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Infectious Diseases

The VHIR Infectious Diseases research group is made up of medical professionals, with healthcare and clinical or basic translational research activities; of Biomedicine dedicated to basic research; and Nursing, with activities to support clinical research.

The group's lines of research are mainly focused on four areas:

Infections related to immunosuppression. Includes infectious diseases related to immunocompromised patients, solid organ or hematopoietic stem cell transplant recipients and recipients of biological therapies.

Sexually transmitted diseases, including HIV infection and other highly prevalent infections in our country (syphilis, gonorrhea, lymphogranuloma venere or infections caused by the human papillomavirus).

Infections related to health care, with special emphasis on those difficult to treat (cardiovascular infections or infections related to prosthetic materials) or caused by multi-resistant pathogens (MDRO) or affecting vulnerable populations.

Global Health and Tropical Diseases with special emphasis on prevalent diseases in our environment that affect the immigrant or displaced population.

Team

Joan Gavaldà Santapau

Joan Gavaldà Santapau

Main researcher
Infectious Diseases
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Joan Martínez Campreciós

Joan Martínez Campreciós

Predoctoral researcher
Infectious Diseases
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Joaquin Burgos Cibrian

Joaquin Burgos Cibrian

Main researcher
Infectious Diseases
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Jordi Gómez i Prat

Jordi Gómez i Prat

Infectious Diseases
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Jordi Navarro Mercadé

Jordi Navarro Mercadé

Main researcher
Infectious Diseases
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Jose Santos Santiago

Jose Santos Santiago

Infectious Diseases
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Joan Gavaldà Santapau

Joan Gavaldà Santapau

Main researcher
Infectious Diseases
Read more
Joan Martínez Campreciós

Joan Martínez Campreciós

Predoctoral researcher
Infectious Diseases
Read more
Joaquin Burgos Cibrian

Joaquin Burgos Cibrian

Main researcher
Infectious Diseases
Read more
Jordi Gómez i Prat

Jordi Gómez i Prat

Infectious Diseases
Read more
Jordi Navarro Mercadé

Jordi Navarro Mercadé

Main researcher
Infectious Diseases
Read more
Jose Santos Santiago

Jose Santos Santiago

Infectious Diseases
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Publications

Effectiveness of Fosfomycin for the Treatment of Multidrug-Resistant Escherichia coli Bacteremic Urinary Tract Infections: A Randomized Clinical Trial.

PMID: 35024838
Journal: JAMA Network Open
Year: 2022
Reference: JAMA Netw Open. 2022 Jan 4;5(1):e2137277. doi: 10.1001/jamanetworkopen.2021.37277.
Impact factor: 8.485
Publication type: Paper in international publication
Authors: Almirante, Benito, Natera-Kindelan, Clara, Sorli, Luisa, Borrell, Nuria, Giner-Oncina, Livia, Amador-Prous, Concha, Shaw, Evelyn, Jover-Saenz, Alfredo, Molina, Jose, Martinez-Alvarez, Rosa M et al.
DOI: 10.1001/jamanetworkopen.2021.37277

Evaluation of SARS-CoV-2 entry, inflammation and new therapeutics in human lung tissue cells.

PMID: 35025963
Journal: PLoS Pathogens
Year: 2022
Reference: PLoS Pathog. 2022 Jan 13;18(1):e1010171. doi: 10.1371/journal.ppat.1010171. eCollection 2022 Jan.
Impact factor: 6.823
Publication type: Paper in international publication
Authors: Grau-Exposito, Judith, Perea, David, Suppi, Marina, Massana, Nuria, Vergara, Ander, Soler, Maria Jose, Trinite, Benjamin, Blanco, Julia, Garcia-Perez, Javier, Alcami, Jose et al.
DOI: 10.1371/journal.ppat.1010171

Evolving mortality and clinical outcomes of hospitalized subjects during successive COVID-19 waves in Catalonia, Spain.

