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Microbiology

The Microbiology research group of the Vall d'Hebron Research Institute (VHIR) focuses on the study of microbiological aspects —in basic, translational and clinical research— that could improve the outcome of patients with infectious diseases.

Our priority research areas are:

  • Microbiological surveillance of emerging and re-emerging infectious diseases.
    • Diseases due to viral infections of the respiratory tract
    • Microorganisms that cause vaccine-preventable diseases
    • Infectious diseases of sexual transmission
  • Antimicrobial resistance
  • Sepsis
  • Development and validation of rapid microbiological diagnostic devices.
  • International Health
  • Hepatitis 

We actively collaborate with other microbiology laboratories, health services, national and international centres and organizations, as well as with the different research networks of the Carlos III Health Institute in Spain.

In addition, we carry out an important activity in the surveillance of the genotypic and phenotypic evolution of microorganisms present in the community in terms of their virulence, transmissibility, antigenic escape and antimicrobial resistance, in collaboration with public administrations, both at the national and international level.
 

Team

Yesilkoy Filiz

Yesilkoy Filiz

Senior researcher
Microbiology
Read more
Yesilkoy Filiz

Yesilkoy Filiz

Senior researcher
Microbiology
Read more

Publications

In-Host HEV Quasispecies Evolution Shows the Limits of Mutagenic Antiviral Treatments.

PMID: 38139013
Journal: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Year: 2023
Reference: Int J Mol Sci. 2023 Dec 6;24(24):17185. doi: 10.3390/ijms242417185.
Impact factor:
Publication type: Paper in international publication
Authors: Adombi, Caroline Melanie; Buti, Maria; Campos, Carolina; Colomer-Castell, Sergi; Cortese, Maria Francesca; Esteban, Juan Ignacio; Garcia-Cehic, Damir; Gregori, Josep; Ibanez-Lligona, Marta; Quer, Josep et al.
DOI: 10.3390/ijms242417185

Epidemiological and Genetic Characterization of Norovirus Outbreaks That Occurred in Catalonia, Spain, 2017-2019.

PMID: 35336893
Journal: Viruses-Basel
Year: 2022
Reference: Viruses. 2022 Feb 27;14(3). pii: v14030488. doi: 10.3390/v14030488.
Impact factor: 5.048
Publication type: Paper in international publication
Authors: Razquin, Efren, Cornejo Sanchez, Thais, Bartolome, Rosa, Torner, Nuria, Izquierdo, Conchita, Soldevila, Nuria, Coronas, Lorena, Dominguez, Angela, Fuentes, Cristina, Pinto, Rosa M et al.
DOI: 10.3390/v14030488

Inspecting the Ribozyme Region of Hepatitis Delta Virus Genotype 1: Conservation and Variability.

PMID: 35215809
Journal: Viruses-Basel
Year: 2022
Reference: Viruses. 2022 Jan 22;14(2). pii: v14020215. doi: 10.3390/v14020215.
Impact factor: 5.048
Publication type: Paper in international publication
Authors: Rodriguez-Frias, Francisco, Pacin-Ruiz, Beatriz, Cortese, Maria Francesca, Tabernero, David, Sopena, Sara, Gregori, Josep, Garcia-Garcia, Selene, Najarro, Adrian, Aldama, Unai, Palom, Adriana et al.
DOI: 10.3390/v14020215

Respiratory Syncytial Virus Infections in Young Children Presenting to Primary Care in Catalonia During the COVID-19 Pandemic.

PMID: 34922377
Journal: Journal of the Pediatric Infectious Diseases Socie
Year: 2022
Reference: J Pediatric Infect Dis Soc. 2022 Feb 23;11(2):69-72. doi: 10.1093/jpids/piab121.
Impact factor: 3.164
Publication type: Paper in international publication
Authors: Coma, Ermengol, Vila, Jorgina, Mendez-Boo, Leonardo, Anton, Andres, Mora, Nuria, Fina, Francesc, Fabregas, Mireia, Medina, Manuel et al.
DOI: 10.1093/jpids/piab121

Multicenter clinical evaluation of a novel transcription-mediated amplification assay for SARS-CoV-2 molecular testing.

