. Epub 2021 Sep 25.
Impact factor: 4.406
Publication type: Paper in international publication
Authors: Perez, Seoane B, Tagarro, A, Sanz-Santaeufemia, F J, Grasa, C, Cobos, E, Yebra, J, Alonso-Cadenas, J A, Baquero-Artigao, F, Mesa, Guzman Jm, Reinoso, T et al.
DOI: 10.1016/j.jpeds.2021.09.029

Curation and Expansion of Human Phenotype Ontology for Defined Groups of Inborn Errors of Immunity.

PMID: 33991581
Journal: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
Year: 2022
Reference: J Allergy Clin Immunol. 2022 Jan;149(1):369-378. doi: 10.1016/j.jaci.2021.04.033. Epub 2021 May 12.
Impact factor: 10.793
Publication type: Paper in international publication
Authors: Riviere, Jacques G, van der Burg, Mirjam, Gattorno, Marco, Seidel, Markus G, Burns, Siobhan, Warnatz, Klaus, Hauck, Fabian, Brogan, Paul, Gilmour, Kimberly C, Schuetz, Catharina et al.
DOI: 10.1016/j.jaci.2021.04.033

Prescription quality of prolonged antibiotherapy in pediatrics. Impact of ASP program interventions.

PMID: 32229130
Journal: ENFERMEDADES INFECCIOSAS Y MICROBIOLOGIA CLINICA
Year: 2021
Reference: Enferm Infecc Microbiol Clin. 2021 Mar;39(3):134-138. doi: 10.1016/j.eimc.2020.02.015. Epub 2020 Mar 27.
Impact factor: 1.731
Publication type: Paper in national publication
Authors: Melendo, Susana, Fernandez-Polo, Aurora, Castellnou Asens, Ivette, Mendoza-Palomar, Natalia, Barnes-Mayolas, Meritxell, Soler-Palacin, Pere, Soler Palacin, Pere, Melendo Perez, Susana, Mendoza Palomar, Natalia, Nieves Larrosa Escartin, M et al.
DOI: 10.1016/j.eimc.2020.02.015

Failure of Viral-Specific T Cells Administered in Pre-transplant Settings in Children with Inborn Errors of Immunity.

PMID: 33462728
Journal: JOURNAL OF CLINICAL IMMUNOLOGY
Year: 2021
Reference: J Clin Immunol. 2021 May;41(4):748-755. doi: 10.1007/s10875-020-00961-w. Epub 2021 Jan 18.
Impact factor: 8.317
Publication type: Paper in international publication
Authors: Alonso, Laura, Mendez-Echevarria, Ana, Rudilla, Francesc, Mozo, Yasmina, Soler-Palacin, Pere, Sisinni, Luisa, Bueno, David, Riviere, Jacques, de Paz, Raquel, Sanchez-Zapardiel, Elena et al.
DOI: 10.1007/s10875-020-00961-w

Blog

News

The study seeks to better understand blood disorders in children and young people, analyzing the role of immunological alterations to improve diagnosis and treatment.

Members of the RBDCOV project, which involves VHIR, gathered at the Palau Macaya to review progress and achievements made during the final phase of the project.

During the meeting, the role of the Vall d'Hebron Paediatric Research Hub in promoting research on children and adolescents was highlighted.