PMID: 35018339
Journal: Journal of Epidemiology and Global Health
Year: 2022
Reference: Glob Epidemiol. 2022 Jan 7:100071. doi: 10.1016/j.gloepi.2022.100071.
Impact factor: 1.719
Publication type: Paper in international publication
Authors: Gudiol, Carlota, Moreno, Anna Maria, Morales-Rull, Jose Luis, Rexach, Maria, Sabater, Gladis, Auguet, Teresa, Vidal, Francesc, Lerida, Ana, Rebull, Josep, Khunti, Kamlesh et al.
DOI: 10.1016/j.gloepi.2022.100071

Detection of Plasmodium falciparum malaria in 1 h using a simplified enzyme-linked immunosorbent assay.

PMID: 33648654
Journal: ANALYTICA CHIMICA ACTA
Year: 2021
Reference: Anal Chim Acta. 2021 Apr 1;1152:338254. doi: 10.1016/j.aca.2021.338254. Epub 2021 Jan 30.
Impact factor: 6.558
Publication type: Paper in international publication
Authors: de la Serna, Erica, Arias-Alpizar, Kevin, Borgheti-Cardoso, Livia Neves, Sanchez-Cano, Ana, Sulleiro, Elena, Zarzuela, Francesc, Bosch-Nicolau, Pau, Salvador, Fernando, Molina, Israel, Ramirez, Miriam et al.
DOI: 10.1016/j.aca.2021.338254

Imported cystic echinococcosis in Spain: a systematic review.

PMID: 33631003
Journal: TRANSACTIONS OF THE ROYAL SOCIETY OF TROPICAL MEDICINE AND HYGIENE
Year: 2021
Reference: Trans R Soc Trop Med Hyg. 2021 Oct 1;115(10):1184-1189. doi: 10.1093/trstmh/trab022.
Impact factor: 2.184
Publication type: Review in international publication
Authors: Zabala, Andrea, Salvador, Fernando, Sanchez-Montalva, Adrian, Bosch-Nicolau, Pau, Escola-Verge, Laura, Espinosa-Pereiro, Juan, Molina, Israel et al.
DOI: 10.1093/trstmh/trab022

Screening for asymptomatic STIs in HIV-infected men who have sex with men.

PMID: 32753480
Journal: SEXUALLY TRANSMITTED INFECTIONS
Year: 2021
Reference: Sex Transm Infect. 2021 Mar;97(2):170-171. doi: 10.1136/sextrans-2020-054560. Epub 2020 Aug 4.
Impact factor: 3.519
Publication type: Paper in international publication
Authors: Willekens, Rein, Sanchez, Irene, Miguel, Lucia, Esperalba, Juliana, Serra-Pladevall, Judit, Martin, Mario, Navarro, Jordi, Falco, Vicenc, Burgos, Joaquin, Ribera, Esteban et al.
DOI: 10.1136/sextrans-2020-054560

Dynamics of creatinine estimated glomerular filtration rate using one or more antiretrovirals that inhibit creatinine tubular secretion.

PMID: 33501995
Journal: JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
Year: 2021
Reference: J Antimicrob Chemother. 2021 Mar 12;76(4):1046-1050. doi: 10.1093/jac/dkaa547.
Impact factor: 5.79
Publication type: Paper in international publication
Authors: Ryan, Pablo, Perez Elias, Maria Jesus, Alejos, Belen, Gutierrez, Maria Mar, Crespo, Manuel, Knobel, Hernando, Ferrando, Ramon, Crespo, Manuel, Ocampo, Antonio, Sanz, Jose et al.
DOI: 10.1093/jac/dkaa547

Effectiveness of boosted darunavir plus rilpivirine in patients with long-lasting HIV-1 infection: DARIL study.