PMID: 35185236
Journal: ENFERMEDADES INFECCIOSAS Y MICROBIOLOGIA CLINICA
Year: 2022
Reference: Enferm Infecc Microbiol Clin. 2022 Feb 14. pii: S0213-005X(22)00024-6. doi: 10.1016/j.eimc.2022.01.014.
Impact factor: 1.731
Publication type: Paper in national publication
Authors: Camara, Jordi, Anton, Andres, Fernandez-Huerta, Miguel, Salmeron, Paula, Hernandez-Hermida, Yolanda, Andres, Cristina, Niubo, Jordi, Calatayud, Laura, Angeles Dominguez, M, Pumarola, Tomas et al.
DOI: 10.1016/j.eimc.2022.01.014

Peripheral and lung resident memory T cell responses against SARS-CoV-2.

PMID: 34021148
Journal: Nature Communications
Year: 2021
Reference: Nat Commun. 2021 May 21;12(1):3010. doi: 10.1038/s41467-021-23333-3.
Impact factor: 14.919
Publication type: Paper in international publication
Authors: Perea, David, Rosado, Joel, Falco, Anna, Kirkegaard, Cristina, Torrella, Ariadna, Planas, Bibiana, Navarro, Jordi, Suanzes, Paula, Alvarez-Sierra, Daniel, Ayora, Alfonso et al.
DOI: 10.1038/s41467-021-23333-3

Role of asymptomatic bacteriuria on early periprosthetic joint infection after hip hemiarthroplasty. BARIFER randomized clinical trial.

PMID: 33864153
Journal: EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES
Year: 2021
Reference: Eur J Clin Microbiol Infect Dis. 2021 Nov;40(11):2411-2419. doi: 10.1007/s10096-021-04241-2. Epub 2021 Apr 16.
Impact factor: 3.267
Publication type: Paper in international publication
Authors: Rodriguez-Pardo, Dolors, Del Toro, Maria Dolores, Guio-Carrion, Laura, Escudero-Sanchez, Rosa, Fernandez-Sampedro, Marta, Garcia-Viejo, Miguel Angel, Velasco-Arribas, Maria, Soldevila-Boixader, Laura, Femenias, Magdalena, Iribarren, Jose Antonio et al.
DOI: 10.1007/s10096-021-04241-2

Infectious complications of non-surgical biliary tract manipulation in paediatric patients. Role of antibiotic prophylaxis.

PMID: 33715879
Journal: ENFERMEDADES INFECCIOSAS Y MICROBIOLOGIA CLINICA
Year: 2021
Reference: Enferm Infecc Microbiol Clin (Engl Ed). 2021 Mar 11. pii: S0213-005X(21)00045-8. doi: 10.1016/j.eimc.2021.01.019.
Impact factor: 1.731
Publication type: Paper in national publication
Authors: Soria-Navarro, Beatriz, Mendoza-Palomar, Natalia, Juamperez-Gomi, Javier, Melendo, Susana, Mercadal-Hally, Maria, Lung, Mayli, Perez, Maria Mercedes, Quintero, Jesus, Soler-Palacin, Pere et al.
DOI: 10.1016/j.eimc.2021.01.019

Evaluation of the performance of Loopamp Trypanosoma cruzi Detection Kit for the diagnosis of Chagas disease in a non-endemic area, Spain.

PMID: 33692137
Journal: JOURNAL OF CLINICAL MICROBIOLOGY
Year: 2021
Reference: J Clin Microbiol. 2021 Apr 20;59(5). pii: JCM.01860-20. doi: 10.1128/JCM.01860-20. Print 2021 Apr 20.
Impact factor: 5.948
Publication type: Paper in international publication
Authors: Flores-Chavez, Maria D, Abras, Alba, Ballart, Cristina, Ibanez Perez, Ismael, Perez-Gordillo, Pilar, Gallego, Montserrat, Moure, Zaira, Sulleiro Igual, Elena, Nieto, Javier, Garcia Diez, Emilia et al.
DOI: 10.1128/JCM.01860-20

Clinical Outcomes of a Zika Virus Mother-Child Pair Cohort in Spain.

