About the VHIR
Here at the Vall d'Hebron Research Institute (VHIR) we promote biomedical research, innovation and teaching. Over 1,800 people are seeking to understand diseases today so the treatment can be improved tomorrow.
Research
We are working to understand diseases, to find out how they operate and to create better treatments for patients. Get to know about our groups and their lines of research.
People
People are the centre of the Vall d'Hebron Research Institute (VHIR). This is why we are bound by the principles of freedom of research, gender equality and professional attitudes that HRS4R promotes.
Clinical trials
Our work is not just basic or translational; we are leaders in clinical research. Enter and find about the clinical trials we are conducting and why we are a world reference in this field.
Progress
Our aim is to make the research carried out at the Vall d’Hebron Research Institute (VHIR) a driving force for transformation. How? By identifying new channels and solutions for the promotion of people's health and well-being.
Core facilities
We offer specialist support for researchers, internal and external alike, ranging from specific services to preparing complete projects. All this, from a perspective of quality and speed of response.
News
We offer you a gateway for staying up to date on everything going on at the Vall d’Hebron Research Institute (VHIR), from the latest news to future solidarity activities and initiatives that we are organising.
The Microbiome Research’s group seeks to investigate the role of the microbiota in health and disease. Its secondary objectives include developing molecular as well as bioinformatics tools to characterize the microbiome structure and function, discovering micro-biomarkers for diagnosis and prognosis, investigating how fecal microbiota transplantation could be used as a therapeutic strategy, and evaluating the impact of diet on the gut microbial ecosystem The Microbiome Lab is a multidisciplinary team, composed of molecular biologists, bioinformaticians, and physicians. The group tackles several clinical fields including inflammatory bowel diseases, diabetes, liver diseases, pre-term birth, and critical illness.
The Microbiome Research Group seeks to investigate the role of the microbiota in health and disease. Its secondary objectives include:
1. Role of the microbiota in health and disease
2. Tools to characterize the microbiome structure and function
3. Micro-biomarkers for diagnosis and prognosis
4. Fecal microbiota transplantation as a therapeutic strategy
5. Impact of diet on the gut microbial ecosystem
IP: Chaysavanh Manichanh
IP: Chaysavanh Manichanh Collaborators: Zaida Soler Luque, Laura Campderros Traver, Sara Vega Abellaneda, Luis Fernando Mayorga Ayala Funding agency: Ministerio de Ciencia e Innovación-MICINN Funding: 237500 Reference: PID2023-147387OB-I00 Duration: 01/09/2024 - 31/08/2027
IP: Chaysavanh Manichanh Collaborators: Itxarone Izaskun Bilbao Aguirre, Zaida Soler Luque, Jordi Barquinero Mañez, Oscar Segarra Canton, Gerard Serrano Gomez, Cristina Dopazo Taboada, Rocío Piñera Moreno Funding agency: Agència Gestió Ajuts Universitaris i de Recerca Funding: 40000 Reference: 2021 SGR 00459 Duration: 01/01/2022 - 30/06/2025
IP: Chaysavanh Manichanh Collaborators: Laura Campderros Traver, Judit Álvarez González Funding agency: Instituto de Salud Carlos III Funding: 95000 Reference: CD22/00177 Duration: 01/03/2023 - 28/02/2025
IP: Laia Perez Lasarte Collaborators: Gerard Serrano Gomez, Chaysavanh Manichanh, Judit Álvarez González Funding agency: Fundació Institut de Recerca HUVH Funding: 56357.41 Reference: VHIR/PHDPROGRAMME/2022/SERRANO Duration: 01/07/2022 - 30/09/2025
PMID: 38189256 Journal: mSystems Year: 2024 Reference: mSystems. 2024 Jan 8:e0095023. doi: 10.1128/msystems.00950-23. Impact factor: Publication type: Paper in international publication Authors: Manichanh, Chaysavanh; Molano, Leidy-Alejandra G; Vega-Abellaneda, Sara et al. DOI: 10.1128/msystems.00950-23
PMID: 37026745 Journal: Hepatology Communications Year: 2023 Reference: Hepatol Commun. 2023 Apr 4;7(4):e0072. doi: 10.1097/HC9.0000000000000072. eCollection 2023 Apr 1. Impact factor: Publication type: Paper in international publication Authors: Alvarado, Edilmar; Canalda-Baltrons, Aleix; Claria, Joan; Cuyas, Berta; Escorsell, Angels; Guarner, Carlos; Laghi, Luca; Lan, Qiuyu; Manichanh, Chaysavanh; Nieto, Juan Camilo et al. DOI: 10.1097/HC9.0000000000000072
PMID: 37342265 Journal: Frontiers in Endocrinology Year: 2023 Reference: Front Endocrinol (Lausanne). 2023 Jun 5;14:1074757. doi: 10.3389/fendo.2023.1074757. eCollection 2023. Impact factor: Publication type: Paper in international publication Authors: Amodru, Vincent; Fernandez, Pedro Gonzalez; Gaztambide, Sonia; Manichanh, Chaysavanh; Martel-Duguech, Luciana; Puig-Domingo, Manel; Valassi, Elena; Webb, Susan M; Yanez, Francisca et al. DOI: 10.3389/fendo.2023.1074757
PMID: 37655859 Journal: INFLAMMATORY BOWEL DISEASES Year: 2023 Reference: Inflamm Bowel Dis. 2023 Sep 1;29(9):1362-1369. doi: 10.1093/ibd/izad058. Impact factor: Publication type: Paper in international publication Authors: Alonso, Virginia Robles; Casellas, Francesc; Casellas, Francesc; Guarner, Francisco; Herrera-deGuise, Claudia; Herrera-deGuise, Claudia; Manichanh, Chaysavanh; Mayorga, Luis Fernando; Pozuelo Del Rio, Marta; Pozuelo Del Rio, Marta et al. DOI: 10.1093/ibd/izad058
PMID: 38012160 Journal: Nature Communications Year: 2023 Reference: Nat Commun. 2023 Nov 27;14(1):7770. doi: 10.1038/s41467-023-43652-x. Impact factor: Publication type: Paper in international publication Authors: Alonso, Fabiola; Arpa, Berta; Aunon, Pilar; Corral-Pujol, Marta; Cosovanu, Catalina; Egia-Mendikute, Leire; Garcia, Patricia; Garcia-Carro, Clara; Gutierrez, Eduardo; Manichanh, Chaysavanh et al. DOI: 10.1038/s41467-023-43652-x
PMID: 35764931 Journal: BMC GASTROENTEROLOGY Year: 2022 Reference: BMC Gastroenterol. 2022 Jun 28;22(1):320. doi: 10.1186/s12876-022-02392-w. Impact factor: 3.067 Publication type: Paper in international publication Authors: Batista, Lissette; Robles, Virginia; Manichanh, Chaysavanh; Ruiz, Laura; Pinsach, Ferran; Guarner, Francisco; Fernandez-Banares, Fernando; Guagnozzi, Danila et al. DOI: 10.1186/s12876-022-02392-w
The study also linked improved microbiota diversity to better liver function.
This work sets the basis for future research aimed at a deeper understanding of the microbiota and the effect of nutrition.
These are the results of a study published in Nature Communications and led by the Vall d'Hebron Research Institute (VHIR), the University of Lleida (UdL) and the Biomedical Research Institute of Lleida (IRBLleida).
Check the current rates of the services offered by the Microbiome Research group
We are looking for approximately 1,000 volunteers who will have to answer a very simple questionnaire about their eating habits and provide a stool sample, 3 times over the course of a year.