PMID: 32134108
Journal: JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
Year: 2020
Reference: J Antimicrob Chemother. 2020 Jul 1;75(7):1955-1960. doi: 10.1093/jac/dkaa072.
Impact factor: 5.439
Publication type: Paper in international publication
Authors: Navarro, Jordi, Gonzalez-Cordon, Ana, Casado, Jose Luis, Bernardino, Jose I, Domingo, Pere, Portilla, Joaquin, Llibre, Josep Maria, Colomer, Joan, Rial-Crestelo, David, Vizcarra, Pilar et al.
DOI: 10.1093/jac/dkaa072

Screening for Trypanosoma cruzi infection in immigrants and refugees: Systematic review and recommendations from the Spanish Society of Infectious Diseases and Clinical Microbiology.

PMID: 32127121
Journal: Eurosurveillance
Year: 2020
Reference: Euro Surveill. 2020 Feb;25(8). doi: 10.2807/1560-7917.ES.2020.25.8.1900393.
Impact factor: 6.454
Publication type: Paper in international publication
Authors: Velasco, Maria, Gimeno-Feliu, Luis Andres, Molina, Israel, Salas-Coronas, Joaquin, Sola, Ivan, Monge-Maillo, Begona, Torrus-Tendero, Diego, Cayla, Joan, de Guzman, Ena Nino, Arellano, Jl Perez et al.
DOI: 10.2807/1560-7917.ES.2020.25.8.1900393

Schistosomiasis in children: review of 51 imported cases in Spain.

PMID: 31821494
Journal: JOURNAL OF TRAVEL MEDICINE
Year: 2020
Reference: J Travel Med. 2020 Feb 3;27(1). pii: 5671715. doi: 10.1093/jtm/taz099.
Impact factor: 7.089
Publication type: Paper in international publication
Authors: Mendoza-Palomar, Natalia, Sulleiro, Elena, Perez-Garcia, Irene, Espiau, Maria, Soriano-Arandes, Antoni, Martin-Nalda, Andrea, Espasa, Mateu, Zarzuela, Francesc, Soler-Palacin, Pere et al.
DOI: 10.1093/jtm/taz099

Risk of infection associated with new therapies for the treatment of lymphoproliferative syndromes.

PMID: 31771856
Journal: MEDICINA CLINICA
Year: 2020
Reference: Med Clin (Barc). 2020 Feb 14;154(3):101-107. doi: 10.1016/j.medcli.2019.07.026. Epub 2019 Nov 23.
Impact factor: 1.635
Publication type: Review in national publication
Authors: Ruiz-Camps, Isabel, Aguilar-Company, Juan, Los-Arcos, Ibai et al.
DOI: 10.1016/j.medcli.2019.07.026

Novel tp0548 sequence-type of Treponema pallidum identified in Barcelona, Spain.

PMID: 30461599
Journal: SEXUALLY TRANSMITTED DISEASES
Year: 2019
Reference: Sex Transm Dis. 2019 May;46(5):e50-e52. doi: 10.1097/OLQ.0000000000000947.
Impact factor: 2.27
Publication type: Paper in international publication
Authors: Arando, Maider, Espasa, Mateu, Anton, Andres, Gimferrer, Laura, Pinana, Maria, Fernandez-Huerta, Miguel, Gonzalez-Lopez, Juan Jose, Serra-Pladevall, Judit, Pumarola, Tomas, Vall-Mayans, Marti et al.
DOI: 10.1097/OLQ.0000000000000947

Epidemiology and diagnosis of pleural tuberculosis in a low incidence country with high rate of immigrant population: A retrospective study.

PMID: 30449728
Journal: INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES
Year: 2019
Reference: Int J Infect Dis. 2019 Jan;78:34-38. doi: 10.1016/j.ijid.2018.10.005. Epub 2018 Oct 25.
Impact factor: 3.538
Publication type: Paper in international publication
Authors: Macias, Antonio, Sanchez-Montalva, Adrian, Salvador, Fernando, Villar, Ana, Tortola, Teresa, Saborit, Nuria, Molina, Israel et al.
DOI: 10.1016/j.ijid.2018.10.005

Plasmodium malariae in a Spanish traveller returning from Colombia.