PMID: 32392815
Journal: Pathogens
Year: 2020
Reference: Pathogens. 2020 May 7;9(5). pii: pathogens9050352. doi: 10.3390/pathogens9050352.
Impact factor: 3.018
Publication type: Paper in international publication
Authors: Soler-Palacin, Pere, Espiau, Maria, Salazar, Ainara, Guarch-Ibanez, Borja, Vazquez, Ana, Navarro-Moron, Juan, Ramos-Amador, Jose-Tomas, Martin-Nalda, Andrea, Duenas, Eva, Blazquez-Gamero, Daniel et al.
DOI: 10.3390/pathogens9050352

Necrotizing fasciitis in haematological patients: a different scenario.

PMID: 32399706
Journal: ANNALS OF HEMATOLOGY
Year: 2020
Reference: Ann Hematol. 2020 Aug;99(8):1741-1747. doi: 10.1007/s00277-020-04061-y. Epub 2020 May 12.
Impact factor: 2.904
Publication type: Paper in international publication
Authors: Albasanz-Puig, A, Rodriguez-Pardo, D, Pigrau, C, Lung, M, Roldan, E, Corona, P S, Almirante, B, Ruiz-Camps, I et al.
DOI: 10.1007/s00277-020-04061-y

Effect of antiviral treatment in older patients hospitalized with confirmed influenza.

PMID: 32234540
Journal: ANTIVIRAL RESEARCH
Year: 2020
Reference: Antiviral Res. 2020 Jun;178:104785. doi: 10.1016/j.antiviral.2020.104785. Epub 2020 Mar 29.
Impact factor: 4.101
Publication type: Paper in international publication
Authors: Martin, Vicente, Egurrola, Mikel, Morales Suarez-Varela, Maria, Dominguez, Angela, Mayoral, J M, Diaz-Borrego, J, Morillo, A, Perez-Lozano, M J, Gutierrez, J, Perez-Ruiz, M et al.
DOI: 10.1016/j.antiviral.2020.104785

Hospital-acquired influenza infections detected by a surveillance system over six seasons, from 2010/2011 to 2015/2016.

PMID: 31992207
Journal: BMC INFECTIOUS DISEASES
Year: 2020
Reference: BMC Infect Dis. 2020 Jan 28;20(1):80. doi: 10.1186/s12879-020-4792-7.
Impact factor: 2.688
Publication type: Paper in international publication
Authors: Barrabeig, I, Godoy, P, Soldevila, N, Rius, C, Jane, M, Martinez, A, Cayla, J A, Dominguez, A, Alseda, M, Alvarez, J et al.
DOI: 10.1186/s12879-020-4792-7

The challenge of the laboratory diagnosis in a confirmed congenital Zika virus syndrome in utero: A case report.

PMID: 31096455
Journal: MEDICINE
Year: 2019
Reference: Medicine (Baltimore). 2019 May;98(20):e15532. doi: 10.1097/MD.0000000000015532.
Impact factor: 1.87
Publication type: Paper in international publication
Authors: Pumarola, Tomas, Soler-Palacin, Pere, Soriano-Arandes, Antoni, Martinon-Torres, Federico, Alarcon, Ana, Melendo, Susana, Sulleiro, Elena, Frick, Marie Antoinette, Rodo, Carlota, Espasa, Mateu et al.
DOI: 10.1097/MD.0000000000015532

Imported strongyloidiasis: Data from 1245 cases registered in the +REDIVI Spanish Collaborative Network (2009-2017).