PMID: 30924870
Journal: JOURNAL OF TRAVEL MEDICINE
Year: 2019
Reference: J Travel Med. 2019 Jun 1;26(4). pii: 5423127. doi: 10.1093/jtm/taz022.
Impact factor: 4.155
Publication type: Paper in international publication
Authors: Oliveira, I, Aznar, M L, Zarzuela, F, Sulleiro, E, Trevino, B, Serre, N, Pou, D, Salvador, F, Sanchez-Montalva, A, Bosch-Nicolau, P et al.
DOI: 10.1093/jtm/taz022

Lung transplantation in two cystic fibrosis patients infected with previously pandrug-resistant Burkholderia cepacia complex treated with ceftazidime-avibactam.

PMID: 30565008
Journal: INFECTION
Year: 2019
Reference: Infection. 2019 Apr;47(2):289-292. doi: 10.1007/s15010-018-1261-y. Epub 2018 Dec 19.
Impact factor: 2.927
Publication type: Paper in international publication
Authors: Roman, Antonio, Los-Arcos, Ibai, Len, Oscar, Martin-Gomez, Maria Teresa, Gonzalez-Lopez, Juan Jose, Saez-Gimenez, Berta, Deu, Maria, Nuvials, Xavier, Ferrer, Ricard, Gavalda, Joan et al.
DOI: 10.1007/s15010-018-1261-y

Ultrasound findings and associated factors to morbidity in Schistosoma haematobium infection in a highly endemic setting.

PMID: 29205689
Journal: TROPICAL MEDICINE & INTERNATIONAL HEALTH
Year: 2018
Reference: Trop Med Int Health. 2018 Feb;23(2):221-228. doi: 10.1111/tmi.13020. Epub 2017 Dec 20.
Impact factor: 2.541
Publication type: Paper in international publication
Authors: Garcia, Cristina Bocanegra, Pintar, Zeferino, Serres, Xavier, Mendioroz, Jacobo, Moreno, Milagros, Gallego, Sara, Lopez, Teresa, Soriano-Arandes, Antoni, Aznar, Maria Luisa, Sikaleta, Nicolau et al.
DOI: 10.1111/tmi.13020

Prevalence and molecular characterization of Strongyloides stercoralis, Giardia duodenalis, Cryptosporidium spp., and Blastocystis spp. isolates in school children in Cubal, Western Angola.

PMID: 29378626
Journal: Parasites & Vectors
Year: 2018
Reference: Parasit Vectors. 2018 Jan 29;11(1):67. doi: 10.1186/s13071-018-2640-z.
Impact factor: 3.163
Publication type: Paper in international publication
Authors: Aznar-Ruiz-de-Alegria, Maria L, Espasa, Mateu, Ninda, Arlette, Gandasegui, Javier, Sulleiro, Elena, Moreno, Milagros, Salvador, Fernando, Molina, Israel, Rodriguez, Esperanza, Carmena, David et al.
DOI: 10.1186/s13071-018-2640-z

Recommendations for Management of Endemic Diseases and Travel Medicine in Solid-Organ Transplant Recipients and Donors: Latin America - Map Gallery.

PMID: 29381582
Journal: TRANSPLANTATION
Year: 2018
Reference: Transplantation. 2018 Feb;102(2S Suppl 2):S81. doi: 10.1097/TP.0000000000002031.
Impact factor: 3.96
Publication type: Paper in international publication
Authors: Mourao, Paulo Henrique Orlandi, Gavalda, Joan, Salvador, Fernando, Molina, Israel et al.
DOI: 10.1097/TP.0000000000002031

Tuberculosis Recommendations for Solid Organ Transplant Recipients and Donors.

PMID: 29381579
Journal: TRANSPLANTATION
Year: 2018
Reference: Transplantation. 2018 Feb;102(2S Suppl 2):S60-S65. doi: 10.1097/TP.0000000000002014.
Impact factor: 3.96
Publication type: Paper in international publication
Authors: Santoro-Lopes, Guilherme, Subramanian, Aruna K, Molina, Israel, Aguado, Jose Maria, Rabagliatti, Ricardo, Len, Oscar et al.
DOI: 10.1097/TP.0000000000002014

Risk factors, survival, and impact of prophylaxis length in cytomegalovirus-seropositive lung transplant recipients: A prospective, observational, multicenter study.

PMID: 28294487
Journal: Transplant Infectious Disease
Year: 2017
Reference: Transpl Infect Dis. 2017 Jun;19(3). doi: 10.1111/tid.12694. Epub 2017 May 9.
Impact factor: 1.719
Publication type: Paper in international publication
Authors: Cifrian, J M, Pastor, A, Roman, Antonio, Ussetti, Piedad, Redel-Montero, Javier, Borro, J M, Sole, A, Monforte, Victor, Sintes, Helena, Lopez-Gallo, C et al.
DOI: 10.1111/tid.12694

Levofloxacin versus azithromycin for treating legionella pneumonia: a propensity score analysis.

PMID: 28267637
Journal: CLINICAL MICROBIOLOGY AND INFECTION
Year: 2017
Reference: Clin Microbiol Infect. 2017 Sep;23(9):653-658. doi: 10.1016/j.cmi.2017.02.030. Epub 2017 Mar 6.
Impact factor: 5.292
Publication type: Paper in international publication
Authors: Garcia-Vidal, Carolina, Sanchez-Rodriguez, Irene, Simonetti, Antonella Francesca, Burgos, Joaquin, Viasus, Diego, Martin, Maria Teresa, Falco, Vicenc, Carratala, Jordi et al.
DOI: 10.1016/j.cmi.2017.02.030

Erratum to "EPICO 3.0. Empirical antifungal therapy in critically-ill hematology patients" [Rev Iberoam Micol. 33 (4) (2016) 206-215].

PMID: 28249672
Journal: REVISTA IBEROAMERICANA DE MICOLOGIA
Year: 2017
Reference: Rev Iberoam Micol. 2017 Jan - Mar;34(1):62. doi: 10.1016/j.riam.2017.02.003.
Impact factor: 1.33
Publication type: Letter or abstract
Authors: Llinares, Pedro, Ruiz, Isabel, Zaragoza, Rafael, Ferrer, Ricard, Rodriguez, Alejandro H, Maseda, Emilio, Grau, Santiago et al.
DOI: 10.1016/j.riam.2017.02.003

Risk factors of high-grade anal intraepithelial neoplasia recurrence in HIV-infected men who have sex with men.

PMID: 28252530
Journal: AIDS
Year: 2017
Reference: AIDS. 2017 Jun 1;31(9):1245-1252. doi: 10.1097/QAD.0000000000001433.
Impact factor: 5.003
Publication type: Paper in international publication
Authors: Burgos, Joaquin, Curran, Adria, Landolfi, Stefania, Guelar, Ana, Miguel, Lucia, Dinares, MCarmen, Villar, Judith, Navarro, Jordi, Hernandez-Losa, Javier, Falco, Vicenc et al.
DOI: 10.1097/QAD.0000000000001433

Impact of the MIC of piperacillin/tazobactam on the outcome for patients with bacteraemia due to Enterobacteriaceae: the Bacteraemia-MIC project.

PMID: 26538507
Journal: JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
Year: 2016
Reference: J Antimicrob Chemother. 2016 Feb;71(2):521-30. doi: 10.1093/jac/dkv362. Epub 2015 Nov 3.
Impact factor: 4.919
Publication type: Paper in international publication
Authors: Causse, Manuel, Gutierrez-Gutierrez, Belen, Roberts, Jason A, Farkas, Andras, Pascual, Alvaro, Rodriguez-Bano, Jesus, de Cueto, Marina, Planes Reig, Ana Maria, Quintano, Fe Tubau, Praena, Julia et al.
DOI: 10.1093/jac/dkv362

Impact of influenza season and environmental factors on the clinical presentation and outcome of invasive pneumococcal disease.