PMID: 31095570
Journal: PLoS Neglected Tropical Diseases
Year: 2019
Reference: PLoS Negl Trop Dis. 2019 May 16;13(5):e0007399. doi: 10.1371/journal.pntd.0007399. eCollection 2019 May.
Impact factor: 4.487
Publication type: Paper in international publication
Authors: Salvador, Fernando, Trevino, Begona, Chamorro-Tojeiro, Sandra, Sanchez-Montalva, Adrian, Herrero-Martinez, Juan Maria, Rodriguez-Guardado, Azucena, Serre-Delcor, Nuria, Torrus, Diego, Goikoetxea, Josune, Zubero, Zurine et al.
DOI: 10.1371/journal.pntd.0007399

Retrospective Study of Cystic Echinococcosis in a Recent Cohort of a Referral Center for Liver Surgery.

PMID: 30242646
Journal: JOURNAL OF GASTROINTESTINAL SURGERY
Year: 2019
Reference: J Gastrointest Surg. 2019 Jun;23(6):1148-1156. doi: 10.1007/s11605-018-3971-y. Epub 2018 Sep 21.
Impact factor: 2.686
Publication type: Paper in international publication
Authors: Escola-Verge, Laura, Salvador, Fernando, Escudero-Fernandez, Jose Miguel, Sanchez-Montalva, Adrian, Sulleiro, Elena, Rando, Ariadna, Bilbao, Itxarone, Lazaro, Jose Luis, Serres, Xavier, Salvador, Josep et al.
DOI: 10.1007/s11605-018-3971-y

Recombinant CV-A6 strains related to hand-foot-mouth disease and herpangina at primary care centers (Barcelona, Spain).

PMID: 31033351
Journal: Future Microbiology
Year: 2019
Reference: Future Microbiol. 2019 Apr;14:499-507. doi: 10.2217/fmb-2018-0336. Epub 2019 Apr 29.
Impact factor: 2.746
Publication type: Paper in international publication
Authors: Fuentes, Francisco, Rubio, Susana, Pumarola, Tomas, Anton, Andres, Martin, Maria Carmen, Rodrigo, Carlos, Esperalba, Juliana, Andres, Cristina, Guasch, Eulalia, Pinana, Maria et al.
DOI: 10.2217/fmb-2018-0336

Acute periprosthetic joint infection due to Fusobacterium nucleatum in a non-immunocompromised patient. Failure using a Debridement, Antibiotics + Implant retention approach.

PMID: 29307651
Journal: ANAEROBE
Year: 2018
Reference: Anaerobe. 2018 Feb;49:116-120. doi: 10.1016/j.anaerobe.2017.12.010. Epub 2018 Jan 5.
Impact factor: 2.742
Publication type: Paper in international publication
Authors: Corona, Pablo S, Lung, Mayli, Pigrau, Carles, Soldado, Francisco, Amat, Carles, Carrera, Luis, Rodriguez-Pardo, Dolors et al.
DOI: 10.1016/j.anaerobe.2017.12.010

Zika virus dynamics in body fluids and risk of sexual transmission in a non-endemic area.

PMID: 29194880
Journal: TROPICAL MEDICINE & INTERNATIONAL HEALTH
Year: 2018
Reference: Trop Med Int Health. 2018 Jan;23(1):92-100. doi: 10.1111/tmi.13019. Epub 2017 Dec 21.
Impact factor: 2.541
Publication type: Paper in international publication
Authors: Molina, Israel, Almirante, Benito, Pumarola, Tomas, Serre, Nuria, Rando, Ariadna, Sanchez-Montalva, Adrian, Pou, Diana, Sulleiro, Elena, Salvador, Fernando, Bocanegra, Cristina et al.
DOI: 10.1111/tmi.13019

Blog

News

On European Antibiotic Awareness Day, we highlight the importance of using these medications responsibly and finding innovative solutions to combat this issue.

The new diagnostic method, designed for use in endemic regions, combines a mobile application with a low-cost robotic microscope.

The European network EUPertStrain celebrates its annual meeting, focused on the study of the evolution of Bordetella pertussis, the bacterium responsible for this disease that can be very serious in children under one year.