PMID: 25109886
Journal: EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES
Year: 2015
Reference: Eur J Clin Microbiol Infect Dis. 2015 Jan;34(1):177-86. doi: 10.1007/s10096-014-2221-9. Epub 2014 Aug 12.
Impact factor: 2.668
Publication type: Paper in international publication
Authors: Burgos, J, Larrosa, M N, Martinez, A, Belmonte, J, Gonzalez-Lopez, J, Rello, J, Pumarola, T, Pahissa, A, Falco, V et al.
DOI: 10.1007/s10096-014-2221-9

Influence of Virulence Genotype and Resistance Profile in the Mortality of Pseudomonas aeruginosa Bloodstream Infections.

PMID: 25378459
Journal: CLINICAL INFECTIOUS DISEASES
Year: 2015
Reference: Clin Infect Dis. 2015 Feb 15;60(4):539-48. doi: 10.1093/cid/ciu866. Epub 2014 Nov 6.
Impact factor: 8.886
Publication type: Paper in international publication
Authors: Rodriguez-Bano, Jesus, Rodriguez-Lopez, Fernando, Tubau, Fe, Martinez-Martinez, Luis, Oliver, Antonio, Calbo, Esther, Granados, Ana, Pomar, Virginia, Pena, Carmen, Cabot, Gabriel et al.
DOI: 10.1093/cid/ciu866

Ventilator-associated respiratory infection following lung transplantation.

PMID: 25359351
Journal: EUROPEAN RESPIRATORY JOURNAL
Year: 2015
Reference: Eur Respir J. 2015 Mar;45(3):726-37. doi: 10.1183/09031936.00095214. Epub 2014 Oct 30.
Impact factor: 7.636
Publication type: Paper in international publication
Authors: Riera, Jordi, Caralt, Berta, Lopez, Iker, Augustin, Salvador, Roman, Antonio, Gavalda, Joan, Rello, Jordi et al.
DOI: 10.1183/09031936.00095214

Serum galactomannan versus a combination of galactomannan and polymerase chain reaction-based Aspergillus DNA detection for early therapy of invasive aspergillosis in high-risk hematological patients: a randomized controlled trial.

PMID: 25336623
Journal: CLINICAL INFECTIOUS DISEASES
Year: 2015
Reference: Clin Infect Dis. 2015 Feb 1;60(3):405-14. doi: 10.1093/cid/ciu833. Epub 2014 Oct 21.
Impact factor: 8.886
Publication type: Clinical Trials
Authors: Suarez, Maria, Aguado, Jose Maria, Vazquez, Lourdes, Fernandez-Ruiz, Mario, Villaescusa, Teresa, Ruiz-Camps, Isabel, Barba, Pere, Silva, Jose T, Batlle, Montserrat, Solano, Carlos et al.
DOI: 10.1093/cid/ciu833

Daptomycin is effective as antibiotic-lock therapy in a model of Staphylococcus aureus catheter-related infection.

PMID: 24412247
Journal: J INFECTION
Year: 2014
Reference: J Infect. 2014 Jun;68(6):548-52. doi: 10.1016/j.jinf.2014.01.001. Epub 2014 Jan 8.
Impact factor: 4.017
Publication type: Paper in international publication
Authors: Meije, Yolanda, Almirante, Benito, Del Pozo, Jose Luis, Martin, Maria Teresa, Fernandez-Hidalgo, Nuria, Shan, Adriana, Basas, Jana, Pahissa, Albert, Gavalda, Joan et al.
DOI: 10.1016/j.jinf.2014.01.001

Blog

News

The meeting was an opportunity to get to know projects from both institutions and to promote interaction between professionals.

On European Antibiotic Awareness Day, we highlight the importance of using these medications responsibly and finding innovative solutions to combat this issue.

Vall d'Hebron has coordinated this initiative that has carried out numerous training and community awareness activities aimed at empowering young people in sexual and reproductive health issues.